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Emily Horwitz

Mammoth fragments from Siberia raise cloning hopes - Yahoo! News - 1 views

  • Scientists have discovered well-preserved frozen woolly mammoth fragments deep in Siberia that may contain living cells, edging a tad closer to the "Jurassic Park" possibility of cloning a prehistoric animal, the mission's organizer said Tuesday.
  • Expedition chief Semyon Grigoryev said Korean scientists with the team had set a goal of finding living cells in the hope of cloning a mammoth. Scientists have previously found bones and fragments but not living cells.
  • Some believe it's possible to recreate the prehistoric animal if they find living cells in the permafrost.
Javier E

Opinion | Cloning Scientist Hwang Woo-suk Gets a Second Chance. Should He? - The New Yo... - 0 views

  • The Hwang Woo-suk saga is illustrative of the serious deficiencies in the self-regulation of science. His fraud was uncovered because of brave Korean television reporters. Even those efforts might not have been enough, had Dr. Hwang’s team not been so sloppy in its fraud. The team’s papers included fabricated data and pairs of images that on close comparison clearly indicated duplicity.
  • Yet as a cautionary tale about the price of fraud, it is, unfortunately, a mixed bag. He lost his academic standing, and he was convicted of bioethical violations and embezzlement, but he never ended up serving jail time
  • Although his efforts at cloning human embryos, ended in failure and fraud, they provided him the opportunities and resources he needed to take on projects, such as dog cloning, that were beyond the reach of other labs. The fame he earned in academia proved an asset in a business world where there’s no such thing as bad press.
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  • it is comforting to think that scientific truth inevitably emerges and scientific frauds will be caught and punished.
  • Dr. Hwang’s scandal suggests something different. Researchers don’t always have the resources or motivation to replicate others’ experiments
  • Even if they try to replicate and fail, it is the institution where the scientist works that has the right and responsibility to investigate possible fraud. Research institutes and universities, facing the prospect of an embarrassing scandal, might not do so.
Javier E

CarynAI, created with GPT-4 technology, will be your girlfriend - The Washington Post - 0 views

  • CarynAI also shows how AI applications can increase the ability of a single person to reach an audience of thousands in a way that, for users, may feel distinctly personal.
  • The impact could be enormous for someone forming something resembling a personal relationship with thousands or millions of online followers. It could also show how thin and tenuous these simulations of human connection could become.
  • CarynAI also is a reminder that sex and romance are often the first realm in which technological progress becomes profitable. Marjorie acknowledges that some of the exchanges with CarynAI become sexually explicit
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  • CarynAI is the first major release from a company called Forever Voices. The company previously has created realistic AI chatbots that allow users to talk with replicated versions of Steve Jobs, Kanye West, Donald Trump and Taylor Swift
  • CarynAI is a far more sophisticated product, the company says, and part of Forever Voices’ new AI companion initiative, meant to provide users with a girlfriend-like experience that fans can emotionally bond with.
  • John Meyer, CEO and founder of Forever Voices, said that he created the company last year, after trying to use AI to develop ways to reconnect with his late father, who passed away in 2017. He built an AI voice chatbot that replicated his late father’s voice and personality to talk to and found the experience incredibly healing. “It was a remarkable experience to talk to him again in a super realistic way,” Meyer said. “I’ve been in tech my whole life, I’m a programmer, so it was easy for me to start building something like that especially as things got more advanced with the AI space.”
  • Meyer’s company has about 10 employees. One job Meyer is hoping to fill soon is chief ethics officer. “There are a lot of ways to do this wrong,”
  • One safeguard is trying to limit the amount of time a user is allowed to chat with CarynAI. To keep users from becoming addicted, CarynAI is programmed to wind down conversations after about an hour, encouraging users to pick back up later. But there is no hard time limit on use, and some users are spending hours speaking to CarynAI per day, according to Marjorie’s manager, Ishan Goel.
  • “I consider myself a futurist at heart and when I look into the future I believe this is the beginning of a very diverse future consisting of AI to human companionship,”
  • Elizabeth Snower, founder of ICONIQ, which creates conversational 3D avatars, predicts that soon there will be “AI influencers on every social platform that are influencing consumer decisions.”
  • “A lot of people have just been kind of really mad at the existence of this. They think that it’s the end of humanity,” she said.
  • Marjorie hopes the backlash will fade when other online personalities begin rolling out their own AI companions
  • “I think in the next five years, most Americans will have an AI companion in their pocket in some way, shape or form, whether it’s an ultra flirty AI that you’re dating, an AI that’s your personal trainer, or simply a tutor companion. Those are all things that we are building internally,
  • That strikes AI adviser and investor Allie K. Miller as a likely outcome. “I can imagine a future in which everyone — celebrities, TV characters, influencers, your brother — has an online avatar that they invite their audience or friends to engage with. … With the accessibility of these models, I’m not surprised it’s expanding to scaled interpersonal relationships.”
Javier E

