Group items tagged

Global Pharmaceutical Glass Packaging Market Report by Product (Glass Vials, Ampoules, and Cartridges), by Application (Generic Drugs, Branded Drugs, and Biological Drugs) and by Region - Global Forecast to 2023.

Bioavailability Enhancement for Insoluble Compounds & PROTAC & Oral Peptides Recent statistics indicate that approximately 40% of currently marketed drugs and nearly 90% of candidates in R&D pipeline belong to Biopharmaceutics Classification System (BCS) II or IV poorly water-soluble drugs. Consequently, enhancing drug solubility and improving bioavailability are pressing challenges in the realm of new drug development. Widely employed methods for solubility enhancement include:

The number of people with diabetes rose from 151 million in 2000 to 463 million in 2019; by 2045 this number will rise to 700 million. 1 in 5 of the people who are above 65 years old have diabetes, 1 in 2 people (232 million) with diabetes were undiagnosed, and diabetes caused 4.2 million deaths. Diabetes caused at least USD760 billion dollars in health expenditure in 2019 - 10% of total spending on adults. More than 1.1 million children and adolescents are living with type 1 diabetes, and 374 million people are at increased risk of developing type 2 diabetes.

In 2024, cannabis users will get more protection from their employers when it comes to smoking outside of work. In the meantime, here's a refresher on who can use weed - and when and where - in California. Can my employer penalize me for cannabis use? California recently passed a new cannabis bill, protecting employees from weed bias, but it will be a while before it goes into effect. Called AB 2188, it bans employers from discriminating against employees based on their use of weed off the job and away from the workplace. This includes the hiring, employment and termination processes. The law's exceptions include people working in the construction and building industry or positions that require federal background clearances. And while it protects off-duty smoking, employers will still have the right to fire or suspend employees for using weed or being high while at work. Although the bill was signed by Gov. Gavin Newsom in September, it won't be carried out until January 2024. Weed might be legal, but not for everyone Recreational cannabis use has been legal since 2016, but only for those 21 years old and over. Those under 18 who are caught with weed will be subject to drug education or counseling and community service. People who are older than 18 but under 21, will be fined up to $100. But minors can apply for a medical marijuana identification card to get weed for medicinal purposes. In California, children under 18 years old can apply as a patient if they are emancipated or have declared self-sufficiency status, according to the state's Department of Health. If they do not have this status, then the county will contact the individual's parent or legal guardian. The legal limit of weed How much cannabis you can have on hand is limited in California, according to the state's health and safety code. You'll be penalized if you possess more than 28.5 grams of weed, or more than eight grams of concentrated cannabis - essentially about one ounce.

HACCP Certification | Hazard Analysis Critical Control Points Hazard Analysis Critical Control Points (HACCP) is officially recognized by food and drug administrative authorities as pivotal control points for managing elements harmful to food. HACCP Certification integrates hazard analysis (HA) and critical control points (CCP). HA involves identifying and analyzing hazard elements and their structure. On the other hand, HACCP Certification determines sanitation control points to manage major hazards identified from material supply, manufacturing, processing, preservation, and distribution up to end-user consumption. In essence, HACCP Certification represents a scientific food sanitation control system designed to ensure the safety and hygiene of food products through an effective and proactive hygiene control system. It serves as a management system focused on food safety, involving the analysis and control of hazard elements from biological, chemical, and physical perspectives. HACCP encompasses the entire life cycle of a food product, from material supply and food manufacturing to distribution and consumption. HACCP Certification - Benefits - Sanitation control - Production of food in a sanitary manner - Focus on sanitation effort and effective food control - Economic control of food products (reduction of defective product and customer complaints) - Reliability in food products - Safe and sanitary distribution of food products - Choice of sanitary food products through public certification - Prevention of food hygiene problems - Export advantage - Advantageous inspection process - Indication of HACCP mark HACCP Certification with APEX SC APEX SC is globally recognized for its expertise in HACCP Certification. Our cost-effective packages ensure accessibility for organizations across all industry sectors. Our simplified consulting methods help clients seamlessly incorporate essential requirements. HACCP has been successfully implemented in numerous compani

In Crystal Pharmatech, instead of one-size-fit-all platforms or "super-placebo" or quick and rough "fit-for-purpose" formulation approaches in early development, we apply a "First-Time-Right" strategy for formulation development to accelerate your molecule to First in Human (FIH) studies and onward to commercialization at a cost-effective and time-saving way.

