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In short, a complex and evolving system — whether that’s a flock of gold finches or a nebula or the English language — will produce ever more diverse and intricately detailed states and configurations of itself.

Some of these more diverse and intricate configurations, the scientists write, are shed and forgotten over time. The configurations that persist are ones that find some utility or novel function in a process akin to natural selection, but a selection process driven by the passing-on of information rather than just the sowing of biological genes

Have they finally glimpsed, I wonder, the connectedness and symbiotic co-evolution of their own scientific ideas with those of the world’s writers

Have they learned to describe in their own quantifying language that cradle from which both our disciplines have emerged and the firmament on which they both stand — the hearing and telling of stories in order to exist?

Have they quantified the quality of all existent matter, living and not: that all things inherit a story in data to tell, and that our stories are told by the very forms we take to tell them? 

“Is there a universal basis for selection? Is there a more quantitative formalism underlying this conjectured conceptual equivalence—a formalism rooted in the transfer of information?,” they ask of the world’s disparate phenomena. “The answer to both questions is yes.”

Yes. They’ve glimpsed it, whether they know it or not. Sing to me, O Muse, of functional information and its complex diversity.

The principle of complexity evolving at its own pace when left to its own devices, independent of time but certainly in a dance with it, is nothing new. Not in science, nor in its closest humanities kin, science and nature writing. Give things time and nourishing environs, protect them from your own intrusions and — living organisms or not — they will produce abundant enlacement of forms.

This is how poetry was born from the same larynxes and phalanges that tendered nuclear equations: We featherless bipeds gave language our time and delighted attendance until its forms were so multivariate that they overflowed with inevitable utility.

In her Pulitzer-winning “Pilgrim at Tinker Creek,” nature writer Annie Dillard explains plainly that evolution is the vehicle of such intricacy in the natural world, as much as it is in our own thoughts and actions. 

“The stability of simple forms is the sturdy base from which more complex, stable forms might arise, forming in turn more complex forms,” she explains, drawing on the undercap frills of mushrooms and filament-fine filtering tubes inside human kidneys to illustrate her point. 

“Utility to the creature is evolution’s only aesthetic consideration. Form follows function in the created world, so far as I know, and the creature that functions, however bizarre, survives to perpetuate its form,” writes Dillard.

“Of the multiplicity of forms, I know nothing. Except that, apparently, anything goes. This holds for forms of behavior as well as design — the mantis munching her mate, the frog wintering in mud.” 

She notes that, of all forms of life we’ve ever known to exist, only about 10% are still alive. What extravagant multiplicity. 

“Intricacy is that which is given from the beginning, the birthright, and in the intricacy is the hardiness of complexity that ensures against the failures of all life,” Dillard writes. “The wonder is — given the errant nature of freedom and the burgeoning texture of time — the wonder is that all the forms are not monsters, that there is beauty at all, grace gratuitous.”

“This paper, and the reason why I'm so proud of it, is because it really represents a connection between science and the philosophy of science that perhaps offers a new lens into why we see everything that we see in the universe,” lead scientist Michael Wong told Motherboard in a recent interview. 

Wong is an astrobiologist and planetary scientist at the Carnegie Institute for Science. In his team’s paper, that bridge toward scientific philosophy is not only preceded by a long history of literary creativity but directly theorizes about the creative act itself.  

“The creation of art and music may seem to have very little to do with the maintenance of society, but their origins may stem from the need to transmit information and create bonds among communities, and to this day, they enrich life in innumerable ways,” Wong’s team writes.  

“Perhaps, like eddies swirling off of a primary flow field, selection pressures for ancillary functions can become so distant from the core functions of their host systems that they can effectively be treated as independently evolving systems,” the authors add, pointing toward the elaborate mating dance culture observed in birds of paradise.

“Perhaps it will be humanity’s ability to learn, invent, and adopt new collective modes of being that will lead to its long-term persistence as a planetary phenomenon. In light of these considerations, we suspect that the general principles of selection and function discussed here may also apply to the evolution of symbolic and social systems.”

The Mekhilta teaches that all Ten Commandments were pronounced in a single utterance. Similarly, the Maharsha says the Torah’s 613 mitzvoth are only perceived as a plurality because we’re time-bound humans, even though they together form a singular truth which is indivisible from He who expressed it. 

Or, as the Mishna would have it, “the creations were all made in generic form, and they gradually expanded.” 

Like swirling eddies off of a primary flow field.

“O Lord, how manifold are thy works!,” cried out David in his psalm. “In wisdom hast thou made them all: the earth is full of thy riches. So is this great and wide sea, wherein are things creeping innumerable, both small and great beasts.” 

In all things, then — from poetic inventions, to rare biodiverse ecosystems, to the charted history of our interstellar equations — it is best if we conserve our world’s intellectual and physical diversity, for both the study and testimony of its immeasurable multiplicity.

Because, whether wittingly or not, science is singing the tune of the humanities. And whether expressed in algebraic logic or ancient Greek hymn, its chorus is the same throughout the universe: Be fruitful and multiply. 

Both intricate configurations of art and matter arise and fade according to their shared characteristic, long-known by students of the humanities: each have been graced with enough time to attend to the necessary affairs of their most enduring pleasures. 

For the well-being of its users, Bejar argued, Meta needed to change course, focusing less on a flawed system of rules-based policing and more on addressing such bad experiences

The company would need to collect data on what upset users and then work to combat the source of it, nudging those who made others uncomfortable to improve their behavior and isolating communities of users who deliberately sought to harm others.

“I am appealing to you because I believe that working this way will require a culture shift,” Bejar wrote to Zuckerberg—the company would have to acknowledge that its existing approach to governing Facebook and Instagram wasn’t working.

During and after Bejar’s time as a consultant, Meta spokesman Andy Stone said, the company has rolled out several product features meant to address some of the Well-Being Team’s findings. Those features include warnings to users before they post comments that Meta’s automated systems flag as potentially offensive, and reminders to be kind when sending direct messages to users like content creators who receive a large volume of messages. 

Meta’s classifiers were reliable enough to remove only a low single-digit percentage of hate speech with any degree of precision.

Bejar was floored—all the more so when he learned that virtually all of his daughter’s friends had been subjected to similar harassment. “DTF?” a user they’d never met would ask, using shorthand for a vulgar proposition. Instagram acted so rarely on reports of such behavior that the girls no longer bothered reporting them. 

Meta’s own statistics suggested that big problems didn’t exist. 

Meta had come to approach governing user behavior as an overwhelmingly automated process. Engineers would compile data sets of unacceptable content—things like terrorism, pornography, bullying or “excessive gore”—and then train machine-learning models to screen future content for similar material.

While users could still flag things that upset them, Meta shifted resources away from reviewing them. To discourage users from filing reports, internal documents from 2019 show, Meta added steps to the reporting process. Meta said the changes were meant to discourage frivolous reports and educate users about platform rules. 

The outperformance of Meta’s automated enforcement relied on what Bejar considered two sleights of hand. The systems didn’t catch anywhere near the majority of banned content—only the majority of what the company ultimately removed

“Please don’t talk about my underage tits,” Bejar’s daughter shot back before reporting his comment to Instagram. A few days later, the platform got back to her: The insult didn’t violate its community guidelines.

Also buttressing Meta’s statistics were rules written narrowly enough to ban only unambiguously vile material. Meta’s rules didn’t clearly prohibit adults from flooding the comments section on a teenager’s posts with kiss emojis or posting pictures of kids in their underwear, inviting their followers to “see more” in a private Facebook Messenger group. 

“Mark personally values freedom of expression first and foremost and would say this is a feature and not a bug,” Rosen responded

Narrow rules and unreliable automated enforcement systems left a lot of room for bad behavior—but they made the company’s child-safety statistics look pretty good according to Meta’s metric of choice: prevalence.

Defined as the percentage of content viewed worldwide that explicitly violates a Meta rule, prevalence was the company’s preferred measuring stick for the problems users experienced.

