Study finds that acetyl-11-keto-Beta-boswellic acid (AKBA) reduced growth of pancreatic cancer and metastasis in mouse model. AKBA also inhibits NF-kappaB and induced apoptosis. AKBA is found in Frankinsense.
Boswellic acid shown to have systemic anti-inflammatory effects through topical application. This study only looked at Boswellia Serrata and it's triterpenes. The different Boswellia have different levels of AKBA, BA, and BKA.
Study questions the 5-LOX inhibition as the mechanism of action of Boswellia due to its low absorption. However, prostaglandin E production was inhibited. Both have profound antiiflammatory effects and would benefit chronic inflammatory diseases.
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