Is Anything Still True? On the Internet, No One Knows Anymore - WSJ - 1 views

  • Creating and disseminating convincing propaganda used to require the resources of a state. Now all it takes is a smartphone.
  • Generative artificial intelligence is now capable of creating fake pictures, clones of our voices, and even videos depicting and distorting world events. The result: From our personal circles to the political circuses, everyone must now question whether what they see and hear is true.
  • exposure to AI-generated fakes can make us question the authenticity of everything we see. Real images and real recordings can be dismissed as fake. 
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  • “When you show people deepfakes and generative AI, a lot of times they come out of the experiment saying, ‘I just don’t trust anything anymore,’” says David Rand, a professor at MIT Sloan who studies the creation, spread and impact of misinformation.
  • This problem, which has grown more acute in the age of generative AI, is known as the “liar’s dividend,
  • The combination of easily-generated fake content and the suspicion that anything might be fake allows people to choose what they want to believe, adds DiResta, leading to what she calls “bespoke realities.”
  • Examples of misleading content created by generative AI are not hard to come by, especially on social media
  • The signs that an image is AI-generated are easy to miss for a user simply scrolling past, who has an instant to decide whether to like or boost a post on social media. And as generative AI continues to improve, it’s likely that such signs will be harder to spot in the future.
  • “What our work suggests is that most regular people do not want to share false things—the problem is they are not paying attention,”
  • in the course of a lawsuit over the death of a man using Tesla’s “full self-driving” system, Elon Musk’s lawyers responded to video evidence of Musk making claims about this software by suggesting that the proliferation of “deepfakes” of Musk was grounds to dismiss such evidence. They advanced that argument even though the clip of Musk was verifiably real
  • are now using its existence as a pretext to dismiss accurate information
  • People’s attention is already limited, and the way social media works—encouraging us to gorge on content, while quickly deciding whether or not to share it—leaves us precious little capacity to determine whether or not something is true
  • If the crisis of authenticity were limited to social media, we might be able to take solace in communication with those closest to us. But even those interactions are now potentially rife with AI-generated fakes.
  • what sounds like a call from a grandchild requesting bail money may be scammers who have scraped recordings of the grandchild’s voice from social media to dupe a grandparent into sending money.
  • companies like Alphabet, the parent company of Google, are trying to spin the altering of personal images as a good thing. 
  • With its latest Pixel phone, the company unveiled a suite of new and upgraded tools that can automatically replace a person’s face in one image with their face from another, or quickly remove someone from a photo entirely.
  • Joseph Stalin, who was fond of erasing people he didn’t like from official photos, would have loved this technology.
  • In Google’s defense, it is adding a record of whether an image was altered to data attached to it. But such metadata is only accessible in the original photo and some copies, and is easy enough to strip out.
  • The rapid adoption of many different AI tools means that we are now forced to question everything that we are exposed to in any medium, from our immediate communities to the geopolitical, said Hany Farid, a professor at the University of California, Berkeley who
  • To put our current moment in historical context, he notes that the PC revolution made it easy to store and replicate information, the internet made it easy to publish it, the mobile revolution made it easier than ever to access and spread, and the rise of AI has made creating misinformation a cinch. And each revolution arrived faster than the one before it.
  • Not everyone agrees that arming the public with easy access to AI will exacerbate our current difficulties with misinformation. The primary argument of such experts is that there is already vastly more misinformation on the internet than a person can consume, so throwing more into the mix won’t make things worse.
  • it’s not exactly reassuring, especially given that trust in institutions is already at one of the lowest points in the past 70 years, according to the nonpartisan Pew Research Center, and polarization—a measure of how much we distrust one another—is at a high point.
  • “What happens when we have eroded trust in media, government, and experts?” says Farid. “If you don’t trust me and I don’t trust you, how do we respond to pandemics, or climate change, or have fair and open elections? This is how authoritarianism arises—when you erode trust in institutions.”
Ellie McGinnis

