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Medicines and healthcare are synonymous globally. As treatments become more innovative, to address unmet clinical needs, it is important that there is innovation in the pharma value chain as well. In order that patients receive the right medicine, at the right time and the right place, there is a need for a complex value chain. The full set of activities that occur prior to a patient receiving a medicine, constitute the pharmaceutical value chain. This value would differ within markets and also between markets. https://www.acldigital.com/blogs/top-10-data-integration-and-management-challenges-pharma-value-chain

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Organic compounds of unexpected complexity exist throughout the universe, Prof. Sun Kwok and Dr. Yong Zhang of the University of Hong Kong have discovered, suggesting that complex organic compounds can be synthesized in space even when no life forms are present. The organic substance they found contains a mixture of aromatic (ring-like) and aliphatic (chain-like) components that are so complex, their chemical structures resemble those of coal and petroleum. Since coal and oil are remnants of ancient life, this type of organic matter was thought to arise only from living organisms. Unidentified radiation from the universe The researchers investigated an unsolved phenomenon: a set of infrared emissions detected in stars, interstellar space, and galaxies, known as "Unidentified Infrared Emission features." From observations taken by the Infrared Space Observatory and the Spitzer Space Telescope, Kwok and Zhang showed that the astronomical spectra have chemical structures that are much more complex that previously thought. By analyzing spectra of star dust formed in exploding stars called novae, they show that stars are making these complex organic compounds on extremely short time scales of weeks, and ejecting it into the general interstellar space, the region between stars. "Our work has shown that stars have no problem making complex organic compounds under near-vacuum conditions," says Kwok. "Theoretically, this is impossible, but observationally we can see it happening." Most interestingly, this organic star dust is similar in structure to complex organic compounds found in meteorites. Since meteorites are remnants of the early Solar System, the findings raise the possibility that stars enriched the early Solar System with organic compounds. The early Earth was subjected to severe bombardments by comets and asteroids, which potentially could have carried organic star dust. Whether these delivered organic compounds played any role in the development of l

An asteroid strike may not only account for the demise of ocean and land life 65 million years ago, but the fireball's path and the resulting dust, darkness and toxic metal contamination may explain the geographic unevenness of extinctions and recovery, according to Penn State geoscientists.