Group items tagged

the popular suffix “maxxing” for “maximizing” (e.g., “I’m burritomaxxing” instead of “I’m eating a lot of burritos”) is drawn from the incel idea of “looksmaxxing,” or “maximizing attractiveness” through surgical or cosmetic techniques.

Then there’s the word “cucked” for “weakened” or “emasculated.” If the taqueria is out of burritos, you might be “tacocucked,” drawing on the incel idea of being sexually emasculated by more attractive “chads.

finally, we have the word “sigma” for “assertive male,” which comes from an incel’s desired position outside the social hierarchy.

there’s a dark side to the site as well — certain boards, like /r9k/, are known breeding grounds for incel discussion, and the source of the incel words being used today.

These slang terms developed on 4chan precisely because of the site’s anonymity. Since users don’t have identifiable aliases, they signal their in-group status through performative fluency in shared slang

Memes and niche vocabulary become a form of cultural currency, fueling their proliferation.

From there, those words filter out to more mainstream websites such as Reddit and eventually become popularized by viral memes and TikTok trends. Social media algorithms do the rest of the work by curating recommended content for viewers.

Because these terms often spread in ironic contexts, people find them funny, engage with them and are eventually rewarded with more memes featuring incel vocabulary.

Creators are not just aware of this process — they are directly incentivized to abet it. We know that using trending audio helps our videos perform better and that incorporating popular metadata with hashtags or captions will help us reach wider audiences

kids aren’t actually saying “cucked” because they’re “blackpilled”; they’re using it for the same reason all kids use slang: It helps them bond as a group. And what are they bonding over? A shared mockery of incel ideas.

These words capture an important piece of the Gen Z zeitgeist. We should therefore be aware of them, keeping in mind that they’re being used ironically.

People with heart failure-related difficulties could monitor blood flow and body temperature; those with central nervous system issues, including schizophrenia and Alzheimer’s disease, could take the pills to monitor vital signs in real time.

Future generations of these pills could even be convenience tools.

Once that pill is in your body, you could pick up your smartphone and not have to type in a password. Instead, you are the password. Sit in the car and it will start. Touch the handle to your home door and it will automatically unlock. “Essentially, your entire body becomes your authentication token,

“The wonderful is that there are a great number of things you want to know about yourself on a continual basis, especially if you’re diabetic or suffer from another disease. The terrible is that health insurance companies could know about the inner workings of your body.”

And the implications of a tiny computer inside your body being hacked? Let’s say they are troubling.

After it has done its job, flowing down around the stomach and through the intestinal tract, what happens next?“It passes naturally through the body in about 24 hours,” Ms. Carbonelli said, but since each pill costs $46, “some people choose to recover and recycle it.”

These are the Frankenstein remedies — botanicals, herbs, minerals, enzymes, amino acids, dried stuff. They’re “natural.” They’re not cheap. And Americans pop them like Skittles, despite recent studies showing that nearly a third of all herbal supplements on the market may be outright frauds.

We’re not talking drugs, or even, in many cases, food here. Drugs have to undergo rigorous testing and review by the federal government. Dietary supplements do not. Drugs have to prove to be effective. Dietary supplements do not.

Even though serious illnesses, and some deaths are on the rise from misuse of these supplements, Hatch is determined to keep regulators at bay. “I am committed to protect this industry and the integrity of its products,” he told a gathering of potency pill-pushers and the like in Utah last fall.

what about the medical implications? These pills and powders can’t, by law, make specific claims to cure anything. So they claim to make you healthier. The consumer is left playing doctor, reading questionable assertions that course through the unfiltered garbage of the Internet.

there was this finding reported in the authoritative Annals of Internal Medicine: “Enough is enough: Stop wasting money on vitamin and mineral supplements.”

So, the industry keeps growing, with 65,000 dietary supplements now on the market, consumed by nearly half of all Americans. The larger issue is mistrust of authority, a willful ignorance that knows no political side. Thus, right-wing libertarians promote a freewheeling market of quack products, while left-wing conspiracy theorists disdain modern medicine in favor of anything sold as “natural” or vaguely countercultural. These are some of the same people who will not vaccinate their children.

