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Bishop Curry said that despite the “overwhelming” vote against his church, he saw signs of openness to change from the primates. “If this is of God, things will change in time,” he said. “And it may not be fast. I don’t know how long. But I know in my lifetime I’ve seen things change that I didn’t believe would ever change.”

But the presiding bishop of the Episcopal Church, Michael B. Curry, said in a telephone interview that he did not expect his church to reverse the decision it made last summer to permit same-sex marriages and to change the definition of marriage so that it was no longer defined by gender.

But Archbishop Welby said that the church’s provinces, while autonomous, were “interdependent” and obligated to one another not to deviate from doctrine. “And if you simply ignore that, there will be consequences,” he said.

The archbishop of Canterbury said there was no clarity about what would happen if the Americans did not reverse course and the Canadians moved to affirm gay marriage. “We’ll cross that bridge when we get to it,” he said at the news conference.

He also announced that he intended to hold the next international assembly of Anglican bishops, known as a Lambeth Conference, in 2020. With schism averted at least temporarily, Archbishop Welby said that Friday, the primates agreed to join discussions with the Coptic Church leader, Pope Tawadros II, and Pope Francis, leader of the Roman Catholic Church, to set a common date for Easter.

Wrangham’s 2009 book, Catching Fire: How Cooking Made Us Human, pursued a very different hypothesis. Based on archaeological evidence, he made the case that our ancestors mastered fire much earlier than most of us had believed—perhaps closer to 2 million rather than 800,000 years ago—which changed everything for them

In his 1996 book, Demonic Males, co-authored with Dale Peterson, Wrangham recapped this and other evidence to draw a dire portrait of humanity (the male version) as inherently violent by evolutionary legacy. Here was vivid support for a Hobbesian view of human nature, rooted in genetics.

his two previous books, which explore the opposing poles of behavior. Renowned for his meticulous fieldwork, especially with chimps in Uganda’s Kibale National Park, Wrangham showed just how common chimp brutality is.

He also applies his evolutionary logic to studies of a wider array of animals. He dwells in particular on some marvelous experiments that explore the taming of wild foxes, minks, and other species by human-directed artificial selection over many generations.

fire extended the day into the night. Given how important we know conversations and stories told around the fire are to human hunter-gatherers, it’s easy to see how this process could have accelerated the evolution of language—an essential ingredient for less physically aggressive interactions

evidence has steadily accumulated that humans, from early on in their development, are the most cooperative species in the primate world

classic work on chimps has been complemented by new studies of bonobos, our other close relative. No more removed from us genetically than chimps are, they are a radical contrast to them, often called the “make love, not war” species. Some of our nonhuman kin, such fieldwork has revealed, can live and evolve almost without violence.

he pursues yet another ambitious hypothesis: “Reduced reactive aggression must feature alongside intelligence, cooperation, and social learning as a key contributor to the emergence and success of our species.”

“I walked around Auschwitz. I could feel the chimera at its best and worst.” Violence and virtue, he recognizes, are not opposites but powerful, not always reliable allies. “So much cooperation,” he notes of the smoothly operating human machinery of mass murder—“it can be for good or bad.”

cooking made possible a much more diverse diet

Enter the bonobos, to whom Wrangham turns as he considers how diminished aggression may have been selected for in the evolution of humans

they separated from chimps 1 to 2 million years ago, and were isolated south of a bend in the Congo River. Female bonobos form strong coalitions—partly based on sex with each other—that keep a lid on male violence. The “trust hormone” oxytocin is released during female sex: You could say that the partners are high, in both senses of the word, on trust. Because females run things, males don’t attack them, and even male-on-male violence is extremely limited. Bonobos also display the other traits common to the domestication syndrome, which suggests—as in the case of the foxes—a broad genetic dynamic at work.

He has learned that over many generations, ecological realities create species-specific behavior. In the case of bonobos, he suggests, a lush habitat in which they were protected from competition with either chimps or gorillas gave them the luxury of decreasing their own reactive aggression

Central to his argument is the idea that cooperative killing of incurably violent individuals played a central role in our self-domestication

our ancestors killed men who were guilty of repeated acts of violence. Certainly all-male raiding parties have operated in some groups of humans, seeking out and killing victims in neighboring villages

They serve as a form of capital punishment. Wrangham cites a number of examples of anthropologists witnessing a group of men collaborating to kill a violent man in their midst.

My own two years with the !Kung point to a more robust possible selection process for winnowing out aggression: female choice. Women in most hunter-gatherer groups, as I learned in the course of my experience in the field, are closer to equality with men than are women in many other societies. Evolutionary logic suggests that young women and their parents, in choosing less violent mates through the generations, could provide steady selection pressure toward lower reactive aggression—steadier pressure than infrequent dramas of capital punishment could. (

Wrangham has nonetheless highlighted a puzzle at the core of human evolution, and delivered a reminder of the double-edged nature of our virtues and vices.

Such breeding efforts, Wrangham notes, have produced “the domestication syndrome”: a change in a suite of traits, not just the low reactive aggression that breeders have deliberately singled out

Half a century and thousands of fossil finds later, we have a far more complete—and also more puzzling—view of the human past

As data pile up, so do surprises

In 1965 a remarkable book—Irven DeVore’s collection Primate Behavior (which led me to study with DeVore)—made what then seemed a radical claim: We will never understand our origins without intensive study of the wild world of our nonhuman relatives. A handful of scientists, including Jane Goodall, set up tents in distant jungles and savannas. Following monkeys, apes, and other creatures in their habitats, these scientists turned their notes and observations into voluminous, quantitative data.

It also created a new and more complex social structure. The bands who exchanged women with each other learned to cooperate, forming a group or tribe that would protect its territory from other tribes. Though cooperation became the norm within a tribe, tribes would wage warfare just as relentlessly as chimpanzee bands.

A system of cooperative bands “provides the kind of social infrastructure that can really get things going,” he said. In a series of experiments comparing human and chimpanzee infants, Dr. Tomasello has shown that very young children have an urge to help others. One of these skills is what he calls shared intentionality, the ability to form a plan with others for accomplishing a joint endeavor. Children, but not chimps, will point at things to convey information, they will intuit others’ intentions from the direction of their gaze, and they will help others achieve a goal.

Cooperation may have been forced on them as a condition of existence. “Humans were put under some kind of collective pressure to collaborate in their gathering of food — they became obligate collaborators — in a way that their closest primate relatives were not,”

Humans wear the mark of their shared intentionality, he notes, in a small but significant feature — the whites of their eyes, which are three times larger than those of any other primate, presumably to help others follow the direction of gaze.

The primary resource for detailing the path of human evolution will always be fossil specimens.

