GAVNet Collaborative Curation

Breeders have been working to develop new Miscanthus hybrids for years, but the clonal crop's sterility, complex genome, and long time to maturity make conventional breeding difficult. In a new study, University of Illinois researchers mine the crop's vast genomic potential in an effort to speed up the breeding process and maximize its most desirable traits.

Most recent macro trends - cloud compute, social, mobile, crypto, AI - that have reshaped the technology landscape are rooted in new technical capabilities or pushing the frontier of product form factors. Another shock to the system is emerging today, driven not by the underlying technology, but by an evolution in customer buying behavior. For shorthand, we think of this trend as "growth+sales": the bottom-up growth motion eventually layered with top-down sales.

In the flagship article, The ENCODE Project Consortium et al.5 provide a bird's-eye view of the updated encyclopedia, which contains newly added data sets from 6,000 experiments, performed on around 1,300 samples. By integrating these data sets, the consortium has created an online registry of candidate CREs. Most are classified as promoters or enhancers - CREs respectively located at or some distance from the genomic site at which transcription of a gene begins. The consortium tracked the activity of each candidate CRE, along with the proteins that bind to it in many different samples from various tissues. They used chromatin-looping data to link enhancers to genes that they might regulate. This online registry marks a true milestone, turning an overwhelming amount of genomic information into a searchable, filterable and retrievable encyclopedia of DNA elements, which is freely accessible at https://screen.encodeproject.org.

As social distancing became norm and law in the early days of the Covid-19 pandemic, people turned to video teleconferencing to meet with friends and family, attend religious services, and go on dates. Zoom work accounts became a conduit for maintaining nonwork social ties, and as people came to depend on this enterprise tool, Zoom's stock valuation soared.1 The pandemic has widened the sphere of life dependent on such market technologies, heightening existing questions around the political, legal, and economic governance of these companies. How should the fabric of social life, especially as it is rewoven by the pandemic, relate to the private ownership of telecommunications?

Aside from filtering, warming, and humidifying the air you breathe, the nose is your first line of defense against allergens and pathogens. The mucus and cilia inside are designed to block these outside invaders from going farther down the respiratory tract and making you sick. And NO, which is what the sinuses release when you breathe through your nose, is a vasodilator, meaning it relaxes the blood vessels and lowers blood pressure.