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Mars Base

Bacteria-eating viruses 'magic bullets in the war on superbugs' - 0 views

www.sciencedaily.com/...131016212558.htm

scibyte107 ViewerFeedback

shared by Mars Base on 27 Oct 13 - No Cached
  • A specialist team of scientists from the University of Leicester has isolated viruses that eat bacteria -- called phages -- to specifically target the highly infectious hospital superbug Clostridium difficile
  • predominantly been funded by the Medical Research Council (MRC).
  • been investigating an alternative approach to antibiotics, which utilizes naturally occurring viruses called bacteriophages, meaning 'eaters of bacteria'.
  • ...24 more annotations...
  • since the discovery of the first antibiotic, penicillin, antibiotics
  • have saved countless lives and impacted on the well-being of humanity
  • the future impact of antibiotics is dwindling
  • with more and more bacteria
  • 'out-evolving' these miracle drugs
  • bacteriophages
  • are specific in what they kill and will generally only infect one particular species, or even strain, of bacteria
  • Following attachment to their hosts, they inject their DNA into the bacterium, which then replicates many times over, ultimately causing the bacterial cell to burst open
  • team have
  • , a specific mixture of phages have been proved, through extensive laboratory testing, to be effective against 90% of the most clinically relevant C. diff strains currently seen in the U.K
  • US-based biopharmaceutical company and pioneers in developing phage-based therapeutics
  • have already made progress in developing phages targeted against Pseudomonas aeruginosa, a pathogen that causes acute, life-threatening lung infections in cystic fibrosis patients
  • funding further development and testing
  • phages developed
  • is to have a phage mixture ready to go into phase 1 and 2 clinical trials
  • Evaluations of the efficacy of bacteriophage therapy and optimisation of dosing regimes will be carried out
  • bacteria primarily affect our digestive system
  • pose a serious threat when our natural digestive environment is disrupted or depleted, such as after chronic antibiotic use
  • antibiotics also destroy the 'good' gut bacteria, in turn increasing the potential for relapse or new infections
  • The key advantage of using phages over antibiotics
  • A phage will infect and kill only a specific strain/species of bacteria.
  • Antibacterial resistance is a major and growing threat to health globally
  • This study
  • examines a new way to kill bacteria to circumvent resistance formation
Mars Base

Russia finds 'new bacteria' in Antarctic lake - 0 views

phys.org/...a-bacteria-antarctic-lake.html

scibyte85 SubglacialLake

shared by Mars Base on 08 Mar 13 - No Cached
  • Russian scientists believe they have found a wholly new type of bacteria in the mysterious subglacial Lake Vostok in Antarctica
  • The samples obtained from the underground lake in May 2012 contained a bacteria which bore no resemblance to existing type
  • "After putting aside all possible elements of contamination, DNA was found that did not coincide with any of the well-known types in the global database,"
  • ...13 more annotations...
  • discovery comes from samples collected in an expedition in 2012 where a Russian team drilled down to the surface of Lake Vosto
  • believed to have been covered by ice for more than a million years but has kept its liquid state.
  • Lake Vostok is the largest subglacial lake in Antarctica
  • The Russian team last year drilled almost four kilometres (2.34 miles) to reach the lake and take the samples.
  • t the interest surrounded one particular form of bacteria whose DNA was less than 86 percent similar to previously existing forms.
  • "In terms of work with DNA this is basically zero. A level of 90 percent usually means that the organism is unknown."
  • not even possible to find the genetic descendants of the bacteria.
  • "If this had been found on Mars everyone would have undoubtedly said there is life on Mars. But this is bacteria from Earth."
  • new samples of water would be taken from Lake Vostok during a new expedition in May.
  • "If we manage to find the same group of organisms in this water we can say for sure that we have found new life on Earth that exists in no database,"
  • Exploring environments such as Lake Vostok allows scientists to discover what life forms can exist in the most extreme conditions
  • whether life could exist on some other bodies in the solar system.
  • Saturn's moon Enceladus and the Jupiter moon Europa as they are believed to have oceans, or large lakes, beneath their icy shells.
Mars Base

