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US Coronavirus: Daily deaths from Covid-19 just exceeded the deaths from 9/11 on this b... - 0 views

www.cnn.com/...index.html covid
shared by katherineharron on 10 Dec 20 - No Cached
  • The United States should be celebrating a day of great hope today, as a Covid-19 vaccine could get authorized for emergency use very soon.
  • Vaccine advisers for the US Food and Drug Administration are meeting Thursday to discuss the Pfizer/BioNTech vaccine.
  • That's more deaths than those suffered in the 9/11 attacks.
  • ...20 more annotations...
  • A new composite forecast from the US Centers for Disease Control and Prevention projects a total of 332,000 to 362,000 Covid-19 deaths by January 2.
  • Covid-19 hospitalizations also reached a new record high of 106,688 on Wednesday, according to the COVID Tracking Project.
  • more than 221,000 new infections were reported in just one da
  • "We are in a totally unprecedented health crisis in this country,"
  • Health care workers are exhausted. Hospitals are totally full."
  • "Unfortunately, with the volume of new cases that we are seeing and the implications it has on hospital utilization, during a period of widespread, community transmission, activities such as eating, drinking and smoking in close proximity to others, should not continue."
  • If the FDA grants emergency use authorization in the coming days, the first Americans outside of clinical trials could start getting inoculated this month.
  • in the coming months it's crucial that Americans stay vigilant and follow safety guidelines, like wearing face masks, social distancing and hunkering down in their social bubbles.
  • But the country will likely not see any meaningful impact until well into 2021 -- and that's if enough people get vaccinated, said Dr. Anthony Fauci, director of the National Institute for Allergy and Infectious Diseases.
  • "Let's say we get 75%, 80% of the population vaccinated. I believe if we do it efficiently enough over the second quarter of 2021, by the time we get to the end of the summer ... we may actually have enough herd immunity protecting our society that as we get to the end of 2021, we could approach very much, some degree of normality that is close to where we were before,"
  • "We want to make sure that the vaccines are actually administered, and we're afraid that won't happen," Paul Ostrowski, who is leading supply, production and distribution for Operation Warp Speed, told "Good Morning America" Wednesday.
  • "Baltimore City has not had to implement such severe restrictions since the very earliest days of the pandemic and the implementation of the stay-at-home order," the city's health department tweeted.
  • The daily death toll from Covid-19 reached a record high of 3,124 Wednesday, according to Johns Hopkins University.
  • Indiana's Republican Gov. Eric Holcomb ordered hospitals to postpone or reschedule non-emergency procedures done in an inpatient hospital setting from December 16 through January 3 to preserve hospital capacity.
  • In Alabama, Republican Gov. Kay Ivey announced Wednesday she's extending the state's Safer at Home order, which includes a statewide mask mandate for another six weeks.
  • About 53% of respondents said they would get the vaccine promptly -- up from 51% before Thanksgiving and 38% in early October.
  • The first emergency use authorization for a vaccine is expected soon, and about 20 million people could likely get vaccinated in the next few weeks, Secretary of Health and Human Services Alex Azar said Wednesday.
  • In the UK, "thousands" of people were already vaccinated Tuesday, the first day of the Pfizer/BioNTech vaccine rollout there, according to the National Health Service (NHS).
  • The FDA will not "cut any corners" when deciding whether to authorize the vaccine, Azar said, saying he was sure what happened in the UK would be "something the FDA looks at."
  • "For now, we need to double down on the steps that can keep us all safe."
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In a First, Man Receives a Heart From a Genetically Altered Pig - The New York Times - 0 views

