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Richard Herron

Escherichia coli O157:H7 - Wikipedia, the free encyclopedia - 1 views

  • Escherichia coli O157:H7 is an enterohemorrhagic strain of the bacterium Escherichia coli and a cause of illness through food.[1] Infection may lead to hemorrhagic diarrhea, and to kidney failure.
  • E. coli serotype O157:H7 is a Gram-negative, rod-shaped bacterium. The "O" in the name refers to the cell wall (somatic) antigen number, whereas the "H" refers to the flagella antigen.
Nellie Bogunovic

Drugs to Fight Deadly Superbugs in Short Supply - 0 views

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    With antibiotic resistance looming, the failure of drug companies to develop new drugs to fight gram-negative bacteria could potentially lead to millions of deaths just from a common cold or from the flu. Drug companies cannot turn out new antimicrobials fast enough, and the ones that they do get out to the public cost billions of dollars.
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    Scary to think that we're all at risk!
Casey Finnerty

Meningitis From Tainted Drugs Puts Patients, Doctors In Quandary : Shots - Health News ... - 0 views

  • 14,000 Americans
  • alert to illness among patients who have received injections of hundreds of other products
  • the number must run into the tens of thousands.
  • ...14 more annotations...
  • it was really a mini-pharmaceutical manufacturer, not the pharmacy it was licensed to be.
  • 1,200 different drugs
  • Apparently, all of this has been caused by contamination of drugs by a black mold called Exserohilum rostratum, which is common in the environment but almost unheard of as a cause of human disease.
  • For instance, on 13 occasions, they said, New England Compounding shipped out vials of drugs in three suspect lots before getting back results of their own tests confirming the drugs were sterile.
  • "indicated a failure ... to sterilize products for even the minimum amount of time necessary to ensure sterility,"
  • The firm's premises were not clean
  • medications were not labeled with individual patients' names
  • he may harbor a fungal infection that could kill him, there's no proof that he does — and there may never be.
  • many anxious patients are undergoing painful spinal taps and some are getting antifungal drugs that can damage the kidneys and liver.
  • The caution is warranted. This type of fungal infection can smolder for weeks and months before exploding into meningitis or causing massive strokes.
  • "It causes a quandary for the infectious disease doc to figure out, well, should this patient receive treatment at all?" O'Connell says. "Should they receive full-boat treatment, which would be an IV? Could they instead just be watched very closely with daily phone calls and visits to the office? We just don't know."
  • "Should we do lumbar punctures on those kinds of people so that we can anticipate those that are going to get symptomatic later and beat the fungus to it?" Schaffner wonders. "That is, initiate treatment much earlier, thus averting tissue damage, particularly those devastating strokes."
  • When to stop is also uncertain.
  • six months, maybe longer.
Casey Finnerty

Why Norovirus Crops Up on Cruises - NYTimes.com - 0 views

  • Over the past five years, an average of about 14 cruise ships a year have had outbreaks of diarrheal illness, and the culprit is almost always norovirus
  • The best way to avoid it is prevention, and the best prevention is hand washing.
  • The problem, he said, is passengers. “If Grandma is sick when she gets on, she’s going on the cruise anyway,” Dr. Vinjé said. “And that’s how the virus gets onboard. Then it lands on handrails and doorknobs, and the transmission continues.”
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  • regardless of the origin, once onboard, the illness spreads widely. He says the reason is failure to clean restrooms properly.
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