I just read about this recently, really fascinating. It turns out the same group Foldit, is working in a similar format to develop better methods of teaching math and science in schools. And because these digital solutions are available in a virtual world, they are able to use tools like the internet to bring together gamers all over the world and really "hive mind" solutions to these scientific problems. In the article I read, the scientists talk about the flexibility the gamers have in working with 3D puzzles, and how it doesn't take long at all to solve these visual puzzles because it's just a game, and with a little bit of guidance it doesn't take long at all to catch the gamers up to speed with how proteins and enzymes 'should' fit together. Obviously there are some flexible rules, otherwise the computer would have figured it out earlier.
So I just thought this application was really fantastic, especially when networked to include potentially more of the public sphere. Makes me scientifically endlessly optimistic!