The Mammoth Cometh - NYTimes.com - 2 views

  • Brand helped to establish in 1996 to support projects designed to inspire “long-term responsibility.”
  • The theme of the talk was “Is Mass Extinction of Life on Earth Inevitable?”
  • the resurrection of extinct species, like the woolly mammoth, aided by new genomic technologies developed by the Harvard molecular biologist George Church.
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  • Just as the loss of a species decreases the richness of an ecosystem, the addition of new animals could achieve the opposite effect.
  • National Geographic Society hosted a larger conference to debate the scientific and ethical questions raised by the prospect of “de-extinction.
  • “De-extinction went from concept to potential reality right before our eyes,
  • less scientific, if more persuasive, argument was advanced by the ethicist Hank Greely and the law professor Jacob Sherkow, both of Stanford. De-extinction should be pursued, they argued in a paper published in Science, because it would be really
  • “This may be the biggest attraction and possibly the biggest benefit of de-extinction. It would surely be very cool to see a living woolly mammoth.”
  • They will replace chunks of band-tailed-pigeon DNA with synthesized chunks of passenger-pigeon DNA, until the cell’s genome matches their working passenger-pigeon genome.
  • Scientists predict that changes made by human beings to the composition of the atmosphere could kill off a quarter of the planet’s mammal species, a fifth of its reptiles and a sixth of its birds by 2050
  • This cloning method, called somatic cell nuclear transfer, can be used only on species for which we have cellular material.
  • There is a shortcut. The genome of a closely related species will have a high proportion of identical DNA, so it can serve as a blueprint, or “scaffold.”
  • By comparing the fragments of passenger-pigeon DNA with the genomes of similar species, researchers can assemble an approximation of an actual passenger-pigeon genome.
  • As with any translation, there may be errors of grammar, clumsy phrases and perhaps a few missing passages, but the book will be legible. It should, at least, tell a good story.
  • the genome will have to be inscribed into a living cell.
  • “We’ve framed it in terms of conservation,”
  • MAGE (Multiplex Automated Genome Engineering). MAGE is nicknamed the “evolution machine” because it can introduce the equivalent of millions of years of genetic mutations within minutes
  • Developmental and behavioral biologists would take over, just in time to answer some difficult questions. Chicks imitate their parents’ behavior. How do you raise a passenger pigeon without parents of its own species? And how do you train band-tailed pigeons to nurture the strange spawn that emerge from their eggs; chicks that, to them, might seem monstrous: an avian Rosemary’s Baby?
  • For endangered species with tiny populations, scientists would introduce genetic diversity to offset inbreeding.
  • They will try to alter the birds’ diets, migration habits and environment. The behavior of each subsequent generation will more closely resemble that of their genetic cousins.
  • For species threatened by contagion, an effort would be made to fortify their DNA with genes that make them disease-resistant
  • The scientific term for this type of genetic intervention is “facilitated adaptation.”
  • This optimistic, soft-focus fantasy of de-extinction, while thrilling to Ben Novak, is disturbing to many conservation biologists, who consider it a threat to their entire discipline and even to the environmental movement.