Fear of Komodo dragon bacteria wrapped in myth - 0 views

phys.org/...modo-dragon-bacteria-myth.html

scibyte100

shared by Mars Base on 01 Jul 13 - No Cached
  • It has long been believed that Komodo dragon bites were fatal because of toxic bacteria in the reptiles' mouths
  • But ground-breaking research
  • has found that the mouths of Komodo dragons are surprisingly ordinary and the levels and types of bacteria do not differ from any other carnivore
  • ...3 more annotations...
  • Unlike people have been led to believe, they do not have chunks of rotting flesh from their meals on their teeth, cultivating bacteria
  • the poor hygiene of water buffalo is responsible for perceptions about deadly toxic bacteria in the dragons
  • They now populate the islands of Indonesia where they prey on the introduced water buffalo, and on pigs and deer
Mars Base

Gut microbes may be behind weight loss after gastric bypass | Genes & Cells | Science News - 0 views

www.sciencenews.org/...ight_loss_after_gastric_bypass

scibyte88 WeightLoss

shared by Mars Base on 28 Mar 13 - No Cached
  • Roux-en-Y, the most common technique for gastric bypass, diverts food around most of the stomach and upper small intestine
  • Previous studies of people and rats have found that the natural mix of microbes in the intestines changes after gastric bypass, with some groups growing more prominent and others diminishing in number
  • No one knew whether the altered microbial composition was merely a side effect of the surgery, or whether shifting bacterial populations could help people lose weight.
  • ...13 more annotations...
  • To find out
  • fattened up mice then performed either bypass or a sham surgery on the animals
  • Mice in the bypass group lost about 29 percent of their body weight within three weeks of the procedure
  • even before the mice dropped weight, those in the bypass group already had an altered mix of intestinal bacteria
  • Compared with the sham operation group, the bypass mice had more of certain types of microbes
  • Some species of
  • are pathogens, but others help prevent inflammation and maintain intestinal health
  • Bypass mice also had more
  • bacteria, which can feed on mucus lining the intestines, particularly when the host is cutting calories
  • researchers speculate that the microbes somehow trigger fat-burning changes in the host’s metabolism
  • Then the researchers transplanted bacteria from the intestines of bypass mice into mice that had been raised without any bacteria
  • The formerly germ-free mice slimmed down, trimming about 5 percent of their body weight, even though they started out lean
  • Germ-free mice that received bacteria from the guts of sham surgery mice actually packed on a bit of fat
Mars Base

First Evidence of Life in Antarctic Subglacial Lake : The Crux - 0 views

blogs.discovermagazine.com/...e-in-antarctic-subglacial-lake

scibyte80 AntarcticLake

shared by Mars Base on 01 Feb 13 - No Cached
  • The search continues for life in subglacial Lake Whillans, 2,600 feet below the surface of the West Antarctic Ice Sheet—but a thrilling preliminary result has detected signs of life
  • At 6:20am on January 28, four people in sterile white Tyvek suits tended to a winch winding cable onto the drill platform
  • One person knocked frost off the cable as it emerged from the ice borehole a few feet below
  • ...24 more annotations...
  • a gray plastic vessel, as long as a baseball bat, filled with water from Lake Whillans, half a mile below.
  • The bottle was hurried into a 40-foot cargo container outfitted as a laboratory on skis
  • Some of the lake water was squirted into bottles of media in order to grow whatever microbes might inhabit the lake
  • cultures could require weeks to produce results
  • When lake water was viewed under a microscope, cells were seen: their tiny bodies glowed green in response to DNA-sensitive dye. It was the first evidence of life in an Antarctic subglacial lake.
  • (A Russian team has reported that two types of bacteria were found in water from subglacial Lake Vostok, but DNA sequences matched those of bacteria that are known to live inside kerosene—causing the scientists to conclude that those bacteria came from kerosene drilling fluid used to bore the hole, and not from Lake Vostok itself
  • In order to conclusively demonstrate that Lake Whillans harbors life, the researchers will need to complete more time-consuming experiments showing that the cells actually grow
  • dead cells can sometimes show up under a microscope with DNA-sensitive
  • weeks or months will pass before it is known whether these cells represent known types of microbes, or something never seen before
  • t a couple of things seem likely. Most of those microbes probably subsist by chewing on rocks. And despite being sealed beneath 2,600 feet of ice, they probably have a steady supply of oxygen.
  • oxygen comes from water melting off the base of the ice sheet—maybe a few penny thicknesses of ice per year
  • When you melt ice, you’re liberating the air bubbles [trapped in that ice
  • That’s 20 percent oxygen
  • , lake bacteria could live on commonly occurring pyrite minerals that contain iron and sulfur
  • would obtain energy by using oxygen to essentially “burn” that iron and sulfur (analogous to the way that animals use oxygen to slowly burn sugars and fats).
  • The half mile of glacial ice sitting atop Lake Whillans is quite pure—derived from snow that fell onto Antarctica thousands of years ago.
  • contains only one-hundredth the level of dissolved minerals that are seen in a clear mountain creek, or in tap water from a typical city
  • a sensor lowered down the borehole this week showed that dissolved minerals were far more abundant in the lake itself
  • The fact that we see high concentrations is suggestive that there’s some interesting water-rock-microbe interaction that’s going on
  • Microbes, in other words, might well be munching on minerals under the ice sheet
  • will take months or years to unravel this picture
  • will perform experiments to see whether microbes taken from the lake metabolize iron, sulfur, or other components of minerals
  • will analyze the DNA of those microbes to see whether they’re related to rock-chewing bacteria that are already known to science.
  • Antarctica isn’t the only place in the solar system where water sits concealed in the dark beneath thick ice. Europa and Enceladus (moons of Jupiter and Saturn, respectively) are also thought to harbor oceans of liquid water. What is learned at Lake Whillans could shed light on how best to look for life in these other places
Mars Base

