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Using simple robots to simulate genetic evolution over hundreds of generations, Swiss scientists provide quantitative proof of kin selection and shed light on one of the most enduring puzzles in biology: Why do most social animals, including humans, go out of their way to help each other? In next week's issue of the online, open access journal PLoS Biology, EPFL robotics professor Dario Floreano teams up with University of Lausanne biologist Laurent Keller to weigh in on the oft-debated question of the evolution of altruism genes.

For more than 20 years, theoretical mathematical models have predicted that a delay built into a negative feedback system is at the heart of the molecular mechanism that governs circadian clocks in mammalian cells. Now, the first experimental proof of this theory has been provided by an international research team led by molecular biologists and information scientists from the RIKEN Center for Developmental Biology in Kobe. The demonstration of the feedback delay should lead to a better understanding of how cellular clocks function, and therefore how mammals adjust to the regular daily and seasonal changes in their environment. The work could also open the way to the development of treatments for circadian disorders, such as seasonal affective disorder, jet lag and even bipolar disorder.

The largest continuous expanse of forest in the world, found in the country's cold northern regions - is undergoing an accelerating large-scale shift in vegetation types as a result of globally and regionally warming climate. That in turn is creating an even warmer climate in the region, according to a new study published in the journal Global Change Biology and highlighted in the April issue of Nature Climate Change.

Collectively, malaria, TB & HIV/AIDS cause more than five million deaths per year - nearly the entire population of the state of Washington - and represent one of the world's major public health challenges as we move into the second decade of the 21st century. In the May 26, 2011, edition of scientific journal Nature, Seattle BioMed Director Alan Aderem, Ph.D., along with Rino Rappuoli, Ph.D., Global Head of Vaccines Research for Novartis Vaccines & Diagnostics, discuss recent advances in vaccine development, along with new tools including systems biology and structure-based antigen design that could lead to a deeper understanding of mechanisms of protection. This, in turn, will illuminate the path to rational vaccine development to lift the burden of the world's most devastating infectious diseases.

Bats in North America are under a two-pronged attack but they are not the only victim - so is the U.S. economy. Gary McCracken, head of the Department of Ecology and Evolutionary Biology at the University of Tennessee, Knoxville, analyzed the economic impact of the loss of bats in North America in agriculture and found it to be in the $3.7 to $53 billion a year range.

Instinct and the annual increase of daylight hours have long been thought to be the triggers for birds to begin their spring migration. Scientists at the Smithsonian Conservation Biology Institute, however, have found that that may not be the case. Researchers have focused on how warming trends in temperate breeding areas disrupt the sensitive ecology of migratory birds. This new research shows that changes in rainfall on the tropical wintering grounds could be equally disruptive. The team's findings are published in scientific journal Proceedings of the Royal Society B, today, March 30.

In an unprecedented collaborative analysis published in the journal PLoS Biology, scientists from 49 nations demonstrated that the ability of reef fish systems to produce goods and services to humanity increases rapidly with the number of species. However, growing human populations hamper the ability of reefs to function normally, and counterintuitively, the most diverse reef fish systems suffer the greatest impairments from stressors triggered by human populations. The study documented that the extent of this distress is widespread and likely to worsen because 75% of the world's reefs are near human settlements and because around 82% of the tropical countries with coral reefs could double their human populations within the next 50 to 100 years.

A new study from the Karolinska Institute and Stockholm School of Economics shows that the brain has built-in mechanisms that trigger an automatic reaction to someone who refuses to share. In the study publishing next week in the online open access journal PLoS Biology, the subjects' sense of justice was challenged in a two-player monetary fairness game, and their brain activity was simultaneously measured using functional magnetic resonance imaging (fMRI). When bidders made unfair suggestions as to how to share the money, they were often punished by their partners even if it cost them. This reaction to unfairness could be reduced by targeting one specific brain region, the amygdala.

The diversity of the biological world is astounding. How do new species arise? In the traditional view, most speciation events occur under special circumstances, when a physical barrier arises and divides a population into groups that can no longer interbreed. The populations diverge genetically and eventually can't interbreed even if the barrier disappears.

The environmental concern is great when considering the role of toxic contaminants in the plant-soil relationship. Understanding plant's absorption and accumulation of these contaminants from the soil would be incredibly beneficial.