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The present study evaluated, using a well-controlled dehydration protocol, the effects of 24 h fluid deprivation (FD) on selected mood and physiological parameters. In the present cross-over study, twenty healthy women (age 25 (SE 0·78) years) participated in two randomised sessions: FD-induced dehydration v. a fully hydrated control condition. In the FD period, the last water intake was between 18.00 and 19.00 hours and no beverages were allowed until 18.00 hours on the next day (23-24 h). Water intake was only permitted at fixed periods during the control condition. Physiological parameters in the urine, blood and saliva (osmolality) as well as mood and sensations (headache and thirst) were compared across the experimental conditions. Safety was monitored throughout the study. The FD protocol was effective as indicated by a significant reduction in urine output. No clinical abnormalities of biological parameters or vital signs were observed, although heart rate was increased by FD. Increased urine specific gravity, darker urine colour and increased thirst were early markers of dehydration. Interestingly, dehydration also induced a significant increase in saliva osmolality at the end of the 24 h FD period but plasma osmolality remained unchanged. The significant effects of FD on mood included decreased alertness and increased sleepiness, fatigue and confusion. The most consistent effects of mild dehydration on mood are on sleep/wake parameters. Urine specific gravity appears to be the best physiological measure of hydration status in subjects with a normal level of activity; saliva osmolality is another reliable and noninvasive method for assessing hydration status.

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Karma KM-2500L Wheelchair is built with an ultra-lightweight aircraft-grade aluminum alloy frame with a standard seat width of: 16" and 18", it has a foldable frame with dual brake system and 20" flat-free rear wheels.It is Suitable for air travel or in limited space, senior care Ultra-light weight aircraft-grade aluminum alloy frame. Karma KM 2500 L Wheelchair Extended Armrest Karma KM-2500 L Wheelchair is amazingly light and compact transit wheelchair which is ideal for outings and travelers. It folds down to take up virtually no space in the boot of a car and weighs just over 11 kg making it easy for anyone to lift into a vehicle.Backrest folds-down for easy transportation Maximum user weight: 100Kg Aluminum frame Fixed armrest/fixed footrest Foldable frame via double cross bars Comfortable & durable upholstery Swing-away footplates. Key Features: Ultra-lightweight aircraft-grade aluminum alloy frame Standard seat width: 16" and 18" Foldable frame with dual brake system 20" flat-free rear wheels Attendant cable brake Detachable and washable cushion Maximum user weight: 100Kg One Year Warranty Karma Travel Wheelchair KM TV20 606 T-6 aircraft-grade aluminum-alloy frame provides incredible strength. Easy-to-fold in three seconds. Type: Travel Weight: 8.9kg Seat width: 39.5cm Tyre: PU front casters and rear wheels Capacity: 100kg Folded size: (L/W/h): 610mm x 350mm x710mm

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"A series of clinical studies have highlighted that the mental health is strongly linked to the physical health. If a person is not mentally healthy, h"

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Cancer is one of the world's deadliest terminal diseases accounting for one sixth of the world's total death toll every year according to the W.h.O. This high mortality rate is mostly due to late detection with the disease proving almost impossible to treat in its advanced stages. Although many of the symptoms of cancer can also be indications of other diseases, it is important to consult your doctor immediately you notice them for clinical examination and analysis.

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A Spigelian hernia is a type of ventral hernia that occurs when a weak spot or opening develops in the Spigelian fascia, a layer of tissue that separates two groups of abdominal muscles. These hernias are rare, accounting for only 0.12% to 2% of abdominal wall hernias. Let's explore more: https://www.southlakegeneralsurgery.com/spigelian-hernia-causes-and-treatments-explained/