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"The only constant is change. It's the most basic fact of human existence. Nothing lasts, nothing stays the same. We feel it with each breath. From birth to the unknown moment of our passing, we ride a river of change. And yet, in spite of all evidence to the contrary, we exhaust ourselves in an endless search for solidity. We hunger for something that lasts, some idea or principle that rises above time and change. We hunger for certainty. That is a big problem. It might even be THE problem. Religions are often built around this heartache for certainty. In the face of sickness, loss and grief, a thousand dogmas with a thousand names have risen. Many profess that if only the faithful hold fast to the "rules," the "precepts" or the "doctrine" then certainty can be obtained. Fate and future can be fixed through promises of freedom from immediate suffering, divine favor or everlasting salvation. Scriptures are transformed into unwavering blueprints for an unchanging order. These documents must live beyond question lest the certainty they provide crumble. When human spiritual endeavor devolves into these white-knuckle forms of clinging they become monuments to the fear of change and uncertainty. It would be symmetrical if I could point to science as the pure antidote to the rigid rejection of uncertainty. Science, in the purest forms of its expression as a practice, holds to no doctrine other than that the world might be known. In the ceaseless pursuit of its own questioning path, science asks us to allow for ceaseless change in our ideas, beliefs and opinions. It's this aspect of science that I value more than any other. But science does not exist alone as practice. It's also a constellation of ideas that exist within culture and those ideas can gain value, in and of themselves, without connection to actual practice. In this way science becomes something more and less. For some people the idea of Science offers a trumped up certainty that yields its own false de

"Separating anatomy from what it means to be a man or a woman, New York City is moving forward with a plan to let people alter the sex on their birth certificate even if they have not had sex-change surgery. Under the rule being considered by the city's Board of Health, which is likely to be adopted soon, people born in the city would be able to change the documented sex on their birth certificates by providing affidavits from a doctor and a mental health professional laying out why their patients should be considered members of the opposite sex, and asserting that their proposed change would be permanent. Applicants would have to have changed their name and shown that they had lived in their adopted gender for at least two years, but there would be no explicit medical requirements."

"When high school students in Shanghai crack their history textbooks this fall they may be in for a surprise. The new standard world history text drops wars, dynasties and Communist revolutions in favor of colorful tutorials on economics, technology, social customs and globalization. Socialism has been reduced to a single, short chapter in the senior high school history course. Chinese Communism before the economic reform that began in 1979 is covered in a sentence. The text mentions Mao only once - in a chapter on etiquette. Nearly overnight the country's most prosperous schools have shelved the Marxist template that had dominated standard history texts since the 1950's. The changes passed high-level scrutiny, the authors say, and are part of a broader effort to promote a more stable, less violent view of Chinese history that serves today's economic and political goals. Supporters say the overhaul enlivens mandatory history courses for junior and senior high school students and better prepares them for life in the real world. The old textbooks, not unlike the ruling Communist Party, changed relatively little in the last quarter-century of market-oriented economic reforms. They were glaringly out of sync with realities students face outside the classroom. But critics say the textbooks trade one political agenda for another. They do not so much rewrite history as diminish it. The one-party state, having largely abandoned its official ideology, prefers people to think more about the future than the past."

Isn't this kind of like the reading we had...with the Uncertainty of Knowledge assignment? It talks about how science theories can be true because we believe them to be true, but because time changes and everything is different all the time, they are always easy to be proven wrong, and subject to change. That is like what you said about scientific theories being subject to future questioning. What we perceive to be an atom may not be what Socrates perceived as an atom, or some scientist from year 3000 perceives it. Science is always changing and therefore I agree that the laws that are made are always "refinable".