Amber discovery indicates Lyme disease is older than human race - 0 views

phys.org/...covery-lyme-disease-older.html

scibyte133 LymeDidease

shared by Mars Base on 31 May 14 - No Cached
  • Lyme disease is a stealthy, often misdiagnosed disease that was only recognized about 40 years ago
  • new discoveries of ticks fossilized in amber show that the bacteria which cause it may have been lurking around for 15 million years
  • The findings were made
  • ...13 more annotations...
  • studied 15-20 million-year-old amber
  • that offer the oldest fossil evidence ever found of Borrelia, a type of spirochete-like bacteria that to this day causes Lyme disease
  • In a related study
  • scientists announced the first fossil record of Rickettsial-like cells, a bacteria that can cause various types of spotted fever
  • it's worth considering that these tick-borne diseases may be far more common than has been historically appreciated
  • Those fossils from Myanmar were found in ticks about 100 million years old.
  • plant and animal life forms found preserved in amber
  • are very efficient at maintaining populations of microbes in their tissues, and can infect mammals, birds, reptiles and other animals
  • "In the United States, Europe and Asia, ticks are a more important insect vector of disease than mosquitos
  • A series of four ticks from Dominican amber were analyzed in this study
  • In a separate report, Poinar found cells that resemble Rickettsia bacteria, the cause of Rocky Mountain spotted fever and related illnesses
  • This is the oldest fossil evidence of ticks associated with such bacteria
  • Evidence suggests that dinosaurs could have been infected with Rickettsial pathogens
Mars Base

Breath Test Could Sniff Out Infections in Minutes | Observations, Scientific American B... - 0 views

blogs.scientificamerican.com/...niff-out-infections-in-minutes

scibyte77 MedicalDevice

shared by Mars Base on 12 Jan 13 - No Cached
  • Researchers have developed a test that can detect the presence of common infectious bacteria based just on the breath
  • The test picks up signature volatile organic compound (VOC)—particles emitted in gasses—profiles that the bacteria produce that are distinct those that the body—or other bacteria—give off
  • researchers
  • ...9 more annotations...
  • conducted the studies in lab mice that were infected with different types of common bacteria
  • two different strains of Pseudomonas aeruginosa, which can cause pneumonia, and one strain of Staphylococcus aureus, which can cause respiratory infections
  • The next day, the researchers tested the animals’ breath by ionizing breath samples then shooting them through a mass spectrometer to analyze concentrations of various VOCs in a process called secondary electrospray ionization mass spectrometry
  • The test detected the different bacterial infections as well as differentiated between healthy and infected
  • also located the difference between the two strains of P. aeruginosa
  • technique will have to be tested in large human trials before it makes an appearance in the clinic
  • the rapidity of the test is appealing. And it could at least make it a good first step in detecting bacterial infections, with a follow-up culture coming later if deemed necessary—to detect drug-resistant TB, for example
  • suspect that we will also be able to distinguish between bacterial, viral and fungal infections of the lung
  • Similar breath tests have also been studied for detecting other ailments, such as diabetes and cancer
Mars Base

