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nd development of new ideas. It provides not only office and lab space but also free mentoring assistance to new businesses in science, technology and social innovation. While there are probably no chickens hatching at MaRS, it wouldn't be at all surprising to find a company working on, say, a vaccine for bird flu. Approximately 20 incubator companies are currently housed at MaRS, including Clera Inc. - which is developing treatments for schizophrenia and depression; AXS Biomedical Animations Studio - a company that creates 3D medical animation for biomedical research and other applications; and Kanata Chemical Technologies (KCT), which has had great success developing catalysts for the chemical industry (catalysts speed up chemical reactions without being changed or consumed in those reactions

All of the above definitions could apply to the wider innovation community connected with the MaRS Centre. Located in the heart of Toronto's Discovery District - a 2.5 sq. kilometre downtown research district, MaRS is a non-profit environment for the birt

KCT founder and president Kamal Abdur-Rashid came to Canada in 1997 with a degree from the University of the West Indies

Canada has always had to fight hard to attract talent and investment

MaRS Vital to Toronto's life sciences vision is MaRS (derived from Medical and Related Sciences) a non-profit organisation and business centre located in the heart of the city. Its core function is as a biotech incubator and business park, known as MaRS Discovery District. The venture was first established in 2000 to help foster and accelerate the growth of successful Canadian businesses and, after some uncertain times, it is now gathering momentum. A separate technology transfer office, MaRS Innovation, has also been established that, it is hoped, can be a world beater in its own right (see Turning good ideas into world beaters below). The location of the MaRS building in central Toronto is important, as it is just a stone's throw away from an existing cluster of universities and academic hospitals. MaRS has many links with other research-based organisations, including collaborations with three local universities, 10 academic teaching hospitals and the Ontario Institute for Cancer Research. MaRS occupies the Old Toronto general hospital, where insulin was first discovered by Best and Banting in 1921 and then developed for use in human trials. The 21st Century organisation can build on this heritage in patient-focused discovery and development. Formerly the head of venture capital firm Primaxis, Ilse Treurnicht is chief executive of MaRS Discovery District. She acknowledges the crisis in venture capital funding, and says Canada's sector has always had less access funds through this route than other countries. This is one of the drivers behind the search for a new approach. Treurnicht says the old models of building biotech and life sciences businesses have to be discarded, as they have failed to build companies with critical mass. She says MaRS' new 'Convergence Innovation' strategy of bringing science, capital and business together will pay off.

"We call our strategy 'Convergence Innovation' and what we are trying to do is move away from the old linear model of academics struggling in their spare time to build companies or entrepreneurs doing this in a very incremental way."It takes time and it has many risk points along the way. So using this Convergence centre model to create a much more dynamic organisation which can help accelerate good ideas towards the commercialisation." But she says Canada's geography and demographics are always going to be a challenge. "This is a very large country with a small population. If you think in terms of clusters and hub regions, Canada's business hubs are separated geographically, and there is not much in between in terms of people."That means we can't try to be a little United States, because we just won't show up on the radar. We have to take a different approach. We have to think about collaboration as our potential competitive advantage - that means using networks and associations to solve problems and build businesses."So as new opportunities emerge, we can take them to market faster and hopefully with a higher success rate." The centre currently accommodates numerous start up companies, as well as those providing legal and financial services to them. AstraZeneca and GlaxoSmithKline also have offices on site. In all, MaRS provides mentoring for over 200 different companies across Ontario, and runs courses on entrepreneurship and preparing products for market.

MaRS Innovation is honoured to announce its permanent Board of Directors, who brings together a remarkable and broad set of experiences and networks to support the development of this dynamic partnership of Toronto research institutions.  Designed to enhance the commercial output of Toronto’s world-leading research cluster, MaRS Innovation is positioned to make a significant contribution to Canada’s innovation economy and the quality of life for Canadians and others around the world.

upported by the Government of Canada through the Centres of Excellence in Research and Commercialization (CECR) program, and its member institutions, MaRS Innovation is focused on converting important discoveries into a new generation of products, services and high value jobs. The newly appointed Board of Directors, which includes academic and business leaders from across Canada and the United States, has the targeted expertise to guide MaRS Innovation to deliver on this critical mission.   MaRS Innovation represents a unique collaborative model, which aggregates the exceptional discovery pipeline of 14 leading Toronto academic institutions to build a diversified portfolio of assets, and harness the economic and job creation potential of the best opportunities for Toronto, Ontario and Canada.

