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Researchers in the US and UK say they have invented a new microscopy technique for imaging live tissue with unprecedented speed and resolution. The technique involves using the tiny tip of an atomic force microscope to tap on a living cell and analysing the resulting vibrations to reveal the mechanical properties of cell tissue. The team says that the technique could have widespread applications in medicine. However, another expert in the field suggests that the group has not demonstrated the superiority of the technique to those already available.

These guys from caltech work on a minituarized, automated microscope. Could be interesting for any type of human space exploration.

Electron microscope studies reveal that the electron bombardment leads to polymerization of the outer layer of some insect larva's skin and protects them from dehydration. Artificial method to create this effect tested as well. Allows observation of living animals under electron microscope! Question: can the insects still breath after they are back in air? :-S

Physicists in Germany have developed the first-ever "nano-ear" capable of detecting sound on microscopic length scales with an estimated sensitivity that is six orders of magnitude below the threshold of human hearing.

one can see that you are in bed and bored :-)

Recharge in seconds and efficiently store power for weeks between charges. Added bonus is the cheap and abundant components needed. One of the applications they foresee is to attach such a super-capacitor to the back of solar panels to store the power and discharge this during the night

very nice indeed - is this already at a stage where we should have a closer look at it? what you think? With experience in growing carbon nanostructures, Pint's group decided to try to coat the porous silicon surface with carbon. "We had no idea what would happen," said Pint. "Typically, researchers grow graphene from silicon-carbide materials at temperatures in excess of 1400 degrees Celsius. But at lower temperatures - 600 to 700 degrees Celsius - we certainly didn't expect graphene-like material growth." When the researchers pulled the porous silicon out of the furnace, they found that it had turned from orange to purple or black. When they inspected it under a powerful scanning electron microscope they found that it looked nearly identical to the original material but it was coated by a layer of graphene a few nanometers thick. When the researchers tested the coated material they found that it had chemically stabilized the silicon surface. When they used it to make supercapacitors, they found that the graphene coating improved energy densities by over two orders of magnitude compared to those made from uncoated porous silicon and significantly better than commercial supercapacitors. Transmission electron microscope image of the surface of porous silicon coated with graphene. The coating consists of a thin layer of 5-10 layers of graphene which filled pores with diameters less than 2-3 nanometers and so did not alter the nanoscale architecture of the underlying silicon. (Cary Pint / Vanderbilt) The graphene layer acts as an atomically thin protective coating. Pint and his group argue that this approach isn't limited to graphene. "The ability to engineer surfaces with atomically thin layers of materials combined with the control achieved in designing porous materials opens opportunities for a number of different applications beyond energy storage," he said.

In this article the authors describe an improvement of their optical microscope techniques for which some of the received a Nobel prize in the past. They achieve resolutions far beyond the optical diffraction limit which is supposed to limit detail resolution due to quantum-mechanical effects. Their techniques include structured illuminiation (producing interference patterns), switchable fluorescent markers as well as multi-frame super resolution enhancement. Authors are able to take a single image in about 0.3 seconds which allows the study of protein processes in the cell: http://spon.de/vgTb7 . Although it is hard to imagine the application of many of these techniques for telescopes (except for super resolution), I am wondering if any of this could help building telescopes with increased optical power or reduced weight. Any ideas..?

Useful for space exploration, e.g. subsurface water reservoirs such as Europa or Enceladus? Nanoengineers at the University of California, San Diego used an innovative 3-D printing technology they developed to manufacture multipurpose fish-shaped microrobots -- called microfish -- that swim around efficiently in liquids, are chemically powered by hydrogen peroxide and magnetically controlled.

Here is the tractor beam I mentioned from fridays science coffee. At the moment its used for microscopic particles only. This could be looked into to see if it could be scaled up to deflect particles in space

A new 3D microscope with amazing capabilities.

Bacterial wires explain enigmatic electric currents in the seabed: Each one of these 'cable bacteria' contains a bundle of insulated wires that conduct an electric current from one end to the other. Cable bacteria explain electric currents in the seabed Electricity and seawater are usually a bad mix.

