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wheelchairindia9

Round Ring Pillow For Bed Sores - 0 views

www.wheelchairindia.com/...ound-Ring-Pillow-For-Bed-Sores

Round Ring Pillow For Bed Sores bed sores bedsore ring pillow pillow for bed sores bedsore pillow round ring pillow pillows to prevent bed sores bed sores pillows vissco round ring pillow

shared by wheelchairindia9 on 24 Feb 16 - No Cached
  • wheelchairindia9 on 24 Feb 16
     
    Round Ring Pillow providing effective relief to pressure sores, the rendered round ring pillow is procured from reliable source. In additions to this, the round ring pillow provides effective cushioned seating and effectively enhances the healing process. Round Ring Pillow Specifications Provideds relief to pressure sores. Provides orthopaedic cushioned seating and encourages healing. Construction with soft PVC material. Maximum weight of patient 75kgs. Round Ring Pillow Features Provides even weight bearing Renders stability while seating Easy to use
wheelchairindia9

Comfort And Ease Lightweight Wheelchair - 0 views

onlywheelchair.blogspot.in/...se-lightweight-wheelchair.html

Comfort And Ease Lightweight Wheelchair Transport Chair Light Wheelchairs transport wheelchair Ultra Lightweight Wheelchair Lightweight Wheelchair Travel Wheelchair Karma Travel Wheelchair KM TV 20.2

shared by wheelchairindia9 on 07 Dec 15 - No Cached
  • wheelchairindia9 on 07 Dec 15
     
    Transport Chair weighs only 14.8 lbs - almost 25% lighter than standard folding transport chairs. The Chair also features breathable nylon upholstery, an attractive colored frame and comfortable, "restaurant-style" arms - so it can pull up to tables and eat comfortably. The chair not only has a fold-down back but is foldable for length-wise for easy transport. The backside of the chair contains a key ring and multiple pockets. Transport chairs make it easier for the loved ones and caregivers to help to get around in comfort and ease. Compared to a standard wheelchair, a transport chair requires a caregiver to push the chair. A transport wheelchair is much lighter than a wheelchair; plus, it is more compact which makes getting around town easier. This chair comes equipped with loop-lock hand brakes that are easy to operate and ideal for locking the rear wheels during transfers. It also has a seatbelt which keeps the passenger securely in place and it is compact when folded making it easy to lift into a car or carry up the stairs. It is equipped with a seat belt, comfortable nylon upholstery, full length permanent armrest, and detachable footrests. It has a 19 inch wide seat that can provide and a weight capacity of 300 pounds. Karma Travel Wheelchair KM TV 20.2: Karma Travel Wheelchair KM TV 20.2 - 606 T-6 aircraft-grade aluminum-alloy frame provides incredible strength. Easy-to-fold in three seconds. Karma Travel Wheelchair KM TV 20.2 Features: Type: Travel Wheelchair T-6 aircraft-grade aluminum Secure brake improve safety Padded flip back armrest PU front caster & rear wheel Karma Travel Wheelchair KM TV 20.2 Measurements: Weight: 8.9kg Seat width: 39.5cm Tyre: PU front casters and rear wheels Capacity: 100kg Folded size: (L/W/H): 610mm x 350mm x710mm. Ultra Lightweight Wheelchair: Its compact design and feather light weight makes it suitable for people on the go. Ultra Lightweight Wheelchair Specifications: Frame Style : Foldabl
wheelchairindia9

Tynor Compression Stocking Below Knee - 0 views

www.wheelchairindia.com/...ompression-Stocking-Below-Knee

Tynor Compression Stocking Below Knee Compression Stocking Below Knee Compression Stocking knee compression stockings price compression stockings india compression stockings buy

shared by wheelchairindia9 on 04 Apr 16 - No Cached
  • wheelchairindia9 on 04 Apr 16
     
    Tynor Compression Stocking Below Knee Compression Stockings provide controlled compression to the legs to squeeze away abnormal back flow of blood into the superficial veins that lie just beneath the surface of the skin from the perforating veins. It is used in all forms of venous disease including blood pools or congests in legs. Severe varicose veins and discoloration to sores, ulcers and potentially life-threatening blood clots. Light weight. Four way stretch. Freely breathable. Soft and comfortable. Tynor Compression Stocking Below Knee Features Made from soft nylon yarn and spandex Strong and durable. Dermophillic. Optimal compression. Excellent aesthetics. Excellent Color fastness. Four-way stretchability Offers optimal compression. Snug fitting. Double layered Retains body heat effectively. Provides therapeutic warmth. Quicker healing. Strong and durable. Tapered shape and Controlled compression Uniform compression even on uneven limb surface. Offers graded compression high to low from toe upwards. Effective blood evacuation. Open toe design Reduces wear and tear. Easy to wear. Compatible to toe rings or other jewelry items. Tynor Compression Stocking Below Knee Measurements
snfilms