In devising such scenarios and filling in the human family bush, researchers must consult a large and diverse array of fossils, and they must also employ refined excavation methods and records, geochemical dating techniques, and data from other specialized fields such as genetics, ecology and paleoecology, and ethology (animal behaviour)—in short, all the tools of the multidisciplinary science of paleoanthropology.

It is generally agreed that the taproot of the human family shrub is to be found among apelike species of the Middle Miocene Epoch (roughly 16–11.6 mya) or Late Miocene Epoch (11.6–5.3 mya). Genetic data based on molecular clock estimates support a Late Miocene ancestry. Various Eurasian and African Miocene primates have been advocated as possible ancestors to the early hominins, which came on the scene during the Pliocene Epoch (5.3–2.6 mya)

There are three hundred and twenty-one testing locations in the city, and the system is so extensive that in June, when Beijing suffered an outbreak, Wuhan hospitals sent seventy-two staffers to the capital to help with tests.

When Wuhan was sealed, the strategy of isolation was replicated throughout the city. Housing compounds were closed and monitored by neighborhood committees, with residents going out only for necessities.

Toward the end of the first month, the guidelines were tightened further, until virtually all goods were delivered. On February 17th, Fang Fang wrote, “Everyone is now required to remain inside their homes at all times.”

Meanwhile, approximately ten thousand contact tracers were working in the city, in order to cut off chains of infection, and hospitals were developing large-scale testing systems. But isolation remained crucial: patients were isolated; suspected exposures were isolated; medical workers were isolated.

Zhang said the experience of working through the pandemic had left him calmer and more patient. He drove more carefully now; he wasn’t in such a rush.

I often asked Wuhan residents how they had been personally changed by the spring, and there was no standard response. Some expressed less trust in government information; others said they had increased faith in the national leadership.

Wuhan had most recently reported a locally transmitted symptomatic case on May 18th. It’s the most thoroughly tested city in China: at the end of May, in part to boost confidence, the government tried to test every resident, a total of eleven million.

I never met a cabdriver who had been swab-tested less than twice, and a couple had been tested five times. Most of the cabbies had no relatives or friends who had been infected; swabbing was simply required by the city and by their cab companies.

“I tend to take a charitable view of countries that are at the beginning stage of epidemics,” Jennifer Nuzzo, an epidemiologist at the Johns Hopkins Center for Health Security, told me, in a phone conversation. According to her, it’s unrealistic to expect that any country could have stopped this particular virus at its source. “I’ve always believed that this thing was going to spread,” she said

The physician who handled testing told me that, on average, his hospital still recorded one positive for every forty thousand exams. Most of these positives were repeat patients: after having been infected during the initial run of the virus, they recovered fully, and then for some reason, months later, showed evidence of the virus again. So far, most of the positives had been asymptomatic, and the physician saw no indication that the virus was spreading in the city.

In town, there were few propaganda signs about the epidemic, and Wuhan newspapers ran upbeat headlines every morning (Yangtze Daily, August 29th, front page: “STUDENTS DO NOT HAVE TO WEAR MASKS IN SCHOOLS”). Movie theatres were open; restaurants and bars had no seating restrictions. At the Hanyang Renxinghui Mall, I saw barefaced kids playing in what may have been one of the last fully functioning ball pits on earth, a sight that seemed worthy of other headlines (“CHILDREN DO NOT HAVE TO WEAR MASKS IN WUHAN BALL PITS”).

Across town, colleges and universities were in the process of bringing back more than a million students. Wuhan has the second-highest number of students of any city in China, after Guangzhou.

Wuhan memories remained fresh, and the materials of documentation were also close at hand. People sometimes handed over manuscripts, and they took out their phones and pulled up photographs and messages from January and February. But I wondered how much of this material would dissipate over time.

In town, I met two Chinese journalists in their twenties who were visiting from out of town. They had been posted during the period of the sealed city: back then, anybody sent to cover events in Wuhan had to stay for the long haul.

One was a director of streaming media whom I’ll call Han, and he had found that government-run outlets generally wanted footage that emphasized the victory over the disease, not the suffering of Wuhan residents. Han hoped that eventually he’d find other ways to use the material. “It will be in the hard drive,” he said, tapping his camera.

After that, Yin reported on a number of issues that couldn’t be published or completed, and she often talked with scientists and officials who didn’t want to say too much. “One person said, ‘Ten years later, if the climate has changed, I’ll tell you my story,’ ” Yin told me. “He knew that he would be judged by history.” She continued, “These people are inside the system, but they also know that they are inside history.”

Such fare is much more popular in Guangdong, in the far south. It’s possible that the disease arrived from somewhere else and then spread in the wet, cool conditions of the fish stalls. A few Wuhan residents told me that a considerable amount of their seafood comes from Guangdong, and they suggested that perhaps a southerner had unwittingly imported the disease,

When I spoke with scientists outside China, they weren’t focussed on the government’s early missteps

In time, we will learn more, but the delay is important to the Communist Party. It handles history the same way that it handles the pandemic—a period of isolation is crucial. Throughout the Communist era, there have been many moments of quarantined history: the Great Leap Forward, the Cultural Revolution, the massacre around Tiananmen Square. In every case, an initial silencing has been followed by sporadic outbreaks of leaked information. Wuhan will eventually follow the same pattern, but for the time being many memories will remain in the sealed city.

Wafaa El-Sadr, the director of ICAP, a global-health center at Columbia University, pointed out that Chinese scientists had quickly sequenced the virus’s genome, which was made available to researchers worldwide on January 11th. “I honestly think that they had a horrific situation in Wuhan and they were able to contain it,” she said. “There were mistakes early on, but they did act, and they shared fast.”

For much of El-Sadr’s career, she has worked on issues related to AIDS in the United States, Africa, and elsewhere. After years of research, scientists eventually came to the consensus that H.I.V. most likely started through the bushmeat trade—the first human was probably infected after coming into contact with a primate or primate meat.

El-Sadr views the coronavirus as another inevitable outcome of people’s encroachment on the natural world. “We are now living through two concomitant massive pandemics that are the result of spillover from animal to human hosts, the H.I.V. and the COVID pandemics,” she wrote to me, in an e-mail. “Never in history has humanity experienced something along this scale and scope.”

There’s a tendency to believe that we would know the source of the coronavirus if the Chinese had been more forthcoming, or if they hadn’t cleaned out the Huanan market before stalls and animals could be studied properly.

Yiwu He, the chief innovation officer at the University of Hong Kong, told me that the C.N.B.G. vaccine has already been given to a number of Chinese government officials, under an emergency-use approval granted by the authorities. “I know a few government officials personally, and they told me that they took the vaccine,” he said, in a phone conversation. He thought that the total number was probably around a hundred. “It’s middle-level officials,” he said. “Vice-ministers, mayors, vice-mayors.”