Often, preliminary studies fuel irrational exuberance about a promising dietary supplement, leading millions of people to buy in to the trend. Many never stop. They continue even though more rigorous studies — which can take many years to complete — almost never find that vitamins prevent disease, and in some cases cause harm

There’s no conclusive evidence that dietary supplements prevent chronic disease in the average American, Dr. Manson said. And while a handful of vitamin and mineral studies have had positive results, those findings haven’t been strong enough to recommend supplements to the general American public, she said.

The National Institutes of Health has spent more than $2.4 billion since 1999 studying vitamins and minerals. Yet for “all the research we’ve done, we don’t have much to show for it,” said Dr. Barnett Kramer, director of cancer prevention at the National Cancer Institute.

A big part of the problem, Dr. Kramer said, could be that much nutrition research has been based on faulty assumptions, including the notion that people need more vitamins and minerals than a typical diet provides; that megadoses are always safe; and that scientists can boil down the benefits of vegetables like broccoli into a daily pill.

when researchers tried to deliver the key ingredients of a healthy diet in a capsule, Dr. Kramer said, those efforts nearly always failed.

It’s possible that the chemicals in the fruits and vegetables on your plate work together in ways that scientists don’t fully understand — and which can’t be replicated in a table

More important, perhaps, is that most Americans get plenty of the essentials, anyway. Although the Western diet has a lot of problems — too much sodium, sugar, saturated fat and calories, in general — it’s not short on vitamins

Without even realizing it, someone who eats a typical lunch or breakfast “is essentially eating a multivitamin,”

The body naturally regulates the levels of many nutrients, such as vitamin C and many B vitamins, Dr. Kramer said, by excreting what it doesn’t need in urine. He added: “It’s hard to avoid getting the full range of vitamins.”

Not all experts agree. Dr. Walter Willett, a professor at the Harvard T.H. Chan School of Public Health, says it’s reasonable to take a daily multivitamin “for insurance.” Dr. Willett said that clinical trials underestimate supplements’ true benefits because they aren’t long enough, often lasting five to 10 years. It could take decades to notice a lower rate of cancer or heart disease in vitamin taker

For Charlsa Bentley, 67, keeping up with the latest nutrition research can be frustrating. She stopped taking calcium, for example, after studies found it doesn’t protect against bone fractures. Additional studies suggest that calcium supplements increase the risk of kidney stones and heart disease.

People who take vitamins tend to be healthier, wealthier and better educated than those who don’t, Dr. Kramer said. They are probably less likely to succumb to heart disease or cancer, whether they take supplements or not. That can skew research results, making vitamin pills seem more effective than they really are

Because folic acid can lower homocysteine levels, researchers once hoped that folic acid supplements would prevent heart attacks and strokes.In a series of clinical trials, folic acid pills lowered homocysteine levels but had no overall benefit for heart disease, Dr. Lichtenstein said

When studies of large populations showed that people who eat lots of seafood had fewer heart attacks, many assumed that the benefits came from the omega-3 fatty acids in fish oil, Dr. Lichtenstein said.Rigorous studies have failed to show that fish oil supplements prevent heart attacks

But it’s possible the benefits of sardines and salmon have nothing to do with fish oil, Dr. Lichtenstein said. People who have fish for dinner may be healthier as a result of what they don’t eat, such as meatloaf and cheeseburgers.

“Eating fish is probably a good thing, but we haven’t been able to show that taking fish oil [supplements] does anything for you,

In the tiny amounts provided by fruits and vegetables, beta carotene and similar substances appear to protect the body from a process called oxidation, which damages healthy cells, said Dr. Edgar Miller, a professor of medicine at Johns Hopkins School of Medicine.Experts were shocked when two large, well-designed studies in the 1990s found that beta carotene pills actually increased lung cancer rates.

Likewise, a clinical trial published in 2011 found that vitamin E, also an antioxidant, increased the risk of prostate cancer in men by 17 percent

“Vitamins are not inert,” said Dr. Eric Klein, a prostate cancer expert at the Cleveland Clinic who led the vitamin E study. “They are biologically active agents. We have to think of them in the same way as drugs. If you take too high a dose of them, they cause side effects.”