  • The first question posed by conservationists addresses the logic of bringing back an animal whose native habitat has disappeared. Why go through all the trouble just to have the animal go extinct all over again?
  • There is also anxiety about disease
  • “If you recreate a species genetically and release it, and that genotype is based on a bird from a 100-year-old environment, you probably will increase risk.”
  • “There’s always this fear that somehow, if we do it, we’re going to accidentally make something horrible, because only nature can really do it right. But nature is totally random. Nature makes monsters. Nature makes threats. Many of the things that are most threatening to us are a product of nature. Revive & Restore is not going to tip the balance in any way.”
  • De-extinction also poses a rhetorical threat to conservation biologists. The specter of extinction has been the conservation movement’s most powerful argument. What if extinction begins to be seen as a temporary inconvenience?
  • De-extinction suggests that we can technofix our way out of environmental issues generally, and that’s very, very bad.
  • How will we decide which species to resurrect?
  • Philip Seddon recently published a 10-point checklist to determine the suitability of any species for revival, taking into account causes of its extinction, possible threats it might face upon resurrection and man’s ability to destroy the species “in the event of unacceptable ecological or socioeconomic impacts.”
  • But the most visceral argument against de-extinction is animal cruelty.
  • “Is it fair to do this to these animals?” Shapiro asked. “Is ‘because we feel guilty’ a good-enough reason?” Stewart Brand made a utilitarian counterargument: “We’re going to go through some suffering, because you try a lot of times, and you get ones that don’t take. On the other hand, if you can bring bucardos back, then how many would get to live that would not have gotten to live?”
  • In “How to Permit Your Mammoth,” published in The Stanford Environmental Law Journal, Norman F. Carlin asks whether revived species should be protected by the Endangered Species Act or regulated as a genetically modified organism.
  • He concludes that revived species, “as products of human ingenuity,” should be eligible for patenting.
  • The term “de-extinction” is misleading. Passenger pigeons will not rise from the grave
  • Our understanding of the passenger pigeon’s behavior derives entirely from historical accounts.
  • There is no authoritative definition of “species.” The most widely accepted definition describes a group of organisms that can procreate with one another and produce fertile offspring, but there are many exceptions.
  • Theseus’ ship, therefore, “became a standing example among the philosophers . . . one side holding that the ship remained the same, and the other contending that it was not the same.”
  • What is coming will go well beyond the resurrection of extinct species. For millenniums, we have customized our environment, our vegetables and our animals, through breeding, fertilization and pollination. Synthetic biology offers far more sophisticated tools. The creation of novel organisms, like new animals, plants and bacteria, will transform human medicine, agriculture, energy production and much else.
Javier E

Accelerationism: how a fringe philosophy predicted the future we live in | World news |... - 1 views