According to prevalence, child exploitation was so rare on the platform that it couldn’t be reliably estimated, less than 0.05%, the threshold for functional measurement. Content deemed to encourage self-harm, such as eating disorders, was just as minimal, and rule violations for bullying and harassment occurred in just eight of 10,000 views. 

“There’s a grading-your-own-homework problem,”

Meta defines what constitutes harmful content, so it shapes the discussion of how successful it is at dealing with it.”

It could reconsider its AI-generated “beauty filters,” which internal research suggested made both the people who used them and those who viewed the images more self-critical

the team built a new questionnaire called BEEF, short for “Bad Emotional Experience Feedback.

A recurring survey of issues 238,000 users had experienced over the past seven days, the effort identified problems with prevalence from the start: Users were 100 times more likely to tell Instagram they’d witnessed bullying in the last week than Meta’s bullying-prevalence statistics indicated they should.

“People feel like they’re having a bad experience or they don’t,” one presentation on BEEF noted. “Their perception isn’t constrained by policy.

they seemed particularly common among teens on Instagram.

Among users under the age of 16, 26% recalled having a bad experience in the last week due to witnessing hostility against someone based on their race, religion or identity

More than a fifth felt worse about themselves after viewing others’ posts, and 13% had experienced unwanted sexual advances in the past seven days. 

The vast gap between the low prevalence of content deemed problematic in the company’s own statistics and what users told the company they experienced suggested that Meta’s definitions were off, Bejar argued

To minimize content that teenagers told researchers made them feel bad about themselves, Instagram could cap how much beauty- and fashion-influencer content users saw.

Proving to Meta’s leadership that the company’s prevalence metrics were missing the point was going to require data the company didn’t have. So Bejar and a group of staffers from the Well-Being Team started collecting it

And it could build ways for users to report unwanted contacts, the first step to figuring out how to discourage them.

One experiment run in response to BEEF data showed that when users were notified that their comment or post had upset people who saw it, they often deleted it of their own accord. “Even if you don’t mandate behaviors,” said Krieger, “you can at least send signals about what behaviors aren’t welcome.”

But among the ranks of Meta’s senior middle management, Bejar and Krieger said, BEEF hit a wall. Managers who had made their careers on incrementally improving prevalence statistics weren’t receptive to the suggestion that the approach wasn’t working. 

After three decades in Silicon Valley, he understood that members of the company’s C-Suite might not appreciate a damning appraisal of the safety risks young users faced from its product—especially one citing the company’s own data. 

“This was the email that my entire career in tech trained me not to send,” he says. “But a part of me was still hoping they just didn’t know.”

“Policy enforcement is analogous to the police,” he wrote in the email Oct. 5, 2021—arguing that it’s essential to respond to crime, but that it’s not what makes a community safe. Meta had an opportunity to do right by its users and take on a problem that Bejar believed was almost certainly industrywide.

fter Haugen’s airing of internal research, Meta had cracked down on the distribution of anything that would, if leaked, cause further reputational damage. With executives privately asserting that the company’s research division harbored a fifth column of detractors, Meta was formalizing a raft of new rules for employees’ internal communication.

Among the mandates for achieving “Narrative Excellence,” as the company called it, was to keep research data tight and never assert a moral or legal duty to fix a problem.

“I had to write about it as a hypothetical,” Bejar said. Rather than acknowledging that Instagram’s survey data showed that teens regularly faced unwanted sexual advances, the memo merely suggested how Instagram might help teens if they faced such a problem.

The hope that the team’s work would continue didn’t last. The company stopped conducting the specific survey behind BEEF, then laid off most everyone who’d worked on it as part of what Zuckerberg called Meta’s “year of efficiency.

If Meta was to change, Bejar told the Journal, the effort would have to come from the outside. He began consulting with a coalition of state attorneys general who filed suit against the company late last month, alleging that the company had built its products to maximize engagement at the expense of young users’ physical and mental health. Bejar also got in touch with members of Congress about where he believes the company’s user-safety efforts fell short. 

The contrary insistence that the glories of art and thought are not evolutionary adaptations, or that the mind is not the brain, or that love is not just biology’s bait for sex, now amounts to a kind of heresy.

Greif’s book is a prehistory of our predicament, of our own “crisis of man.” (The “man” is archaic, the “crisis” is not.) It recognizes that the intellectual history of modernity may be written in part as the epic tale of a series of rebellions against humanism

We are not becoming transhumanists, obviously. We are too singular for the Singularity. But are we becoming posthumanists?

In American culture right now, as I say, the worldview that is ascendant may be described as posthumanism.

The posthumanism of the 1970s and 1980s was more insular, an academic affair of “theory,” an insurgency of professors; our posthumanism is a way of life, a social fate.

In “The Age of the Crisis of Man: Thought and Fiction in America, 1933-1973,” the gifted essayist Mark Greif, who reveals himself to be also a skillful historian of ideas, charts the history of the 20th-century reckonings with the definition of “man.

Here is his conclusion: “Anytime your inquiries lead you to say, ‘At this moment we must ask and decide who we fundamentally are, our solution and salvation must lie in a new picture of ourselves and humanity, this is our profound responsibility and a new opportunity’ — just stop.” Greif seems not to realize that his own book is a lasting monument to precisely such inquiry, and to its grandeur

“Answer, rather, the practical matters,” he counsels, in accordance with the current pragmatist orthodoxy. “Find the immediate actions necessary to achieve an aim.” But before an aim is achieved, should it not be justified? And the activity of justification may require a “picture of ourselves.” Don’t just stop. Think harder. Get it right.

— but rather in the appeal to their defiantly nonutilitarian character, so that individuals can know more than how things work, and develop their powers of discernment and judgment, their competence in matters of truth and goodness and beauty, to equip themselves adequately for the choices and the crucibles of private and public life.

Who has not felt superior to humanism? It is the cheapest target of all: Humanism is sentimental, flabby, bourgeois, hypocritical, complacent, middlebrow, liberal, sanctimonious, constricting and often an alibi for power

what is humanism? For a start, humanism is not the antithesis of religion, as Pope Francis is exquisitely demonstrating

The worldview takes many forms: a philosophical claim about the centrality of humankind to the universe, and about the irreducibility of the human difference to any aspect of our animality

Here is a humanist proposition for the age of Google: The processing of information is not the highest aim to which the human spirit can aspire, and neither is competitiveness in a global economy. The character of our society cannot be determined by engineers.

And posthumanism? It elects to understand the world in terms of impersonal forces and structures, and to deny the importance, and even the legitimacy, of human agency.

There have been humane posthumanists and there have been inhumane humanists. But the inhumanity of humanists may be refuted on the basis of their own worldview

the condemnation of cruelty toward “man the machine,” to borrow the old but enduring notion of an 18th-century French materialist, requires the importation of another framework of judgment. The same is true about universalism, which every critic of humanism has arraigned for its failure to live up to the promise of a perfect inclusiveness

there has never been a universalism that did not exclude. Yet the same is plainly the case about every particularism, which is nothing but a doctrine of exclusion; and the correction of particularism, the extension of its concept and its care, cannot be accomplished in its own name. It requires an idea from outside, an idea external to itself, a universalistic idea, a humanistic idea.

Asking universalism to keep faith with its own principles is a perennial activity of moral life. Asking particularism to keep faith with its own principles is asking for trouble.

there is no more urgent task for American intellectuals and writers than to think critically about the salience, even the tyranny, of technology in individual and collective life

a methodological claim about the most illuminating way to explain history and human affairs, and about the essential inability of the natural sciences to offer a satisfactory explanation; a moral claim about the priority, and the universal nature, of certain values, not least tolerance and compassion

“Our very mastery seems to escape our mastery,” Michel Serres has anxiously remarked. “How can we dominate our domination; how can we master our own mastery?”

universal accessibility is not the end of the story, it is the beginning. The humanistic methods that were practiced before digitalization will be even more urgent after digitalization, because we will need help in navigating the unprecedented welter

Searches for keywords will not provide contexts for keywords. Patterns that are revealed by searches will not identify their own causes and reasons

The new order will not relieve us of the old burdens, and the old pleasures, of erudition and interpretation.