“We should be responsible physicians,” she said, “and wait for the data.”

many argued that we could never be justified in depriving someone of his free will, no matter how gruesome the violence that would thereby be prevented. No doubt any proposal to develop a morality pill would encounter the same objection.

If so, would people choose to take it? Could criminals be given the option, as an alternative to prison, of a drug-releasing implant that would make them less likely to harm others?

But if our brain’s chemistry does affect our moral behavior, the question of whether that balance is set in a natural way or by medical intervention will make no difference in how freely we act. If there are already biochemical differences between us that can be used to predict how ethically we will act, then either such differences are compatible with free will, or they are evidence that at least as far as some of our ethical actions are concerned, none of us have ever had free will anyway.

The ever increasing list of fat-burning supplements is industry driven, and is likely to grow at a rate that is not and cannot be matched by similar increase in scientific underpinning.

In other words, marketers are quick to announce miracle solutions based of the flimsiest of evidence collected on a few lab mice or a cell culture.

Health claims were introduced in 1994, have been so miserably abused and have become so utterly misleading that it’s just time to say goodbye.

it helped shift moral psychology away from rationalist models that dominated in the 1980s and 1990s. In its place Haidt offered an understanding of morality from an intuitive and automatic level. As Haidt says on his website, “we are just not very good at thinking open-mindedly about moral issues, so rationalist models end up being poor descriptions of actual moral psychology.”

“the mind is divided into parts that sometimes conflict. Like a rider on the back of an elephant, the conscious, reasoning part of the mind has only limited control of what the elephant does.”

In the last few decades psychology began to understand the unconscious mind not as dark and suppressed as Freud did, but as intuitive, highly intelligent and necessary for good conscious reasoning. “Elephants,” he reminded me, “are really smart, much smarter than horses.”

we are 90 percent chimp 10 percent bee. That is to say, though we are inherently selfish, human nature is also about being what he terms “groupish.” He explained to me like this:

they developed the idea that humans possess six universal moral modules, or moral “foundations,” that get built upon to varying degrees across culture and time. They are: Care/harm, Fairness/cheating, Loyalty/betrayal, Authority/subversion, Sanctity/degradation, and Liberty/oppression. Haidt describes these six modules like a “tongue with six taste receptors.” “In this analogy,” he explains in the book, “the moral matrix of a culture is something like its cuisine: it’s a cultural construction, influenced by accidents of environment and history, but it’s not so flexible that anything goes. You can’t have a cuisine based on grass and tree bark, or even one based primarily on bitter tastes. Cuisines vary, but they all must please tongues equipped with the same five taste receptors. Moral matrices vary, but they all must please righteous minds equipped with the same six social receptors.”

The questionnaire eventually manifested itself into the website www.YourMorals.org, and it has since gathered over two hundred thousand data points. Here is what they found:

This is the crux of the disagreement between liberals and conservatives. As the graph illustrates, liberals value Care and Fairness much more than the other three moral foundations whereas conservative endorse all five more or less equally. This shouldn’t sound too surprising, liberals tend to value universal rights and reject the idea of the United States being superior while conservatives tend to be less concerned about the latest United Nation declaration and more partial to the United States as a superior nation.

Haidt began reading political psychology. Karen Stenner’s The Authoritarian Dynamic, “conveyed some key insights about protecting the group that were particularly insightful,” he said. The work of the French sociologist Emile Durkheim was also vital. In contrast to John Stuart Mill, a Durkheimian society, as Haidt explains in an essay for edge.org, “would value self-control over self-expression, duty over rights, and loyalty to one’s groups over concerns for out-groups.”

He was motivated to write The Righteous Mind after Kerry lost the 2004 election: “I thought he did a terrible job of making moral appeals so I began thinking about how I could apply moral psychology to understand political divisions. I started studying the politics of culture and realized how liberals and conservatives lived in their own closed worlds.” Each of these worlds, as Haidt explains in the book, “provides a complete, unified, and emotionally compelling worldview, easily justified by observable evidence and nearly impregnable to attack by arguments from outsiders.” He describes them as “moral matrices,” and thinks that moral psychology can help him understand them.

