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Hypertonia Treatment Information at National Institute of Neurological Disorders and Stroke NINDS

Completed study classified types of Hypertonia in patients with Cerebral Palsy and determine if the classifications are reasonable in relation to the functional task of walking. Hypertonia is an abnormal increase in muscle tension. It is a common symptom of Cerebral Palsy that can lead to loss of function and deformity. This study may help scientists improve evaluation criteria for hypertonia and, ultimately, treatment results.

Planned study to evaluate the impact of a possible new treatment for hypertonia, contributing to the motor disability in children with cerebral palsy (CP)."

Study will examine the effectiveness of botulinum toxin as treatment for a variety of movement disorders. The goals of the study are to refine the technique of treatment to provide the best results, to improve the understanding of how botulinum toxin works on movement disorders, and find other conditions that may be treatable with botulinum toxin.In addition, researchers also plan to study the possible use of botulinum toxin F alone and in combination with botulinum toxin A in patients who do not respond to botulinum A toxin treatment.

PubMed Abstract of study to evaluate the effect of Selective Dorsal Rhizotomy (SRD) Surgery on functional abilities in a well-defined group of ambulatory children with Spastic Diplegia

Clinical trial being conducted by Eunice Kennedy Shriver NationalInstitute of Child Health and Human Development NICHD to examine botulinum toxin (BOTOX, or BTX) for the treatment of muscle twitches and spasticity associated with cerebral palsy in children. Botulinum toxin is a naturally occurring bacterial toxin (botulinum toxin) that inactivates certain parts of muscles.

PEDIATRICS artice of study to document the effects of botulinum toxin A injections into the gastrocnemius muscles in children with spastic diplegia. Outcomes are evaluated across all 5 domains of the National Centers for Medical and Rehabilitation Research domains of medical rehabilitation.

MD Movement Disorder Virtual Library - Healthcare professional's source for movement disorder news, resources and educational activities. Not-for-profit organization that has been educating and informing the movement disorder community for over a decade. WE MOVE believes that increased knowledge and understanding promote timely, accurate diagnosis and up-to-date treatment, resulting in a better quality of life for individuals affected by movement disorders.

Journal of the American Medical Assocation JAMA Abstract regarding Intrathecal Baclofen for Spasticity in Cerebral Palsy

PubMed Abstract of observations that concluded that significant improvements were noted when comparing the two-electrode system with the new multiple level electrode. Marked to moderately improved patients increased from 57 to 84% in Cerebral Palsy, from 44 to 82% in dystonia, from 53 to 75% in torticollis and from 53 to 80% in Cystonia, from 53 to 80% in posttraumatic neurologic conditions

Baclofen Efficacy and Safety Trials - Pediatric Pharmacokinetic and Pharmacodynamic Study of Oral Baclofen for the Treatment of Spasticity Associated with Cerebral Palsy (BEST-PK/PD)