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anonymous

ScienceDirect - International Journal of Pharmaceutics : Dendrimer toxicity: Let's meet... - 9 views

www.sciencedirect.com/...S0378517310002991

dendrimers biomaterials toxicity

shared by anonymous on 14 Oct 11 - No Cached
  • anonymous on 14 Oct 11
     
    Dendrimers are well-defined, versatile polymeric architecture with properties resembling biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine system because of its derivatisable branched architecture and flexibility in modifying it in numerous ways. Dendritic scaffold has been found to be suitable carrier for a variety of drugs including anticancer, anti-viral, anti-bacterial, antitubercular etc., with capacity to improve solubility and bioavailability of poorly soluble drugs. In spite of extensive applicability in pharmaceutical field, the use of dendrimers in biological system is constrained because of inherent toxicity associated with them. This toxicity is attributed to the interaction of surface cationic charge of dendrimers with negatively charged biological membranes in vivo. Interaction of dendrimers with biological membranes results in membrane disruption via nanohole formation, membrane thinning and erosion.
anonymous

WWF - WildFinder - 28 views

gis.wwfus.org/wildfinder

wildfinder animals extinct endangered habitats

shared by anonymous on 06 Jan 10 - Cached
  • anonymous on 06 Jan 10
     
    Known worldwide by its panda logo, World Wildlife Fund (WWF) leads international efforts to protect endangered species and their habitats and address global threats such as toxic pollution, over-fishing and climate change. Learn about job and employment opportunities and scan WWF's publications.
Mr. Mohan

Iraq Holding First Election since U.S. Troop Withdrawal | United States Institute of Peace - 5 views

www.usip.org/...t-election-us-troop-withdrawal

shared by Mr. Mohan on 23 Apr 13 - No Cached
  • s itself a triumph of sorts
    • Mr. Mohan
      Mr. Mohan on 23 Apr 13
       
      Why is this a triumph and is this a sign of hope?
  • The process does, however, face some challenges.
    • Mr. Mohan
      Mr. Mohan on 23 Apr 13
       
      Be alert for the challenges
  • three provinces forming the Kurdistan Region of Iraq (KRI) hold their elections separately.
    • Mr. Mohan
      Mr. Mohan on 23 Apr 13
       
      Why are the Kurdish regions different?
  • ...7 more annotations...
  • Kirkuk
  • parties representing the ethnic and religious diversity of the province have not been able to agree to hold elections
    • Mr. Mohan
      Mr. Mohan on 23 Apr 13
       
      Is this a positive/negative?
  • Baghdad decided to postpone elections in the Sunni-majority western provinces, Anbar and Nineveh, for security reasons
    • Mr. Mohan
      Mr. Mohan on 23 Apr 13
       
      What do the two areas not holding elections have in common?
  • harbinger
  • In terms of a national identity, it might imply that certain provinces are less important than others
  • Given the toxic political environment, the rivalries and electoral history in Iraq, the integrity of elections will come into question by some.
  • Political and other differences are normal, but it is important that they are dealt with peacefully through a process of dialogue and problem-solving
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