“When I say that human nature is selfish, I mean that our minds contain a variety of mental mechanisms that make us adept at promoting our own interests, in competition with our peers. When I say that human nature is also groupish, I mean that our minds contain a variety of mental mechanisms that make us adept at promoting our group’s interests, in competition with other groups. We are not saints, but we are sometimes good team players.” This is what people who had studied morality had not realized, “that we evolved not just so I can treat you well or compete with you, but at the same time we can compete with them.”

At first, Haidt reminds us that we are all trapped in a moral matrix where

our “elephants” only look for what confirms its moral intuitions while our “riders” play the role of the lawyer; we team up with people who share similar matrices and become close-minded; and we forget that morality is diverse. But on the other hand, Haidt is offering us a choice: take the blue pill and remain happily delusional about your worldview, or take the red pill, and, as he said in his 2008 TED talk, “learn some moral psychology and step outside your moral matrix.”

The great Asian religions, Haidt reminded the crowd at TED, swallowed their pride and took the red pill millennia ago. And by stepping out of their moral matrices they realized that societies flourish when they value all of the moral foundations to some degree. This is why Ying and Yang aren’t enemies, “they are both necessary, like night and day, for the functioning of the world.” Or, similarly, why the two of the high Gods in Hinduism, Vishnu the preserver (who stands for conservative principles) and Shiva the destroyer (who stands for liberal principles) work together.

One huge problem with scientism is that it invites, as an almost allergic reaction, the total rejection of science. As we know to our cost, we witness this every day with climate change deniers, flat-earthers and religious fundamentalists

Frank’s point is that our society is deeply confused by the occasions when a blue pill is required and not required, or when we need a causal explanation and when we need a further description, clarification or elucidation. We tend to get muddled and imagine that one kind of explanation (usually the causal one) is appropriate in all occasions when it is not.

What is in play here is the classical distinction made by Max Weber between explanation and clarification, between causal or causal-sounding hypotheses and interpretation. Weber’s idea is that natural phenomena require causal explanation, of the kind given by physics, say, whereas social phenomena require elucidation — richer, more expressive descriptions.

In Frank’s view, one major task of philosophy is help us get clear on this distinction and to provide the right response at the right time. This, of course, requires judgment, which is no easy thing to teach.

Frank’s point, which is still hugely important, is that there is no theory of everything, nor should there be. There is a gap between nature and society. The mistake, for which scientism is the name, is the belief that this gap can or should be filled.

On a ferry you want a blue pill that is going to alleviate the symptoms of seasickness and make you feel better.

in order to confront the challenge of obscurantism, we do not simply need to run into the arms of scientism. What is needed is a clearer overview of the occasions when a scientific remark is appropriate and when we need something else, the kind of elucidation we find in stories, poetry or indeed when we watch a movie

People often wonder why there appears to be no progress in philosophy, unlike in natural science, and why it is that after some three millenniums of philosophical activity no dramatic changes seem to have been made to the questions philosophers ask. The reason is because people keep asking the same questions and perplexed by the same difficulties

Wittgenstein puts the point rather directly: “Philosophy hasn’t made any progress? If somebody scratches the spot where he has an itch, do we have to see some progress?”

Philosophy scratches at the various itches we have, not in order that we might find some cure for what ails us, but in order to scratch in the right place and begin to understand why we engage in such apparently irritating activity.

This is one way of approaching the question of life’s meaning. Human beings have been asking the same kinds of questions for millenniums and this is not an error. It testifies to the fact that human being are rightly perplexed by their lives. The mistake is to believe that there is an answer to the question of life’s meaning

The point, then, is not to seek an answer to the meaning of life, but to continue to ask the question.

