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Casey Finnerty

CDC Features - Prevent the Spread of Norovirus - 0 views

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    "Norovirus Trends and Outbreaks"
Casey Finnerty

'One in five' struck by norovirus in Scotland say experts - Nottingham News - 0 views

  • the best way to protect yourself from the bug could be summed up in three words - "scrupulous personal hygiene".
Casey Finnerty

An influenza primer, updated for 2012/13 | Ars Technica - 0 views

Casey Finnerty

mBio - September/October 2012, 3 (5) - 0 views

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    This issue of mBio has several updates and opinion pieces on the H5N1 research moratorium.
Casey Finnerty

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission ... - 5 views

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    This paper by the Kawaoka group is the first report of an H5N1 virus that is transmissible by aerosol between mammals.
laceemarie

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets - 12 views

  • The MBCS in HA can be cleaved by ubiquitously expressed host proteases; this cleavage facilitates systemic virus replication and results in mortality of up to 100% in poultry (9, 10).
  • Although limited A/H5N1 virus transmission between persons in close contact has been reported, sustained human-to-human transmission of HPAI A/H5N1 virus has not been detected (13–15).
    • Casey Finnerty
       
      Could this not be happening?
  • The viruses that caused the major pandemics of the past century emerged upon reassortment (that is, genetic mixing) of animal and human influenza viruses (22).
    • Casey Finnerty
       
      How many pandemics are they talking about? Put another way, for how many pandemics in human history, do we have the virus on hand to analyze?
  • ...2 more annotations...
  • Influenza A viruses show pronounced genetic variation of the surface glycoproteins HA and NA
    • slgoogin8981
       
      Why is this an important site for variation?
    • laceemarie
       
      To be able to bind to a variety of different cells?
  • the factors that determine airborne transmission of influenza viruses among mammals, a trait necessary for a virus to become pandemic, have remained largely unknown (18–21)
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    This is the H5N1 mammal transmissibility paper from the Fouchier group.
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