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Lee Vander Loop

Birth Trauma: eMedicine Pediatrics: Birth Trauma - 0 views

emedicine.medscape.com/...980112-overview

eMedicine Birth Trauma mechanical forces risks of birth injury risks of cerebral palsy birth trauma cerebral palsy risks emedicine

shared by Lee Vander Loop on 20 Jul 10 - Cached
  • Lee Vander Loop on 20 Jul 10
     
    eMedicine - Birth Trauma - Birth Injury risks and information
Lee Vander Loop

Whole-Body Cooling for Birth Asphyxia in Term Infants - 1 views

clinicaltrials.gov/...NCT00005772

whole body cooling and asphyxia neonatal brain injury prevention birth injury prevention clinical trials cooling

shared by Lee Vander Loop on 27 May 10 - Cached
  • Lee Vander Loop on 27 May 10
     
    Acute birth asphyxia is a cause of death and neurological injury. At present, there is no proven treatment; however, studies in animals suggest that brain cooling may protect against brain injury. This large multicenter trial will randomize term infants with a history of problems at delivery and signs of depression to total body cooling or standard care.
Lee Vander Loop

Recombinant Erythropoietin for Neuroprotection in Very Preterm Infants - China Medical ... - 0 views

clinicaltrials.gov/...NCT00910234

clinical trial clinical trials research study erythropoietin neuroprotection

shared by Lee Vander Loop on 27 May 10 - Cached
  • Lee Vander Loop on 27 May 10
     
    A recent study using high-dose rhEpo (3000 U rhEpo/kg body weight at birth) for neuroprotection in very preterm infants revealed that no signs of adverse effects of early high-dose rhEpo treatment in very preterm infants were identified. Contrary to this, a recent study in PVL of a rat model revealed that using a low dose rhEpo (50-100 U/kg) was effective in the treatment of brain damage induced by hypoxia-ischemia and did not affect normal oligodendrocyte maturity. On this basis, the researchers intent to investigate (1) whether low-dose rhEpo (100 U/kg) or high-dose rhEpo (3,000 U/kg) given to very preterm infants (gestation age < 32 weeks) immediately after birth and subsequently during the first 2 days is safe and possesses neuroprotective properties;(2) whether there are gender differences in response to the hypoxia-ischemic insult and EPO treatment; (3)the pharmacokinetics of low dose and high dose rhEPO.
Lee Vander Loop

MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(H... - 1 views

clinicaltrials.gov/...NCT01128673

hypoxic Ischemic encephalopathy prevent brain injury birth asphyxia brain temperature MRI imaging of cooling effects clinical trial clinical trials HIE

shared by Lee Vander Loop on 27 May 10 - Cached
  • Lee Vander Loop on 27 May 10
     
    Hundreds of babies in the world are being treated with brain cooling to prevent brain injury after they lose oxygen at birth. This study will use the newly developed information from the magnet resonance image to determine the actual temperature of the brain. This will enable researchers to determine if the brain is being uniformly cooled and if techniques that provide cooling need to be changed to improve the injury prevention from cooling
Lee Vander Loop

Progesterone (17OHP) for Prolongation of Pregnancy in Women With Preterm Rupture of the... - 0 views

clinicaltrials.gov/...NCT01119963

preterm rupture of membranes clinical trials clinical trial 17OHP PROM 17PinProm progesterone research study

shared by Lee Vander Loop on 27 May 10 - Cached
  • Lee Vander Loop on 27 May 10
     
    Study is to determine if a weekly dose of 17P (Progesterone) given to women with preterm rupture of the membranes will: increase the probability of continuing the pregnancy until a favorable gestational age.Increase the interval between randomization and delivery. Decrease neonatal morbidity.
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