Is all this — is humanism — sentimental? But sentimentality is not always a counterfeit emotion. Sometimes sentiment is warranted by reality.

The persistence of humanism through the centuries, in the face of formidable intellectual and social obstacles, has been owed to the truth of its representations of our complexly beating hearts, and to the guidance that it has offered, in its variegated and conflicting versions, for a soulful and sensitive existence

a complacent humanist is a humanist who has not read his books closely, since they teach disquiet and difficulty. In a society rife with theories and practices that flatten and shrink and chill the human subject, the humanist is the dissenter.

Guillaume Lancereau, Max Weber fellow at the European University Institute in Florence, was part of a group of historians who published the book Puy du Faux (Puy of Fakes), analysing the park’s take on history. They viewed the park as having a Catholic slant, questionable depictions of nobility and a presentation of rural peasants as unchanged through the ages.

Lancereau did not question the park’s entertainment value. But he said: “Professional historians have repeatedly criticised the park for taking liberties with historical events and characters and, more importantly, for distorting the past to serve a nationalistic, religious and conservative political agenda. This raises important questions about the contemporary entanglement between entertainment, collective memory and politically oriented historical production …

“At a time when increasing numbers of undergraduates are acquiring their historical knowledge from popular culture and historical reenactments, the Puy du Fou’s considerable expansion calls for further investigation of a phenomenon that appears to be influencing the making of historical memory in contemporary Europe.”

Outside the park’s musketeers show, André, 76, had driven 650km (400 miles) from Burgundy with his wife and grandson. “We came because we’re interested in history,” he said. “The shows are technically brilliant and really make you think. You can tell it’s a bit on the right – the focus on war, warriors and anti-revolution – but I don’t think that matters.”

Though Hoover’s settings bop around America from Boston to New York to Texas to Vermont, the only contextual references pertain to pop culture, social media and the occasional local attraction.

Politics are confined to the daunting gulf between haves and have-nots, and even when Hoover’s striving heroines find themselves among the haves, their hearts remain forever with the have-nots.

In these novels what matters more than anything else is hardship: Hardship is everywhere, women must suffer, women can heal, and those who make it through all this have the capacity to find themselves/love/happiness. The reader can’t help feeling that the heroine/Hoover is speaking to me/for me/like me.

Fiction of this sort reflects a strain in the culture that has shifted from a fascination with the other — the rich, the powerful, the exclusive — to a more inward preoccupation with the self and the desire to see oneself reflected in the stories one consumes

Women’s popular fiction of the ’80s, when the glitter and glamour of “Dallas” and “Dynasty” dominated prime-time TV, offers a sharp contrast. In best sellers of that period, the settings jetted from Monte Carlo to Capri to Rodeo Drive, populated by the rich, famous and destined-to-be. Heroines could have been peeled off the cover of Cosmopolitan magazine

As with TikTok testimonials of adolescent mental health challenges and group-chat confessions, it’s about “relatability” and the willingness to reveal all. Even celebrities must bare all

I never shed a tear while reading Sheldon, but that wasn’t the point. The point was exuberant voyeurism, the literary equivalent of “Lifestyles of the Rich and Famous.” The heroines’ lives were nothing like mine nor were they meant to be. That’s what made them so absurdly entertaining.

Colleen Hoover paints on a more intimate canvas. Her stories aren’t about attaining worldly power on a grand scale, but about finding power within

Hoover offers readers an emotional road map to recovery from imposter syndrome, domestic abuse, betrayal, victimization. It’s a very different kind of achievement.

In a country where economic inequalities can seem insurmountable and systems of power ever more remote, this may be the best her hard-knock heroines — and readers — can hope for.

For readers invested in characters who are like themselves — if perhaps more beautiful and with more exciting sex lives — the emotional payoff can still feel hard-earned. And, just possibly, the story could happen to them.

Social-media platforms are “preying on your insecurities; they’re preying on your temptations,” Jenn explained to me in an interview that shifted our parasocial connection, at least for an hour, to a mere relationship. “And, you know, I do play a role in this.” Jenn makes money through aspirational advertising, after all—a familiar part of any influencer’s job.

She’s pro–parasocial relationships, she explains to the camera, but only if we remain aware that we’re in one. “This relationship does not replace existing friendships, existing relationships,” she emphasizes. “This is all supplementary. Like, it should be in addition to your life, not a replacement.” I sat there watching her talk about parasocial relationships while absorbing the irony of being in one with her.

The open acknowledgment of social media’s inner workings, with content creators exposing the foundations of their content within the content itself, is what Alice Marwick, an associate communications professor at the University of North Carolina at Chapel Hill, described to me as “meta-content.”

Meta-content can be overt, such as the vlogger Casey Neistat wondering, in a vlog, if vlogging your life prevents you from being fully present in it;

But meta-content can also be subtle: a vlogger walking across the frame before running back to get the camera. Or influencers vlogging themselves editing the very video you’re watching, in a moment of space-time distortion.

Viewers don’t seem to care. We keep watching, fully accepting the performance. Perhaps that’s because the rise of meta-content promises a way to grasp authenticity by acknowledging artifice; especially in a moment when artifice is easier to create than ever before, audiences want to know what’s “real” and what isn’

“The idea of a space where you can trust no sources, there’s no place to sort of land, everything is put into question, is a very unsettling, unsatisfying way to live.

So we continue to search for, as Murray observes, the “agreed-upon things, our basic understandings of what’s real, what’s true.” But when the content we watch becomes self-aware and even self-critical, it raises the question of whether we can truly escape the machinations of social media. Maybe when we stare directly into the abyss, we begin to enjoy its company.

“The difference between BeReal and the social-media giants isn’t the former’s relationship to truth but the size and scale of its deceptions.” BeReal users still angle their camera and wait to take their daily photo at an aesthetic time of day. The snapshots merely remind us how impossible it is to stop performing online.

Jenn’s concern over the future of the internet stems, in part, from motherhood. She recently had a son, Lennon (whose first birthday party I watched on YouTube), and worries about the digital world he’s going to inherit.

Back in the age of MySpace, she had her own internet friends and would sneak out to parking lots at 1 a.m. to meet them in real life: “I think this was when technology was really used as a tool to connect us.” Now, she explained, it’s beginning to ensnare us. Posting content online is no longer a means to an end so much as the end itself.

We used to view influencers’ lives as aspirational, a reality that we could reach toward. Now both sides acknowledge that they’re part of a perfect product that the viewer understands is unattainable and the influencer acknowledges is not fully real.

“I forgot to say this to her in the interview, but I truly think that my videos are less about me and more of a reflection of where you are currently … You are kind of reflecting on your own life and seeing what resonates [with] you, and you’re discarding what doesn’t. And I think that’s what’s beautiful about it.”

meta-content is fundamentally a compromise. Recognizing the delusion of the internet doesn’t alter our course within it so much as remind us how trapped we truly are—and how we wouldn’t have it any other way.

Before the introduction of Botox and hyaluronic acid dermal fillers in 2002 and 2003, respectively, aesthetic work was serious, expensive. Nose jobs and face lifts required general anesthesia, not insignificant recovery time, and cost thousands of dollars (in 2000, a facelift was $5,416 on average, and a rhinoplasty $4,109, around $9,400 and $7,000 adjusted).

In contrast, the average price of a syringe of hyaluronic acid filler today is $684, while treating, for example, the forehead and eyes with Botox will put you out anywhere from $300 to $600

We copied the beautiful and the rich, not in facsimile, but in homage.

In 2018, use of Botox and fillers was up 18% and 20% from five years prior. Philosophies of prejuvenation have made Botox use jump 22% among 22- to 37-year-olds in half a decade as well. By 2030, global noninvasive aesthetic treatments are predicted to triple.

The trouble is that a status symbol, without status, is common.

