Contents contributed and discussions participated by slgoogin8981 - WSU Virology

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation - 11 views

www.ncbi.nlm.nih.gov/...PMC3235490

shared by slgoogin8981 on 14 Nov 14 - No Cached

- slgoogin8981 on 24 Nov 14
  
  It is interesting to see that there are 3 allelic variants that correlate with disease prognosis, but how does this information benefit society? We can't change peoples genetic so to alter their prognosis. Is this just a benefit to know what medications would be most beneficial with the least amount of side effects?
  
  <div class="cArrow"> </div><div class="cContentInner">It is interesting to see that there are 3 allelic variants that correlate with disease prognosis, but how does this information benefit society? We can't change peoples genetic so to alter their prognosis. Is this just a benefit to know what medications would be most beneficial with the least amount of side effects?</div>
  
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Virus-Mediated Compartmentalization of the Host Translational Machinery - 22 views

mbio.asm.org/...e01463-14.full

shared by slgoogin8981 on 27 Oct 14 - No Cached

- slgoogin8981 on 19 Nov 14
  
  Does the viral factor protect the dsRNA from RIG-1? Earlier the paper spoke of energy balances, does the viral factor require a lot of energy to be created?
  
  <div class="cArrow"> </div><div class="cContentInner">Does the viral factor protect the dsRNA from RIG-1? Earlier the paper spoke of energy balances, does the viral factor require a lot of energy to be created?</div>
  
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HSV carrying WT REST establishes latency but reactivates only if the synthesis of REST ... - 7 views

www.pnas.org/...E498.long

shared by slgoogin8981 on 15 Oct 14 - No Cached

- slgoogin8981 on 19 Nov 14
  
  It would be interesting to know the amount that REST is seen in non-neural cells and nerve cells in the absents of HSV-1. I was state earlier that REST is not normally found in never cells.
  
  <div class="cArrow"> </div><div class="cContentInner">It would be interesting to know the amount that REST is seen in non-neural cells and nerve cells in the absents of HSV-1. I was state earlier that REST is not normally found in never cells. </div>
  
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Rabies Virus Hijacks and Accelerates the p75NTR Retrograde Axonal Transport Machinery - 14 views

www.ncbi.nlm.nih.gov/...PMC4148448

shared by slgoogin8981 on 03 Nov 14 - No Cached

slgoogin8981 on 03 Nov 14

Friday 11-7-14, paper

<div class="cArrow"> </div><div class="cContentInner">Friday 11-7-14, paper</div>

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BBC News - Brazil releases 'good' mosquitoes to fight dengue fever - 1 views

www.bbc.com/...world-latin-america-29356232

shared by slgoogin8981 on 26 Sep 14 - No Cached

Norovirus Translation Requires an Interaction between the C Terminus of the Genome-link... - 75 views

www.jbc.org/...21738.long

shared by slgoogin8981 on 12 Sep 14 - No Cached

inability to culture many members of the virus family in immortalized cells.
- slgoogin8981 on 17 Sep 14
  
  What are the other options to culture these viruses?
  
  <div class="cArrow"> </div><div class="cContentInner">What are the other options to culture these viruses?</div>
  
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we attempted
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to identify
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...3 more annotations...
components of the complex that interacted with VPg directly and contribute to viral translation
- slgoogin8981 on 18 Sep 14
  
  Is this the same as saying, they were looking for promoters?
  
  <div class="cArrow"> </div><div class="cContentInner">Is this the same as saying, they were looking for promoters?</div>
  
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recombinant MNV was performed by infecting baby hamster kidney cells with fowlpox virus expressing T7 RNA polymerase followed by transfection of MNV cDNA expression constructs as described previously
- slgoogin8981 on 19 Sep 14
  
  Was the fowlpox used just for the purpose of its polymerase? What is cDNA?
  
  <div class="cArrow"> </div><div class="cContentInner">Was the fowlpox used just for the purpose of its polymerase? What is cDNA?</div>
  
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- slgoogin8981 on 26 Sep 14
  
  Thank you for the link! I am very unskilled with the lab results and procedures done in lab. I appreciate the guidance and opportunity to learn. I have only had three biology labs: 241, 242 and Cell.
  
  <div class="cArrow"> </div><div class="cContentInner">Thank you for the link! I am very unskilled with the lab results and procedures done in lab. I appreciate the guidance and opportunity to learn. I have only had three biology labs: 241, 242 and Cell.</div>
  
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although these cells are not permissive to MNV infection due to the lack of a suitable receptor, robust MNV translation and replication occurs upon transfection of viral RNA into the cytoplasm (22).
- slgoogin8981 on 19 Sep 14
  
  It is very cool that this virus can still use human translation equipment even though it is a marine from of the virus. How did they enter the virus genome into the cytoplasm?
  
  <div class="cArrow"> </div><div class="cContentInner">It is very cool that this virus can still use human translation equipment even though it is a marine from of the virus. How did they enter the virus genome into the cytoplasm?</div>
  
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Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets - 12 views

www.sciencemag.org/...1534.full

shared by slgoogin8981 on 04 Dec 12 - No Cached

Influenza A viruses show pronounced genetic variation of the surface glycoproteins HA and NA
- slgoogin8981 on 05 Sep 14
  
  Why is this an important site for variation?
  
  <div class="cArrow"> </div><div class="cContentInner">Why is this an important site for variation?</div>
  
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