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Nathan Goodyear

An Empirical Evaluation of Guidelines on Prostate-specific Antigen Velocity in Prostate... - 0 views

www.ncbi.nlm.nih.gov/...PMC3057983

PSA psa velocity prostate cancer

shared by Nathan Goodyear on 20 Dec 15 - No Cached
  • men with a high PSA velocity (rate of change of PSA level)—greater than 0.35 ng mL−1 y−1—should consider biopsy even if absolute level of PSA is very low.
  • like other authors, we found strong evidence for a univariate association between PSA velocity and positive biopsy
  • we also found that PSA velocity does not add important predictive value to PSA and other standard predictors; in other words, we did not find that the use of a PSA velocity criterion for biopsy would improve clinical decision making
  • Nathan Goodyear on 20 Dec 15
     
    This is the study that many have used to discredit psa velocity, but that is cherry picking the authors conclusions.  The authors did find an association with a positive psa velocity and + prostate biopsy.  Not useless, but useful in the right context.
Nathan Goodyear

What is the possible role of PSA doubling time (PSADT) and PSA velocity (PSAV) in the d... - 0 views

www.ncbi.nlm.nih.gov/...PMC3921716

prostate cancer PSA PSADT PSA velocity

shared by Nathan Goodyear on 03 Jun 18 - No Cached
  • (11)C]choline PET/CT
  • PSA velocity (PSAV)
  • PSA doubling time (PSADT)
  • ...1 more annotation...
  • The most important premise stemming from this bibliographical review is that patients with short PSADT should constitute a group in which hormonal therapy should be considered, while patients with long PSADT should be destined for salvage RT
  • Nathan Goodyear on 03 Jun 18
     
    Review of PSA doubling time (PSADT) and PSA velocity in the aid in therapy of prostate cancer.
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