Beauty has always been exclusive. When someone strikes you as pretty, it means they are something that everyone else is not.

It’s a zero-sum game, as relative as our morals. Naturally, we hoard of beauty what we can. It’s why we call grooming tips “secrets.”

Largely the secrets started with the wealthy, who possess the requisite money and leisure to spare on their appearances

Botox and filler only accelerated a trend that began in the ’70s and ’80s and is just now reaching its saturation point.

we didn’t have the tools for anything more than emulation. Fake breasts and overdrawn lips only approximated real ones; a birthmark drawn with pencil would always be just that.

Instagram Face, on the other hand, distinguishes itself by its sheer reproducibility. Not only because of those new cosmetic technologies, which can truly reshape features, at reasonable cost and with little risk.

built in to the whole premise of reversible, low-stakes modification is an indefinite flux, and thus a lack of discretion.

Instagram Face has replicated outward, with trendsetters giving up competing with one another in favor of looking eerily alike. And obviously it has replicated down.

Eva looks like Eva. If she has procedures in common with Kim K, you couldn’t tell. “I look at my features and I think long and hard of how I can, without looking different and while keeping as natural as possible, make them look better and more proportional. I’m against everything that is too invasive. My problem with Instagram Face is that if you want to look like someone else, you should be in therapy.”

natural looks have always been, and still are, more valuable than artificial ones. Partly because of our urge to legitimize in any way we can the advantages we have over other people. Hotness is a class struggle.

As more and more women post videos of themselves eating, sleeping, dressing, dancing, and Only-Fanning online, in a logical bid for economic ascendance, the women who haven’t needed to do that gain a new status symbol.

Privacy. A life which is not a ticketed show. An intimacy that does not admit advertisers. A face that does not broadcast its insecurity, or the work undergone to correct it.

Upper class, private women get discrete work done. The differences aren’t in the procedures themselves—they’re the same—but in disposition

Eva, who lives between central London, Geneva, and the south of France, says: “I do stuff, but none of the stuff I do is at all in my head associated with Instagram Face. Essentially you do similar procedures, but the end goal is completely different. Because they are trying to get the result of looking like another human being, and I’m just beautifying myself.”

But the more rapidly it replicates, and the clearer our manuals for quick imitation become, the closer we get to singularity—that moment Kim Kardashian fears unlike any other: the moment when it becomes unclear whether we’re copying her, or whether she is copying us.

what he restores is complicated and yet not complicated at all. It’s herself, the fingerprint of her features. Her aura, her presence and genealogy, her authenticity in space and time.

Dr. Taktouk’s approach is “not so formulaic.” He aims to give his patients the “better versions of themselves.” “It’s not about trying to be anyone else,” he says, “or creating a conveyor belt of patients. It’s about working with your best features, enhancing them, but still looking like you.”

“Vulgar” says that in pursuing indistinguishability, women have been duped into another punishing divide. “Vulgar” says that the subtlety of his work is what signals its special class—and that the women who’ve obtained Instagram Face for mobility’s sake have unwittingly shut themselves out of it.

While younger women are dissolving their gratuitous work, the 64-year-old Madonna appeared at the Grammy Awards in early February, looking so tragically unlike herself that the internet launched an immediate postmortem.

The folly of Instagram Face is that in pursuing a bionic ideal, it turns cosmetic technology away from not just the reality of class and power, but also the great, poignant, painful human project of trying to reverse time. It misses the point of what we find beautiful: that which is ephemeral, and can’t be reproduced

Age is just one of the hierarchies Instagram Face can’t topple, in the history of women striving versus the women already arrived. What exactly have they arrived at?

Youth, temporarily. Wealth. Emotional security. Privacy. Personal choices, like cosmetic decisions, which are not so public, and do not have to be defended as empowered, in the defeatist humiliation of our times

Maybe they’ve arrived at love, which for women has never been separate from the things I’ve already mentioned.

I can’t help but recall the time I was chatting with a plastic surgeon. I began to point to my features, my flaws. I asked her, “What would you do to me, if I were your patient?” I had many ideas. She gazed at me, and then noticed my ring. “Nothing,” she said. “You’re already married.”

While people praised Finland’s strong social safety net and spoke glowingly of the psychological benefits of nature and the personal joys of sports or music, they also talked about guilt, anxiety and loneliness. Rather than “happy,” they were more likely to characterize Finns as “quite gloomy,” “a little moody” or not given to unnecessary smiling

Many also shared concerns about threats to their way of life, including possible gains by a far-right party in the country’s elections in April, the war in Ukraine and a tense relationship with Russia, which could worsen now that Finland is set to join NATO.

It turns out even the happiest people in the world aren’t that happy. But they are something more like content.

Finns derive satisfaction from leading sustainable lives and perceive financial success as being able to identify and meet basic need

“In other words,” he wrote in an email, “when you know what is enough, you are happy.”

“‘Happiness,’ sometimes it’s a light word and used like it’s only a smile on a face,” Teemu Kiiski, the chief executive of Finnish Design Shop, said. “But I think that this Nordic happiness is something more foundational.”

e conventional wisdom is that it’s easier to be happy in a country like Finland where the government ensures a secure foundation on which to build a fulfilling life and a promising future. But that expectation can also create pressure to live up to the national reputation.

“We are very privileged and we know our privilege,” said Clara Paasimaki, 19, one of Ms. Hansen’s students in Kokkola, “so we are also scared to say that we are discontent with anything, because we know that we have it so much better than other people,” especially in non-Nordic countries.

“The fact that Finland has been ‘the happiest country on earth’ for six years in a row could start building pressure on people,” he wrote in an email. “If we Finns are all so happy, why am I not happy?

The Finnish way of life is summed up in “sisu,” a trait said to be part of the national character. The word roughly translates to “grim determination in the face of hardships,” such as the country’s long winters: Even in adversity, a Finn is expected to persevere, without complaining.

“Back in the day when it wasn’t that easy to survive the winter, people had to struggle, and then it’s kind of been passed along the generations,” said Ms. Paasimaki’s classmate Matias From, 18. “Our parents were this way. Our grandparents were this way. Tough and not worrying about everything. Just living life.”

Since immigrating from Zimbabwe in 1992, Julia Wilson-Hangasmaa, 59, has come to appreciate the freedom Finland affords people to pursue their dreams without worrying about meeting basic needs

When she returns to her home country, she is struck by the “good energy” that comes not from the satisfaction of sisu but from exuberant joy.

“What I miss the most, I realize when I enter Zimbabwe, are the smiles,” she said, among “those people who don’t have much, compared to Western standards, but who are rich in spirit.”

Many of our subjects cited the abundance of nature as crucial to Finnish happiness: Nearly 75 percent of Finland is covered by forest, and all of it is open to everyone thanks to a law known as “jokamiehen oikeudet,” or “everyman’s right,” that entitles people to roam freely throughout any natural areas, on public or privately owned land.

“I enjoy the peace and movement in nature,” said Helina Marjamaa, 66, a former track athlete who represented the country at the 1980 and 1984 Olympic Games. “That’s where I get strength. Birds are singing, snow is melting, and nature is coming to life. It’s just incredibly beautiful.”

“I am worried with this level of ignorance we have toward our own environment,” he said, citing endangered species and climate change. The threat, he said, “still doesn’t seem to shift the political thinking.”

Born 17 years after Finland won independence from Russia, Eeva Valtonen has watched her homeland transform: from the devastation of World War II through years of rebuilding to a nation held up as an exemplar to the world.

“My mother used to say, ‘Remember, the blessing in life is in work, and every work you do, do it well,’” Ms. Valtonen, 88, said. “I think Finnish people have been very much the same way. Everybody did everything together and helped each other.”

Maybe it isn’t that Finns are so much happier than everyone else. Maybe it’s that their expectations for contentment are more reasonable, and if they aren’t met, in the spirit of sisu, they persevere.

“We don’t whine,” Ms. Eerikainen said. “We just do.”