  • Roger Zelazny, published his third novel. In many ways, Lord of Light was of its time, shaggy with imported Hindu mythology and cosmic dialogue. Yet there were also glints of something more forward-looking and political.
  • accelerationism has gradually solidified from a fictional device into an actual intellectual movement: a new way of thinking about the contemporary world and its potential.
  • Accelerationists argue that technology, particularly computer technology, and capitalism, particularly the most aggressive, global variety, should be massively sped up and intensified – either because this is the best way forward for humanity, or because there is no alternative.
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  • Accelerationists favour automation. They favour the further merging of the digital and the human. They often favour the deregulation of business, and drastically scaled-back government. They believe that people should stop deluding themselves that economic and technological progress can be controlled.
  • Accelerationism, therefore, goes against conservatism, traditional socialism, social democracy, environmentalism, protectionism, populism, nationalism, localism and all the other ideologies that have sought to moderate or reverse the already hugely disruptive, seemingly runaway pace of change in the modern world
  • Robin Mackay and Armen Avanessian in their introduction to #Accelerate: The Accelerationist Reader, a sometimes baffling, sometimes exhilarating book, published in 2014, which remains the only proper guide to the movement in existence.
  • “We all live in an operating system set up by the accelerating triad of war, capitalism and emergent AI,” says Steve Goodman, a British accelerationist
  • A century ago, the writers and artists of the Italian futurist movement fell in love with the machines of the industrial era and their apparent ability to invigorate society. Many futurists followed this fascination into war-mongering and fascism.
  • One of the central figures of accelerationism is the British philosopher Nick Land, who taught at Warwick University in the 1990s
  • Land has published prolifically on the internet, not always under his own name, about the supposed obsolescence of western democracy; he has also written approvingly about “human biodiversity” and “capitalistic human sorting” – the pseudoscientific idea, currently popular on the far right, that different races “naturally” fare differently in the modern world; and about the supposedly inevitable “disintegration of the human species” when artificial intelligence improves sufficiently.
  • In our politically febrile times, the impatient, intemperate, possibly revolutionary ideas of accelerationism feel relevant, or at least intriguing, as never before. Noys says: “Accelerationists always seem to have an answer. If capitalism is going fast, they say it needs to go faster. If capitalism hits a bump in the road, and slows down” – as it has since the 2008 financial crisis – “they say it needs to be kickstarted.”
  • On alt-right blogs, Land in particular has become a name to conjure with. Commenters have excitedly noted the connections between some of his ideas and the thinking of both the libertarian Silicon Valley billionaire Peter Thiel and Trump’s iconoclastic strategist Steve Bannon.
  • “In Silicon Valley,” says Fred Turner, a leading historian of America’s digital industries, “accelerationism is part of a whole movement which is saying, we don’t need [conventional] politics any more, we can get rid of ‘left’ and ‘right’, if we just get technology right. Accelerationism also fits with how electronic devices are marketed – the promise that, finally, they will help us leave the material world, all the mess of the physical, far behind.”
  • In 1972, the philosopher Gilles Deleuze and the psychoanalyst Félix Guattari published Anti-Oedipus. It was a restless, sprawling, appealingly ambiguous book, which suggested that, rather than simply oppose capitalism, the left should acknowledge its ability to liberate as well as oppress people, and should seek to strengthen these anarchic tendencies, “to go still further … in the movement of the market … to ‘accelerate the process’”.
  • By the early 90s Land had distilled his reading, which included Deleuze and Guattari and Lyotard, into a set of ideas and a writing style that, to his students at least, were visionary and thrillingly dangerous. Land wrote in 1992 that capitalism had never been properly unleashed, but instead had always been held back by politics, “the last great sentimental indulgence of mankind”. He dismissed Europe as a sclerotic, increasingly marginal place, “the racial trash-can of Asia”. And he saw civilisation everywhere accelerating towards an apocalypse: “Disorder must increase... Any [human] organisation is ... a mere ... detour in the inexorable death-flow.”
  • With the internet becoming part of everyday life for the first time, and capitalism seemingly triumphant after the collapse of communism in 1989, a belief that the future would be almost entirely shaped by computers and globalisation – the accelerated “movement of the market” that Deleuze and Guattari had called for two decades earlier – spread across British and American academia and politics during the 90s. The Warwick accelerationists were in the vanguard.