Amorphous Solid Dispersions pharmaceutical amorphous solid dispersions have been shown to alter the properties of an API, including solubility, dissolution, and bioavailability. A variety of polymers or additives are available, and screening is needed to find possible miscible dispersions that will have the properties needed for development. Our service including: The amorphous spray dried dispersion will then be used in simple formulations for early development (such as suspensions, drug in capsules, or preliminary formulations) or formulated into a drug product (such as tablets or capsules) for late-stage development and marketed products.

History of solid state nmr Nuclear Magnetic Resonance (NMR) Spectroscopy is a ubiquitous analytical technique utilized across a wide range of disciplines. In the pharmaceutical industry, NMR is used in drug discovery and development to verify structures, to monitor reactions, and to characterize the solid phase structure of APIs and drug products.

Highlights of API Form and solid state services Serving over 1000 clients worldwide Supported solid form screening, crystallization, and preclinical formulation development of over 2,000 new drug molecules The world's leading technology supports the understandingof molecule and formulation with a high-end platform High-quality service, a culture of confidentiality, and fast turnaround with cost-effective pricing Customized solution for your molecule, spanning the entire drug lifecycle API Form and solid state chemistry services Solid Form Screening and Selection Solid form is a general term that refers to both crystalline and amorphous materials. The solid form will impact active pharmaceutical ingredient (API) development properties such as solubility, dissolution rate, stability, hygroscopicity, and bioavailability.

In the preceding article, we discussed the application of hot-melt extrusion technology in developing amorphous solid dispersions (ASD) for pharmaceutical formulations. The process involves dispersing a solution through a spray dryer, where it meets hot gas, quickly evaporates, and forms amorphous solids. Spray drying techniques are extensively employed in developing formulations for drugs with low solubility, largely due to their well-established scalability from small-scale experiments to large-scale commercial production, aligning with Good Manufacturing Practice (GMP) standards. Table 1 in the article provides examples of various drugs that have been commercially produced using spray drying technology to prepare amorphous solid dispersions.

" Hunan Afen Vending Machine Co., Ltd. is a high-technology company,which is specialized in the developing, production and marketing of related products in the field of self-service technology. As a leading vending machine system solutions provider in China, with its advanced technical ability and huge manufacturing capacity,is the best supplier and partner in self-service market .AFEN with plant 22,000 square meters, more than 50 million fixed assets. In 2017, the company expanded the plant 60,000 square meters, becoming one of the largest vending machine production base in the world. AFEN has the industry's leading independent core technology and sustainable R&D capabilities, according to different demands of customers to design and provide the best and professional self-service retail solutions, be widely used in schools, highways, airports, railway stations, shopping malls, hospitals,enterprises etc.,can sell food, stationery, books, toys, clothing, drugs and family planning supplies, Lunch box, fresh fruit juice etc., and support coins, notes, WeChat, Alipay, IC card,QR code payment etc.,with GPRS remote management control system.AFEN vending machines have been used in 50 countries and areas.AFEN determined to become the outstanding and professional vending machine companies and self-service retail industry leader."

It can be used in medical drugs and health-care products, mainly in repairing joint diseases, protecting joints and has analgesic effect when company by chondroitin sulfate. It also has supportive therapeutic efficacy in rheumatoid arthritis, heart disease, pneumonia and fractures, as well as multiple beneficial physiological effect in absorption of free radicals and anti-aging, losing weight and regulating internal secretion as discovered in recent years.