"Last year's GOP takeover of the U.S. House and statehouses across the country has dramatically changed the shape of the nation's abortion debate. It has also given a boost to an even more far-reaching effort: the push to legally redefine when life itself begins. The question being raised in legal terms is: When does someone become a person? The answer varies under the law. "The definition of personhood ranges if you're talking about property law, or inheritance, or how the census is taken," says Alexa Kolbi-Molinas, an attorney with the American Civil Liberties Union's Reproductive Freedom Project. All those differences are exactly what Keith Mason wants to change. He's president of Personhood USA, a group that's trying to rewrite the laws and constitutions of every state - and some countries - to recognize someone as a person "exactly at creation," he says. "It's fertilization; it's when the sperm meets the egg." Mason says the basic problem is that science has advanced faster than policymaking. "We know, without a shadow of a doubt, when human life begins," he says. "But our laws have not caught up to what we know." And according to his organization, those laws should recognize every fertilized egg as an individual and complete human being."

"A new study uses advanced brain-scanning technology to cast light on a topic that psychologists have puzzled over for more than half a century: social conformity. The study was based on a famous series of laboratory experiments from the 1950's by a social psychologist, Dr. Solomon Asch. In those early studies, the subjects were shown two cards. On the first was a vertical line. On the second were three lines, one of them the same length as that on the first card. Then the subjects were asked to say which two lines were alike, something that most 5-year-olds could answer correctly. But Dr. Asch added a twist. Seven other people, in cahoots with the researchers, also examined the lines and gave their answers before the subjects did. And sometimes these confederates intentionally gave the wrong answer. Dr. Asch was astonished at what happened next. After thinking hard, three out of four subjects agreed with the incorrect answers given by the confederates at least once. And one in four conformed 50 percent of the time. Dr. Asch, who died in 1996, always wondered about the findings. Did the people who gave in to group do so knowing that their answers was wrong? Or did the social pressure actually change their perceptions? "

"Andrew Pole had just started working as a statistician for Target in 2002, when two colleagues from the marketing department stopped by his desk to ask an odd question: "If we wanted to figure out if a customer is pregnant, even if she didn't want us to know, can you do that? " Multimedia How to Break the Cookie Habit This article is adapted from "The Power of Habit: Why We Do What We Do in Life and Business," which will be published on Feb. 28. More in the Magazine » Readers' Comments Share your thoughts. Post a Comment » Read All Comments (35) » Pole has a master's degree in statistics and another in economics, and has been obsessed with the intersection of data and human behavior most of his life. His parents were teachers in North Dakota, and while other kids were going to 4-H, Pole was doing algebra and writing computer programs. "The stereotype of a math nerd is true," he told me when I spoke with him last year. "I kind of like going out and evangelizing analytics." As the marketers explained to Pole - and as Pole later explained to me, back when we were still speaking and before Target told him to stop - new parents are a retailer's holy grail. Most shoppers don't buy everything they need at one store. Instead, they buy groceries at the grocery store and toys at the toy store, and they visit Target only when they need certain items they associate with Target - cleaning supplies, say, or new socks or a six-month supply of toilet paper. But Target sells everything from milk to stuffed animals to lawn furniture to electronics, so one of the company's primary goals is convincing customers that the only store they need is Target. But it's a tough message to get across, even with the most ingenious ad campaigns, because once consumers' shopping habits are ingrained, it's incredibly difficult to change them. There are, however, some brief periods in a person's life when old routines fall apart and

"One of the best aspects of science has always been its readiness to admit when it got something wrong. Theories are constantly being refigured, and new research frequently renders old ideas outdated or incomplete. But this hasn't stopped some discoveries from being hailed as important, game-changing accomplishments a bit prematurely. Even in a field as rigorous and detail-oriented as science, theories get busted, mistakes are made, and hoaxes are perpetrated. The following are ten of the most groundbreaking of these scientific discoveries that turned out to be resting on some questionable data. It is worth noting that most of these concepts are not necessarily "wrong" in the traditional sense; rather, they have been replaced by other theories that are more complete and reliable."

