The pathobiology of diabetic complications: a unifying mechanism.
Brownlee M.
Diabetes. 2005 Jun;54(6):1615-25.
PMID: 15919781
doi: 10.2337/diabetes.54.6.1615
Egg consumption and risk of type 2 diabetes in men and women.
Djoussé L, Gaziano JM, Buring JE, Lee IM.
Diabetes Care. 2009 Feb;32(2):295-300. Epub 2008 Nov 18.
PMID: 19017774
DOI: 10.2337/dc08-1271
CONCLUSIONS-These data suggest that high levels of egg consumption (daily) are associated with an increased risk of type 2 diabetes in men and women. Confirmation of these findings in other populations is warranted.
TUESDAY, April 14 (HealthDay News) -- A particular type of stem cell transplantation using the patient's own cells led to short-term freedom from insulin injections in 20 of 23 patients newly diagnosed with type 1 diabetes participating in an experimental protocol in Brazil.
One patient even managed to go four years without needing outside sources of insulin, although the average was 31 months, said the authors of a report in the April 15 issue of the Journal of the American Medical Association, a themed issue on diabetes.
The patients also kept their blood sugar under control, which is key to preventing complications from diabetes. And, the authors stated, increased C-peptide levels indicated that the pancreas' beta cells were alive and well.
Lower serum creatinine is a new risk factor of type 2 diabetes: the Kansai healthcare study.
Harita N, Hayashi T, Sato KK, Nakamura Y, Yoneda T, Endo G, Kambe H.
Diabetes Care. 2009 Mar;32(3):424-6. Epub 2008 Dec 15.
PMID: 19074997
DOI: 10.2337/dc08-1265
Burning the candle at both ends during the working week could raise a person's risk of developing type 2 diabetes, New York researchers say.
People who slept fewer than six hours a night were more likely to develop a condition that precedes diabetes than those sleeping for longer, they found.
They said the study supported mounting evidence that cutting back on sleep can have a profound impact on health.
Cross-sectional association between fish consumption and albuminuria: the European Prospective Investigation of Cancer-Norfolk Study.
Lee CT, Adler AI, Forouhi NG, Luben R, Welch A, Khaw KT, Bingham S, Wareham NJ.
Am J Kidney Dis. 2008 Nov;52(5):876-86. Epub 2008 Jun 4.
PMID: 18534731
doi:10.1053/j.ajkd.2008.02.307
CONCLUSIONS: Greater fish intake was associated with a lower risk of macroalbuminuria in a self-defined diabetic population. These findings merit confirmation in prospective studies and intervention trials and suggest that fish intake may be beneficial for albuminuria in people with diabetes.
NEW YORK (Reuters Health) May 29 - Supplementation with coenzyme Q10 (CoQ10) improves endothelial dysfunction in patients with type 2 diabetes on statin therapy, according to results of a study reported in the May issue of Diabetes Care.
The vascular benefits of statins might be attenuated by inhibition of CoQ10 synthesis, Dr. Gerald T. Chew and colleagues from University of Western Australia, Perth, note in their report.
The vitamin K dependant protein osteocalcin may have a positive effect on reducing obesity and diabetes, suggests a new study with mice.\nResearchers writing in the journal Cells studied the effect bone cells have in energy regulation, and found that osteocalcin plays a key role in regulating insulin activity.
If wheat is so bad, what about all the other grains?
First of all, I demonize wheat because of its top-of-the-list role in triggering:
--Appetite--Wheat increases hunger dramatically
--Insulin
--Blood sugar--Wheat is worse than table sugar in triggering a rapid, large rise in blood sugar
--Triglycerides
--Small LDL particles--the number one cause for heart disease in the U.S.
--Reduced HDL
--Diabetes
--Autoimmune diseases--Most notably celiac disease and thyroiditis.
Most other "healthy, whole grains" aren't quite as bad. It's a matter of degree.
March 11, 2009 -- Low vitamin D levels greatly increase a teenager's risk of diabetes and heart disease, Johns Hopkins researchers find.
It is becoming clear that adults who get too little vitamin D are at higher risk for diabetes and heart disease. Now, it appears vitamin D levels also affect these risks earlier in life, say Johns Hopkins researchers Jared P. Reis, PhD, and colleagues.
Many health problems are accociated with diabetes complications. This chronic illness can cause high blood sugar levels, which in turn can lead to the damaging
Pittas AG, Lau J, Hu FB, Dawson-Hughes B. \nThe role of vitamin D and calcium in type 2 diabetes. A systematic review and meta-analysis.\nJ Clin Endocrinol Metab. 2007 Jun;92(6):2017-29. Epub 2007 Mar 27. Review.\nPMID: 17389701 [PubMed - indexed for MEDL
Inositols prevent and reverse endothelial dysfunction in diabetic rat and rabbit vasculature metabolically and by scavenging superoxide.
Nascimento NR, Lessa LM, Kerntopf MR, Sousa CM, Alves RS, Queiroz MG, Price J, Heimark DB, Larner J, Du X, Brownlee M, Gow A, Davis C, Fonteles MC.
Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):218-23. Epub 2005 Dec 22.
PMID: 16373499
doi: 10.1073/pnas.0509779103
Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study.
onsson T, Granfeldt Y, Ahren B, Branell UC, Palsson G, Hansson A, Soderstrom M, Lindeberg S.
Cardiovasc Diabetol. 2009 Jul 16;8(1):35. [Epub ahead of print]
PMID: 19604407
doi:10.1186/1475-2840-8-35
Benfotiamine (rINN, or S-benzoylthiamine O-monophoshate) is a synthetic S-acyl derivative of thiamine (vitamine B1). After absorption, benfotiamine can be dephosphorylated by cells bearing an ecto-alkaline phosphatase to the lipid-soluble S-benzoylthiamine.
The primary use of this antioxidant is as an "anti-AGE" supplement.[3] In a trial, benfotiamine lowered AGE by 40%.[4] However, in Germany doctors have been known to combine benfotiamine with pyridoxine hydrochloride and use it to treat patients with nerve damage and nerve pain such as sciatica.
At high doses, benfotiamine was shown to be effective for the treatment of diabetic retinopathy, neuropathy, and nephropathy. I
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