An international comparison of serum 25-hydroxyvitamin D measurements.
Lips P, Chapuy MC, Dawson-Hughes B, Pols HA, Holick MF.
Osteoporos Int. 1999;9(5):394-7.
PMID: 10550457
DOI: 10.1007/s001980050162
The results show that 25(OH)D values from different laboratories can not be assumed to be comparable unless a careful cross-calibration has been performed.
Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality.
Dobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz W.
Arch Intern Med. 2008 Jun 23;168(12):1340-9.
PMID: 18574092
Conclusions Low 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D levels are independently associated with all-cause and cardiovascular mortality. A causal relationship has yet to be proved by intervention trials using vitamin D.
25-hydroxyvitamin D and risk of myocardial infarction in men: a prospective study.
Giovannucci E, Liu Y, Hollis BW, Rimm EB.
Arch Intern Med. 2008 Jun 9;168(11):1174-80.
PMID: 18541825
Conclusion Low levels of 25(OH)D are associated with higher risk of myocardial infarction in a graded manner, even after controlling for factors known to be associated with coronary artery disease.
The Standing Committee of European Doctors (CPME) is preparing a vitamin D policy paper it hopes can influence European national associations considering vitamin D medical recommendations.
PA International Foundation is hosting an event on the topic in Bruges, Belgium, on October 6, its 14th workshop to be held on the matter. The CPME draft paper will be presented at the convention attended by doctors, scientists, patient groups, media representatives and politicians.
Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the Third National Health and Nutrition Examination Survey.
Ginde AA, Mansbach JM, Camargo CA Jr.
Arch Intern Med. 2009 Feb 23;169(4):384-90.
PMID: 19237723
Conclusions Serum 25(OH)D levels are inversely associated with recent URTI. This association may be stronger in those with respiratory tract diseases. Randomized controlled trials are warranted to explore the effects of vitamin D supplementation on RTI.
Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004.
Ginde AA, Liu MC, Camargo CA Jr.
Arch Intern Med. 2009 Mar 23;169(6):626-32.
PMID: 19307527
Conclusions National data demonstrate a marked decrease in serum 25(OH)D levels from the 1988-1994 to the 2001-2004 NHANES data collections. Racial/ethnic differences have persisted and may have important implications for known health disparities. Current recommendations for vitamin D supplementation are inadequate to address the growing epidemic of vitamin D insufficiency.
The review, published in Osteoporosis International, provides a global perspective of vitamin D status across different regions of the world and identifies common and significant determinants of hypovitaminosis D. Six regions of the world were reviewed-Asia, Europe, Middle East and Africa, Latin America, North America, and Oceania-through a survey of published literature.
A high prevalence of hypovitaminosis D in Finnish medical in- and outpatients.
Kauppinen-Mäkelin R, Tähtelä R, Löyttyniemi E, Kärkkäinen J, Välimäki MJ.
J Intern Med. 2001 Jun;249(6):559-63.
PMID: 11422663
DOI: 10.1046/j.1365-2796.2001.00847.x
CONCLUSION: Hypovitaminosis D is very common amongst Finnish in- and outpatients in both sexes, causing secondary hyperparathyroidism in females. More extensive studies are warranted to elucidate the vitamin D status of the Finnish population.
Serum levels of free 1,25-dihydroxyvitamin D in vitamin D toxicity.
Pettifor JM, Bikle DD, Cavaleros M, Zachen D, Kamdar MC, Ross FP.
Ann Intern Med. 1995 Apr 1;122(7):511-3.
PMID: 7872586
CONCLUSIONS: Although the patients had normal or near-normal total 1,25-(OH)2D values, most patients had elevated free 1,25-(OH)2D levels. These findings suggest that elevated free 1,25-(OH)2D levels might play a role in the pathogenesis of hypercalcemia in vitamin D toxicity.
Association Between Serum 25-Hydroxyvitamin D Level and Upper Respiratory Tract Infection. \nAdit A. Ginde, MD, MPH; Jonathan M. Mansbach, MD; Carlos A. Camargo Jr, MD, DrPH . \nArch Intern Med. 2009;169(4):384-390\n
Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials.