“The Fallout universe lends itself really well to Shakespeare. It’s very desolate, very grotesque, very tragic, really,” says North. In this world, Shakespeare existed before the bombs fell, so it seemed logical that North and his friends could role-play a company keeping culture alive in the ruins of civilisation – like the troupe of actors in Emily St John Mandel’s post-apocalyptic dystopia, Station Eleven.

It takes months to pull a show together. First, North picks the play and adapts it. Hundreds of pages of script are shared with the crew, so set design and rehearsals can commence. “It’s just like a real theatre company, where you start with an idea and a few folks sitting together and figuring out what our season is going to look like,”

There are no ticketed seats, and the company makes no money. The majority of audiences stumble across the performances accidentally in the wasteland, and sit to watch the show for free – or tune in on Twitch, where the company broadcasts every performance live

n 2022 Fallout 76 claimed to have over 13.5 million players, some of whom North believes “may never have seen a Shakespeare play. Ninety-nine per cent of those who find us sit down and quietly watch the show … It’s really quite moving, performing for people who might not go to the theatre in their own communities or haven’t thought about Shakespeare since high school. We are tickled silly knowing that we are potentially reaching new, untapped audiences and (re)introducing Shakespeare to so many. I hope Shakespeare academics who study comparative drama will take note of our use of this new medium to reach new audiences

“I think we’re a perfect example of how video games inspire creativity, and celebrate theatre and culture and the arts. I hope that other gamers out there know that there’s so much potential for you to be able to express what you’re passionate about in video games.”

Like all of these books, it is about the power and untrustworthiness of written texts—history texts in particular. These various strands don’t always cohere. The question of who killed Bonkowski Pasha is part of the main story of the novel, and yet it disappears for chapters at a time. Perhaps more seriously, the postmodern elements sometimes sit uncomfortably with the torrents of historical and sensory detail

Making friends can be hard—but there may be more opportunities than we think. Doing these interviews has taught me that connection can come from anywhere, at any time, if both parties are open to it.

“You have to look for friendship in places you would never expect it.”

Paying attention goes a long way when forging these unexpected friendships—noticing when you click with someone, being open to chance encounters.

as much as we may feel like our social networks are set and settled, it’s never too late to meet someone who will be important to you for the rest of your life. I spoke with more than one group who was surprised and grateful to have found one another in middle age, a period when work and family responsibilities tend to peak and keeping up with friends is not always easy.

I’m inspired by the people I’ve spoken with who imagined something different for themselves: the friends who bought a house together, who went to therapy together, who have raised their children together, who committed to an “arranged friendship,” whose friendship has fueled their fight for justice.

they won’t grow without intention. This is the hardest part of friendship. It takes energy and thought, and our mental and physical resources are often spread thin. In other words, friendships take work. But I have never liked framing our friendships as labor. Showing up for our friends takes effort, yes, but it shouldn’t be drudgery. It should be a joy.

One thing that seems to make keeping up with friends easier is ritual. I personally find that the effort of coordinating hangs (or even phone calls) is the biggest barrier to seeing my friends. It’s much easier when something is baked into my schedule, and all I have to do is show up.

Some have organized a book club, a monthly hike, or a regular dinner party. Others have committed to a group chat that runs all day every day, or a Dungeons & Dragons campaign that’s lasted for 30 years. In addition to keeping groups close, these traditions can fuel a friendship and give it a shared culture.

Imagination

Society has a place for friendships, and it’s on the sidelines. They’re supposed to play a supporting role to work, family, and romance. It takes imagination not to default to this norm, and to design your life so that friendship plays the role you really want it to.

Attention only gets you so far without action. When opportunity arises, you have to put yourself out there, and that requires courage, vulnerability, and a willingness to let things be awkward.

The man who gave his friend a kidney and the woman who gave birth to her best friend’s quadruplets remind me that there are friends who choose to love each other radically every day. Their love does not stand on the sidelines.

The beauty and the challenge of friendship is its diversity. A friendship can be whatever you want it to. Each one is a canvas whose only limit is our imagination.

Grace

All of the forces I’ve mentioned so far—accumulation, attention, intention, ritual, and imagination—are ideals. They’re impossible to fully live up to. Life often gets in the way.

I do love the concept of grace, of a gift so profound that it could never be earned or deserved. And so when I cite grace here as the final and most important force in friendships, I mean it in two ways. One is the forgiveness that we offer each other when we fall short. The other is the space that creates for connections—and reconnections—that feel nothing short of miraculous.

Many of the people I spoke with—who, in many cases, love each other so much that they nominated themselves to be interviewed about their friendship—told me that they don’t see each other that often, or that they don’t talk as much as they would like. I’ve come to believe that friendship doesn’t always have to be about presence; it can also be about love that can weather absence.

Sometimes, people have assumed that I must be a really great friend, given how much time I’ve spent thinking about this. And I’m not. I try to be, but I tend to retreat too much into myself and my romantic relationship and don’t prioritize my friends as much as I’d like to.

But absence doesn’t have to last forever. “The Friendship Files” includes many stories of second chances and rekindlings.

Accumulation

Attention

Intention

Ritual

C is to collect a lot of information. Thirty years ago, the challenge was finding information in a card catalog at the library. Now it's, how do we separate the good stuff from the bad stuff?

A is to analyze both sides. Lawyers have to turn the coin over and exhaust counterarguments or we'll lose in court.

So lawyers are trained to look for the gray areas, to look for the questions are not the answers. And if we kind of orient our thinking that way, I think we're less likely to shut down competing points of view.

My argument in the book is, we can feel good about a decision even if we don't get everything that we want. We have to make compromises.

I tell my students, you'll get through the bar. The key is to look for questions and not answers. If you could answer every legal question with a Wikipedia search, there would be no reason to hire lawyers.

Lawyers are hired because there are arguments on both sides, you know? Every Supreme Court decision that is split 6-3, 5-4, that means there were really strong arguments on both sides.

T is, tolerate the fact that you won't get everything you want every time

So we have to be very careful about the source of what you're getting, OK? Is this source neutral? Is this source really care about facts and not so much about an agenda?

Step 3, the collecting information piece. I think it's a new skill for all of us that we are overloaded with information into our phones. We have algorithms that somebody else developed that tailor the information that comes into our phones based on what the computer thinks we already believe

No. 2 - this is the beauty of social media and the internet - you can pull original sources. We can click on the indictment. Click on the new bill that has been proposed in the United States Congress.

then the book explains ways that you can then sort through that information for yourself. Skills are empowering.

Maybe as a replacement for sort of being empowered by being part of a team - a red team versus a blue team - that's been corrosive, I think, in American politics and American society. But arming ourselves with good facts, that leads to self-determination.

MARTINEZ: Now, you've written two other books - "How To Read The Constitution" and "What You Need To Know About Voting" - along with this one, "How To Think Like A Lawyer - And Why.

It kind of makes me think, Kim, that you feel that Americans might be lacking a basic level of civics education or understanding. So what is lacking when it comes to teaching civics or in civics discourse today?

studies have shown that around a third of Americans can't name the three branches of government. But if we don't understand our government, we don't know how to hold our government accountable

Democracies can't stay open if we've got elected leaders that are caring more about entrenching their own power and misinformation than actually preserving democracy by the people. I think that's No. 1.

No. 2 has to do with a value system. We talk about American values - reward for hard work, integrity, honesty. The same value system should apply to who we hire for government positions. And I think Americans have lost that.

in my own life, I'm very careful about who gets to be part of the inner circle because I have a strong value system. Bring that same sense to bear at the voting booth. Don't vote for red versus blue. Vote for people that live your value system

just like the Ukrainians are fighting for their children's democracy, we need to do that as well. And we do that through informing ourselves with good information, tolerating competing points of view and voting - voting, voting, voting - to hold elected leaders accountable if they cross boundaries that matter to us in our own lives.

It isn’t clear how the American public-school system will survive the COVID years. Teachers, whose relative pay and status have been in decline for decades, are fleeing the field. In 2021, buckling under the stresses of the pandemic, nearly 1 million people quit jobs in public education, a 40 percent increase over the previous year.

