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Scientists are missing some important bits of data that would help them better understand the effects of gun policy and the causes of gun-related violence. But that’s not the only reason why we don’t have solid answers. Once you have the data, you still have to figure out what it means. This is where the research gets complicated, because the problem isn’t simply about what we do and don’t know right now. The problem, say some scientists, is that we —from the public, to politicians, to even scientists themselves—may be trying to force research to give a type of answer that we can’t reasonably expect it to offer. To understand what science can do for the gun debates, we might have to rethink what “evidence-based policy” means to us.

For the most part, there aren’t a lot of differences in the data that these studies are using. So how can they reach such drastically different conclusions? The issue is in the kind of data that exists, and what you have to do to understand it, says Charles Manski, professor of economics at Northwestern University. Manski studies the ways that other scientists do research and how that research translates into public policy.

Even if we did have those gaps filled in, Manski said, what we’d have would still just be observational data, not experimental data. “We don’t have randomized, controlled experiments, here,” he said. “The only way you could do that, you’d have to assign a gun to some people randomly at birth and follow them throughout their lives. Obviously, that’s not something that’s going to work.”

The Quran, like all foundational religious texts, is a tangle of ambiguities and mysteries, to which endless annotations can be, and are being, written.

So wide was the fame of the 11th-century Baghdad artist Ibn al-Bawwab (“son of the doorman”) that his signature was routinely forged

When a Mongol army laid waste to the city in 1258, his life was spared so that he could work for the new rulers,

I started to wonder about the recipients of our shamings, the real humans who were the virtual targets of these campaigns. So for the past two years, I’ve been interviewing individuals like Justine Sacco: everyday people pilloried brutally, most often for posting some poorly considered joke on social media. Whenever possible, I have met them in person, to truly grasp the emotional toll at the other end of our screens. The people I met were mostly unemployed, fired for their transgressions, and they seemed broken somehow — deeply confused and traumatized.

Read literally, she said that white people don’t get AIDS, but it seems doubtful many interpreted it that way. More likely it was her apparently gleeful flaunting of her privilege that angered people. But after thinking about her tweet for a few seconds more, I began to suspect that it wasn’t racist but a reflexive critique of white privilege — on our tendency to naïvely imagine ourselves immune from life’s horrors. Sacco, like Stone, had been yanked violently out of the context of her small social circle. Right?

“To me it was so insane of a comment for anyone to make,” she said. “I thought there was no way that anyone could possibly think it was literal.” (She would later write me an email to elaborate on this point. “Unfortunately, I am not a character on ‘South Park’ or a comedian, so I had no business commenting on the epidemic in such a politically incorrect manner on a public platform,” she wrote. “To put it simply, I wasn’t trying to raise awareness of AIDS or piss off the world or ruin my life. Living in America puts us in a bit of a bubble when it comes to what is going on in the third world. I was making fun of that bubble.”)

Some have argued that it’s a way to save energy. Others have suggested that slumber provides an opportunity to clear away the brain’s cellular waste. Still others have proposed that sleep simply forces animals to lie still, letting them hide from predators.

It turns out, for example, that neurons can prune their synapses — at least in a dish.

Dr. Diering and his colleagues then searched for the molecular trigger for this change. They found that hundreds of proteins increase or decrease inside of synapses during the night. But one protein in particular, called Homer1A, stood out.

founders from Facebook, Twitter, eBay, Zynga and PayPal, and executives and managers from companies like Google, Microsoft, Cisco and others listened to or participated

they debated whether technology firms had a responsibility to consider their collective power to lure consumers to games or activities that waste time or distract them.

Eric Schiermeyer, a co-founder of Zynga, an online game company and maker of huge hits like FarmVille, has said he has helped addict millions of people to dopamine, a neurochemical that has been shown to be released by pleasurable activities, including video game playing, but also is understood to play a major role in the cycle of addiction. But what he said he believed was that people already craved dopamine and that Silicon Valley was no more responsible for creating irresistible technologies than, say, fast-food restaurants were responsible for making food with such wide appeal. “They’d say: ‘Do we have any responsibility for the fact people are getting fat?’ Most people would say ‘no,’ ” said Mr. Schiermeyer. He added: “Given that we’re human, we already want dopamine.”

the last thing an elite education will teach you is its own inadequacy

I’m talking about the whole system in which these skirmishes play out. Not just the Ivy League and its peer institutions, but also the mechanisms that get you there in the first place: the private and affluent public “feeder” schools, the ever-growing parastructure of tutors and test-prep courses and enrichment programs, the whole admissions frenzy and everything that leads up to and away from it. The message, as always, is the medium. Before, after, and around the elite college classroom, a constellation of values is ceaselessly inculcated.