Daszak believes the virus probably circulated for weeks before the Wuhan outbreak, and he doubts that the city was the source. “There are bats in Wuhan, but it was the wrong time of year,” he told me. “It was winter, and bats are not out as much.”

His research has indicated that, across Southeast Asia, more than a million people each year are infected by bat coronaviruses. Some individuals trap, deal, or raise animals that might serve as intermediary hosts. “But generally it’s people who live near bat caves,”

Daszak said that he had always thought that such an outbreak was most likely to occur in Kunming or Guangzhou, southern cities that are close to many bat caves and that also have an intensive wildlife trade.

He thinks that Chinese scientists are probably now searching hospital freezers for lab samples of people who died of pneumonia shortly before the outbreak. “You would take those samples and look for the virus,” he said. “They’ll find something eventually. These things just don’t happen overnight; it requires a lot of work. We’ve seen this repeatedly with every disease. It turns out that it was already trickling through the population.”

Daszak is the president of EcoHealth Alliance, a nonprofit research organization based in New York. EcoHealth has become the target of conspiracy theorists, including some who claim that the virus was man-made. Daszak and many prominent virologists say that anything created in a lab would show clear signs of manipulation.

There’s also speculation that the outbreak started when researchers accidentally released a coronavirus they were studying at the Wuhan Institute of Virology. But there’s no evidence of a leak, or even that the institute has ever studied a virus that could cause a COVID-19 outbreak.

“Scientists in China are under incredible pressure to publish,” Daszak said. “It really drives openness and transparency.”

He has spent a good deal of time in Wuhan, and co-authored more than a dozen papers with Chinese colleagues. “If we had found a virus that infected human cells and spread within a cell culture, we would have put the information out there,” he said. “In sixteen years, I’ve never come across the slightest hint of subterfuge. They’ve never hidden data. I’ve never had a situation where one lab person tells me one thing and the other says something else. If you were doing things that you didn’t want people to know about, why would you invite foreigners into the lab?”

In April, President Trump told reporters that the U.S. should stop funding research connected to the Wuhan Institute of Virology. Shortly after Trump’s comments, the National Institutes of Health cancelled a $3.7-million grant to EcoHealth, which had been studying how bat coronaviruses are transmitted to people.

I asked Daszak why, if he has such faith in the openness of his Wuhan colleagues, the Chinese government has been so closed about other aspects of the outbreak. He said that science is one thing, and politics something else; he thinks that officials were embarrassed about the early mistakes, and in response they simply shut down all information.

At the beginning of July, China National Biotec Group, a subsidiary of a state-owned pharmaceutical company called Sinopharm, completed construction of a vaccine-manufacturing plant in Wuhan. The project began while the city was still sealed. “That’s the politically correct thing to do,” a Shanghai-based biotech entrepreneur told me. “To show the world that the heroic people of Wuhan have come back.”

But Peter Daszak, a British disease ecologist who has collaborated with the Wuhan Institute of Virology for sixteen years on research on bat coronaviruses, told me that it’s typical to fail to gather good data from the site of an initial outbreak. Once people get sick, local authorities inevitably focus on the public-health emergency. “You send in the human doctors, not the veterinarians,” he said, in a phone conversation. “And the doctors’ response is to clean out the market. They want to stop the infections.”

Pharmaceutical executives have also been expected to lead the way, like the construction manager who donned P.P.E. in order to escort his workers into the patient ward. “Every senior executive at Sinopharm and C.N.B.G. has been vaccinated,” He said. “Including the C.E.O. of Sinopharm, the chairman of the board, every vice-president—everyone.” The Chinese press has reported that vaccinations have also been administered to hundreds of thousands of citizens in high-risk areas around the world.

In the West, China’s image has been badly damaged by the pandemic and by other recent events. The country has tightened political crackdowns in Hong Kong and Xinjiang, and, in May, after Australia called for an investigation into the origins of the virus, China responded furiously, placing new tariffs and restrictions on Australian goods ranging from barley to beef.

But He believes that the situation is fluid. “All of these feelings can turn around quickly,” he told me. “I think that once China has a vaccine, and if they can help other countries, it can make a huge difference.”

There’s also a competitive element. “China wants to beat America,” He said. He believes that the C.N.B.G. vaccine will receive some level of approval for public use by the end of October. “Chinese officials are thinking that Donald Trump might approve a U.S. vaccine before the election,” he said. “So their goal is to have a vaccine approved before that.”

No matter how quickly the Chinese develop a vaccine, or how effectively they have handled the pandemic since January, it’s unlikely to make Westerners forget the mistakes and misinformation during the pandemic’s earliest phase.

Some of this is due to a cultural difference—the Chinese response to errors is often to look forward, not back. On January 31st, Fang Fang commented in her diary, “The Chinese people have never been fond of admitting their own mistakes, nor do they have a very strong sense of repentance.” It’s often hard for them to understand why this quality is so frustrating for Westerners. In this regard, the pandemic is truly a mirror—it doesn’t allow the Chinese to look out and see themselves through the eyes of others.

The pandemic illuminates both the weaknesses and the strengths of the Chinese system, as well as the relationship between the government and the people. They know each other well: officials never felt the need to tell citizens exactly what happened in Wuhan, but they understood that American-level casualties would have been shocking—given China’s population, the tally would have been more than a million and counting.

In order to avoid death on that scale, the government also knew that people would be willing to accept strict lockdowns and contribute their own efforts toward fighting the virus.

In turn, citizens were skilled at reading their government. People often held two apparently contradictory ideas: that the Party lied about some things but gave good guidance about others. More often than not, citizens could discern the difference. During the pandemic, it was striking that, when the Chinese indulged in conspiracy theories, these ideas rarely resulted in personally risky behavior, as they often did in the U.S.

Perhaps the Chinese have been inoculated by decades of censorship and misinformation: in such an environment, people develop strong instincts for self-preservation, and they don’t seem as disoriented by social media as many Americans are.

Early in the year, I corresponded by WeChat with a Wuhan pharmacist who worked in a hospital where many were infected. On February 26th, he expressed anger about the early coverup. “My personal opinion is that the government has always been careless and suppressed dissent,” he wrote. “Because of this, they lost a golden opportunity to control the virus.”

In Wuhan, we met a few times, and during one of our conversations I showed him what he had written in February. I asked what he would do now if he found himself in Li Wenliang’s position, aware of an outbreak of some unknown disease. Would he post a warning online? Contact a health official? Alert a journalist?The pharmacist thought for a moment. “I would tell my close friends in person,” he said. “But I wouldn’t put anything online. Nothing in writing.”