"MID the squawks and pings of our digital devices, the old-fashioned virtues of reading novels can seem faded, even futile. But new support for the value of fiction is arriving from an unexpected quarter: neuroscience. Brain scans are revealing what happens in our heads when we read a detailed description, an evocative metaphor or an emotional exchange between characters. Stories, this research is showing, stimulate the brain and even change how we act in life. Researchers have long known that the "classical" language regions, like Broca's area and Wernicke's area, are involved in how the brain interprets written words. What scientists have come to realize in the last few years is that narratives activate many other parts of our brains as well, suggesting why the experience of reading can feel so alive. Words like "lavender," "cinnamon" and "soap," for example, elicit a response not only from the language-processing areas of our brains, but also those devoted to dealing with smells. In a 2006 study published in the journal NeuroImage, researchers in Spain asked participants to read words with strong odor associations, along with neutral words, while their brains were being scanned by a functional magnetic resonance imaging (fMRI) machine. When subjects looked at the Spanish words for "perfume" and "coffee," their primary olfactory cortex lit up; when they saw the words that mean "chair" and "key," this region remained dark. The way the brain handles metaphors has also received extensive study; some scientists have contended that figures of speech like "a rough day" are so familiar that they are treated simply as words and no more. Last month, however, a team of researchers from Emory University reported in Brain & Language that when subjects in their laboratory read a metaphor involving texture, the sensory cortex, responsible for perceiving texture through touch, became active. Metaphors like "The singer had a velvet vo

"'The most beautiful experience we can have is the mysterious - the fundamental emotion which stands at the cradle of true art and true science.' "We live in a society absolutely dependent on science and technology," Carl Sagan famously quipped in 1994, "and yet have cleverly arranged things so that almost no one understands science and technology. That's a clear prescription for disaster." Little seems to have changed in the nearly two decades since, and although the government is now actively encouraging "citizen science," for many "citizens" the understanding of - let alone any agreement about - what science is and does remains meager. So, what exactly is science, what does it aspire to do, and why should we the people care? It seems like a simple question, but it's an infinitely complex one, the answer to which is ever elusive and contentious. Gathered here are several eloquent definitions that focus on science as process rather than product, whose conduit is curiosity rather than certainty."

"VANDALS have struck a painting that depicts South African President Jacob Zuma with his genitals hanging out. Two men defaced the picture with gobs of paint, as Mr Zuma and his African National Congress sought a court order yesterday to have the painting removed from an art gallery. The case is spiced with freedom of expression on the one hand and the right to dignity on the other. It took centre stage after the painting by Brett Murray went on display in a Johannesburg gallery this month and was reported on in local media. Mr Zuma, who has a reputation for promiscuity, took the depiction of him with his private parts exposed very personally and compared himself to a rape victim. Mr Zuma himself was put on trial for rape, and acquitted, in 2006. "The portrayal has ridiculed and caused me humiliation and indignity," Mr Zuma contended in an affidavit filed yesterday with the South Gauteng High Court in Johannesburg. Presiding over the hearing in a courtroom a few kilometres from the gallery, Judge Fayeeza Kathree-Setiloane said the full three-judge bench should hear the case because the national interest and constitutional issues are at stake. South Africa's constitution protects the right to dignity as well as to freedom of expression. She said the hearing would recommence tomorrow. Mr Zuma and the ANC sought to have the painting, titled "The Spear," removed from the Goodman Gallery and to stop the newspaper City Press from displaying a photo of it on its website. Just before the hearing was scheduled to begin, two men wielding cans of red and black paint calmly walked up to the painting hanging on a gallery wall and took turns defacing it. "Now it's completely and utterly destroyed," said Iman Rappetti, a reporter for a South African TV channel who happened to be on the scene at the time as her camera rolled. Her channel showed a man in a tweed jacket painting a red X over the president's genital area and then his face. Next, a man in a hoodie smeared bl