These kids, and the investments that come with them, may never return—the beginning of a cycle of attrition that could continue long after the pandemic ends and leave public schools even more underfunded and dilapidated than before. “It’s an open question whether the public-school system will recover,” Steiner said. “That is a real concern for democratic education.”

The high-profile failings of public schools during the pandemic have become a political problem for Democrats, because of their association with unions, prolonged closures, and the pedagogy of social justice, which can become a form of indoctrination.

The party that stands for strong government services in the name of egalitarian principles supported the closing of schools far longer than either the science or the welfare of children justified, and it has been woefully slow to acknowledge how much this damaged the life chances of some of America’s most disadvantaged students.

Public education is too important to be left to politicians and ideologues. Public schools still serve about 90 percent of children across red and blue America.

Since the common-school movement in the early 19th century, the public school has had an exalted purpose in this country. It’s our core civic institution—not just because, ideally, it brings children of all backgrounds together in a classroom, but because it prepares them for the demands and privileges of democratic citizenship. Or at least, it needs to.

What is school for? This is the kind of foundational question that arises when a crisis shakes the public’s faith in an essential institution. “The original thinkers about public education were concerned almost to a point of paranoia about creating self-governing citizens,”

“Horace Mann went to his grave having never once uttered the phrase college- and career-ready. We’ve become more accustomed to thinking about the private ends of education. We’ve completely lost the habit of thinking about education as citizen-making.”

School can’t just be an economic sorting system. One reason we have a stake in the education of other people’s children is that they will grow up to be citizens.

Public education is meant not to mirror the unexamined values of a particular family or community, but to expose children to ways that other people, some of them long dead, think.

If the answer were simply to push more and more kids into college, the United States would be entering its democratic prime

So the question isn’t just how much education, but what kind. Is it quaint, or utopian, to talk about teaching our children to be capable of governing themselves?

The COVID era, with Donald Trump out of office but still in power and with battles over mask mandates and critical race theory convulsing Twitter and school-board meetings, shows how badly Americans are able to think about our collective problems—let alone read, listen, empathize, debate, reconsider, and persuade in the search for solutions.

democratic citizenship can, at least in part, be learned.

The history warriors build their metaphysics of national good or evil on a foundation of ignorance. In a 2019 survey, only 40 percent of Americans were able to pass the test that all applicants for U.S. citizenship must take, which asks questions like “Who did the United States fight in World War II?” and “We elect a President for how many years?” The only state in which a majority passed was Vermont.

he orthodoxies currently fighting for our children’s souls turn the teaching of U.S. history into a static and morally simple quest for some American essence. They proceed from celebration or indictment toward a final judgment—innocent or guilty—and bury either oppression or progress in a subordinate clause. The most depressing thing about this gloomy pedagogy of ideologies in service to fragile psyches is how much knowledge it takes away from students who already have so little

A central goal for history, social-studies, and civics instruction should be to give students something more solid than spoon-fed maxims—to help them engage with the past on its own terms, not use it as a weapon in the latest front of the culture wars.

Releasing them to do “research” in the vast ocean of the internet without maps and compasses, as often happens, guarantees that they will drown before they arrive anywhere.

The truth requires a grounding in historical facts, but facts are quickly forgotten without meaning and context

The goal isn’t just to teach students the origins of the Civil War, but to give them the ability to read closely, think critically, evaluate sources, corroborate accounts, and back up their claims with evidence from original documents.

This kind of instruction, which requires teachers to distinguish between exposure and indoctrination, isn’t easy; it asks them to be more sophisticated professionals than their shabby conditions and pay (median salary: $62,000, less than accountants and transit police) suggest we are willing to support.

To do that, we’ll need to help kids restore at least part of their crushed attention spans.

staring at a screen for hours is a heavy depressant, especially for teenagers.

we’ll look back on the amount of time we let our children spend online with the same horror that we now feel about earlier generations of adults who hooked their kids on smoking.

“It’s not a choice between tech or no tech,” Bill Tally, a researcher with the Education Development Center, told me. “The question is what tech infrastructure best enables the things we care about,” such as deep engagement with instructional materials, teachers, and other students.

The pandemic should have forced us to reassess what really matters in public school; instead, it’s a crisis that we’ve just about wasted.

Like learning to read as historians, learning to sift through the tidal flood of memes for useful, reliable information can emancipate children who have been heedlessly hooked on screens by the adults in their lives

Finally, let’s give children a chance to read books—good books. It’s a strange feature of all the recent pedagogical innovations that they’ve resulted in the gradual disappearance of literature from many classrooms.

The best way to interest young people in literature is to have them read good literature, and not just books that focus with grim piety on the contemporary social and psychological problems of teenagers.

We sell them insultingly short in thinking that they won’t read unless the subject is themselves. Mirrors are ultimately isolating; young readers also need windows, even if the view is unfamiliar, even if it’s disturbing

connection through language to universal human experience and thought is the reward of great literature, a source of empathy and wisdom.

The culture wars, with their atmosphere of resentment, fear, and petty faultfinding, are hostile to the writing and reading of literature.

W. E. B. Du Bois wrote: “Nations reel and stagger on their way; they make hideous mistakes; they commit frightful wrongs; they do great and beautiful things. And shall we not best guide humanity by telling the truth about all this, so far as the truth is ascertainable?”

The classroom has become a half-abandoned battlefield, where grown-ups who claim to be protecting students from the virus, from books, from ideologies and counter-ideologies end up using children to protect themselves and their own entrenched camps.

American democracy can’t afford another generation of adults who don’t know how to talk and listen and think. We owe our COVID-scarred children the means to free themselves from the failures of the past and the present.

Students are leaving as well. Since 2020, nearly 1.5 million children have been removed from public schools to attend private or charter schools or be homeschooled.

“COVID has encouraged poor parents to question the quality of public education. We are seeing diminished numbers of children in our public schools, particularly our urban public schools.” In New York, more than 80,000 children have disappeared from city schools; in Los Angeles, more than 26,000; in Chicago, more than 24,000.

He blamed television, above all, for the decline in hobbies, avocations and lifelong education — activities that blend aspects of work and play and, he said, offer the best opportunity for flow and, through it, happiness.

Some critics said his finger pointing smacked of snobbery, to which he had a response: “If holding that everyone should have a chance to get the highest quality of experience is an elitist notion, so be it,” he wrote in a guest essay for The New York Times in 1993. “It is better than resigning oneself to a life of mindless entertainment.”

“We can’t afford to become trapped within ourselves, our jobs, and religions, and lose sight of the entire tapestry of life,” he said in a 1995 interview with Omni magazine. “When the self loses itself in a transcendent purpose — whether to write great poetry, craft beautiful furniture, understand the motions of galaxies, or help children be happier — the self becomes largely invulnerable to the fears and setbacks of ordinary existence.”

Messenger RNA is a powerful, if fickle, component of life’s building blocks — a workhorse of the cell that is also truly just a messenger, unstable and prone to degrade.

. In 1990,

That same year, a team at the University of Wisconsin startled the scientific world with a paper that showed it was possible to inject a snippet of messenger RNA into mice and turn their muscle cells into factories, creating proteins on demand.

If custom-designed RNA snippets could be used to turn cells into bespoke protein factories, messenger RNA could become a powerful medical tool. It could encode fragments of virus to teach the immune system to defend against pathogens. It could also create whole proteins that are missing or damaged in people with devastating genetic diseases, such as cystic fibrosis.

In 2005, the pair discovered a way to modify RNA, chemically tweaking one of the letters of its code, so it didn’t trigger an inflammatory response. Deborah Fuller, a scientist who works on RNA and DNA vaccines at the University of Washington, said that work deserves a Nobel Prize.

messenger RNA posed a bigger challenge than other targets.“It’s tougher — it’s a much bigger molecule, it’s much more unstable,”

Unlike fields that were sparked by a single powerful insight, Sahin said that the recent success of messenger RNA vaccines is a story of countless improvements that turned an alluring biological idea into a beneficial technology.