I asked if such an event would turn out differently now.“It would be the same,” he said. “It’s a problem with the system.”

He explained that, with an authoritarian government, local officials are afraid of alarming superiors, which makes them inclined to cover things up. But, once higher-level leaders finally grasp the truth, they can act quickly and effectively.

Conservative leaders are indeed ideologically extreme, but they’re also deeply incompetent. So much so, in fact, that the Dunning-Kruger effect — the truly incompetent can’t even recognize their own incompetence — reigns supreme.

Even more remarkable, in its way, was the response of House Republican leaders, who didn’t tell the activists they were being foolish. All they did was urge that the extortion attempt be made over the debt ceiling rather than a government shutdown.

It has been obvious for years that the modern Republican Party is no longer capable of thinking seriously about policy. Whether the issue is climate change or inflation, party members believe what they want to believe, and any contrary evidence is dismissed as a hoax, the product of vast liberal conspiracies.

Sooner or later, the party’s attitude toward policy — we listen only to people who tell us what we want to hear, and attack the bearers of uncomfortable news — was bound to infect political strategy, too.

Everybody not inside the bubble realizes that Mr. Obama can’t and won’t negotiate under the threat that the House will blow up the economy if he doesn’t — any concession at all would legitimize extortion as a routine part of politics. Yet Republican leaders are just beginning to get a clue, and so far clearly have no idea how to back down. Meanwhile, the government is shut, and a debt crisis looms. Incompetence can be a terrible thing.

To be soaked in materialism, to directly and indirectly champion it, has also brought guilt. I don’t know if I have a right to the vast quantities of materials and energy I consume in my daily life. Even if I thought I did, I know the planet cannot bear my lifestyle multiplied by 7 billion individuals. I believe this understanding is shared, if only subconsciously, by almost everyone in the Western world.

Every last trifle we touch and consume, right down to the paper on which this magazine is printed or the screen on which it’s displayed, is not only ephemeral but in a real sense irreplaceable. Every consumer good has a cost not borne out by its price but instead falsely bolstered by a vanishing resource economy. We squander millions of years’ worth of stored energy, stored life, from our planet to make not only things that are critical to our survival and comfort but also things that simply satisfy our innate primate desire to possess. It’s this guilt that we attempt to assuage with the hope that our consumerist culture is making life better—for ourselves, of course, but also in some lesser way for those who cannot afford to buy everything we purchase, consume, or own. When that small appeasement is challenged even slightly, when that thin, taut cord that connects our consumption to the nameless millions who make our lifestyle possible snaps even for a moment, the gulf we find ourselves peering into—a yawning, endless future of emptiness on a squandered planet—becomes too much to bear.

The most anxiety-producing jobs are the ones in which the employee has very little control over what he or she does during the workday.

One thing that "Outliers" fails to point out is that practice alone is not enough. Anders Erickson, a psychologist at Florida State University who studies peak human performance, argues that practicing the same thing over and over again does not ensure that you will respond well in a stressful situation. The trick is to challenge yourself so you're constantly improving your skills.

The most frustrating thing about a traffic jam is not that we're stuck sitting there. For the most part, we're perfectly comfortable in our cars. The problem is that we have no control over what's going on -- we have no idea as to when the traffic will eventually let up. Those are the exact ingredients that make people anxious. Anger and fear are very similar physiologically, so that's why some people get stressed and some people get pissed. It's all part of the same fight-or-flight reaction cycle.

The notion of executive stress syndrome -- the idea that bosses and corporate executives experience much higher levels of anxiety than their underlings -- has proven to be total bullshit. Executives tend to have more control over what they're doing, and they often displace their anxieties on the people that work beneath them.

certain phobias can be made extinct by repeated exposure to what scares us.

only way to beat these feelings -- and by beat I do not mean extinguish so much as get in a more comfortable relationship with -- is to put yourself in the very situations that make you so uncomfortable.

“I remember the chain of thought,” he said. “I had to do prehistory, so I have to do some archaeology. But to do it seriously, I’m going to talk about how humans evolved, so, yikes, I’m in biology now. I thought: To do it seriously, I have to talk about how mammals evolved, how primates evolved. I have to go back to multicelled organisms, I have to go back to primeval slime. And then I thought: I have to talk about how life was created, how life appeared on earth! I have to talk geology, the history of the planet. And so you can see, this is pushing me back and back and back, until I realized there’s a stopping point — which is the Big Bang.” He paused. “I thought, Boy, would that be exciting to teach a course like this!”

In the wake of McNeill’s rebuke, Western Civ was slowly replaced by World History, a more comparative class that stressed broad themes across cultures and disciplines. Over the past 30 years, World History has produced its own formidable academic institutions and journals; these days, three-quarters of all American students take World History

by the early ‘70s, as the Vietnam War heightened interest in nations outside Europe, Western Civ was on the decline. In pedagogical circles, a book called “The Rise of the West: A History of the Human Community,” by William Hardy McNeill, a historian at the University of Chicago, persuasively argued that Western Civ was not merely biased against other cultures but also failed to account for the enormous influence that cultures had on one another over the millenniums.

Christian, who is 67, now travels the world as something of an evangelist for the spread of the Big History Project. (His TED Talk, “The History of Our World in 18 Minutes,” has been viewed more than four million times online.)

They have monitored teacher feedback closely and decreased the course in size, from 20 units to 10. True to Christian’s original style, however, the high-school course links insights across subjects into wildly ambitious narratives. The units begin with the Big Bang and shift to lesson plans on the solar system, trade and communications, globalization and, finally, the future. A class on the emergence of life might start with photosynthesis before moving on to eukaryotes and multicellular organisms and the genius of Charles Darwin and James Watson. A lecture on the slave trade might include the history of coffee beans in Ethiopia.

“Most kids experience school as one damn course after another; there’s nothing to build connections between the courses that they take,” says Bob Bain, a professor of history and education at the University of Michigan and an adviser to the Big History Project, who has helped devise much of the curriculum. “The average kid has no way to make sense between what happens with their first-period World History class and their second-period algebra class, third-period gym class, fourth-period literature — it’s all disconnected. It’s like if I were to give you a jigsaw puzzle and throw 500 pieces on the table and say, ‘Oh, by the way, I’m not going to show you the box top as to how they fit together.’ ”

Gates has insisted on tracking this venture as he would any Microsoft product or foundation project. The Big History Project produces reams of data — students and teachers are regularly surveyed, and teachers submit the results from classes, all of which allows his team to track what’s working and what isn’t as the course grows. “Our priority,” he told me from across the table, “was to get it into a form where ambitious teachers could latch onto it.”

