Researchers at the University of California, Berkeley, have identified a gene that plays a critical regulatory role in the process of converting dietary carbohydrates to fat. In a new study, they disabled this gene in mice, which consequently had lower levels of body fat than their normal counterparts, despite being fed the equivalent of an all-you-can-eat pasta buffet.
The authors of the study, to be published in the March 20 issue of the journal Cell, say the gene, called DNA-PK, could potentially play a role in the prevention of obesity related to the over-consumption of high-carbohydrate foods, such as pasta, rice, soda and sugary snacks.
Scientists in Canada reviewing the research so far on links between different diets and heart disease found strong evidence that diets high in vegetables and nuts, and those that follow a Mediterranean pattern rich in fruit, vegetables and fish were strongly associated with lower heart disease risk than those that rely on food with a high glycemic index or high in trans-fatty acids. High glycemic index food includes rice, pasta and refined carbohydrates like white bread, and foods high in trans-fatty acids include fried foods, baked goods and snacks.