The first disadvantage of an elite education, as I learned in my kitchen that day, is that it makes you incapable of talking to people who aren’t like you. Elite schools pride themselves on their diversity, but that diversity is almost entirely a matter of ethnicity and race. With respect to class, these schools are largely—indeed increasingly—homogeneous. Visit any elite campus in our great nation and you can thrill to the heartwarming spectacle of the children of white businesspeople and professionals studying and playing alongside the children of black, Asian, and Latino businesspeople and professionals.

In 2005, Michael Ignatieff left a teaching job at Harvard to enter politics in his native Canada

In Parliament, he became a total partisan, putting, as one must, loyalty to the group above loyalty to truth. He had no friends who were not in his own party. He loathed the other side. “We never wasted a single breath trying to convince each other of anything,” he recalls.

He quickly came to understand how politics is different from academia. In academia, you use words to persuade or discover; in politics, you use words to establish a connection. Academia is a cerebral enterprise, but politics is a physical enterprise, a charismatic form of athletics in which you touch people to show you care.In academia, the goal is to come up with a timeless truth. In politics, timing is everything, knowing when the time is ripe for a certain proposal. In academia, the idea is to take a stand based on what you believe; in politics, the idea is to position yourself along a left-right axis in a way that will differentiate you from your opponents and help you win a majority.In academia, a certain false modesty is encouraged; in politics, you have to self-dramatize a fable about yourself — concoct a story to show how your life connects to certain policies. In academia, you are rewarded for candor, intellectual rigor and a willingness to follow an idea to its logical conclusion. In politics, all of these traits are ruinous.

to be a scholar is, often, to be irrelevant.

One reason is the anti-intellectualism in American life

over all, there are, I think, fewer public intellectuals on American university campuses today than a generation ago.

the medical Web, which is dominated by an enormous and powerful site whose name — oh, what the hay, it’s WebMD — has become a panicky byword among laysurfers for “hypochondria time suck.” In more whistle-blowing quarters, WebMD is synonymous with Big Pharma Shilling.

A February 2010 investigation into WebMD’s relationship with drug maker Eli Lilly by Senator Chuck Grassley of Iowa confirmed the suspicions of longtime WebMD users. With the site’s (admitted) connections to pharmaceutical and other companies, WebMD has become permeated with pseudomedicine and subtle misinformation.

WebMD is a corporation that started as an ad-supported health-alarmism site with revenues of $504 million in 2010

Emergence is an important occurrence in social systems ranging in size from small families to large international organizations.

A system is demergent if the whole is less than the sum of its parts, that is, if the interaction of the parts prevents the whole from having valuable properties that it otherwise might have.

My current favorite example of a demergent system is the U.S. Congress, which has many talented people but is failing horribly to pass legislation because of toxic behaviors and interactions.

“Atmosphere: exploring climate change,” the London Science Museum’s exhibit on global warming, is principally sponsored by Shell. You’re asking yourself: Hmm, Shell—isn’t that the name of some trendy “green” startup?

the same old Shell that fills your gas tank and that was responsible for 76 million metric tons of greenhouse gas emissions last year. What could go wrong?

the English-Dutch petroleum behemoth was all too happy to get a little pushy with its suggestions and concerns about the project

If the condescending views of John Cregan about the increasing interest in teaching Latin (Letters, 29 May) are correct, one wonders why the Iris project has had such success in expanding its work across the country and why Barbara Bell’s splendid Latin course for younger children, Minimus, has just exceeded worldwide sales of 150,000.

John Cregan’s description of Latin as “a waste of time” is contradicted by the recent growth of its use in state primary schools;

furthermore his “dead” language remains in evidence all around us

Antoine Louveau was looking through his microscope at thin membranes that protect the brain when he saw something that absolutely shouldn't be there: a lymphatic vessel.

The lymphatic system is part of the circulatory system but, instead of blood, it carries lymph — a clear liquid that ferries immune cells and rids the body of toxins and waste. As a 2009 research review notes, it is "an undisputed anatomical fact" that the brain is the only major organ that lacks a direct connection to the lymphatic system.