Music Video Of Ariana Grande - 0 views

Sdtunes MusicVideo ArianaGrande

shared by snfilms on 07 Apr 21 - No Cached
  • snfilms on 07 Apr 21
     
    Check out #ArianaGrande 7 rings and more #musicvideo on #sdtunes http://www.sdtunes.com/.../ariana-grande-huge-hit-music...
wheelchairindia9

Best Wheelchair For Heavy Person - 0 views

disabilityproduct.in/...HEAVY-DUTY-WHEELCHAIR

Take Safer Shower with a Shower Commode Stool or Chair safely and comfortably provide comfortable and ergonomic support convenient and secure facility easy to keep clean removable or swing away armrests

shared by wheelchairindia9 on 05 Aug 15 - No Cached
  • wheelchairindia9 on 05 Aug 15
     
    People who are very large or heavy may have difficulty using regular chairs. In some cases, they are simply too wide to comfortably fit in an average-sized chair, and in other cases their weight may damage or break the chair entirely. This is not only humiliating to the person who sits in the chair, but could result in injury if the chair collapses. To avoid such an unfortunate occurrence as well as potential litigation, it is important to purchase heavy duty chairs that can accommodate larger family members, employees, and customers. Heavy duty wheelchairs can also be made for specific purposes. An off-road wheelchair, for example, is a heavy duty wheelchair designed for individuals who intend on spending a lot of time on rugged terrain. The most common type of heavy duty wheelchair is a bariatric wheelchair, which is designed to allow larger individuals adequate mobility. For this matter, heavy duty wheelchairs typically have larger seats than conventional wheelchairs. The frames of these wheelchairs can be made from several different reinforced metals, although a titanium wheelchair is often the most popular choice. The wheels themselves are made of thicker rubber than normal, preventing any possible failure due to the greater amount of weight supported. Most makes of heavy duty wheelchairs fold like regular wheelchairs, making storage relatively easy despite the wheelchair's increased size. For the user's convenience, a heavy duty wheelchair can either be manually-operated or motorized, each with its own pros and cons. A manual Heavy Duty Wheelchair gives full control of motion to the user, but the added weight from the reinforcements makes pushing or propelling the wheelchair much harder than normal. A motorized heavy duty wheelchair offers a solution to this dilemma, but is often more expensive and harder to maintain than a manual wheelchair. Some designs offer a combination of both, with a small motor assisting those pushing the wheelchair. The proper c
trungtamnamkhoa

Learn More About Foreskin Disease - Men's Health Clinic In Viet Nam - 1 views

menhealth.vn/-de-muon-thuo-cua-dang-may-rau

cancer hormone Testosterone Men health healthy Foreskin Disease

shared by trungtamnamkhoa on 25 Jun 19 - No Cached
  • trungtamnamkhoa on 25 Jun 19
     
    Semi-glans It is a situation in which the boy is still "open his eyes" but is either very difficult or painful or requires the help of slipping from the homeowner. Having opened the eyes is not necessarily good in this case because soon enough the foreskin will form a tightening ring just below, obstructing the healed blood, leading to edema, and when the penis is hard, everything even worse.
Nathan Goodyear

Oncotarget | NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Id... - 0 views

www.oncotarget.com/index.php

vitamin C IV vitamin C cancer cancer stem cells milk thistle silymarin ascorbic acid bee propolis CAPE glycolytic inhibitor natural