Founded in 2007, AVT (Shanghai) Pharmaceutical Tech Co., Ltd. (hereinafter referred to as AVT) specializes in providing high quality excipients and services for advanced injections. The company's products range from high quality traditional injection grade phospholipid excipients applied for liposomes and fat emulsions, such as natural phospholipids, HSPC, DSPE-PEG2000, CHO, etc.; as well as protective agents and buffers salts used in vaccines, antibody proteins, antibody-conjugated drugs and other biological formulations, such as trehalose, sucrose, sucrose potassium octasulfate, etc.

Founded in 2007, AVT (Shanghai) Pharmaceutical Tech Co., Ltd. (hereinafter referred to as AVT) specializes in providing high quality excipients and services for advanced injections. The company's products range from high quality traditional injection grade phospholipid excipients applied for liposomes and fat emulsions, such as natural phospholipids, HSPC, DSPE-PEG2000, CHO, etc.; as well as protective agents and buffers salts used in vaccines, antibody proteins, antibody-conjugated drugs and other biological formulations, such as trehalose, sucrose, sucrose potassium octasulfate, etc.

Founded in 2007, AVT (Shanghai) Pharmaceutical Tech Co., Ltd. (hereinafter referred to as AVT) specializes in providing high quality excipients and services for advanced injections. The company's products range from high quality traditional injection grade phospholipid excipients applied for liposomes and fat emulsions, such as natural phospholipids, HSPC, DSPE-PEG2000, CHO, etc.; as well as protective agents and buffers salts used in vaccines, antibody proteins, antibody-conjugated drugs and other biological formulations, such as trehalose, sucrose, sucrose potassium octasulfate, etc.

Benzophenone-2, -6 and -8 protect cosmetics and personal care products from deterioration by absorbing, reflecting, or scattering UV rays. Benzophenone-8 when applied to the skin, absorbs UV rays. In addition to causing sunburn, UV radiation is a significant cause of premature aging of the skin and contributes to the development of melanoma and other forms of skin cancer. When used in OTC sunscreen drug humectant ingredients, Benzophenone-8 must be called Dioxybenzone.

E01A0015 Human Active Caspase 3 ELISA kit Human Active caspase 3 ELISA kit is suitable for the detection of samples from human species. Active caspase 3 can also be called CPP32, CPP32B, SCA1, Apoptain, Yama, Apoptosis-Related Cysteine Peptidase, Cysteinyl Aspartate Specific Proteinases 3, SREBP cleavage activity 1, Active casp3, casp3, casp-3, casp 3.

Most small molecule drugs are formulated as oral solid dosage (OSD) forms, such as tablets or capsules. OSD has been an important part of the global pharmaceutical market. The formulation team of Crystal Pharmatech is formed by technical experts with considerable experience in formulation development and dosage form optimization. We design and develop the solid dosage form and process tailor-made for your molecule based on a deep understanding of the material properties of API and to meet its intended clinical needs.

We will provide our valued customers with analytical chemistry testing research and quality control services for NCEs throughout their life cycle from the early clinical stage to commercial manufacturing. Analytical Method Development and Validation Guided by Quality by Design (QbD), we provide comprehensive analytical method development and validation in accordance with ICH Q2 based on Critical Quality Attributes (CQA) to support oral dosage form development. We also perform life cycle management to ensure quality research and control and provide accurate and reliable data at different drug development stages.

We will provide our valued customers with analytical chemistry testing services research and quality control services for NCEs throughout their life cycle from the early clinical stage to commercial manufacturing. Analytical Method Development and Validation Guided by Quality by Design (QbD), we provide comprehensive analytical method development and validation in accordance with ICH Q2 based on Critical Quality Attributes (CQA) to support oral dosage form development. We also perform life cycle management to ensure quality research and control and provide accurate and reliable data at different drug development stages.