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In Crystal Pharmatech, instead of one-size-fit-all platforms or "super-placebo" or quick and rough "fit-for-purpose" formulation approaches in early development, we apply a "First-Time-Right" strategy for formulation development to accelerate your molecule to First in Human (FIH) studies and onward to commercialization at a cost-effective and time-saving way.

We guide our customers into making smarter formulation choices. Ultimately, this reduces the risk of clinical failure and ensures your product reaches the clinic rapidly via the most efficient route.

Founded in 2007, AVT (Shanghai) Pharmaceutical Tech Co., Ltd. (hereinafter referred to as AVT) specializes in providing high quality excipients and services for advanced injections. The company's products range from high quality traditional injection grade phospholipid excipients applied for liposomes and fat emulsions, such as natural phospholipids, HSPC, DSPE-PEG2000, CHO, etc.; as well as protective agents and buffers salts used in vaccines, antibody proteins, antibody-conjugated drugs and other biological formulations, such as trehalose, sucrose, sucrose potassium octasulfate, etc.

Most small molecule drugs are formulated as oral solid dosage (OSD) forms, such as tablets or capsules. OSD has been an important part of the global pharmaceutical market. The formulation team of Crystal Pharmatech is formed by technical experts with considerable experience in formulation development and dosage form optimization. We design and develop the solid dosage form and process tailor-made for your molecule based on a deep understanding of the material properties of API and to meet its intended clinical needs.

Amorphous Solid Dispersions pharmaceutical amorphous solid dispersions have been shown to alter the properties of an API, including solubility, dissolution, and bioavailability. A variety of polymers or additives are available, and screening is needed to find possible miscible dispersions that will have the properties needed for development. Our service including: The amorphous spray dried dispersion will then be used in simple formulations for early development (such as suspensions, drug in capsules, or preliminary formulations) or formulated into a drug product (such as tablets or capsules) for late-stage development and marketed products.

Bioavailability Enhancement for Insoluble Compounds & PROTAC & Oral Peptides Recent statistics indicate that approximately 40% of currently marketed drugs and nearly 90% of candidates in R&D pipeline belong to Biopharmaceutics Classification System (BCS) II or IV poorly water-soluble drugs. Consequently, enhancing drug solubility and improving bioavailability are pressing challenges in the realm of new drug development. Widely employed methods for solubility enhancement include:

In the preceding article, we discussed the application of hot-melt extrusion technology in developing amorphous solid dispersions (ASD) for pharmaceutical formulations. The process involves dispersing a solution through a spray dryer, where it meets hot gas, quickly evaporates, and forms amorphous solids. Spray drying techniques are extensively employed in developing formulations for drugs with low solubility, largely due to their well-established scalability from small-scale experiments to large-scale commercial production, aligning with Good Manufacturing Practice (GMP) standards. Table 1 in the article provides examples of various drugs that have been commercially produced using spray drying technology to prepare amorphous solid dispersions.

OCCUPATIONAL HEALTH & SAFETY MANAGEMENT SYSTEM ISO 45001 Certification ISO 45001:2018 CERTIFICATION IN UAE | OCCUPATIONAL HEALTH & SAFETY CERTIFICATION The ISO 45001:2018 Certification Standard replaces OHSAS 18001:2007, with a focus on creating safer workplaces. It aims to prevent serious accidents, reduce workplace injuries, and minimize lost workdays. According to the International Labor Organization, there are 2.78 million fatal workplace accidents annually, along with 374 million smaller work-related injuries. ISO 45001 Certification in the UAE integrates well with other ISO Quality Management Standards like ISO 9001 and ISO 14001. Organizations previously certified with OHSAS 18001:2007 are transitioning to ISO 45001:2018, following guidelines set by the International Accreditation Forum. BENEFITS OF ISO 45001 CERTIFICATION IN UAE - Enhances reputation - Demonstrates commitment to employee safety and property protection - Ensures compliance with Health and Safety Legislation - Improves efficiency, reducing downtime - Controls costs by minimizing incidents - Reduces insurance premiums - Fosters a safety culture - Enhances standing with regulatory authorities - Promotes ethical behavior among employees - Increases awareness and positive perception in society ISO 45001 CERTIFICATION COST IN UAE The cost for ISO 45001 certification in UAE is presented as a fixed fee, regardless of organization size or industry. We offer a flat rate to ensure transparency and avoid surprises. Simply provide your details, and we'll offer a reasonable quote for your ISO 45001 Certification needs. BEGINNING YOUR ISO 45001:2018 OH&S CERTIFICATION JOURNEY Considering ISO 45001:2018 Occupational Health & Safety Management System (OH&S) Certification in UAE? Here are essential steps to start your journey: 1. Current State Analysis: Analyze your current Occupational Health and Safety situation, considering internal and external factors. 2. Establish System Scope and Goals: Defi

