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Nathan Goodyear

International Journal of Obesity - Antiobesity action of peripheral exenatide (exendin-4) in rodents: effects on food intake, body weight, metabolic status and side-effect measures - 0 views

www.nature.com/...0803284a.html

exanatide Byetta obesity fatty liver weight loss

shared by Nathan Goodyear on 06 Apr 11 - No Cached
  • Systemic exenatide reduces body weight gain in normal, high-fat-fed rodents
  • role in metabolic pathways mediating food intake.
  • the first of which to be identified was an enhancement of glucose-dependent insulin secretion
  • ...5 more annotations...
  • limits glucose appearance via glucose-dependent slowing of gastric emptying
  • suppression of inappropriately elevated postprandial glucagon secretion
  • promote pancreatic -cell proliferation and islet cell neogenesis in both animal and in vitro studies
  • short-term regulator of food intake
  • eceptor agonism in satiety
  • Nathan Goodyear on 06 Apr 11
     
    exanatide helps in obesity and fatty liver treatment
Nathan Goodyear

Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus - 0 views

www.ajhp.org/...173.short

exenatide byetta diabetes overweight obesity pharmacodynamics pharmacokinetics

shared by Nathan Goodyear on 06 Apr 11 - No Cached
  • exenatide dose-dependently reduced postprandial plasma glucose excursion by insulinotropism
  • suppression of plasma glucagon, and slowing of gastric emptying.
  • Nathan Goodyear on 06 Apr 11
     
    exenatide improves insulin/glucose regulation
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