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Congenital insensitivity to pain (CIP) is a rarely syndrome and is characterized by unresponsiveness to painful stimulants, anhydrous, mental retardation, and recurring feverish episodes. In this case report we presented our anesthesia management in a patient with congenital insensitivity to pain for lower extremity surgery due to osteomyelitis. For more details : http://scidoc.org/IJAR-2332-2780-04-1001.php

Most postsurgical patients experience moderate to severe acute pain which, in some patients, transitions to chronic postsurgical pain (CPSP). Optimal pain control of acute surgical pain will likely blunt or prevent the transition of acute postsurgical pain (APSP) to CPSP. While there are known risk factors for such chronification of pain type, and certain surgeries (such as limb amputation) and approaches (open versus laparoscopic) are associated with higher rates, it is impossible to predict which patients will transition to CPSP. Additionally, despite knowledge and an armamentarium of analgesics, APSP may be suboptimally controlled.

International Journal of Clinical & Experimental Otolaryngology (IJCEO) is a comprehensive, peer reviewed journal devoted to Clinical and Experimental Otolaryngology. publishes original research, latest developments, review papers, scientific data, editorials from leading scientists and scholars around the world.

The association of Human papillomavirus (HPV ) and P16INK4A is well established with cervical malignancies and has been studied in oral mucosa also. Koilocytosis, that is considered to be a hallmark of HPV infection is also seen in oesophageal mucosa. For more info : http://scidoc.org/IJVSR-2330-0027-04-402.php