Few schools had teachers who were willing or able to instruct a hybrid course; some schools wound up requiring that two teachers lead the class together. Gates, who had hoped to avoid bureaucracy, found himself mired in it. “You’ve got to get a teacher in the history department and the science department — they have to be very serious about it, and they have to get their administrative staff to agree. And then you have to get it on the course schedule so kids can sign up,” he said. “So they have to decide, kind of in the spring or earlier, and those teachers have to spend a lot of that summer getting themselves ready for the thing.”

Perhaps the largest challenge facing the Big History Project, however, is Gates himself, or at least the specter of him. To his bafflement and frustration, he has become a remarkably polarizing figure in the education world. This owes largely to the fact that Gates, through his foundation, has spent more than $200 million to advocate for the Common Core, something of a third rail in education circles

Diane Ravitch, an education historian at New York University who has been a vocal critic of Gates, put even it more starkly: “When I think about history, I think about different perspectives, clashing points of view. I wonder how Bill Gates would treat the robber barons. I wonder how Bill Gates would deal with issues of extremes of wealth and poverty.”

“It begins to be a question of: Is this Bill Gates’s history? And should it be labeled ‘Bill Gates’s History’? Because Bill Gates’s history would be very different from somebody else’s who wasn’t worth $50-60 billion.”

perhaps, Big History might even become a successor to Western Civ and World History.

he also noted that Big History — which is already being offered in South Korea, the Netherlands and, of course, Australia — had significant global potential.

Sam Wineburg, a professor of education and history at Stanford, told me that although he sees Big History as “an important intellectual movement,” he did not consider the class to be a suitable replacement for an actual history course. “At certain points, it becomes less history and more of a kind of evolutionary biology or quantum physics. It loses the compelling aspect that is at the heart of the word ‘history.’ ”

Wineburg’s deepest concern about the approach was its failure to impart a methodology to students. “What is most pressing for American high-school students right now, in the history-social-studies curriculum, is: How do we read a text? How do we connect our ability to sharpen our intellectual capabilities when we’re evaluating sources and trying to understand human motivation?” he asked. “When we think about history, what are the primary sources of Big History? The original scientific reports of the Big Bang?”

Barr, the principal in Brooklyn, however, came to feel that Gates’s course was better than the existing alternative. “If you were to interview many, many progressive social-studies teachers, they would tell you that World History is a completely flawed course. It’s spotty. It’s like fact soup. Kids don’t come out of it really having a sense of global history,”

Ever since the liberal Episcopal Church in America consecrated Canon Gene Robinson - a divorced man in a gay relationship - as bishop of New Hampshire in November 2003, sniping within the Communion has intensified.

"It would not be good if the Church is unable to set an example to the world of showing how we can love one another and disagree profoundly, because we are brought together by Jesus Christ, not by our own choice."

A split in the Anglican Church over the issue of homosexuality "would not be a disaster, but it would be a failure", the Archbishop of Canterbury has said.

Given the fractious Primates' meetings of the past, the Archbishop of Canterbury has done well simply in persuading all 38 to meet around one table, using much of the personal capital he built up during his visits to every single Anglican province around the globe.

The more liberal provinces that are open to changing Church doctrine on marriage in order to allow for same-sex unions include Brazil, Canada, New Zealand, Scotland, South India, South Africa, the US and Wales.

A spokesman for the archbishop added the meeting would be an opportunity for national churches to decide their approach to the next Lambeth Conference - the once-in-a-decade gathering of the worldwide Anglican bishops.

A letter sent recently by more than 100 senior Anglicans to the Archbishops of Canterbury and York urging them to ensure the Church repents for "discriminating" against lesbian and gay Christians will be discussed too. It called for the Church to acknowledge members around the world have been treated as "second-class citizens".

They were able to reverse engineer the ancient climate by analyzing temperature-sensitive structures of lipids produced by fossil bacteria and archaea living in these bygone wetlands, and preserved for all time in the coal. The team found that, under this past regime of high CO2, in the ancient U.K., Germany, and New Zealand, life endured mean annual temperatures of 23–29 degrees Celsius (73–84 degrees Fahrenheit) or 10–15 degrees Celsius (18–27 degrees Fahrenheit) warmer than modern times.

“These wetlands looked exactly how only tropical wetlands look at present, like the Everglades or the Amazon,” Naafs says. “So Europe would look like the Everglades and a heat wave like we’re currently experiencing in Europe would be completely normal. That is, it would be the everyday climate.”

But over 50 million years ago this would have been the baseline from about 45 to 60 degrees latitude. Under this broiling regime, with unprecedented heat as the norm, actual heat waves might have begun to take on an unearthly quality.

closer to the equator in this global sweat lodge, the heat might have been even more outrageous, shattering the limits of complex life. To see exactly how hot, Naafs’ team also analyzed ancient lignite samples from India, which would have been in the tropics at the time—that subcontinent still drifting across the Indian Ocean toward its eventual mountain-raising rendezvous with Asia. But unfortunately, the temperatures from these samples were maxed out. That is, they were too hot for his team to measure by the new methods they had developed.

“Some climate models suggest that the tropics just became a dead zone with temperatures over 50 degrees Celsius (122 degrees Fahrenheit) like in Africa and South America,” says Naafs. “But we have no data so we don’t know.”

“Basically every type of paleoclimate research that’s being done shows that high CO2 means that it’s very warm. And when it gets very warm, it can be really, really, really warm.

“You start really looking into them and you go, ‘Wow. We are dealing with a rainforest.’”

“You’ve got alligators, giant tortoises, primates, things like that. We have these big hippo-like animals called Coryphodon. You have tapirs—so you’ve got tapirs living pretty close to the North Pole in the early Eocene, which today—clearly tapirs are not at the North Pole,” she says, laughing.

One obvious way to reconcile this disparity is by noticing that the changes to the ancient earth took place over hundreds-of-thousands to millions of years and (IPCC graphs notwithstanding) that time won’t stop at the end of the 21st century. The changes that we’ve already set in motion, unless we act rapidly to countervail them, will similarly take millennia to fully unfold

we’re clearly not content to stop at just 400 ppm. If we do, in fact, push CO2 up to around 1,000 ppm by the end of the century, the warming will persist and the earth will continue to change for what, to humans, is a practical eternity

Most worryingly, the climate models that we depend on as a species to predict our future have largely failed to predict our sultry ancient past.

we know methane can actually amplify high-latitude warming, so maybe that’s some of the missing feedback.

Though there are no trees here at the top of the world, there are tree stumps. And they are around 50 million years old.

