GAVNet Collaborative Curation

Wheat is a staple food across all parts of the world and is one of the most widely grown and consumed crops7. As the human population continues to grow, wheat production must increase by more than 50% over current levels by 2050 to meet demand7. Efforts to increase wheat production may be aided by comprehensive genomic resources from global breeding programs to identify within-species allelic diversity and determine the best allele combinations to produce superior cultivars2,8.

An exercise in pure mathematics has led to a wide-ranging theory that unites Plato with geophysics.

Artificial intelligence (AI) has solved one of biology's grand challenges: predicting how proteins curl up from a linear chain of amino acids into 3D shapes that allow them to carry out life's tasks. Today, leading structural biologists and organizers of a biennial protein folding competition announced the achievement by researchers at DeepMind, a U.K.-based AI company. They say the DeepMind method will have far-reaching effects, among them dramatically speeding the creation of new medications.

Researchers .... have made reported some exciting findings relating to metal-organic frameworks (MOFs), a class of porous materials, which could benefit a wide range of important gas separation processes.

The "Perturb-Seq" method, published in the journal Science, is an efficient way to identify potential biological mechanisms underlying autism spectrum disorder, which is an important first step toward developing treatments for the complex disease. The method is also broadly applicable to other organs, enabling scientists to better understand a wide range of disease and normal processes.

ot long ago, Joe Davis, the "artist-scientist" in George Church's genetics lab at Harvard Medical School, was in Brittany, France. The region is known for thousand-year-old salterns that produce fleur de sel, or flower of salt-salt that forms as seawater evaporates. Davis was there sampling these brightly colored ponds with a microscope, and found in the shallow waters an abundance of diverse halophiles, organisms that can grow in and tolerate saline conditions. "I wondered what happens to these organisms," he said. "The salt is evaporating, the water's gone. The organisms aren't just going to disappear. Where are they?"

The emergence of three lethal coronaviruses in <20 years and the urgency of the COVID-19 pandemic have prompted efforts to develop new therapeutic strategies, including by repurposing existing agents. After performing a comparative analysis of the three pathogenic human coronaviruses severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1), SARS-CoV-2, and Middle East respiratory syndrome coronavirus (MERS-CoV), we identified shared biology and host-directed drug targets to prioritize therapeutics with potential for rapid deployment against current and future coronavirus outbreaks.

Similar levels of income inequality may coexist with completely different distributions of capital and labor incomes. This column introduces a new measure of compositional inequality, allowing the authors to distinguish between different capitalist societies. The analysis suggests that Latin America and India are rigid 'class-based' societies, whereas in most of Western European and North American economies (as well as in Japan and China), the split between capitalists and workers is less sharp and inequality is moderate or low. Nordic countries are 'class-based' yet fairly equal. Taiwan and Slovakia are closest to classless and low inequality societies.

The result highlights a fundamental tension: Either the rules of quantum mechanics don't always apply, or at least one basic assumption about reality must be wrong.

"Spooky action at a distance," Einstein's summation of quantum physics, has been a criticism of quantum mechanics since the field emerged. So far, descriptions of entangled particles to explain their apparently faster-than-light responses, and even explanations for the phase shifts induced by an electromagnetic field in regions where it is zero-the "Aharonov-Bohm" effect-have mostly addressed these concerns. However, recent theoretical and experimental demonstrations of a "counterfactual" quantum communication protocol have proved difficult to explain in terms of physical cause and effect. In this kind of quantum communication, observers on either side of a "transmission channel" exchange information without any particle passing between them-spooky indeed.