We don’t need an answer to the question of life’s meaning, just as we don’t need a theory of everything. What we need are multifarious descriptions of many things, further descriptions of phenomena that change the aspect under which they are seen, that light them up and let us see them anew

No one should seek to die or give in to a disease they can legitimately fight. God knows how many pills I take a day to keep the virus – and all its and their side-effects at bay. But I get to live healthily and meaningfully. The way some elaborate and cutting edge treatments all but kill the patient in order to save her troubles me. It’s a loss of perspective as well as immensely expensive for the entire system.

our culture’s gradual alienation from the fact of our deaths – our distancing ourselves even from the old and infirm in ways previous cultures didn’t and couldn’t – is not, in my view a healthy thing.

these sophisticated treatments are taking healthcare money away from the young, taking up more and more of our collective healthcare resources, and extending lives only be perpetuating continuous agony and nausea and pain for the patient and devastating consequences for families and friends.

We will all die. We should not seek it. But we should not flee from it for ever.

at some point what seems to me to matter more is not the length of our lives but the content of them and the manner of our deaths.

At some point, medicine is a function of a social disease of modernity: the flight from our own mortality. But fleeing it does not defuse it. Only facing it does.

WebMD is a corporation that started as an ad-supported health-alarmism site with revenues of $504 million in 2010

the Mayo Clinic is a nonprofit medical-practice-and-research group that started as a clinic. Mayo’s storied past as the country’s premier research hospital, in Rochester, Minn., and its storied present as one of Fortune’s “100 Best Companies to Work For” surface in the integrity of the site itself, which — though not ad-free — is spare and neatly organized, with the measured, learned voice of the best doctors

The integrity of the whole institution is on the line with this site, and the Mayo Clinic has every motivation to keep its information authoritative and up to date.

“These are very difficult tradeoffs that our society has to make,” said Dr. Woodcock. “The reason we approve these drugs is for people in pain. But we can’t ignore the epidemic on the other side.”

In 2011, about 131 million prescriptions for hydrocodone-containing medications were written for some 47 million patients, according to government estimates. That volume of prescriptions amounts to about five billion pills.

Schedule II drugs are those drugs with the highest potential for abuse that can be legally prescribed.

Along with changing how doctors prescribe these drugs, the classification change will also impose added storage and recordkeeping requirements on druggists. In some states, nurse practitioners and other health care professionals who can currently prescribe hydrocodone-containing drugs may no longer be able to do so.

An examination of the Darwinian corpus shows that many of the most important changes centered on how he wished to present the role of “chance” in evolution to an ever-expanding reading public, especially after the Origin first appeared.

But I try to set out and move through with a clean slate, basing my claims on Darwin’s ipsissima verba rather than on what others have said.

The earth, its geological features, and its organic inhabitants are here only through lucky accidents? For many people that was a hard pill to swallow. Darwin did accept it, but also knew he would have to get his audience to accept it too if he were to succeed in establishing his theory as the correct account of the origin of species.

“I do have another question,” I said. “Stool softeners — certainly, you prescribe those? That’s pretty standard with anesthesia throughout the modern world, I believe.”

“You won’t need those,” he answered in his calm voice. “Your body will function just fine. Just give it a day or two. Drink a cup of coffee, slowly

“Pain is a part of life. We cannot eliminate it nor do we want to. The pain will guide you. You will know when to rest more; you will know when you are healing.

If I give you Vicodin, you will no longer feel the pain, yes, but you will no longer know what your body is telling you. You might overexert yourself because you are no longer feeling the pain signals. All you need is rest.

And please be careful with ibuprofen. It’s not good for your kidneys. Only take it if you must. Your body will heal itself with rest.

I didn’t mention that I use ibuprofen like candy. Why else do they come in such jumbo sizes at American warehouse stores?

introduces thought and balance to people’s lives.

Thomas S. Kuhn

. In 2009, the researchers reported in the Journal of the American Medical Association that taking high doses of vitamin B12 along with folic acid (technically vitamin B9) was associated with greater risk of cancer and all-cause mortality.

Lung-cancer risk among men who took 20 milligrams of B6 daily for years was twice that of men who didn’t. Among people who smoke, the effect appeared to be synergistic, with B6 usage increasing risk threefold. The risk was even worse among smokers taking B12. Using more than 55 micrograms daily appeared to almost quadruple lung-cancer risk.

