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There is a growing community interest in applying Semantic Web and Web 2.0 technologies in health care and life sciences areas including the Health Care and Life Sciences Interest Group (HCLSIG ; http://www.w3.org/2001/sw/hcls/) and Medicine 2.0 (http://www.medicine20congress.com/). This has motivated us to explore how to intersect these two sets of technologies in the context of the HCLS Knowledge Base (KB).

, the government should be a rule-setting referee to encourage the development of an open software platform on which innovators could write electronic health record applications.

The prototype we describe is a biomedical knowledge base, constructed for a demonstration at Banff WWW2007 , that integrates 15 distinct data sources using currently available Semantic Web technologies such as the W3C standard Web Ontology Language [OWL] and Resource Description Framework [RDF]. This report outlines which resources were integrated, how the knowledge base was constructed using free and open source triple store technology, how it can be queried using the W3C Recommended RDF query language SPARQL [SPARQL], and what resources and inferences are involved in answering complex queries. While the utility of the knowledge base is illustrated by identifying a set of genes involved in Alzheimer's Disease, the approach described here can be applied to any use case that integrates data from multiple domains.

You'd think being seriously wounded on the battlefield would be the most painful thing a soldier could go through, but the recovery from burns can take months of agonizing physical therapy that prolongs the suffering. In some cases, healing can be more painful than the original trauma. What if you could take patients away from their immediate surroundings when cleaning their burns or stretching the skin during physical therapy? A virtual reality game created to help patients deal with pain hopes to do just that.

The OpenKnowledge team responded to the UK's Grand Challenge Project for information-driven healthcare with a proposal to "completely change the way patients view the management of their healthcare pathways."