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"In the last decade Open Science principles, such as Open Access, study preregistration, use of preprints, making available data and code, and open peer review, have been successfully advocated for and are being slowly adopted in many different research communities. In response to the COVID-19 pandemic many publishers and researchers have sped up their adoption of some of these Open Science practices, sometimes embracing them fully and sometimes partially or in a sub-optimal manner. In this article, we express concerns about the violation of some of the Open Science principles and its potential impact on the quality of research output. We provide evidence of the misuses of these principles at different stages of the scientific process. We call for a wider adoption of Open Science practices in the hope that this work will encourage a broader endorsement of Open Science principles and serve as a reminder that science should always be a rigorous process, reliable and transparent, especially in the context of a pandemic where research findings are being translated into practice even more rapidly"

Immediate action is required to halt the COVID-19 Pandemic and treat those it has affected. It is a practical and moral imperative that every tool we have at our disposal be applied to develop and deploy technologies on a massive scale without impediment. We therefore pledge to make our intellectual property available free of charge for use in ending the COVID-19 pandemic and minimizing the impact of the disease. We will implement this pledge through a license that details the terms and conditions under which our intellectual property is made available.

Emission scientifique, "Comment ça marche ?", diffusée sur la chaîne française TF1 en 1994. Publiée sur la plateforme YouTube le 19 février 2013. Durée de la séquence : 1h01min Produit avec le concours de SVS et Intel Corp Intel Copyright 1994 Licence : Licence YouTube standard

"Government Technology Policy, Social Value, and National Competitiveness Harvard Business School Strategy Unit Working Paper No. 19-103"

Our grins are not as simple as they seem. There are a myriad different ways to smile - and some of them can conceal some less than happy feelings.

With this, we now know the exact mRNA contents of the BNT162b2 vaccine, and for most parts we understand why they are there: The CAP to make sure the RNA looks like regular mRNA A known successful and optimized 5' untranslated region (UTR) A codon optimized signal peptide to send the Spike protein to the right place (copied 100% from the original virus) A codon optimized version of the original spike, with two 'Proline' substitutions to make sure the protein appears in the right form A known successful and optimized 3' untranslated region A slightly mysterious poly-A tail with an unexplained 'linker' in there The codon optimization adds a lot of G and C to the mRNA. Meanwhile, using Ψ (1-methyl-3'-pseudouridylyl) instead of U helps evade our immune system, so the mRNA stays around long enough so we can actually help train the immune system.