Autier P, Gandini S.
Arch Intern Med. 2007 Sep 10;167(16):1730-7. Review.
PMID: 17846391
Conclusions Intake of ordinary doses of vitamin D supplements seems to be associated with decreases in total mortality rates. The relationship between baseline vitamin D status, dose of vitamin D supplements, and total mortality rates remains to be investigated. Population-based, placebo-controlled randomized trials with total mortality as the main end point should be organized for confirming these findings.
Demographic differences and trends of vitamin D insufficiency in the US population, 1988-2004.
Ginde AA, Liu MC, Camargo CA Jr.
Arch Intern Med. 2009 Mar 23;169(6):626-32.
PMID: 19307527
Conclusions National data demonstrate a marked decrease in serum 25(OH)D levels from the 1988-1994 to the 2001-2004 NHANES data collections. Racial/ethnic differences have persisted and may have important implications for known health disparities. Current recommendations for vitamin D supplementation are inadequate to address the growing epidemic of vitamin D insufficiency.
Prevention of nonvertebral fractures with oral vitamin D and dose dependency: a meta-analysis of randomized controlled trials.
Bischoff-Ferrari HA, Willett WC, Wong JB, Stuck AE, Staehelin HB, Orav EJ, Thoma A, Kiel DP, Henschkowski J.
Arch Intern Med. 2009 Mar 23;169(6):551-61.
PMID: 19307517
Conclusion Nonvertebral fracture prevention with vitamin D is dose dependent, and a higher dose should reduce fractures by at least 20% for individuals aged 65 years or older.
Glerup H, Mikkelsen K, Poulsen L, Hass E, Overbeck S, Thomsen J, Charles P, Eriksen EF. Commonly recommended daily intake of vitamin D is not sufficient if sunlight exposure is limited.J Intern Med. 2000 Feb;247(2):260-8.PMID: 10692090 [PubMed - indexed f
Hypocalcemia as a Cause of Reversible Cardiomyopathy with Ventricular Tachycardia
Chandrakant B. Chavan, MD, DNB; Kalavakolanu Sharada, MD, DM; Hygriv B. Rao, MD, DM; and Calambur Narsimhan, MD, DM, AB
Annals of Internal Medicine, 3 April 2007, Volume
Chatfield SM, Brand C, Ebeling PR, Russell DM. Vitamin D deficiency in general medical inpatients in summer and winter. Intern Med J. 2007 Jun;37(6):377-82. PMID: 17535381 [PubMed - in process]
Independent association of low serum 25-hydroxyvitamin d and 1,25-dihydroxyvitamin d levels with all-cause and cardiovascular mortality.\nDobnig H, Pilz S, Scharnagl H, Renner W, Seelhorst U, Wellnitz B, Kinkeldei J, Boehm BO, Weihrauch G, Maerz W.\nArch Intern Med. 2008 Jun 23;168(12):1340-9.\nPMID: 18574092
25-hydroxyvitamin D levels and the risk of mortality in the general population.
Melamed ML, Michos ED, Post W, Astor B.
Arch Intern Med. 2008 Aug 11;168(15):1629-37.
PMID: 18695076
Effects of vitamin D supplementation on symptoms of depression in overweight and obese subjects: randomized double blind trial.
Jorde R, Sneve M, Figenschau Y, Svartberg J, Waterloo K.
J Intern Med. 2008 Dec;264(6):599-609. Epub 2008 Sep 10.
PMID: 18793245
Conclusions. It appears to be a relation between serum levels of 25(OH)D and symptoms of depression. Supplementation with high doses of vitamin D seems to ameliorate these symptoms indicating a possible causal relationship.
Vitamin D as an analgesic for patients with type 2 diabetes and neuropathic pain.
Lee P, Chen R.
Arch Intern Med. 2008 Apr 14;168(7):771-2.
PMID: 18413561