“This is a field which benefited from hundreds of inventions,” said Sahin, who noted that when he started BioNTech in 2008, he cautioned investors that the technology would not yield a product for at least a decade. He kept his word: Until the coronavirus sped things along, BioNTech projected the launch of its first commercial project in 2023.

“It’s new to you,” Fuller said. “But for basic researchers, it’s been long enough. . . . Even before covid, everyone was talking: RNA, RNA, RNA.”

All vaccines are based on the same underlying idea: training the immune system to block a virus. Old-fashioned vaccines do this work by injecting dead or weakened viruses

ewer vaccines use distinctive bits of the virus, such as proteins on their surface, to teach the lesson. The latest genetic techniques, like messenger RNA, don’t take as long to develop because those virus bits don’t have to be generated in a lab. Instead, the vaccine delivers a genetic code that instructs cells to build those characteristic proteins themselves.

They wanted the immune system to learn to recognize the thumb tack spike, so McLellan tasked a scientist in his laboratory with identifying genetic mutations that could anchor the protein into the right configuration. It was a painstaking process for Nianshuang Wang, who now works at a biotechnology company, Regeneron Pharmaceuticals. After trying hundreds of genetic mutations, he found two that worked. Five journals rejected the finding, questioning its significance, before it was published in 2017.

That infection opened Graham’s eyes to an opportunity. HKU1 was merely a nuisance, as opposed to a deadly pneumonia; that meant it would be easier to work with in the lab, since researchers wouldn’t have to don layers of protective gear and work in a pressurized laboratory.

Severe acute respiratory syndrome had emerged in 2003. Middle East respiratory syndrome (MERS) broke out in 2012. It seemed clear to Graham and Jason McLellan, a structural biologist now at the University of Texas at Austin, that new coronaviruses were jumping into people on a 10-year-clock and it might be time to brace for the next one.

Last winter, when Graham heard rumblings of a new coronavirus in China, he brought the team back together. Once its genome was shared online by Chinese scientists, the laboratories in Texas and Maryland designed a vaccine, utilizing the stabilizing mutations and the knowledge they had gained from years of basic research — a weekend project thanks to the dividends of all that past work.

Graham needed a technology that could deliver it into the body — and had already been working with Moderna, using its messenger RNA technology to create a vaccine against a different bat virus, Nipah, as a dress rehearsal for a real pandemic. Moderna and NIH set the Nipah project aside and decided to go forward with a coronavirus vaccine.

On Jan. 13, Moderna’s Moore came into work and found her team already busy translating the stabilized spike protein into their platform. The company could start making the vaccine almost right away because of its experience manufacturing experimental cancer vaccines, which involves taking tumor samples and developing personalized vaccines in 45 days.

At BioNTech, Sahin said that even in the early design phases of its vaccine candidates, he incorporated the slight genetic changes designed in Graham’s lab that would make the spike look more like the real thing. At least two other companies would incorporate that same spike.

If all goes well with regulators, the coronavirus vaccines have the makings of a pharmaceutical industry fairy tale. The world faced an unparalleled threat, and companies leaped into the fight. Pfizer plowed $2 billion into the effort. Massive infusions of government cash helped remove the financial risks for Moderna.

But the world will also owe their existence to many scientists outside those companies, in government and academia who pursued ideas they thought were important even when the world doubted them

Some of those scientists will receive remuneration, since their inventions are licensed and integrated into the products that could save the world.

As executives become billionaires, many scientists think it is fair to earn money from their inventions that can help them do more important work. But McLellan’s laboratory at the University of Texas is proud to have licensed an even more potent version of their spike protein, royalty-free, to be incorporated into a vaccine for low and middle income countries.

“They’re using the technology that [Kariko] and I developed,” he said. “We feel like it’s our vaccine, and we are incredibly excited — at how well it’s going, and how it’s going to be used to get rid of this pandemic.”

“People hear about [vaccine progress] and think someone just thought about it that night. The amount of work — it’s really a beautiful story of fundamental basic research,” Fauci said. “It was chancy, in the sense that [the vaccine technology] was new. We were aware there would be pushback. The proof in the pudding is a spectacular success.”

The Vaccine Research Center, where Graham is deputy director, was the brainchild of Anthony S. Fauci, director of the National Institute of Allergy and Infectious Diseases. It was created in 1997 to bring together scientists and physicians from different disciplines to defeat diseases, with a heavy focus on HIV.

the pandemic wasn’t a sudden eureka moment — it was a catalyst that helped ignite lines of research that had been moving forward for years, far outside the spotlight of a global crisis.

You might be well-intentioned, rational, and mistaken, simply because so much in our thinking can go wrong. (“RATIONAL, adj.: Devoid of all delusions save those of observation, experience and reflection,”

You might be rational and self-deceptive, because telling yourself that you are rational can itself become a source of bias. It’s possible that you are trying to appear rational only because you want to impress people; or that you are more rational about some things (your job) than others (your kids); or that your rationality gives way to rancor as soon as your ideas are challenged. Perhaps you irrationally insist on answering difficult questions yourself when you’d be better off trusting the expert consensus.

Not just individuals but societies can fall prey to false or compromised rationality. In a 2014 book, “The Revolt of the Public and the Crisis of Authority in the New Millennium,” Martin Gurri, a C.I.A. analyst turned libertarian social thinker, argued that the unmasking of allegedly pseudo-rational institutions had become the central drama of our age: people around the world, having concluded that the bigwigs in our colleges, newsrooms, and legislatures were better at appearing rational than at being so, had embraced a nihilist populism that sees all forms of public rationality as suspect.

modern life would be impossible without those rational systems; we must improve them, not reject them. We have no choice but to wrestle with rationality—an ideal that, the sociologist Max Weber wrote, “contains within itself a world of contradictions.”

Where others might be completely convinced that G.M.O.s are bad, or that Jack is trustworthy, or that the enemy is Eurasia, a Bayesian assigns probabilities to these propositions. She doesn’t build an immovable world view; instead, by continually updating her probabilities, she inches closer to a more useful account of reality. The cooking is never done.

Rationality is one of humanity’s superpowers. How do we keep from misusing it?

Start with the big picture, fixing it firmly in your mind. Be cautious as you integrate new information, and don’t jump to conclusions. Notice when new data points do and do not alter your baseline assumptions (most of the time, they won’t alter them), but keep track of how often those assumptions seem contradicted by what’s new. Beware the power of alarming news, and proceed by putting it in a broader, real-world context.

Bayesian reasoning implies a few “best practices.”

Keep the cooked information over here and the raw information over there; remember that raw ingredients often reduce over heat

We want to live in a more rational society, but not in a falsely rationalized one. We want to be more rational as individuals, but not to overdo it. We need to know when to think and when to stop thinking, when to doubt and when to trust.

But the real power of the Bayesian approach isn’t procedural; it’s that it replaces the facts in our minds with probabilities.

Applied to specific problems—Should you invest in Tesla? How bad is the Delta variant?—the techniques promoted by rationality writers are clarifying and powerful.

the rationality movement is also a social movement; rationalists today form what is sometimes called the “rationality community,” and, as evangelists, they hope to increase its size.

In “Rationality,” “The Scout Mindset,” and other similar books, irrationality is often presented as a form of misbehavior, which might be rectified through education or socialization.

Greg tells me that, in his business, it’s not enough to have rational thoughts. Someone who’s used to pondering questions at leisure might struggle to learn and reason when the clock is ticking; someone who is good at reaching rational conclusions might not be willing to sign on the dotted line when the time comes. Greg’s hedge-fund colleagues describe as “commercial”—a compliment—someone who is not only rational but timely and decisive.

You can know what’s right but still struggle to do it.

Following through on your own conclusions is one challenge. But a rationalist must also be “metarational,” willing to hand over the thinking keys when someone else is better informed or better trained. This, too, is harder than it sounds.