“MaRS Innovation is privileged to announce a Board of Directors of this caliber and breadth of skill,” said Mary Jo Haddad, Chair of the MaRS Innovation Board and President and CEO of The Hospital for Sick Children. “The collective experience and guidance of these individuals will be critical to developing a collaborative, integrated and agile approach to this transformational organization that will move Canada into its next phase of economic development.”

Five cleantech companies receive support at the Cleantech Forum in Boston from Canadian incubation and innovation center MaRS.

Alternative Fuels was just one of a lineup of early-stage startups being supported by MaRS, a nonprofit innovation center in Toronto’s downtown Discovery District that connects entrepreneurs with business skills, networks and capital to stimulate innovation and grow Canadian companies.

This week’s forum marked the organization’s first foray into the cleantech sector, said MaRS Venture Group Associate Kevin Downing. Downing said he wanted to connect cleantech-related companies in the MaRS portfolio that were “investment ready” with the forum’s audience. “I don’t have a motive to push any one client over any other because they’re not paying me,” Downing said. Of the 1,300 MaRS portfolio companies, he said the cleantech sector has been its fastest growing segment and an expanding sector in country as well (see Canadian cleantech looks to the future and IPO drought? Cleantech companies flood Canadian markets). Since 2006, cleantech and environmental technology companies have made up 9 percent of MaRS' portfolio. MaRS currently has 350 active clients. The center isn’t government funded, but does receive some government support, he said. It has been funded through donations from the public and private sector. MaRS has the ability to provide some funding, around $40,000, to startups on a competitive basis. Other companies showcased at the forum through MaRS included NIMtech, Real Tech, Vicicog and Skymeter.

Look who just landed on MaRS

MaRS was known for just that – putting a collective roof over the heads of Canada's out-of-this-universe thinkers. Aside from hosting the unlikely duo of Arnold Schwarzenegger and Dalton McGuinty at a funding announcement two years ago, the centre seems enveloped in galactic silence.

corner of College and University

For Dr. John Evans, growing a strong biotechnology industry is much the same: cities must provide a nurturing environment where science and business can thrive together.

That's why Evans, former president of the University of Toronto and current chairman of Torstar Corp., is spearheading the $345-million Medical and Related Science initiative, or MaRS--a petri dish of sorts for commercializing science research. "A lot of intellectual property is being commercialized outside Canada," says Evans. "I think we've been slow in realizing just how important technology developments are to the economic future of the country. MaRS is an attempt to give this a kick into a higher gear." The centrepiece of the MaRS plan, which will officially launch May 12, is a 1.3-million-square-foot, five-building complex in downtown Toronto that will provide office and lab space for small and medium-size companies and incubators, including the not-for-profit Toronto Biotechnology Commercialization Centre. While Evans is reluctant to limit its scope, MaRS will generally focus on health-related technologies, from new drugs and genetic treatments to medical devices and imaging software. Branded a "convergence centre," it will also house a careful mix of support services: intellectual property lawyers, accountants, marketing experts, government funding organizations and venture capital financiers. Plus, start-ups will have access to all the latest equipment on site. For instance, MaRS is in talks with MDS Sciex to supply mass spectrometers, used in proteomics research.

But MaRS will be more than just a New Economy real estate development. Evans's intention is to funnel tenants' rent money into services--such as entrepreneurship seminars and angel-matching programs--that MaRS will offer to the broader biotech community. That's why MaRS's location is key: the centre will be built in the heart of what Toronto has dubbed the "Discovery District," a two-square-kilometre chunk of the downtown core, encompassing U of T and four major hospitals. From there, MaRS hopes to act as a network hub across Ontario, with links to research-intensive universities. "None of them," says Evans, "have the critical mass to put it all together on their own."

