1992 Study to determine if there was a significant association between an intrapartum amniotic fluid index (AFI) < or = 5.0 cm and neonatal acidosis (umbilical arterial pH < 7.20 or metabolic acidosis [umbilical arterial pH < 7.20 and base deficit > 10 mEq/L]).
PubMed abstract: Neonatal depression and birth asphyxia in the low birthweight neonate. In 392 low birthweight neonates, acidosis as evident from umbilical artery pH 7.1 or less was strongly associated with Apgar score 6 or lower at 1 minute. However, most cases that were depressed (Apgar score 6 or lower at 1 minute) were not acidotic. Neonatal depression was most strongly and directly correlated with gestational age. Neonatal depression and birth asphyxia are distinct entiti
PubMed Study Abstract: Ten indicators available during the first two hours of life, such as clinical criteria of neonatal distress and postnatal arterial blood gases, were compared
with the neonatal neurological course in sixty full term newborns with significant birth asphyxia in order to test their value for the diagnosis and the short-term prognosis of severe birth asphyxia. Birth asphyxia was defined as severe when it was followed by symptoms of moderate or severe post-asphyxial encephalopathy.
PubMed.gov Study Abstract - Study to identify neonatal risk factors for cerebral palsy among very preterm babies and in particular the associations independent of the coexistence of antenatal and intrapartum factors.
PubMed.gov Abstract - 2008 Case Western Reserve University- Dept of Pediatrics study on trends in the rates of cerebral palsy associated with neonatal intensive care of preterm children, neonatal morbidity and rates of cerebral palsy associated low birth weight and low gestation infants.
NIH PubMed Abstract of Belgium study to assess the intra- and interobserver reliability and reproducibility of goniometry and visual estimation of ankle joint range of motion measurements in children with spastic cerebral palsy.
Statistical analysis showed a high reliability for intra- and interobserver measurements (r>0.75), between visual estimation and goniometry (correlation coefficient, r>0.967; concordance coefficient, r>0.957). Both visual estimation and goniometry ankle range-of-motion measurements are reliable and reproducible in spastic cerebral palsy children if a strict but simple protocol is applied.
NIH PubMed Abstract - Testing range of motion in cerebral palsy. Objective of study was to To propose a standardized test of joint range of motion in paediatric patients with cerebral palsy, based on the opinion of a cerebral palsy specialist group (physicians, physiotherapists and surgeons) and literature review. Study concluded that a standardized testing of lower-limb-joint range of motion will allow for better communication between clinicians and will facilitate the development of a database. Care should be taken in the interpretation of the joint range-of-motion test results and realized only after reliability analysis of the test, especially interobserver reliability. A further step would be to develop an outpatient booklet for cerebral palsy that shows growth and weight curves, joint range-of-motion curves and curves of the principal radiographic measurements during growth.
PubMed Abstract of 2009 study conducted by School of Medicine, Bosnia and Herzegovina assessing importance of early diagnosis and intervention in relation to cerebral palsy
NIH, and Eunice Kennedy Shriver National Institute of Child Health and Human Development - Review and trial to determine whether magnesium sulfate administered to women at risk of preterm delivery may reduce the risk of cerebral palsy in their children
PubMed Abstract of study to determine the prevalence and nature of feeding difficulties and oral motor dysfunction among a representative sample of 49 children with cerebral
palsy (12 to 72 months of age).
PubMed Abstract of study to evaluate the effect of Selective Dorsal Rhizotomy (SRD) Surgery on functional abilities in a well-defined group of ambulatory children with Spastic Diplegia
National Library of Medicine - National Institute of Health - PubMed Article Abstract: Floppy infant syndrome - Review - On long-term follow up, cerebral palsy and mental retardation turn out to be the 2 most common causes of FIS. This review focuses on neuromuscular causes of FIS. With the advent of molecular diagnosis, a few conditions can be diagnosed by DNA analysis of the peripheral lymphocytes (myotonic dystrophy, spinal muscular atrophy); however, for the most part, electrodiagnostic studies and muscle biopsy remain as essential diagnostic tools for FIS.