Clearly we are missing something, and Naafs thinks that one of the missing ingredients in the models is methane, a powerful greenhouse gas which might help close the divide between model worlds and fossil worlds.

We know tropical wetlands pump much more methane into the atmosphere compared to [cooler] wetlands.

The last time CO2 was at 400 ppm (as it is today) was 3 million years ago during the Pliocene epoch, when sea levels were perhaps 80 feet higher than today.

Naafs thinks that many of the wildest features of the early age of mammals could be recreated.

Parents, heeding the advice of physicians and even the U.S. government, adopted a style of care that was chilly and aloof.

With the development of compound microscopes in the 1600s, scientists got their first glimpse of microorganisms. In the mid-19th century, Louis Pasteur and Robert Koch demonstrated that bacteria were the agents of some diseases. By the close of the century, scientists identified viruses.

All that would shift again by the middle of the 20th century, when psychologists such as John Bowlby and Harry Harlow exposed the potentially traumatic side effects of remote parenting on child development.

In ancient times, disease was thought to be the result of an imbalance of body fluids or an affliction from the gods. Later, scientists suspected that illnesses might be transmitted through the air or water, but weren’t clear how.

In 1870, 175 of every 1,000 infants died in their first year of life; by 1930, the number decreased to 75. Yet the hands-off approach that kept children safe from germs also ran counter to the instinctual need for physical affection that all primates, including humans, have.

Refrigerators and vacuum cleaners were marketed not only as labor savers but as necessities for good hygiene. When the DuPont Cellophane Co. brought out plastic wrap in the 1920s, the product was hailed as a sanitary innovation for keeping food and other personal items.

In 1888, the “Wife’s Handbook” warned mothers that a single touch was teeming with deadly germs that might harm her infant, and public campaigns urged caution when preparing family meals.

Harlow’s and Bowlby’s insights set the stage for a shift toward child-centered and emotionally connected parenting that remains in fashion today. But it came too late for generations whose upbringings were marked by an excessive fear of germs

Growing evidence points to a connection between destructive environmental practices and emerging diseases.

Of more than 330 diseases which emerged between 1940 and 2004, nearly two-thirds were zoonotic, meaning they were transmitted from animals to humans, as with, for example, HIV/AIDS and probably covid-19.

over 70% originated in wildlife,

Replacing old-growth forests with a single crop, such as oil palm, can also lead to the transmission of disease. If predators’ habitats are destroyed and their populations dwindle, other creatures such as rodents, mosquitoes, bats and some primates can proliferate.

scientists are increasingly turning their attention to how altering land interferes with a pathogen’s journey from animals to humans

felling trees increases contact between humans and disease-carrying animals

correlation between the loss of forests in west and central Africa and outbreaks of Ebola between 2004 and 2014

Cutting down trees may also increase the threat to humans posed by viral infections transmitted through mosquito bites, such as Zika, dengue and chikungunya.

link between changes in global forest cover between 1990 and 2016 and an increase in reported epidemics, even accounting for the fact that deforestation usually means more humans living nearby

Wildlife may also move towards human settlements in search of food. Mango trees planted on pig farms in Malaysia probably attracted fruit bats carrying nipah, a virus that infected local pig farmers in 1999 and still breaks out yearly in Bangladesh.

The decision has to come this month “because of the time required for manufacturing the necessary doses,” three of FDA’s top officials – FDA Commissioner Robert Califf, vaccine expert Peter Marks and principal deputy commissioner Janet Woodcock – wrote in a paper published by the journal JAMA in May.Both Pfizer and Moderna are studying vaccines designed to combat omicron and other strains. However, data on the shots remains scarce.

Despite mounting anticipation for the decision, the percentage of parents who will get their young children vaccinated is likely to be low compared to other age groups. A survey from February found that 31% of parents of children in the age range will get their kid vaccinated right away if a vaccine is authorized.

Clinical data from Moderna’s shot is expected this month, according to the company. Moderna in April released findings to support its booster shot development strategy, but the data comes after research in animals suggested the omicron-specific shot might not provide additional protection. A study from scientists at the National Institutes of Allergy and Infectious Diseases’s Vaccine Research Center found that primates boosted with the original vaccine had similar levels of protection as monkeys who got an omicro

The Biden administration has warned of potential fall and winter surges infecting up to 100 million Americans as it gears up for a fall booster shot campaign, whether that is with an omicron-specific shot or not. The FDA authorized a fourth vaccine dose for people ages 50 and older in March, and expanding the shot to more age groups is under consideration.“Administering additional COVID-19 vaccine doses to appropriate individuals this fall around the time of the usual influenza vaccine campaign has the potential to protect susceptible individuals against hospitalization and death, and therefore will be a topic for FDA consideration,” the officials wrote.In fact, the officials said that coronavirus booster shots could be on their way to becoming a yearly occurrence.

It is time to “accept that the presence of SARS-CoV-2, the virus that causes COVID-19, is the new normal,” according to the officials.“It will likely circulate globally for the foreseeable future, taking its place alongside other common respiratory viruses such as influenza,” they wrote.But paying for the shots remains an issue for the Biden administration as Congress shows little appetite for approving more COVID-19 funding.

Bonobos became famous for showing that nature didn’t always have to be red in tooth and claw. “Bonobos are an icon for peace and love, the world’s ‘hippie chimps,’” Sally Coxe, a conservationist, said in 2006.

Because bonobos live in remote, swampy rainforests, it has been much more difficult to observe them in the wild than chimpanzees. More recent research has shown that bonobos live a more aggressive life than their reputation would suggest.

In a study based on thousands of hours of observations in the wild published on Friday, for example, researchers found that male bonobos commit acts of aggression nearly three times as often as male chimpanzees do.

“There is no ‘hippie ape,’”

As our closest living relatives, bonobos and chimpanzees can offer us clues about the roots of human behavior. We and the two species share a common ancestor that lived about 7 million years ago. About 5 million years later, bonobos split off from chimpanzees.

In 2012, a trio of Harvard researchers proposed that bonobos evolved much like dogs did. Less aggressive wolves were not as likely to be killed by humans, which over time led to the emergence of dogs. In a similar fashion, the researchers argued, female bonobos preferred to mate with less aggressive males, giving birth to less aggressive offspring.

The researchers called their idea the self-domestication hypothesis. In later years, they speculated that humans may have undergone a self-domestication of their own.

Dr. Mouginot soon became perplexed, as she saw that male bonobos acted aggressively on a regular basis. Unlike male chimpanzees, who started their days in a mellow mood, the male bonobos seemed to wake up ready for a fight.

