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In the growing global battle against substandard and counterfeit medicines, the Promoting the Quality of Medicines (PQM) program has launched a new, public database of medicines collected and analyzed in collaboration with stakeholders from countries in Africa, South America and Southeast Asia. Free of charge and available to anyone with access to the internet, the Medicines Quality Database (MQDB) includes information on the quality of medicines collected from a variety of sources. To date, more than 8700 records of tested samples collected from Ghana, Laos, Vietnam, Cambodia, the Philippines, Thailand, Peru, Guyana and Colombia have been entered into the database.

If internal and international migrants comprised a nation, it would be the third most populous country in the world, just after China and India. Thus, there can be little doubt that population mobility is among the leading policy issues of the 21st century. However, policies to protect migrants and global health have so far been hampered by inadequate policy attention and poor international coordination. This is the conclusion of a new article in PLoS Medicine arguing that current policy-making on migration and health has been conducted within sector silos, which frequently have different goals. Yet, population mobility is wholly compatible with health-promoting strategies for migrants if decision-makers coordinate across borders and policy sectors, say the authors, who are also serving as guest editors of a new series in PLoS Medicine on migration & health that launches this week.

Mount Sinai School of Medicine researchers have found that climate change may lead to more asthma-related health problems in children, and more emergency room (ER) visits in the next decade.

A class of engineered nanoparticles -- gold-centered spheres smaller than viruses -- has been shown safe when administered by two alternative routes in a mouse study led by investigators at the Stanford University School of Medicine. This marks the first step up the ladder of toxicology studies that, within a year and a half, could yield to human trials of the tiny agents for detection of colorectal and possibly other cancers.

Since 2010, insurance companies had been turned essentially into public utilities with the feds setting strict minimum benefits requirements. The health reform bill also limited the administrative costs of insurers, which has ended up basically guaranteeing their profits. With competition all but outlawed, the increasingly consolidated insurance industry has had very little incentive to pay for new treatment regimens outside those specified by government standard-setting agencies. Federal government health agencies have been reluctant to authorize newer treatments because they often lead to higher insurance premiums that then must be subsidized by higher taxes. The seen aspect of health care reform is that it has had some success in providing more Americans with access to vintage 2010 medical therapies. The unseen aspect is that more people are suffering from and dying of diseases that might well have been cured had the Obama version of health care reform never been enacted. As a result of health care reform, Americans forfeited 2020 medicine in favor of more equal access to 2010 treatments.

Researchers at Mount Sinai School of Medicine have found that patients with Alzheimer's disease have lower glucose utilization in the brain than those with normal cognitive function, and that those decreased levels may be detectable approximately 20 years prior to the first symptoms of Alzheimer's disease. This new finding could lead to the development of novel therapies to prevent the eventual onset of Alzheimer's. The study is published online in the journal Translational Neuroscience.

Invisibility appears to be the next possible advance in the use of Terahertz radiation in medicine, security, and communications.

Collectively, malaria, TB & HIV/AIDS cause more than five million deaths per year - nearly the entire population of the state of Washington - and represent one of the world's major public health challenges as we move into the second decade of the 21st century. In the May 26, 2011, edition of scientific journal Nature, Seattle BioMed Director Alan Aderem, Ph.D., along with Rino Rappuoli, Ph.D., Global Head of Vaccines Research for Novartis Vaccines & Diagnostics, discuss recent advances in vaccine development, along with new tools including systems biology and structure-based antigen design that could lead to a deeper understanding of mechanisms of protection. This, in turn, will illuminate the path to rational vaccine development to lift the burden of the world's most devastating infectious diseases.

Meditation produces powerful pain-relieving effects in the brain, according to new research published in the April 6 edition of the Journal of Neuroscience.

Medical ethicist Harvey Fineberg shows us three paths forward for the ever-evolving human species: to stop evolving completely, to evolve naturally - or to control the next steps of human evolution, using genetic modification, to make ourselves smarter, faster, better. Neo-evolution is within our grasp. What will we do with it?

A "bionic" leg designed for people who have lost a lower leg is undergoing clinical trials sponsored by the US Army. The researchers hope the leg will be able to learn the patient's nerve signal patterns and be able to move in response to the patient's own muscles and nerves.