shared by Nathan Goodyear on 08 Dec 17 - No Cached
  • Vitamin C was ~10 times more potent than 2-DG for the targeting of CSCs
  • Cancer stem-like cells (CSCs) are thought to be the root cause of chemotherapy-resistance and radio-resistance
  • ultimately leading to treatment failure in patients with advanced disease [1-3]. They have been directly implicated mechanistically in tumor recurrence and metastasis, resulting in poor patient survival
  • ...26 more annotations...
  • mitochondrial biogenesis may be a key driver of the CSC phenotype
  • Our results indicate that increased mitochondrial oxidative stress and high NADH levels are both key characteristics of the CSC metabolic phenotype
  • high levels of NAD(P)H auto-fluorescence are known to be a surrogate marker for mitochondrial “power”, high OXPHOS capacity and increased ATP production
  • CSCs may be strictly dependent on NAD(P)H to maintain their enhanced mitochondrial function
  • an intact NAD+ salvage pathway is strictly required for mammosphere formation, supporting our results using NAD(P)H auto-fluorescence, which enriched CSC activity by more than 5-fold.
  • Since glycolysis is especially critical for maintaining the TCA cycle, OXPHOS and overall mitochondrial function, we next assessed the effects of known glycolytic inhibitors
  • we show that two other natural products that function as effective glycolysis inhibitors, also inhibited mammosphere formation. More specifically, vitamin C (ascorbic acid), which induces oxidative stress and inhibits the activity of GAPDH (a key glycolytic enzyme) [17], also inhibited mammosphere formation, with an IC-50 of 1 mM (Figure 7B). Therefore, vitamin C was ~10 times more potent than 2-DG at targeting CSC propagation
  • silibinin (the major active constituent of silymarin, an extract of milk thistle seeds) [18], which specifically functions as an inhibitor of glucose uptake, blocked mammosphere formation, with an IC-50 between 200 and 400 µM
  • caffeic acid phenyl ester (CAPE), a key component of honey-bee propolis, has potent anti-cancer properties
  • Propolis has a strong history of medicinal use, dating back more than 2,000 years
  • Because of it aromatic ring structure (Figure 8), we speculated that CAPE might function as a potent inhibitor of oxidative mitochondrial metabolism
  • CAPE quantitatively inhibits the mitochondrial oxygen consumption rate (OCR) and, in turn, induces the onset of aerobic glycolysis (ECAR)
  • CAPE shows a clear selectivity for targeting CSCs and adherent cancer cells, relative to normal fibroblasts.
  • CAPE functions as a “natural” mitochondrial OXPHOS inhibitor, that preferentially targets the CSC sub-population. This could explain CAPE’s known anti-cancer properties
  • Our data directly shows that a small fraction of the total cell population, characterized by increased PGC1α activity, high mitochondrial ROS/H2O2 and high NADH levels, has the ability to survive and grow under anchorage-independent conditions, driving mammosphere formation
  • We highlight the utility of certain natural products, such as Silibinin, Vitamin C and CAPE, that could be used to therapeutically target CSCs. Silibinin is the major active component of silymarin, which is an extract prepared from milk thistle seeds.
  • high NADH is a property that is conserved between normal and cancerous stem cells
  • Previous studies have also shown that when non-CSCs and CSCs are both fed mitochondrial fuels (such as L-lactate or ketone bodies), that CSCs quantitatively produce more NADH in response to this stimulus
  • CSCs may be strictly dependent on NADH to maintain their enhanced mitochondrial function
  • The Noble Prize winner, Linus Pauling, was among the first to describe and clinically test the efficacy of Vitamin C, as a relatively non-toxic anti-cancer agent
  • Vitamin C has two mechanisms of action. First, it is a potent pro-oxidant, that actively depletes the reduced glutathione pool, leading to cellular oxidative stress and apoptosis in cancer cells. Moreover, it also behaves as an inhibitor of glycolysis, by targeting the activity of GAPDH, a key glycolytic enzyme.
  • Here, we show that Vitamin C can also be used to target the CSC population, as it is an inhibitor of energy metabolism that feeds into the mitochondrial TCA cycle and OXPHOS
  • Vitamin C may prove to be promising agent for new clinical trials, aimed at testing its ability to reduce CSC activity in cancer patients, as an add-on to more conventional therapies, to prevent tumor recurrence, further disease progression and metastasis
  • Interestingly, a breast cancer based clinical study has already shown that the use of Vitamin C, concurrent with or within 6 months of chemotherapy, significantly reduces both tumor recurrence and patient mortality
  • CAPE quantitatively reduces mitochondrial oxygen consumption (OCR), while inducing a reactive increase in glycolysis (ECAR). As such, it potently inhibits mammosphere formation with an IC-50 of ~2.5 µM. Similarly, it also significantly inhibits cell migration
  • we also demonstrate that 7 different inhibitors of key energetic pathways can be used to effectively block CSC propagation, including three natural products (silibinin, ascorbic acid and CAPE). Future studies will be necessary to test their potential for clinical benefit in cancer patients.
  • Nathan Goodyear on 08 Dec 17
     
    The future of cancer therapy is cancer stem cells.  Study finds that Vitamin C, silymarin, and bee propolis blocks mitochondrial energy pathways in cancer stem cells.  Vitamin C is a known glycolytic inhbitor. Vitamin C was found to inhibit glycolysis via GAPDH targeting to inhibit the energy pathways of the mitochondria in CSCs.  The authors propse that Vitamin C can be used as add on therapies for conventional therapies to specifically attack the CSCs and their contribution to recrurence, treatment resistance, and metastasis potential all in addition to the ability of vitamin C to reduce the side effects of chemotherapy.
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