She and her colleagues trained field assistants, who made more observations throughout the pandemic. The new analysis, based on 9,300 hours of observations on 12 male bonobos and 14 male chimpanzees, found that bonobos committed aggressive acts 2.8 times as frequently as than the chimpanzees did.

Dr. Mouginot found that the frequent bonobo aggressions almost always involved a single male attacking another male. Chimpanzees, in contrast, often ganged up to attack a victim.

the study set a new standard for comparing aggression in bonobos and chimpanzees.

Dr. Mouginot speculated that male chimpanzees engage in one-on-one aggression less often because it poses bigger dangers: A victim of aggression may not want to go on a border patrol with the perpetrator, for example. Or he may bring back some of his own allies to wreak vengeance.

It may be easier for male bonobos to get away with aggression, Dr. Mouginot said, because in their female-dominated society they don’t face the risks that come with male alliances. “I think that’s why we see more aggression in bonobos — because it’s less risky to act aggressively against other males,”

the apes that carried out the most aggressive acts were also the ones who mated most often.

parts of the self-domestication hypothesis “clearly need refinement.” It may be important to consider the effect that different kinds of aggression have on a species, rather than lumping them altogether, he said.

Still, he argued that the differences between the two species remained significant. “Chimpanzees murder, and bonobos don’t,

Dr. Shi’s group was fascinated by how coronaviruses jump from species to species. To find viruses, they took samples from bats and other animals, as well as from sick people living near animals carrying these viruses or associated with the wildlife trade. Much of this work was conducted in partnership with the EcoHealth Alliance, a U.S.-based scientific organization that, since 2002, has been awarded over $80 million in federal funding to research the risks of emerging infectious diseases.

Their research showed that the viruses most similar to SARS‑CoV‑2, the virus that caused the pandemic, circulate in bats that live roughly 1,000 miles away from Wuhan. Scientists from Dr. Shi’s team traveled repeatedly to Yunnan province to collect these viruses and had expanded their search to Southeast Asia. Bats in other parts of China have not been found to carry viruses that are as closely related to SARS-CoV-2.

When the Covid-19 outbreak was detected, Dr. Shi initially wondered if the novel coronavirus had come from her laboratory, saying she had never expected such an outbreak to occur in Wuhan.

The SARS‑CoV‑2 virus is exceptionally contagious and can jump from species to species like wildfire. Yet it left no known trace of infection at its source or anywhere along what would have been a thousand-mile journey before emerging in Wuhan.

The year before the outbreak, the Wuhan institute, working with U.S. partners, had proposed creating viruses with SARS‑CoV‑2’s defining feature

The laboratory pursued risky research that resulted in viruses becoming more infectious: Coronaviruses were grown from samples from infected animals and genetically reconstructed and recombined to create new viruses unknown in nature. These new viruses were passed through cells from bats, pigs, primates and humans and were used to infect civets and humanized mice (mice modified with human genes). In essence, this process forced these viruses to adapt to new host species, and the viruses with mutations that allowed them to thrive emerged as victors.

Worse still, as the pandemic raged, their American collaborators failed to publicly reveal the existence of the Defuse proposal. The president of EcoHealth, Peter Daszak, recently admitted to Congress that he doesn’t know about virus samples collected by the Wuhan institute after 2015 and never asked the lab’s scientists if they had started the work described in Defuse.

By 2019, Dr. Shi’s group had published a database describing more than 22,000 collected wildlife samples. But external access was shut off in the fall of 2019, and the database was not shared with American collaborators even after the pandemic started, when such a rich virus collection would have been most useful in tracking the origin of SARS‑CoV‑2. It remains unclear whether the Wuhan institute possessed a precursor of the pandemic virus.

In 2021, The Intercept published a leaked 2018 grant proposal for a research project named Defuse, which had been written as a collaboration between EcoHealth, the Wuhan institute and Ralph Baric at the University of North Carolina, who had been on the cutting edge of coronavirus research for years. The proposal described plans to create viruses strikingly similar to SARS‑CoV‑2.

Coronaviruses bear their name because their surface is studded with protein spikes, like a spiky crown, which they use to enter animal cells. The Defuse project proposed to search for and create SARS-like viruses carrying spikes with a unique feature: a furin cleavage site — the same feature that enhances SARS‑CoV‑2’s infectiousness in humans, making it capable of causing a pandemic. Defuse was never funded by the United States.

owever, in his testimony on Monday, Dr. Fauci explained that the Wuhan institute would not need to rely on U.S. funding to pursue research independently.

While it’s possible that the furin cleavage site could have evolved naturally (as seen in some distantly related coronaviruses), out of the hundreds of SARS-like viruses cataloged by scientists, SARS‑CoV‑2 is the only one known to possess a furin cleavage site in its spike. And the genetic data suggest that the virus had only recently gained the furin cleavage site before it started the pandemic.

Ultimately, a never-before-seen SARS-like virus with a newly introduced furin cleavage site, matching the description in the Wuhan institute’s Defuse proposal, caused an outbreak in Wuhan less than two years after the proposal was drafted.

When the Wuhan scientists published their seminal paper about Covid-19 as the pandemic roared to life in 2020, they did not mention the virus’s furin cleavage site — a feature they should have been on the lookout for, according to their own grant proposal, and a feature quickly recognized by other scientists.

At the Wuhan Institute of Virology, a team of scientists had been hunting for SARS-like viruses for over a decade, led by Shi Zhengl

In May, citing failures in EcoHealth’s monitoring of risky experiments conducted at the Wuhan lab, the Biden administration suspended all federal funding for the organization and Dr. Daszak, and initiated proceedings to bar them from receiving future grants. In his testimony on Monday, Dr. Fauci said that he supported the decision to suspend and bar EcoHealth.

Separately, Dr. Baric described the competitive dynamic between his research group and the institute when he told Congress that the Wuhan scientists would probably not have shared their most interesting newly discovered viruses with him. Documents and email correspondence between the institute and Dr. Baric are still being withheld from the public while their release is fiercely contested in litigation.

In the end, American partners very likely knew of only a fraction of the research done in Wuhan. According to U.S. intelligence sources, some of the institute’s virus research was classified or conducted with or on behalf of the Chinese military.

In the congressional hearing on Monday, Dr. Fauci repeatedly acknowledged the lack of visibility into experiments conducted at the Wuhan institute, saying, “None of us can know everything that’s going on in China, or in Wuhan, or what have you. And that’s the reason why — I say today, and I’ve said at the T.I.,” referring to his transcribed interview with the subcommittee, “I keep an open mind as to what the origin is.”

The Wuhan lab pursued this type of work under low biosafety conditions that could not have contained an airborne virus as infectious as SARS‑CoV‑2.

