Telomere shortening and ageing of the immune system | Mendeley - 0 views
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The immune system is highly sensitive to shortening of telomeres
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they can up-regulate telomerase, the telomere extending enzyme
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In ageing immune system adaptive immunity deteriorates because of a progressive decline of naive T and B cells and decrease of absolute numbers of T and B lymphocytes
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the immune system is very sensitive to shortening of telomere length. This change in the immune system can be a pivotal role in disease development