Tiny Sponge Soaks Up Venom in Blood: Scientific American - 0 views

www.scientificamerican.com/article.cfm

scibyte92 MedicalTreatment

shared by Mars Base on 27 Apr 13 - No Cached
  • A tiny sponge camouflaged as a red blood cell could soak up toxins ranging from anthrax to snake venom, new research suggests
  • The new "nanosponge,"
  • The nanoparticles, also called nanosponges, act as decoys that lure and inactivate the deadly compounds
  • ...17 more annotations...
  • When injected into mice, the tiny decoys protect mice against lethal doses of a toxin produced by methicillin-resistant Staphylococcus aureus, or MRSA.
  • Follow-up studies need to be done in humans
  • One of the mainstay strategies of bacteria and poison is to poke holes in cells, disrupting their internal chemical balance and causing them to burst
  • far, researchers haven't had much success creating all-purpose treatments to exploit this vulnerability
  • researchers created a tiny spherical core of a lactic acid byproduct, which forms naturally during metabolism in the human body
  • They then wrapped the cores in the outer surface of red blood cells. (To get the outer skin of red blood cells, they used a difference in particle concentration inside and outside the cells to cause them to burst, and then collected their outer membranes
  • The entire ensemble became a tiny nanosponge, which was about 85 nanometers in diameter, or 100 times smaller than a human hair
  • In cell cultures, the camouflaged sponges act as decoys, luring the toxins from
  • the bacteria that causes strep throat) and bee venom
  • then binding to the structure the "poisons" normally use to poke through cells
  • When they stick onto the nanosponge, that particular damaging structure gets preoccupied, and then the body can digest the entire particle
  • the team injected 18 mice with a lethal dose of a MRSA toxin. Half the mice then got a dose of the nanosponges
  • Whereas all the mice in the control group died, all but one that received the treatment survived
  • Because so many bacteria use the same pore-forming strategy, the nanosponges could be used as a universal treatment option when doctors don't know exactly what is causing an illness
  • The sponges' tiny size means a small amount of blood, for camouflage, can be used to make an effective dose
  • also allows them to circulate freely through blood vessels, lure enough of the toxins to have an impact and still be degraded safely
  • the researchers want to see whether the method works in human blood, and against other toxic chemicals, such as scorpion venom and anthrax, which use similar attack strategies
Mars Base

Wireless 'tooth tattoo' detects harmful bacteria - 0 views

phys.org/...ess-tooth-tattoo-bacteria.html

scibyte49 bacteria tooth health

shared by Mars Base on 30 May 12 - No Cached
  • Using silk strands pulled from cocoons and gold wires thinner than a spider's web, researchers at Princeton University have created a removable tattoo that adheres to dental enamel and could eventually monitor a patient's health with unprecedented sensitivity
Mars Base