Labs working with live viruses generally operate at one of four biosafety levels (known in ascending order of stringency as BSL-1, 2, 3 and 4) that describe the work practices that are considered sufficiently safe depending on the characteristics of each pathogen. The Wuhan institute’s scientists worked with SARS-like viruses under inappropriately low biosafety conditions.

​​Biosafety levels are not internationally standardized, and some countries use more permissive protocols than others.

In one experiment, Dr. Shi’s group genetically engineered an unexpectedly deadly SARS-like virus (not closely related to SARS‑CoV‑2) that exhibited a 10,000-fold increase in the quantity of virus in the lungs and brains of humanized mice. Wuhan institute scientists handled these live viruses at low biosafety levels, including BSL-2.

Even the much more stringent containment at BSL-3 cannot fully prevent SARS‑CoV‑2 from escaping. Two years into the pandemic, the virus infected a scientist in a BSL-3 laboratory in Taiwan, which was, at the time, a zero-Covid country. The scientist had been vaccinated and was tested only after losing the sense of smell. By then, more than 100 close contacts had been exposed. Human error is a source of exposure even at the highest biosafety levels, and the risks are much greater for scientists working with infectious pathogens at low biosafety.

An early draft of the Defuse proposal stated that the Wuhan lab would do their virus work at BSL-2 to make it “highly cost-effective.” Dr. Baric added a note to the draft highlighting the importance of using BSL-3 to contain SARS-like viruses that could infect human cells, writing that “U.S. researchers will likely freak out.”

Years later, after SARS‑CoV‑2 had killed millions, Dr. Baric wrote to Dr. Daszak: “I have no doubt that they followed state determined rules and did the work under BSL-2. Yes China has the right to set their own policy. You believe this was appropriate containment if you want but don’t expect me to believe it. Moreover, don’t insult my intelligence by trying to feed me this load of BS.”

SARS‑CoV‑2 is a stealthy virus that transmits effectively through the air, causes a range of symptoms similar to those of other common respiratory diseases and can be spread by infected people before symptoms even appear. If the virus had escaped from a BSL-2 laboratory in 2019, the leak most likely would have gone undetected until too late.

One alarming detail — leaked to The Wall Street Journal and confirmed by current and former U.S. government officials — is that scientists on Dr. Shi’s team fell ill with Covid-like symptoms in the fall of 2019. One of the scientists had been named in the Defuse proposal as the person in charge of virus discovery work. The scientists denied having been sick.

The hypothesis that Covid-19 came from an animal at the Huanan Seafood Market in Wuhan is not supported by strong evidence.

In December 2019, Chinese investigators assumed the outbreak had started at a centrally located market frequented by thousands of visitors daily. This bias in their search for early cases meant that cases unlinked to or located far away from the market would very likely have been missed

To make things worse, the Chinese authorities blocked the reporting of early cases not linked to the market and, claiming biosafety precautions, ordered the destruction of patient samples on January 3, 2020, making it nearly impossible to see the complete picture of the earliest Covid-19 cases. Information about dozens of early cases from November and December 2019 remains inaccessible.

A pair of papers published in Science in 2022 made the best case for SARS‑CoV‑2 having emerged naturally from human-animal contact at the Wuhan market by focusing on a map of the early cases and asserting that the virus had jumped from animals into humans twice at the market in 2019

More recently, the two papers have been countered by other virologists and scientists who convincingly demonstrate that the available market evidence does not distinguish between a human superspreader event and a natural spillover at the market.

Furthermore, the existing genetic and early case data show that all known Covid-19 cases probably stem from a single introduction of SARS‑CoV‑2 into people, and the outbreak at the Wuhan market probably happened after the virus had already been circulating in humans.

Not a single infected animal has ever been confirmed at the market or in its supply chain. Without good evidence that the pandemic started at the Huanan Seafood Market, the fact that the virus emerged in Wuhan points squarely at its unique SARS-like virus laboratory.

With today’s technology, scientists can detect how respiratory viruses — including SARS, MERS and the flu — circulate in animals while making repeated attempts to jump across species. Thankfully, these variants usually fail to transmit well after crossing over to a new species and tend to die off after a small number of infections

investigators have not reported finding any animals infected with SARS‑CoV‑2 that had not been infected by humans. Yet, infected animal sources and other connective pieces of evidence were found for the earlier SARS and MERS outbreaks as quickly as within a few days, despite the less advanced viral forensic technologies of two decades ago.

Even though Wuhan is the home base of virus hunters with world-leading expertise in tracking novel SARS-like viruses, investigators have either failed to collect or report key evidence that would be expected if Covid-19 emerged from the wildlife trade. For example, investigators have not determined that the earliest known cases had exposure to intermediate host animals before falling ill.

No antibody evidence shows that animal traders in Wuhan are regularly exposed to SARS-like viruses, as would be expected in such situations.

In previous outbreaks of coronaviruses, scientists were able to demonstrate natural origin by collecting multiple pieces of evidence linking infected humans to infected animals

In contrast, virologists and other scientists agree that SARS‑CoV‑2 required little to no adaptation to spread rapidly in humans and other animals. The virus appears to have succeeded in causing a pandemic upon its only detected jump into humans.

it was a SARS-like coronavirus with a unique furin cleavage site that emerged in Wuhan, less than two years after scientists, sometimes working under inadequate biosafety conditions, proposed collecting and creating viruses of that same design.

a laboratory accident is the most parsimonious explanation of how the pandemic began.

Given what we now know, investigators should follow their strongest leads and subpoena all exchanges between the Wuhan scientists and their international partners, including unpublished research proposals, manuscripts, data and commercial orders. In particular, exchanges from 2018 and 2019 — the critical two years before the emergence of Covid-19 — are very likely to be illuminating (and require no cooperation from the Chinese government to acquire), yet they remain beyond the public’s view more than four years after the pandemic began.

it is undeniable that U.S. federal funding helped to build an unprecedented collection of SARS-like viruses at the Wuhan institute, as well as contributing to research that enhanced them.

Advocates and funders of the institute’s research, including Dr. Fauci, should cooperate with the investigation to help identify and close the loopholes that allowed such dangerous work to occur. The world must not continue to bear the intolerable risks of research with the potential to cause pandemics.

A successful investigation of the pandemic’s root cause would have the power to break a decades-long scientific impasse on pathogen research safety, determining how governments will spend billions of dollars to prevent future pandemics. A credible investigation would also deter future acts of negligence and deceit by demonstrating that it is indeed possible to be held accountable for causing a viral pandemic

Last but not least, people of all nations need to see their leaders — and especially, their scientists — heading the charge to find out what caused this world-shaking event. Restoring public trust in science and government leadership requires it.