MaRS, a non-profit, collaborative entity of the university, provincial and federal governments and industry, which aims to turn these discoveries into commercial projects.

MaRS, a non-profit, collaborative entity of the university, provincial and federal governments and industry, which aims to turn these discoveries into commercial projects.

MaRS, a non-profit, collaborative entity of the university, provincial and federal governments and industry, which aims to turn these discoveries into commercial projects.

MobileMonday Toronto and MaRS are delighted to announce a partnership to develop and host a range of dynamic events for the city’s mobile industry professionals. MobileMonday at MaRS will offer thought leadership and critical industry perspectives – most recently from a senior manager at Research in Motion – while connecting top-tier professionals and boosting the profile of one of the fastest-growing sectors of communications technology.

“MaRS is a fantastic environment for sharing ideas and industry knowledge, two key building blocks of the MobileMonday community,” said Jim Brown and Alexander S. Bosika, co-founders of the MobileMonday Toronto chapter. “MaRS and its network of business advisors and capital providers are also of great benefit to many of our members who are developing business plans and seeking capital.”

For MaRS, the partnership is a natural fit with great potential to benefit the hundreds of start-up clients from across Ontario who are working hard to turn their innovative concepts into viable, thriving businesses, and come to MaRS for advice and connections to potential customers and investors. 

MaRS Innovation appoints president and CEO

A research commercialization leader from Israel, Dr. Raphael Hofstein, has been named president and CEO of the new MaRS Innovation initiative.

MI was created as a single, market-facing commercialization storefront for Toronto's university and health research institutions. Located in the MaRS Discovery District complex, with business development and administrative support from MaRS, MI will advance commercialization through industry partnerships, licensing and company creation. MaRS Innovation (MI) was founded in 2008 with $14.95 million in funding from the Government of Canada's Centres of Excellence for Commercialization and Research (CECR) Programme, matched by $10 million from the research partners. The MI partnership includes U of T, the 10 partner hospitals and health research institutes affiliated with the university, Ryerson University, the Ontario College of Art & Design, BioDisocovery Toronto, the Ontario Institute for Cancer Research and MaRS. Hofstein joins MaRS Innovation from his previous position as president and CEO of Hadasit Ltd., the technology transfer company of the Hadassah Medical Organization in Jerusalem.

Toronto’s MaRS Discovery District has combined the creative genius of science and technology with the drive of entrepreneurs and capital to create a marriage that will see more Canadian ideas commercialized in this country and for those efforts it has won the Canadian Urban Institute’s 2009 Creative City Award to be granted to MaRS on June 5 at the Urban Leadership Awards in Toronto.

“MaRS has found a creative way for science and business to collaborate rather than compete and to help Canada become a knowledge-based economy. This award recognizes them as a leader in stimulating the creative capacity of the city and advancing entrepreneurship, not only in science and technology but also in social ventures. 

Located in the Discovery District of Toronto, where billions of dollars of creative capital are created every year, the MaRS Centre first opened in 2005 in two new towers that bookend a heritage building that once housed the Toronto General Hospital. The three buildings, that total 700,000 sq. ft, house labs, companies of all sizes, business advisors and investors. Its professional services include hands-on advisory services, entrepreneurial programming and both structured and electronic networking. A second building phase of the MaRS Centre will add 750,000 sq ft and is planned to open in the next few years. “The underlining reason for creating MaRS is to capture the value of Canadian discoveries and to better commercialize these innovations at home in Canada,” said MaRS CEO Ilse Treurnicht. “Hub cities like Toronto are key drivers in shaping Canada’s innovation economy. MaRS works to strengthen the pull of that hub, acting as an accelerator and building the best ideas into companies that can compete on the world stage but are anchored here,” said Treurnicht.

MaRS aggregates the discovery pipelines of its member institutions, which include three universities, 10 academic teaching hospitals, and the Ontario Institute for Cancer Research.