  • In the US, confident, rainbow-coloured magazines such as Wired promoted what became known as “the Californian ideology”: the optimistic claim that human potential would be unlocked everywhere by digital technology. In Britain, this optimism influenced New Labour
  • The Warwick accelerationists saw themselves as participants, not traditional academic observers
  • The CCRU gang formed reading groups and set up conferences and journals. They squeezed into the narrow CCRU room in the philosophy department and gave each other impromptu seminars.
  • The main result of the CCRU’s frantic, promiscuous research was a conveyor belt of cryptic articles, crammed with invented terms, sometimes speculative to the point of being fiction.
  • At Warwick, however, the prophecies were darker. “One of our motives,” says Plant, “was precisely to undermine the cheery utopianism of the 90s, much of which seemed very conservative” – an old-fashioned male desire for salvation through gadgets, in her view.
  • K-punk was written by Mark Fisher, formerly of the CCRU. The blog retained some Warwick traits, such as quoting reverently from Deleuze and Guattari, but it gradually shed the CCRU’s aggressive rhetoric and pro-capitalist politics for a more forgiving, more left-leaning take on modernity. Fisher increasingly felt that capitalism was a disappointment to accelerationists, with its cautious, entrenched corporations and endless cycles of essentially the same products. But he was also impatient with the left, which he thought was ignoring new technology
  • lex Williams, co-wrote a Manifesto for an Accelerationist Politics. “Capitalism has begun to constrain the productive forces of technology,” they wrote. “[Our version of] accelerationism is the basic belief that these capacities can and should be let loose … repurposed towards common ends … towards an alternative modernity.”
  • What that “alternative modernity” might be was barely, but seductively, sketched out, with fleeting references to reduced working hours, to technology being used to reduce social conflict rather than exacerbate it, and to humanity moving “beyond the limitations of the earth and our own immediate bodily forms”. On politics and philosophy blogs from Britain to the US and Italy, the notion spread that Srnicek and Williams had founded a new political philosophy: “left accelerationism”.
  • Two years later, in 2015, they expanded the manifesto into a slightly more concrete book, Inventing the Future. It argued for an economy based as far as possible on automation, with the jobs, working hours and wages lost replaced by a universal basic income. The book attracted more attention than a speculative leftwing work had for years, with interest and praise from intellectually curious leftists
  • Even the thinking of the arch-accelerationist Nick Land, who is 55 now, may be slowing down. Since 2013, he has become a guru for the US-based far-right movement neoreaction, or NRx as it often calls itself. Neoreactionaries believe in the replacement of modern nation-states, democracy and government bureaucracies by authoritarian city states, which on neoreaction blogs sound as much like idealised medieval kingdoms as they do modern enclaves such as Singapore.
  • Land argues now that neoreaction, like Trump and Brexit, is something that accelerationists should support, in order to hasten the end of the status quo.
  • In 1970, the American writer Alvin Toffler, an exponent of accelerationism’s more playful intellectual cousin, futurology, published Future Shock, a book about the possibilities and dangers of new technology. Toffler predicted the imminent arrival of artificial intelligence, cryonics, cloning and robots working behind airline check-in desks
  • Land left Britain. He moved to Taiwan “early in the new millennium”, he told me, then to Shanghai “a couple of years later”. He still lives there now.
  • In a 2004 article for the Shanghai Star, an English-language paper, he described the modern Chinese fusion of Marxism and capitalism as “the greatest political engine of social and economic development the world has ever known”
  • Once he lived there, Land told me, he realised that “to a massive degree” China was already an accelerationist society: fixated by the future and changing at speed. Presented with the sweeping projects of the Chinese state, his previous, libertarian contempt for the capabilities of governments fell away
  • Without a dynamic capitalism to feed off, as Deleuze and Guattari had in the early 70s, and the Warwick philosophers had in the 90s, it may be that accelerationism just races up blind alleys. In his 2014 book about the movement, Malign Velocities, Benjamin Noys accuses it of offering “false” solutions to current technological and economic dilemmas. With accelerationism, he writes, a breakthrough to a better future is “always promised and always just out of reach”.
  • “The pace of change accelerates,” concluded a documentary version of the book, with a slightly hammy voiceover by Orson Welles. “We are living through one of the greatest revolutions in history – the birth of a new civilisation.”
  • Shortly afterwards, the 1973 oil crisis struck. World capitalism did not accelerate again for almost a decade. For much of the “new civilisation” Toffler promised, we are still waiting
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