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Tyrell Varner

Surprising finding could alter the face of dengue vaccine development - 0 views

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    New leads reveal T-cell immunity may be an important key in the strong cross protection that occurs when dengue infected humans have two or more variations of the virus.
loryn_micro

Cairns suspected as source of dengue outbreak - ABC News (Australian Broadcasting Corpo... - 0 views

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    Posted April 29, 2013 10:33:53 The Townsville Public Health Unit says it suspects the outbreak of dengue fever in Townsville originated in Cairns. Eight cases of the virus has been confirmed in Townsville. Two more people are suspected of having the virus and test results are expected this afternoon.
Jenna Veldhuizen

Fighting disease from within the mosquito: New techniques to help halt the spread of di... - 0 views

  • When infected with the bacteria Wolbachia, mosquitoes are unable to spread viruses such as dengue
  • by introducing an insecticide resistance gene alongside the Wolbachia bacteria into the mosquito, that the insects pass on the disease-blocking bacteria to other mosquitoes faster
  • Our results show that Wolbachia-based strategies could hold the key to a cheap and sustainable approach to disease control
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    This in an interesting application in slowing the spread of diseases such as dengue and yellow fever, but one also has to wonder what this will do to the mosquito population as it reduces the mosquito's ability to lay viable eggs. How controlled will this application be and how often will it be utilized?
Tyrell Varner

How antibodies neutralize mosquito-borne virus - 1 views

  • The findings show the precise structure of the virus-like particle bound to a key part of the antibodies, called the antigen binding fragment, or Fab, which attaches to the heterodimers making up the virus's outer shell. The analyses showed that the antibodies stabilize the viral surface, hindering fusion to the host cell and likely neutralizing infection.
  • "This is the first time the structure of an alphavirus has been examined in this detail,"
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    This could help researchers find a vaccine for this disease, which has symptoms closely related to Dengue Fever.
Sean Hogan

Fighting disease from within the mosquito: New techniques to help halt the spread of di... - 1 views

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    Mosquitoes infected with the Wolbachia bacteria are unable to infect humans with diseases such as dengue, yellow fever, and possibly malaria. The bacteria the amount of productive eggs the mosquitoes can lay which makes passing along the bacteria difficult. To combat this the mosquitoes that are infected with the bacteria are also given a insecticide resistance gene. Because insecticide is a common preventative measure in parts of the world where the diseases are common, only those mosquitoes that are unable to spread disease would survive and pass along the bacteria.
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