MaRS is another good example. Located in the heart of downtown Toronto, the MaRS facility is less than a mile from five major teaching hospitals, the Ontario legislature, and the University of Toronto. More than two dozen research institutes and Toronto’s financial district are also nearby.

Consequently, MaRS is a vertical incubator, with a wide variety of companies and stages of development. That mix helps companies better understand the conditions that foster growth. MaRS is home to more than 65 organizations, including The Hospital for Sick Children, the Ontario Institute for Cancer Research, Merck Frosst Canada, the McEwen Centre for Regenerative Medicine, Celtic House Venture Partners, AIM Therapeutics, and AstraZeneca Canada.

Three technology research centres in Ontario Monday said they have agreed to work together to help the province compete more effectively against countries like India and China.

Communitech is working with the Ottawa Centre for Research and Innovation, an economic development corporation located in the nation's capital, and the MaRS Discovery District, a Toronto-based not-for-profit geared towards the commercialization of scientific and technological intellectual property.

MaRS originally stood for Medical and Research Sciences, but has since shied away from that label, said Ross Wallace, director of corporate strategy. The organization doesn't want to be pigeonholed as being just a life sciences or biotechnology outfit -- it lends equal weight to information communications and advanced manufacturing. MaRS may be Toronto-based, but its mandate is province-wide, said Wallace. By joining forces with organizations in other parts of Ontario, MaRS is more likely to fulfill that mandate, he said.

MaRS Innovation and The University of Toronto (U of T) are pleased to announce that they have entered into an agreement to collaboratively commercialize a novel sustained release formulation of nitric oxide (NO) for applications in wound healing, including diabetic ulcers. 

This wound healing technology is extremely exciting, making it an early commercialization opportunity that MaRS Innovation has identified as being a potential win for some 45 million diabetics globally,” said Dr. Rafi Hofstein, President and CEO of MaRS Innovation. 

disruptive technology that facilitates continued therapeutic release of NO over a two week period has been developed by Dr. Ping Lee, Professor at the Leslie Dan Faculty of Pharmacy and GlaxoSmithKline Chair in Pharmaceutics and Drug Delivery at U of T.

MaRS, a Toronto-based, not-for-profit incubation center, is leading a delegation of five cleantech ventures at this week’s Cleantech Forum XXIII in Boston. The companies – all clients of MaRS advisory services – will showcase their products for the cleantech CEOs, investors, scientists and policy makers attending the east coast forum. “While cleantech is a relatively new sector for MaRS advisory services, it is fast catching up with our other core strengths in information technologies and life sciences,” said Tom Rand, a cleantech entrepreneur, author and investor who leads MaRS’ cleantech practice. “MaRS is establishing itself as a major deal-flow engine in the cleantech sector, with an emphasis on early-stage companies.”

Alternative Fuels

Nimtech

MaRS Innovation and the Samuel Lunenfeld Research Institute of Mount Sinai Hospital are pleased to announce that they have entered into an agreement to collaboratively initiate commercialization of an umbilical cord stem cell technology for potential treatment in cardiovascular disease, diabetes and neurological disorders.

With the Toronto area identified as a world-leading cluster in stem cell research, we are extremely excited to have identified this technology as our first commercialization opportunity,” said Dr. Rafi Hofstein, President and CEO of MaRS Innovation.

MaRS Innovation, along with the inventors and Mount Sinai, will initially focus on the diabetes application for the technology, as research has demonstrated that these cells uniquely secrete insulin in response to glucose, thereby mimicking the “normal” physiological state.

MaRS places Israeli biotech veteran at helm

TORONTO – MaRS Innovation names Dr. Raphael Hofstein (pictured) as president and CEO. Dr. Hofstein comes to MaRS Innovation by way of Israel, where he was president and CEO of tech transfer company Hadasit Ltd.

“We are delighted to welcome Dr. Hofstein,” says Mary Jo Haddad, chair of MaRS Innovation, which is a subset of the Queen’s Park-sponsored innovation hub MaRS Discovery District.