The research team is quick to note that the doses of B vitamins in question are enormous. The U.S. Recommended Dietary Allowance for B6 is 1.7 milligrams per day, and for B12 it’s 2.4 micrograms. The high-risk group in the study was taking around 20 times these amounts.That could seem nonsensical, except that these are the doses for sale at healthy-seeming places like Whole Foods and GNC. Many sellers offer daily 100-milligram B6 pills. B12 is available in doses of 5,000 micrograms.

There are legitimate and important uses for B-vitamin supplements, but the emerging evidence suggests we’re best to treat them more like pharmaceuticals than like panaceas to be shoveled into us in pursuit of energy, metabolic fortitude, “cardioprotection,” “bone wellness,” or whatever way in which we’d like to be better.

The current law gives consumers no reason to expect that risks will be listed on the labels of these products, or that health claims are accurate. A product like a high-dose B6 and B12 supplement hits shelves, and only decades later do researchers begin to understand the long-term health effects, who might benefit from taking it, and who might be harmed.  

“My definition of addiction is a repetitive behavior that some people find difficult to quit,”

Mr. Szymanczyk was speaking in the context of smoking. But a fascinating new book by Michael Moss, an investigative journalist and best-selling author, argues that the tobacco executive’s definition of addiction could apply to our relationship with another group of products that Philip Morris sold and manufactured for decades: highly processed foods.

In his new book, “Hooked,” Mr. Moss explores the science behind addiction and builds a case that food companies have painstakingly engineered processed foods to hijack the reward circuitry in our brains, causing us to overeat and helping to fuel a global epidemic of obesity and chronic disease.

Mr. Moss suggests that processed foods like cheeseburgers, potato chips and ice cream are not only addictive, but that they can be even more addictive than alcohol, tobacco and drugs.

In another cynical move, Mr. Moss writes, food companies beginning in the late 1970s started buying a slew of popular diet companies, allowing them to profit off our attempts to lose the weight we gained from eating their products.

Heinz, the processed food giant, bought Weight Watchers in 1978 for $72 million. Unilever, which sells Klondike bars and Ben & Jerry’s ice cream, paid $2.3 billion for SlimFast in 2000. Nestle, which makes chocolate bars and Hot Pockets, purchased Jenny Craig in 2006 for $600 million. And in 2010 the private equity firm that owns Cinnabon and Carvel ice cream purchased Atkins Nutritionals, the company that sells low-carb bars, shakes and snacks. Most of these diet brands were later sold to other parent companies.

“The food industry blocked us in the courts from filing lawsuits claiming addiction; they started controlling the science in problematic ways, and they took control of the diet industry,”

“I’ve been crawling through the underbelly of the processed food industry for 10 years and I continue to be stunned by the depths of the deviousness of their strategy to not just tap into our basic instincts, but to exploit our attempts to gain control of our habits.”

The book explained how companies formulate junk foods to achieve a “bliss point” that makes them irresistible and market those products using tactics borrowed from the tobacco industry.

In the 1980s, Philip Morris acquired Kraft and General Foods, making it the largest manufacturer of processed foods in the country, with products like Kool-Aid, Cocoa Pebbles, Capri Sun and Oreo cookies.

“I had tried to avoid the word addiction when I was writing ‘Salt Sugar Fat,’” he said. “I thought it was totally ludicrous. How anyone could compare Twinkies to crack cocaine was beyond me.”

Witness

But as he dug into the science that shows how processed foods affect the brain, he was swayed

One crucial element that influences the addictive nature of a substance and whether or not we consume it compulsively is how quickly it excites the brain.

The faster it hits our reward circuitry, the stronger its impact.

That is why smoking crack cocaine is more powerful than ingesting cocaine through the nose, and smoking cigarettes produces greater feelings of reward than wearing a nicotine patch

: Smoking reduces the time it takes for drugs to hit the brain.

But no addictive drug can fire up the reward circuitry in our brains as rapidly as our favorite foods, Mr. Moss writes. “The smoke from cigarettes takes 10 seconds to stir the brain, but a touch of sugar on the tongue will do so in a little more than a half second, or six hundred milliseconds, to be precise,

This puts the term “fast food” in a new light. “Measured in milliseconds, and the power to addict, nothing is faster than processed food in rousing the brain,” he added.