For all this to happen, rationality is necessary, but not sufficient. Thinking straight is just part of the work. 

I found it possible to be metarational with my dad not just because I respected his mind but because I knew that he was a good and cautious person who had my and my mother’s best interests at heart.

between the two of us, we had the right ingredients—mutual trust, mutual concern, and a shared commitment to reason and to act.

Intellectually, we understand that our complex society requires the division of both practical and cognitive labor. We accept that our knowledge maps are limited not just by our smarts but by our time and interests. Still, like Gurri’s populists, rationalists may stage their own contrarian revolts, repeatedly finding that no one’s opinions but their own are defensible. In letting go, as in following through, one’s whole personality gets involved.

in truth, it maps out a series of escalating challenges. In search of facts, we must make do with probabilities. Unable to know it all for ourselves, we must rely on others who care enough to know. We must act while we are still uncertain, and we must act in time—sometimes individually, but often together.

The realities of rationality are humbling. Know things; want things; use what you know to get what you want. It sounds like a simple formula.

The real challenge isn’t being right but knowing how wrong you might be.By Joshua RothmanAugust 16, 2021

Writing about rationality in the early twentieth century, Weber saw himself as coming to grips with a titanic force—an ascendant outlook that was rewriting our values. He talked about rationality in many different ways. We can practice the instrumental rationality of means and ends (how do I get what I want?) and the value rationality of purposes and goals (do I have good reasons for wanting what I want?). We can pursue the rationality of affect (am I cool, calm, and collected?) or develop the rationality of habit (do I live an ordered, or “rationalized,” life?).

Weber worried that it was turning each individual into a “cog in the machine,” and life into an “iron cage.” Today, rationality and the words around it are still shadowed with Weberian pessimism and cursed with double meanings. You’re rationalizing the org chart: are you bringing order to chaos, or justifying the illogical?

For Aristotle, rationality was what separated human beings from animals. For the authors of “The Rationality Quotient,” it’s a mental faculty, parallel to but distinct from intelligence, which involves a person’s ability to juggle many scenarios in her head at once, without letting any one monopolize her attention or bias her against the rest.

In “The Rationality Quotient: Toward a Test of Rational Thinking” (M.I.T.), from 2016, the psychologists Keith E. Stanovich, Richard F. West, and Maggie E. Toplak call rationality “a torturous and tortured term,” in part because philosophers, sociologists, psychologists, and economists have all defined it differently

Galef, who hosts a podcast called “Rationally Speaking” and co-founded the nonprofit Center for Applied Rationality, in Berkeley, barely uses the word “rationality” in her book on the subject. Instead, she describes a “scout mindset,” which can help you “to recognize when you are wrong, to seek out your blind spots, to test your assumptions and change course.” (The “soldier mindset,” by contrast, encourages you to defend your positions at any cost.)

Galef tends to see rationality as a method for acquiring more accurate views.

Pinker, a cognitive and evolutionary psychologist, sees it instrumentally, as “the ability to use knowledge to attain goals.” By this definition, to be a rational person you have to know things, you have to want things, and you have to use what you know to get what you want.

Introspection is key to rationality. A rational person must practice what the neuroscientist Stephen Fleming, in “Know Thyself: The Science of Self-Awareness” (Basic Books), calls “metacognition,” or “the ability to think about our own thinking”—“a fragile, beautiful, and frankly bizarre feature of the human mind.”

A successful student uses metacognition to know when he needs to study more and when he’s studied enough: essentially, parts of his brain are monitoring other parts.

In everyday life, the biggest obstacle to metacognition is what psychologists call the “illusion of fluency.” As we perform increasingly familiar tasks, we monitor our performance less rigorously; this happens when we drive, or fold laundry, and also when we think thoughts we’ve thought many times before

The trick is to break the illusion of fluency, and to encourage an “awareness of ignorance.”

metacognition is a skill. Some people are better at it than others. Galef believes that, by “calibrating” our metacognitive minds, we can improve our performance and so become more rational

There are many calibration methods

nowing about what you know is Rationality 101. The advanced coursework has to do with changes in your knowledge.

Most of us stay informed straightforwardly—by taking in new information. Rationalists do the same, but self-consciously, with an eye to deliberately redrawing their mental maps.

The challenge is that news about distant territories drifts in from many sources; fresh facts and opinions aren’t uniformly significant. In recent decades, rationalists confronting this problem have rallied behind the work of Thomas Bayes

So-called Bayesian reasoning—a particular thinking technique, with its own distinctive jargon—has become de rigueur.

the basic idea is simple. When new information comes in, you don’t want it to replace old information wholesale. Instead, you want it to modify what you already know to an appropriate degree. The degree of modification depends both on your confidence in your preëxisting knowledge and on the value of the new data. Bayesian reasoners begin with what they call the “prior” probability of something being true, and then find out if they need to adjust it.

Bayesian reasoning is an approach to statistics, but you can use it to interpret all sorts of new information.

Globally, the numbers can be even worse, and the stakes often higher. “Say a person comes into the hospital in Sierra Leone with a fever and flulike symptoms,” DeRisi says. “After a few days, or a week, they die. What caused that illness? Most of the time, we never find out. Because if the cause isn’t something that we can culture and test for” — like hepatitis, or strep throat — “it basically just stays a mystery.”

It would be better, DeRisi says, to watch for rare cases of mystery illnesses in people, which often exist well before a pathogen gains traction and is able to spread.

Based on a retrospective analysis of blood samples, scientists now know that H.I.V. emerged nearly a dozen times over a century, starting in the 1920s, before it went global.

Zika was a relatively harmless illness before a single mutation, in 2013, gave the virus the ability to enter and damage brain cells.

The beauty of this approach” — running blood samples from people hospitalized all over the world through his system, known as IDseq — “is that it works even for things that we’ve never seen before, or things that we might think we’ve seen but which are actually something new.”

In this scenario, an undiscovered or completely new virus won’t trigger a match but will instead be flagged. (Even in those cases, the mystery pathogen will usually belong to a known virus family: coronaviruses, for instance, or filoviruses that cause hemorrhagic fevers like Ebola and Marburg.)

And because different types of bacteria require specific conditions in order to grow, you also need some idea of what you’re looking for in order to find it.

The same is true of genomic sequencing, which relies on “primers” designed to match different combinations of nucleotides (the building blocks of DNA and RNA).

Even looking at a slide under a microscope requires staining, which makes organisms easier to see — but the stains used to identify bacteria and parasites, for instance, aren’t the same.

The practice that DeRisi helped pioneer to skirt this problem is known as metagenomic sequencing

Unlike ordinary genomic sequencing, which tries to spell out the purified DNA of a single, known organism, metagenomic sequencing can be applied to a messy sample of just about anything — blood, mud, seawater, snot — which will often contain dozens or hundreds of different organisms, all unknown, and each with its own DNA. In order to read all the fragmented genetic material, metagenomic sequencing uses sophisticated software to stitch the pieces together by matching overlapping segments.

The assembled genomes are then compared against a vast database of all known genomic sequences — maintained by the government-run National Center for Biotechnology Information — making it possible for researchers to identify everything in the mix

Traditionally, the way that scientists have identified organisms in a sample is to culture them: Isolate a particular bacterium (or virus or parasite or fungus); grow it in a petri dish; and then examine the result under a microscope, or use genomic sequencing, to understand just what it is. But because less than 2 percent of bacteria — and even fewer viruses — can be grown in a lab, the process often reveals only a tiny fraction of what’s actually there. It’s a bit like planting 100 different kinds of seeds that you found in an old jar. One or two of those will germinate and produce a plant, but there’s no way to know what the rest might have grown into.

Such studies have revealed just how vast the microbial world is, and how little we know about it

“The selling point for researchers is: ‘Look, this technology lets you investigate what’s happening in your clinic, whether it’s kids with meningitis or something else,’” DeRisi said. “We’re not telling you what to do with it. But it’s also true that if we have enough people using this, spread out all around the world, then it does become a global network for detecting emerging pandemics