The elusive lymphatic vessel hid in plain sight, throughout decades of research, because it was very small and tucked behind a major blood vessel.

Is this a good thing, I wondered, or an epic waste of time?

Twitter devotees at The Times tell me the benefits are real. Twitter enables them to be better reporters, for one thing. By selecting a universe of tweeters to follow, they can track news sources of all kinds, including rival journalists. They can create listening posts across every topic they need to monitor.

I don’t read everything. I dip into Twitter when I have time. The analogy is a cocktail party. You can’t join every conversation, but you drift through the crowd and stop now and then.”

Common readers—which is to say the great majority of people who continue to read—read for one purpose and one purpose only. They read for pleasure. They read to be entertained. They read to be diverted, assuaged, comforted, and tickled.

Reading, where it exists at all, has largely become an unprofitable wing of the diversion industry.

it's not only the division of experience between hard labor and empty leisure that now makes reading for something like mortal stakes a very remote possibility.

Mr. Strom, it turns out, has so little chance of outranking lead gen sites that he’s having a hard time finding a Web consultant to help him fight back. “I told him that it would just be a waste of his money,” says Craig Baerwaldt of Local Inbound Marketing, a search engine expert whom Mr. Strom tried to hire recently. “There are hundreds of these lead gen sites and they spend a ton of money gaming Google.”

because few people search beyond the first page online, snookering Google might be far more effective, especially because many people assume that the company’s algorithm does a bit of consumer-friendly vetting.

Yet if the example of locksmiths is any indication, the horde has the upper hand in certain service sectors, and it all but owns Google Places.

When researchers ask people to assess their own well-being, people in their 20s rate themselves highly. Then there’s a decline as people get sadder in middle age, bottoming out around age 50. But then happiness levels shoot up, so that old people are happier than young people. The people who rate themselves most highly are those ages 82 to 85.

Older people are more relaxed, on average. They are spared some of the burden of thinking about the future. As a result, they get more pleasure out of present, ordinary activities.

I’d rather think that elder happiness is an accomplishment, not a condition, that people get better at living through effort, by mastering specific skills. I’d like to think that people get steadily better at handling life’s challenges. In middle age, they are confronted by stressful challenges they can’t control, like having teenage children. But, in old age, they have more control over the challenges they will tackle and they get even better at addressing them.

Because America never had kings or lords, it sometimes seems less inclined to worry about signs that its elite is calcifying.

Thomas Jefferson drew a distinction between a natural aristocracy of the virtuous and talented, which was a blessing to a nation, and an artificial aristocracy founded on wealth and birth, which would slowly strangle it.

When the robber barons accumulated fortunes that made European princes envious, the combination of their own philanthropy, their children’s extravagance and federal trust-busting meant that Americans never discovered what it would be like to live in a country where the elite could reliably reproduce themselves.

One pill makes you smarter. One pill makes you thin. One pill makes you happy. Another keeps you energized. And so what if tests conducted by scientists in New York and Canada have found that the substances behind these miracle enhancements may contain nothing more than powdered rice or houseplants. If enough people believe they’ll be healthier, well, it’s a nice racket.

Nice, to the tune of $13 billion a year in sales. And here in Utah, which is to the dietary supplement business what Northern California is to marijuana, a huge industry has taken hold,

We’re not talking drugs, or even, in many cases, food here. Drugs have to undergo rigorous testing and review by the federal government. Dietary supplements do not. Drugs have to prove to be effective. Dietary supplements do not.

"The way we are interacting with the media might be affecting how we think, and this link seems to have a biological basis,” wrote lead researcher Kep Kee Loh of Singapore's Duke-NUS Graduate Medical School in an email to The Huffington Post.

While Loh’s study doesn’t establish whether media multitasking caused diminished brain matter, or if people with smaller ACCs are more prone to multitasking, Loh notes that previous studies have linked media multitasking to a diminished ability to control emotions and thoughts, and smaller ACC regions have also been linked to that same inability.

Loh plans to expand on the findings by conducting a longitudinal study on the relationship between multitasking and brain matter, which would evaluate the association over a longer period of time, but would still not establish cause. Meanwhile, study co-author Ryota Kanai is taking on a research project about how computer exposure might change brain structure.