Mr. Moss explains that even people in the tobacco industry took note of the powerful lure of processed foods.

In “Hooked,” Michael Moss explores how no addictive drug can fire up the reward circuitry in our brains as rapidly as our favorite foods.

As litigation against tobacco companies gained ground in the 1990s, one of the industry’s defenses was that cigarettes were no more addictive than Twinkies.

It may have been on to something.

“Smoking was given an 8.5, nearly on par with heroin,” Mr. Moss writes. “But overeating, at 7.3, was not far behind, scoring higher than beer, tranquilizers and sleeping pills.

But processed foods are not tobacco, and many people, including some experts, dismiss the notion that they are addictive. Mr. Moss suggests that this reluctance is in part a result of misconceptions about what addiction entails.

For one, a substance does not have to hook everyone for it to be addictive.

Studies show that most people who drink or use cocaine do not become dependent

Nor does everyone who smokes or uses painkillers become addicted.

Mr. Moss said that people who struggle with processed food can try simple strategies to conquer routine cravings, like going for a walk, calling a friend or snacking on healthy alternatives like a handful of nuts. But for some people, more extreme measures may be necessary.

“It depends where you are on the spectrum,” he said. “I know people who can’t touch a grain of sugar without losing control. They would drive to the supermarket and by the time they got home their car would be littered with empty wrappers. For them, complete abstention is the solution.”

But that blessed feeling evaporated in June of 2019, when I lost my daughter, Frankie, to suicide, three weeks before her high school graduation

Ever since that day, I have thought of little else except how I could help the next struggling teenager, the next Frankie.

Several days after her passing, we opened our home up to our community, including Frankie’s very large group of teenage friends

“What strength Frankie had. It must have taken enormous energy for her to do what she did each day.”

That was Frankie. She had the strength to engage in school and in theater, despite her anxiety and depression. She had an ability to connect — emotionally, profoundly — with others, even when she was struggling herself

“empathy personified, with quite the fabulous earring collection.”

Whether that strength came from her home or somewhere else, or both, Frankie just had a way of drawing out warmth wherever she went.

Just as my parents couldn’t predict in the 1980s what seatbelt safety would look like now, I am not sure what suicide prevention should look like in the future.

Suicidal thinking, whether it is the result of mental illness, stress, trauma or loss, is actually far more common and difficult to see than many of us realize

A June 2020 Centers for Disease Control survey found that one in four 18- to 24-year-olds reported that they had seriously thought about taking their lives in the past 30 days; prepandemic estimates found that just under one in five high schoolers had seriously considered suicide, and just under one in 10 had made at least one suicide attempt during the previous year.

Despite 50 years of research, predicting death by suicide is still nearly impossible

Like others who have lost a child to suicide, I have spent countless hours going over relentless “what ifs.”

Maybe what we need are seatbelts for suicide.

“Click it or Ticket” was born in part out of a concern in the 1980s about teenagers dying in car accidents. Just as with suicides today, adults couldn’t predict who would get into a car accident, and one of the best solutions we had — seatbelts — was used routinely, in some estimates, by only 15 percent of the population. Indeed, as children, my siblings and I used to make a game of rolling around in the back of our car, seatbelts ignored.

Three decades later, our world is unlike anything I could have imagined as a child. Putting on a seatbelt is the first lesson of driver’s education; cars get inspected annually for working seatbelts; car companies embed those annoying beeping sounds to remind you to buckle your seatbelt

But like many who struggle with suicidal thinking, she kept her own pain camouflaged for a long time, perhaps for too long.

Most of us (estimates range as high as 91 percent) now wear a seatbelt.

But I imagine a world in which every health worker, school professional, employer and religious leader can recognize the signs of suicidal thinking and know how to ask about it, respond to it and offer resources to someone who is struggling

When I told Frankie’s orthodontist about her suicide, his response surprised me: “We really don’t come across that in our practice.” Even though orthodontists don’t ask about it, they see children during their early teenage years, when suicidal thinking often begins to emerge. Can you imagine a world in which signs for the prevention hotline and text line are posted for kids to see as they get their braces adjusted?