"Speaking about Britain's Got Talent singer Susan Boyle in October, he said :"She would not be where she is today if it wasn't for the fact that she looked like such a ******* mong." Mong is a slang term used to refer to people with Down's Syndrome. It is derived from the word "mongrel." He went on: "When she first came on the telly, I went: 'Is that a mong?' "I don't mean she has Down's Syndrome, by the way. No, no! That would be offensive. That word doesn't mean that any more." Channel 4 claimed that using the word was justified in the context of late-night humour. It said the comment was not "directed at Susan Boyle as having a disability but at those who refuse to acknowledge that meanings of words can adapt over time". The company said it needed to experiment and defended the entertainer's right to freedom of expression. Ofcom said in its ruling that Gervais was exploring the interpretations and meanings of certain provocative words. He was examining the changes in their associations over time, with a focus on his assertion that the word "mong" had lost its derogatory association with Down's Syndrome. The regulator said: "This involved Ricky Gervais evoking the word's offensiveness to some extent, and challenging the relationship between the offence and the word itself. "We considered, therefore, that the nature and focus of the routine provided a clear editorial context for his use of the term." "

"What can mathematics say about history? According to TED Fellow Jean-Baptiste Michel, quite a lot. From changes to language to the deadliness of wars, he shows how digitized history is just starting to reveal deep underlying patterns. Jean-Baptiste Michel looks at how we can use large volumes of data to better understand our world."

"World-changing theories and big breakthroughs are what every scientist yearns for. But the pressure to get results - and glory - means that feuds come thick and fast"

Try reading a book while doing a crossword puzzle, and that, says author Nicholas Carr, is what you're doing every time you use the Internet. Carr is the author of the Atlantic article Is Google Making Us Stupid? which he has expanded into a book, The Shallows: What the Internet Is Doing to Our Brains. Carr believes that the Internet is a medium based on interruption - and it's changing the way people read and process information. We've come to associate the acquisition of wisdom with deep reading and solitary concentration, and he says there's not much of that to be found online.

"THE Diagnostic and Statistical Manual of Mental Disorders, published by the American Psychiatric Association, is the bible of diagnosis in psychiatry, and is used not just by doctors around the world but also by health insurers. Changing any such central document is complicated. It should therefore come as no surprise that a committee of experts charged with revising the manual has caused consternation by considering removing Asperger syndrome from the next edition, scheduled to appear in 2012. The committee argues that the syndrome should be deleted because there is no clear separation between it and its close neighbor, autism. "

"They and others had been searching for answers and grappling with their implications since Sunday, when Weight Watchers began unveiling its first major overhaul to its cultlike points system, prompting the 750,000 members who attend weekly meetings across the United States - and some one million online adherents - to rethink how they shop, cook and eat. The new plan, company officials say, is based on scientific findings about how the body processes different foods. The biggest change: All fruits and most vegetables are point-free (or free of PointsPlus, as the new program is called). Processed foods, meanwhile, generally have higher point values, which roughly translates to: should be eaten less. "

"Even economists are finally waking up to this fact. A wind of change is now blowing some human spirit back into the ivory towers where economic theory is made. It is becoming increasingly fashionable for economists, especially the younger, more ambitious ones, to borrow insights from psychologists (and sometimes even biologists) to try to explain drug addiction, the working habits of New York taxi-drivers, current sky-high American share prices and other types of behaviour which seem to defy rationality. Alan Greenspan, the chairman of the Federal Reserve, made a bow to this new trend when he wondered about the "irrational exuberance" of American stockmarkets way back in December 1996 (after an initial flutter of concern, investors ignored him). Many economic rationalists still hold true to their faith, and some have fought back by devising rational explanations for the apparent irrationalities studied by the growing school of "behavioural economists". Ironically, orthodox economists have been forced to fight this rearguard action against heretics in their own ranks just as their own approach has begun to be more widely applied in other social sciences such as the study of law and politics. "