The Twitalyzer is a unique tool to evaluate the activity of any Twitter user and report on relative influence, signal-to-noise ratio, generosity, velocity, clout, and other useful measures of success in social media.
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His UK generated list of most influential non celebrity tweeters includes NPR's Andy Carvin. It is interesting how many personalities cross time zones and national lines to influence us all. Andy is a great tweeter. Sadly, this list doesn't seem to link. Kind of misses the point but worth a read anyway.