Highlights of API Form and solid state services Serving over 1000 clients worldwide Supported solid form screening, crystallization, and preclinical formulation development of over 2,000 new drug molecules The world's leading technology supports the understandingof molecule and formulation with a high-end platform High-quality service, a culture of confidentiality, and fast turnaround with cost-effective pricing Customized solution for your molecule, spanning the entire drug lifecycle API Form and solid state chemistry services Solid Form Screening and Selection Solid form is a general term that refers to both crystalline and amorphous materials. The solid form will impact active pharmaceutical ingredient (API) development properties such as solubility, dissolution rate, stability, hygroscopicity, and bioavailability.

Founded in 2007, AVT (Shanghai) Pharmaceutical Tech Co., Ltd. (hereinafter referred to as AVT) specializes in providing high quality excipients and services for advanced injections. The company's products range from high quality traditional injection grade phospholipid excipients applied for liposomes and fat emulsions, such as natural phospholipids, HSPC, DSPE-PEG2000, CHO, etc.; as well as protective agents and buffers salts used in vaccines, antibody proteins, antibody-conjugated drugs and other biological formulations, such as trehalose, sucrose, sucrose potassium octasulfate, etc.

Founded in 2007, AVT (Shanghai) Pharmaceutical Tech Co., Ltd. (hereinafter referred to as AVT) specializes in providing high quality excipients and services for advanced injections. The company's products range from high quality traditional injection grade phospholipid excipients applied for liposomes and fat emulsions, such as natural phospholipids, HSPC, DSPE-PEG2000, CHO, etc.; as well as protective agents and buffers salts used in vaccines, antibody proteins, antibody-conjugated drugs and other biological formulations, such as trehalose, sucrose, sucrose potassium octasulfate, etc.

It exhibits strong inhibition effect on melanogenesis, reduces dark spots and age spots, fights photoaging by interfering with inflammatory cytokines, such as IL-6, and reverse ROS production to achieve free radical scavenging purpose. 3-O-ethyl ascorbic acid is effectively a newer form of Vitamin C that offers a better overall performance. It is water soluble with excellent heat and photostability profile. Best of all, it is highly stable and easy to formulate.

when formulated correctly and protected from degrading, peptides can have the same function. Choose Gihi Chemicals pea protein manufacturer for competitive wholesale pea protein.

Apex is a well-known certification organization that serves both government and non-government sectors. We offer accredited certification, training, auditing, and research & development (R&D) services. We're accredited by the Emirates International Accreditation Centre (EIAC), which significantly boosts the credibility of our certification process. Accreditation from EIAC ensures that our assessment and certification procedures meet established standards and best practices. This gives organizations and stakeholders confidence in the certifications we issue. At Apex, we prioritize safety and compliance, demonstrating our dedication to ensuring that certified organizations adhere to industry-specific regulations, standards, and legal requirements.

casno. : CAS 18543-68-5 Amino acid-based organic fertilizer 80% powder is soy-based products, with high free amino acid 80% can be applied in the formulation. It is natural from plant nitrogen making it ideal for environmentally sound horticultural and agricultural practices.

MONSA® DLS 90 is widely used in the preparation of hand lotion (liquid), foam cleansing cream, foam cleanser, foam shaving cream, as well as a clean and non-smooth foam shower gel and pearl shampoo. When applied, it is added to the formulation system with pH=5.0-7.0, and it can not be directly compounded directly with the raw material with pH>7.

MONSA® sodium isostearoyl lactate is an excellent multi-functional agent. It's a good moisturizer for skin and hair, which is suitable for formulating shampoo, shower gel, facial cleanser, cream and lotion products.

Twobrosrepellent snake away spray - the natural and effective solution for keeping snakes away from your property! Made with 100% natural peppermint and garlic essential oil ingredients, this pet and child-pet safe snake repellent is perfect for both indoor and outdoor use. Its long-lasting mist is perfectly formulated to prevent serious reptile outbreaks and get rid of unwanted snakes in a natural and organic way. With fresh and energizing scents, our natural essential oil spray creates a strong smell and taste to deter snakes naturally, without causing any harm to people, pets or plants. Protect your property and prevent new pests with Twobrosrepellent's snake killer spray today!