WOW!!!! don't want to even imagine what we do to these with the trailing fishing boats that sweep through sea beds with large masses .... "Our experiments showed that the electric connections in the seabed must be solid structures built by bacteria," says PhD student Christian Pfeffer, Aarhus University. He could interrupt the electric currents by pulling a thin wire horizontally through the seafloor. Just as when an excavator cuts our electric cables. In microscopes, scientists found a hitherto unknown type of long, multi-cellular bacteria that was always present when scientists measured the electric currents. "The incredible idea that these bacteria should be electric cables really fell into place when, inside the bacteria, we saw wire-like strings enclosed by a membrane," says Nils Risgaard-Petersen, Aarhus University. Kilometers of living cables The bacterium is one hundred times thinner than a hair and the whole bacterium functions as an electric cable with a number of insulated wires within it. Quite similar to the electric cables we know from our daily lives. "Such unique insulated biological wires seem simple but with incredible complexity at nanoscale," says PhD student Jie Song, Aarhus University, who used nanotools to map the electrical properties of the cable bacteria. In an undisturbed seabed more than tens of thousands kilometers cable bacteria live under a single square meter seabed. The ability to conduct an electric current gives cable bacteria such large benefits that it conquers much of the energy from decomposition processes in the seabed. Unlike all other known forms of life, cable bacteria maintain an efficient combustion down in the oxygen-free part of the seabed. It only requires that one end of the individual reaches the oxygen which the seawater provides to the top millimeters of the seabed. The combustion is a transfer of the electrons of the food to oxygen which the bacterial inner wires manage over centimeter-long distances. However, s

Perhaps when you think of bacterial communities you think of a flask full of rapidly dividing E. coli. But in non-lab conditions, bacteria grow in complex, heterogeneous communities composed of diverse microscopic organisms. In these communities, bacteria need a means to communicate with their kin, and they do this through a language known as quorum sensing (QS), where bugs secrete and detect factors that tell them whether they're surrounded by kin (and if so, how many there are).

Awesome! Origami finally got useful! :-D

Basically quantum entanglement, or more accurately the dispersal and expansion of mixed quantum states, results in an apparent flow of time. Quantum information leaks out and the result is the move from a pure state (hot coffee) to a mixed state (cooled down) in which equilibrium is reached. Theoretically it is possible to get back to a pure state (coffee spontaneously heating up) but this statistical unlikelihood gives the appereance of irreversibility and hence a flow o time. I think an interesting question is then: how much useful work can you extract from this system? (http://arxiv.org/abs/1302.2811) It should for macroscopic thermodynamic systems lead to the Carnot cycle, but on smaller scales it might be possible to formulate a more general expression. Anybody interested to look into it? Anna, Jo? :)

What you propose is called Maxwell's demon: http://en.wikipedia.org/wiki/Maxwell%27s_demon Unfortunately (or maybe fortunately) thermodynamics is VERY robust. I guess if you really only want to harness AND USE the energy in a microscopic system you might have some chance of beating Carnot. But any way of transferring harvested energy to a macroscopic system seems to be limited by it (AFAIK).

"We have made optical systems at the microscopic scale that amplify light and produce ultra-narrowband spectral output," explained J. Gary Eden, a professor of electrical and computer engineering (ECE) at Illinois. "These new optical amplifiers are well-suited for routing optical power on a chip containing both electronic and optical components.

"With a resolution of 297.500 x 87.500 pixel (26 gigapixel) the picture is the largest in the world. (stand December 2009)" Daring statement... I'm not quite sure, but I'd quess microscopic images used in medicine can easily reach terapixels... What a waste of pixels anyway... they weren't able to find a bit more interesing city?

yeah... like Leiden !

is this the breaktrough that we were waiting for?

That depends on what application you are thinking of. For circuit board electronics this will allow integration of micro sized supercapacitors to provide operational power. They will have to be fed by external batteries still, but the close proximity allows for better tailored power demands. They also propose tapping into thermal/mechanical energy to charge the supercaps. In the end, they can provide significant specific power (W/kg) but you still need to upscale the production to cover large areas to also gain high specific energy (Wh/kg). This breakthough is for micro sized applications, not for replacement of large scale energy storage (electric vehicles, satellites) going up to kWh. That said, I know of several studies in supercaps at ESA, but they are still qualifying current relatively old commercial solutions.

Great engineering feat from Capasso's idea - an integrated flat lens electrically controlled enabling dynamic beam steering. Reconfigurabilility is the aim. The lens can be used microscope systems, holographic and projection imaging, LIDAR and laser printing. Besides working now on the mid-IR, visible light is the target.