What if the annual teenage pediatric checkup involved a discussion of one-at-a-time pill packaging and boxes to lock up lethal medications, the way there is a discussion of baby-proofing homes when children start to crawl? What if pediatricians handed each adolescent a card with the prevention hotline on it (or better yet, if companies preprogrammed that number into cellphones) and the pediatrician talked through what happens when a teenager calls? What if doctors coached parents on how to ask their teenager, “Are you thinking about suicide?”

What if we required and funded every school to put in place one of the existing programs that train teachers and other school professionals to be a resource for struggling students?

I recognize that despite progress identifying effective programs to combat suicidal thinking, their success rate and simplicity does not compare with what we see with seatbelts. But that doesn’t mean we shouldn’t do more.

Part of doing more also includes making the world more just and caring. To give one example, state-level same-sex-marriage policies that were in place before the Supreme Court legalized same-sex marriage nationally have been linked to reductions in suicide attempts among adolescents, especially among sexual minorities.

Just as safer highways and car models make seatbelts more effective, asking about and responding to suicidal thinking is only one part of a solution that also includes attention to societal injustices.

I understand, of course, that asking about suicidal thinking is scary. But if it is scary for you to ask about it, it is even scarier for the teenager who is thinking about it.

I will never forget sitting with Frankie in the waiting room in the pediatric psychiatric wing on the night I brought her to the inpatient unit, three months before she took her life

“You know, I am so glad you finally know.” I could hear the relief in her voice. I just nodded, understandingly, but it broke my heart that she held on to such a painful secret for so long.

I find myself inspired by Frankie’s teenage friends, who cared deeply for her and now support one another after her passing.

On good days, she would sit on the worn couch in that office, snuggle in a pile of teenagers and discuss plays, schoolwork and their lives.

And in that corner space, she would text a friend to help her get to class or, after she had opened up about her struggles, encourage others to open up as well.

The fall after Frankie left us, some students decided to remake that hidden corner, dotting the walls with colored Post-it notes. Scrawled on a pink Post-it were the words “you matter”; a yellow one read “it gets better”; an orange one shared a cellphone number to call for help. Tiny Post-it squares had transformed the corner into a space to comfort, heal and support the next struggling teenager.

I don’t know if a seatbelt approach would have saved Frankie. And I understand that all the details of such an approach aren’t fully worked out here. But I don’t want us to lose any more children because we weren’t brave enough to take on something that scares us, something we don’t fully understand, something that is much more prevalent than many of us realize.

If 17- and 18-year-olds who’ve lost a friend have the strength to imagine a world dotted with healing, then the least we can do as adults is design and build the structure to support them

The treatment helped 13.4% of patients with their addiction, compared with 2.5% of the placebo group.

This medication therapy provides another tool for doctors to try with patients.

"As we understand the complexity of the human brain, it becomes very much of a magical thinking that one pill will solve the problem of addiction,"

The treatment regimen in the trial combined two medications that have been studied separately for treating methamphetamine addiction with limited success.

This clinical trial was successful enough that the National Institute on Drug Addiction's Volkow says she expects to move forward toward securing FDA approval.

lack of medical treatments for those addicted to meth has complicated efforts to curb demand for the drug.

The human cost has been catastrophic. Researchers say overdose deaths linked to meth increased fourfold over the last decade.

Even users who don't overdose often experience damage to the heart and other tissues, and can see their lives spiral out of control.

"For heroin users, there's methadone, there's suboxone. I just wonder why we haven't researched [treatments for] this drug yet,"

"It's about evidence-based care, it's about empathy and it's about survivability,"

"There are times when I want to hug him and hold him and comfort him and there are times when I want to punch him in the face," said Mr Brafman.

The medication is used to treat Aids patients, the pregnant and elderly. Price gouging is not illegal or even unusual in the US pharmaceutical industry.

Before his sentencing, Mr Brafman told the judge that Shkreli is a "somewhat broken" person who suffered from depression and an anxiety disorder.

But a month later he offered social media followers $5,000 if they could bring him hair from former US presidential candidate Hillary Clinton, who repeatedly criticised him during her campaign.