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suwhitte

Welcome to CDC's DES Update Homepage - 0 views

shared by suwhitte on 16 May 10 - Cached
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    Background on diethylstilbesterol, a synthetic estrogen, that has caused transgenerational effects.
suwhitte

TEDX - The Endocrine Disruption Exchange - 0 views

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    Site started by Theo Colburn, author of "Our Stolen Future."
suwhitte

Environmental Agents: Endocrine Disruptors - 0 views

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    site maintained by the National Institute of Environmental Health Sciences.
suwhitte

Environmental Health Perspectives - 0 views

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    Environmental Health Perspectives (EHP) is a monthly journal of peer-reviewed research and news published by the U.S. National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services. EHP's mission is to serve as a forum for the discussion of the interrelationships between the environment and human health by publishing in a balanced and objective manner the best peer-reviewed research and most current and credible news of the field. With an impact factor of 6.12, EHP is the top monthly journal in public, environmental, and occupational health and the second-ranked monthly journal in environmental sciences. The environmental health sciences include many fields of study and increasingly comprise a multidisciplinary research area. EHP publishes articles from a wide range of scientific disciplines encompassing basic research; epidemiologic studies; risk assessment; relevant ethical, legal, social, environmental justice, and policy topics; longitudinal human studies; in vitro and in vivo animal research with a clear relationship to human health; and environmental medicine case reports. Because children are uniquely sensitive to their environments, EHP devotes a research section specifically to issues surrounding children's environmental health. Search current issue and archives for journal articles related to your topic.
suwhitte

ehormone website - Tulane University - 0 views

shared by suwhitte on 14 May 10 - Cached
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    Excellent website with current information on a variety of EED-related topics. Includes some learning modules and links to other resources.
Matthew Ragan

Estrogen Receptor Interacting with DNA - 0 views

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    Nuclear hormone receptor proteins form a class of ligand activated proteins that, when bound to specific sequences of DNA serve as on-off switches for transcription within the cell nucleus. These switches control the development and differentiation of skin, bone and behavioral centers in the brain, as well as the continual regulation of reproductive tissues.
suwhitte

Environment and health: 6. Endocrine disruption and potential human health implications... - 0 views

shared by suwhitte on 20 May 10 - Cached
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    link to a pdf of a review article on endocrine disruptors and human health. A nice overview of the field.
Anna McLean

Reproductive Toxins and Alligator Abnormalities at Lake Apopka, Florida - 0 views

  • it has been shown that many of the environmental chemicals found in alligator plasma or eggs bind the alligator estrogen and/or progesterone receptors in vitro
  • Guillette et al. ( 1 ) suggested that the reproductive failure at Lake Apopka could have been related to general agricultural pollution and to a spill from a nearby pesticide manufacturing facility. From 1957 to 1981, the facility (Tower Chemical Co.) manufactured and stored both chlorinated and organophosphate insecticides as well as a copper-salt-based fungicide at a site 1.5 miles from Lake Apopka. Wastewater from the manufacturing process was discharged into an unlined pond, and chemicals were burned or buried on site. During a heavy rain in 1980, the percolation pond overflowed and acidic wastewater discharged into a marsh that drains into Lake Apopka. DDT and other chemicals contaminated the lake during this extensive spill.
  • ecause of the endocrine-disruptive potential of DDT's degradation products DDE and DDD, they have been the prime suspects in the reproductive abnormalities of the alligators
  • ...4 more annotations...
  • The route of exposure for the alligators living in this environment might have occurred through both oral and dermal exposure
  • he testicular abnormalities in alligators from Lake Apopka are similar to those in pesticide workers exposed to DBCP in that the seminiferous tubules are the affected target tissues.
    • Anna McLean
       
      Similar abnormalities act as evidence for the negative effects of DBCP. Evidence such as this help to support the cause, and disable individuals from referring to the alligators' issues as coincidence. Or that they have nothing to do with chemical spills, pesticides, and other pollutants.
  • given the levels found in the remaining pond, it is almost certain that DBCP entered Lake Apopka during the 1980 spill.
  • The findings discussed above indicate a complex exposure scenario in which the etiology of the reproductive failure cannot be reconstructed with certainty due to the historic nature of the event
    • Anna McLean
       
      Emphasizes the difficultly scientists have in proving the causes of the observed problems in many species, such as the Lake Apopka alligators.
cmccleery1

Endocrine disruption in fish - Google Books - 0 views

shared by cmccleery1 on 24 May 10 - Cached
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    This is a google preview of a book which is about how the endocrine system is obstructed nad affected in fish
suwhitte

BP's Corexit Increases Uptake of Endocrine Disruptors in Fish - What Will It Do to Peop... - 0 views

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    Report by an M.D. describing the ED effects of the dispersant used to "manage" the BP oil spill. Includes link to article on how PAH uptake by fish is increased when exposed to the dispersant (Corexit - give me a break on the name!).
suwhitte

The endocrine system and endocrine disruptors | The Canary Report - 0 views

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    An exchange site for those concerned about chemical sensitivity. Many links to interesting articles.
suwhitte

Endocrine Disruption Prevention Act of 2009 - 0 views

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    A letter from the American Fisheries Society to Obama asking him to support the Endocrine Disruption Prevention Act of 2009.
Anna McLean

ScienceDirect - Brain, Behavior, and Immunity : The potential influence of maternal st... - 0 views

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    Brandon, This may also be of interest to you.
Liz Richardson

Global assessment of the state-of-the-science of endocrine disruptors - 0 views

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    This is just the index, but the WHO has attempted to pinpoint which hormone compounds are most effective EEDs, and which hormones are most often mimicked. Discusses EED effects on wildlife as well as humans. Criteria for assessment of endocrine disruptors proposed for future studies.
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