2013 in science - Wikipedia, the free encyclopedia - 0 views

en.wikipedia.org/...2013_in_science

scibyte114 2013YearInReview

shared by Mars Base on 23 Dec 13 - No Cached
  • Morocco in 2011, and report that it is a new type of Mars rock with an unusually high water content.[8][9][10] American researchers state that a gene associated with active personality traits is also linked to
  • Astronomers affiliated with the Kepler space observatory announce the discovery of KOI-172.02, an Earth-like exoplanet candidate which orbits a star similar to the Sun in the habitable zone
  • 13 January – Massachusetts doctors invent a pill-sized medical scanner that can be safely swallowed by patients, allowing the esophagus to be more easily scanned for disease
  • ...101 more annotations...
  • 17 January – NASA announces that the Kepler space observatory has developed a reaction wheel issue
  • 2 January A study by Caltech astronomers reports that the Milky Way Galaxy contains at least one planet per sta
  • 3 January
  • 8 January
  • 20 January – Scientists prove that quadruple-helix DNA is present in human cells
  • 25 January
  • An international team of scientists develops a functional light-based "tractor beam", which allows individual cells to be selected and moved at will. The invention could have broad applications in medicine and microbiology
  • 30 January – South Korea conducts its first successful orbital launch
  • 6 February
  • Astronomers report that 6% of all dwarf stars – the most common stars in the known universe – may host Earthlike planets
  • Scientists discover live bacteria in the subglacial Antarctic Lake Whillans
  • American scientists finish drilling down to the subglacial Lake Whillans, which is buried around 1 kilometre (0.62 mi) under the Antarctic ice
  • 10 February NASA's Curiosity Mars rover uses its onboard drill to obtain the first deep rock sample ever retrieved from the surface of another plane
  • 15 February A 10-ton meteoroid impacts in Chelyabinsk, Russia, producing a powerful shockwave and injuring over 1,000 people
  • 28 February
  • Astronomers make the first direct observation of a protoplanet forming in a disk of gas and dust around a distant sta
  • A third radiation belt is discovered around the Eart
  • 1 March – Boston Dynamics demonstrates an updated version of its BigDog military robot
  • 3 March – American scientists report that they have cured HIV in an infant by giving the child a course of antiretroviral drugs very early in its life. The previously HIV-positive child has reportedly exhibited no HIV symptoms since its treatment, despite having no further medication for a year
  • researchers replace 75 percent of an injured patient's skull with a precision 3D-printed polymer replacement implant. In future, damaged bones may routinely be replaced with custom-manufactured implants
  • 7 March
  • A study concludes that heart disease was common among ancient mummies
  • 11 March
  • 12 March NASA's Curiosity rover finds evidence that conditions on Mars were once suitable for microbial life after analyzing the first drilled sample of Martian rock, "John Klein" rock at Yellowknife Bay in Gale Crater. The rover detected water, carbon dioxide, oxygen, sulfur dioxide, hydrogen sulfide, chloromethane and dichloromethane. Related tests found results consistent with the presence of smectite clay minerals
  • 14 March CERN scientists confirm, with a very high degree of certainty, that a new particle identified by the Large Hadron Collider in July 2012 is the long-sought Higgs boson
  • 18 March
  • NASA reports evidence from the Curiosity rover on Mars of mineral hydration, likely hydrated calcium sulfate, in several rock samples, including the broken fragments of "Tintina" rock and "Sutton Inlier" rock as well as in the veins and nodules in other rocks like "Knorr" rock and "Wernicke" rock.[177] Analysis using the rover's DAN instrument provided evidence of subsurface water, amounting to as much as 4% water content, down to a depth of 60 cm
  • 27 March – A potential new weight loss method is discovered, after a 20% weight reduction was achieved in mice simply by having their gut microbes altered.
  • NASA scientists report that hints of dark matter may have been detected by the Alpha Magnetic Spectrometer on the International Space Station
  • 3 April
  • 15 April A functional lab-grown kidney is successfully transplanted into a live rat in Massachusetts General Hospital
  • 18 April – NASA announces the discovery of three new Earthlike exoplanets – Kepler-62e, Kepler-62f, and Kepler-69c – in the habitable zones of their respective host stars, Kepler-62 and Kepler-69. The new exoplanets, which are considered prime candidates for possessing liquid water and thus potentially life, were identified using the Kepler spacecraft
  • 21 April The Antares rocket, a commercial launch vehicle developed by Orbital Sciences Corporation, successfully conducts its maiden flight
  • After years of unpowered glide tests, Scaled Composites' SpaceShipTwo hybrid spaceplane successfully conducts its first rocket-powered fligh
  • 29 April
  • 1 May IBM scientists release A Boy and His Atom, the smallest stop-motion animation ever created, made by manipulating individual carbon monoxide molecules with a scanning tunnelling microscope