www.nytimes.com/...rt-transplant-pig-bennett.html
shared by criscimagnael on 12 Jan 22 - No Cached
  • A 57-year-old man with life-threatening heart disease has received a heart from a genetically modified pig, a groundbreaking procedure that offers hope to hundreds of thousands of patients with failing organs.
  • “This is a watershed event,” said Dr. David Klassen, the chief medical officer of the United Network for Organ Sharing and a transplant physician. “Doors are starting to open that will lead, I believe, to major changes in how we treat organ failure.”
  • It creates the pulse, it creates the pressure, it is his heart,
  • ...24 more annotations...
  • It’s working and it looks normal. We are thrilled, but we don’t know what tomorrow will bring us. This has never been done before
  • Last year, some 41,354 Americans received a transplanted organ, more than half of them receiving kidneys,
  • But there is an acute shortage of organs, and about a dozen people on the lists die each day. Some 3,817 Americans received human donor hearts last year as replacements, more than ever before, but the potential demand is still higher.
  • Researchers hope procedures like this will usher in a new era in medicine in the future when replacement organs are no longer in short supply for the more than half a million Americans who are waiting for kidneys and other organs.
  • He is also being monitored for infections, including porcine retrovirus, a pig virus that may be transmitted to humans, although the risk is considered low.
  • But he added that there were many hurdles to overcome before such a procedure could be broadly applied, noting that rejection of organs occurs even when a well-matched human donor kidney is transplanted.
  • It takes a long time to mature a therapy like this.”
  • Mr. Bennett decided to gamble on the experimental treatment because he would have died without a new heart, had exhausted other treatments and was too sick to qualify for a human donor heart, family members and doctors said.
  • Mr. Bennett is still connected to a heart-lung bypass machine, which was keeping him alive before the operation, but that is not unusual for a new heart transplant recipient, experts said.
  • The new heart is functioning and already doing most of the work, and his doctors said he could be taken off the machine on Tuesday. Mr. Bennett is being closely monitored for signs that his body is rejecting the new organ, but the first 48 hours, which are critical, passed without incident.
  • It is the first successful transplant of a pig’s heart into a human being. The eight-hour operation took place in Baltimore on Friday, and the patient, David Bennett Sr. of Maryland, was doing well on Monday, according to surgeons at the University of Maryland Medical Center.
  • Xenotransplantation, the process of grafting or transplanting organs or tissues from animals to humans, has a long history. Efforts to use the blood and skin of animals go back hundreds of years.
  • In the 1960s, chimpanzee kidneys were transplanted into some human patients, but the longest a recipient lived was nine months.
  • In 1983, a baboon heart was transplanted into an infant known as Baby Fae, but she died 20 days later.
  • Two newer technologies — gene editing and cloning — have yielded genetically altered pig organs less likely to be rejected by humans.
  • the time to carry out better screening for infectious diseases, and the possibility of a new organ at the time that the patient needs it.
  • The heart transplanted into Mr. Bennett came from a genetically altered pig provided by Revivicor, a regenerative medicine company based in Blacksburg, Va.
  • The pig had 10 genetic modifications. Four genes were knocked out, or inactivated, including one that encodes a molecule that causes an aggressive human rejection response.
  • A growth gene was also inactivated to prevent the pig’s heart from continuing to grow after it was implanted,
  • In addition, six human genes were inserted into the genome of the donor pig — modifications designed to make the porcine organs more tolerable to the human immune system.
  • The team used a new experimental drug developed in part by Dr. Mohiuddin and made by Kiniksa Pharmaceuticals to suppress the immune system and prevent rejection.
  • “The anatomy was a little squirrelly, and we had a few moments of ‘uh-oh’ and had to do some clever plastic surgery to make everything fit,”
  • “the heart fired right up” and “the animal heart began to squeeze.”
  • He said his father had had a pig’s valve inserted about a decade ago, and he thought his father might be confused. But after a while, Mr. Bennett said, “I realized, ‘Man, he is telling the truth and not going crazy. And he could be the first ever.’”
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Opinion | It's 2086. This Is What American History Could Look Like. - The New York Times - 0 views

www.nytimes.com/...jan-6-shaman-past-future.html historiography revisionist condemnation US culture
shared by Javier E on 05 Jan 24 - No Cached
  • If it seems far-fetched that a notorious insurgent could be given such a place of honor, the past begs to differ. When the Confederate president, Jefferson Davis, was imprisoned after the Civil War (rumored to be dressed at the time of his arrest in his own outlandish costume), he was more reviled and mocked than any Capitol rioter, and his crimes far more serious. His statue joined George Washington’s in the Capitol 65 years later.
  • As curators at the Smithsonian’s National Museum of American History, we are regularly confronted by hard physical evidence of just how slippery the past can be.
  • It is chilling, but not impossible, to envision the signs screaming “Stop the steal!” picked up on the garbage-strewn National Mall on Jan. 7, 2021, treated one day as patriotic treasures, displayed alongside the writing desk Thomas Jefferson used to draft the Declaration of Independence or the inkwell Abraham Lincoln dipped into to compose the Emancipation Proclamation.
  • ...9 more annotations...
  • History, however, may have other plans. Contrary to the mantra, it has no right or wrong side.
  • Judging, it turns out, isn’t history’s strong suit. Notions of justice change radically over time, and they are not the reason we collect, preserve or display objects from the past
  • To curators and historians, the evolving meaning of our objects is far more fascinating than whom they label as unrighteous
  • The collections of the Smithsonian contain, for instance, pikes from John Brown’s failed slave rebellion in the South in 1859. At different moments since then, his pikes have symbolized a demented terrorist’s scheme for mass murder, a religious fanatic’s fiery crusade and a hero’s lonely struggle for justice.
  • Nothing in our past, no matter how blatant it may seem to us today, is guaranteed eternal condemnation
  • Our recent reckoning with American history has shown the indelible impact of staid forms of institutional power, like dedicating monuments, inscribing plaques and holding hearings. Enshrining rioters as heroes could be done fairly quietly.
  • There’s no controlling what the future will say about us. Generations just keep coming, re-evaluating old heroes and asking new questions.
  • We cannot know; we have no ownership over what is to come. The best we can do is map our moment scrupulously, to preserve the signposts that will lead to a place we’ll never see.
  • As curators, as historians, as citizens, we are frequently reminded that the past is a foreign country. But so is the future.
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