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"With each interaction, Alexa is training to hear better, to interpret more precisely, to trigger actions that map to the user's commands more accurately, and to build a more complete model of their preferences, habits and desires. What is required to make this possible? Put simply: each small moment of convenience - be it answering a question, turning on a light, or playing a song - requires a vast planetary network, fueled by the extraction of non-renewable materials, labor, and data. The scale of resources required is many magnitudes greater than the energy and labor it would take a human to operate a household appliance or flick a switch. A full accounting for these costs is almost impossible, but it is increasingly important that we grasp the scale and scope if we are to understand and govern the technical infrastructures that thread through our lives. III The Salar, the world's largest flat surface, is located in southwest Bolivia at an altitude of 3,656 meters above sea level. It is a high plateau, covered by a few meters of salt crust which are exceptionally rich in lithium, containing 50% to 70% of the world's lithium reserves. 4 The Salar, alongside the neighboring Atacama regions in Chile and Argentina, are major sites for lithium extraction. This soft, silvery metal is currently used to power mobile connected devices, as a crucial material used for the production of lithium-Ion batteries. It is known as 'grey gold.' Smartphone batteries, for example, usually have less than eight grams of this material. 5 Each Tesla car needs approximately seven kilograms of lithium for its battery pack. 6 All these batteries have a limited lifespan, and once consumed they are thrown away as waste. Amazon reminds users that they cannot open up and repair their Echo, because this will void the warranty. The Amazon Echo is wall-powered, and also has a mobile battery base. This also has a limited lifespan and then must be thrown away as waste. According to the Ay

"In his influential paper How Complex Systems Fail, Richard Cook shares 18 brilliant observations on the nature of failure in complex systems. Part 1 of this article was my attempt to translate the first nine of his observations into the context of web systems, i.e., the distributed systems behind modern web applications. In this second and final part, I'm going to complete the picture and cover the other half of Cook's paper. So let's get started with observation #10!"

"This is a wonderfully short and easy to read paper looking at how complex systems fail - it's written by a Doctor (MD) in the context of systems of patient care, but that makes it all the more fun to translate the lessons into complex IT systems, including their human operator components. The paper consists of 18 observations. Here are some of my favourites…."

Recent major surveys show that reductions in genomic complexity - including the loss of key genes - have successfully shaped the evolution of life throughout history.

By exchanging resources, the members of a microbial community can survive in environments where individual species cannot. Despite the abundance of such syntrophy, little is known about its evolutionary origin. The predominant hypothesis is that syntrophy arises when originally independent organisms in the same community become interdependent by accumulating mutations. In this view, syntrophy arises when organisms co-evolve. In sharp contrast we find that different metabolism can interact syntrophically without a shared evolutionary history. We show that syntrophy is an inherent and emergent property of the complex chemical reaction networks that constitute metabolism.

The synthesis of structurally complex organic molecules is the first task in the discovery of functional compounds needed for new technologies, including those in medicine and flexible electronics. Starting with relatively simple, purchasable reactants, the process involves sequences of chemical reactions in which the complexity of the molecules produced gradually increases with each step towards the final target. The sequences can be linear, or convergent (different parts of the target molecule are made in separate sequences and then joined together). To ensure that large amounts of the final product are prepared, each synthetic step must be high-yielding and reproducible, and must generate few side products.

The damage we are not attending to is the deeper nature of the crisis-the collapse of multiple coupled complex systems. Societies the world over are experiencing what might be called the first complexity crisis in history. We should not have been surprised that a random mutation of a virus in a far-off city in China could lead in just a few short months to the crash of financial markets worldwide, the end of football in Spain, a shortage of flour in the United Kingdom, the bankruptcy of Hertz and Niemann-Marcus in the United States, the collapse of travel, and to so much more.

For decades, scientists have been using a classical experimental search task-which involves placing a single rat in a complex maze to search for a reward-to deepen understanding of navigation, memory, and learning. However, rats are highly social animals that build and live in complex burrow systems in nature. Yet very little is known about how they explore as a group. In the new study, researchers from institutes in Germany and Hungary turned the classical experimental search task into the first experimental study on rodent group search behavior in a confined maze.

COVID-19 is a wicked problem for policy makers internationally as the complexity of the pandemic transcends health, environment, social and economic boundaries. Many countries are focusing on two key responses, namely virus containment and financial measures, but fail to recognise other aspects. The systems approach, however, enables policy makers to design the most effective strategies and reduce the unintended consequences. To achieve fundamental change, it is imperative to firstly identify the "right" interventions (leverage points) and implement additional measures to reduce negative consequences. To do so, a preliminary causal loop diagram of the COVID-19 pandemic was designed to explore its influence on socio-economic systems. In order to transcend the "wait and see" approach, and create an adaptive and resilient system, governments need to consider "deep" leverage points that can be realistically maintained over the long-term and cause a fundamental change, rather than focusing on "shallow" leverage points that are relatively easy to implement but do not result in significant systemic change

For protein molecules that contribute to metabolism, interactions with other components of their metabolic pathway can be crucial. Scientists at the Max Planck Institute for Developmental Biology in Tübingen have now investigated a natural enzyme complex that comprises 10 enzymes with five distinct activities. They found that the molecular architecture is surprisingly compact, yet offers individual enzymes maximum free moving space, which opens up novel perspectives for drug discovery. The scientists have published their results in Nature Chemical Biology.