  • A new study finds that children whose parents suck on their pacifiers have fewer allergies later in life
  • NASA reports that a reaction wheel on the Kepler space observatory may be malfunctioning and may result in the premature termination of the observatory's search for Earth-like
  • 15 May
  • 16 May Water dating back 2.6 billion years, by far the oldest ever found, is discovered in a Canadian mine
  • 27 May Four-hundred-year-old bryophyte specimens left behind by retreating glaciers in Canada are brought back to life in the laboratory
  • 29 May
  • Russian scientists announce the discovery of mammoth blood and well-preserved muscle tissue from an adult female specimen in Siberia
  • A new treatment to "reset" the immune system of multiple sclerosis patients is reported to reduce their reactivity to myelin by 50 to 75 percent
  • 4 June
  • During the Shenzhou 10 mission, Chinese astronauts deliver the country's first public video broadcast from the orbiting Tiangong-1 space laboratory
  • 20 June
  • China's Shenzhou 10 manned spacecraft returns safely to Earth, having conducted China's longest manned space mission to date
  • 26 June
  • 20 June
  • 20 June
  • 6 July
  • Scientists report that a wide variety of microbial life exists in the subglacial Antarctic Lake Vostok, which has been buried in ice for around 15 million years. Samples of the lake's water obtained by drilling were found to contain traces of DNA from over 3,000 tiny organisms
  • 15 July
  • ASA engineers successfully test a rocket engine with a fully 3D-printed injector
  • 19 July
  • NASA scientists publish the results of a new analysis of the atmosphere of Mars, reporting a lack of methane around the landing site of the Curiosity rover
  • Earth is photographed from the outer solar system. NASA's Cassini spacecraft releases images of the Earth and Moon taken from the orbit of Saturn
  • 29 July – Astronomers discover the first exoplanet orbiting a brown dwarf, 6,000 light years from Earth
  • exoplanet
  • 7 January
  • Astronomers
  • report that "at least 17 billion" Earth-sized exoplanets are estimated to reside in the Milky Way Galaxy
  • 20 February
  • NASA reports the discovery of Kepler-37b, the smallest exoplanet yet known, around the size of Earth's Moon
  • 10 June
  • Scientists report that the earlier claims of an Earth-like exoplanet orbiting Alpha Centauri B, a star close to our Solar System, may not be supported by astronomical evidence
  • 25 June – In an unprecedented discovery, astronomers detect three potentially Earthlike exoplanets orbiting a single star in the Gliese 667
  • 11 July For the first time, astronomers determine the true colour of a distant exoplanet. HD 189733 b, a searing-hot gas giant, is said to be a vivid blue colour, most likely due to clouds of silica in its atmosphere
  • NASA announces that the failing Kepler space observatory may never fully recover. New missions are being considered
  • 15 August
  • Phase I clinical trials of SAV001 – the first and only preventative HIV vaccine – have been successfully completed with no adverse effects in all patients. Antibody production was greatly boosted after vaccination
  • 3 September
  • 12 September NASA announces that Voyager I has officially left the Solar System, having travelled since 1977
  • NASA scientists report the Mars Curiosity rover detected "abundant, easily accessible" water (1.5 to 3 weight percent) in soil samples
  • 26 September
  • In addition, the rover found two principal soil types: a fine-grained mafic type and a locally derived, coarse-grained felsic type
  • mafic
  • as associated with hydration of the amorphous phases of the soi
  • perchlorates, the presence of which may make detection of life-related organic molecules difficult, were found at the Curiosity rover landing site
  • earlier at the more polar site of the Phoenix lander) suggesting a "global distribution of these salts
  • Astronomers have created the first cloud map of an exoplanet, Kepler-7b
  • 30 September
  • 8 October The Nobel Prize in Physics has been awarded to François Englert and Peter Higgs "for the theoretical discovery of a mechanism that contributes to our understanding of the origin of mass of subatomic particles, and which recently was confirmed through the discovery of the predicted fundamental particle, by the ATLAS and CMS experiments at CERN's Large Hadron Collider"
  • 16 October Russian authorities raise a large fragment, 654 kg (1,440 lb) total weight, of the Chelyabinsk meteor, a Near-Earth asteroid that entered Earth's atmosphere over Russia on 15 February 2013, from the bottom of Chebarkul lake.
  • Researchers have shown that a fundamental reason for sleep is to clean the brain of toxins. This is achieved by brain cells shrinking to create gaps between neurons, allowing fluid to wash through
  • 17 October
  • 22 October – Astronomers have discovered the 1,000th known exoplanet
  • 4 November - Astronomers report, based on Kepler space mission data, that there could be as many as 40 billion Earth-sized planets orbiting in the habitable zones of sun-like stars and red dwarf stars within the Milky Way Galaxy
  • 11 billion of these estimated planets may be orbiting sun-like stars
  • 5 November – India launches its first Mars probe, Mangalyaan
  • The IceCube Neutrino Observatory has made the first discovery of very high energy neutrinos on Earth which had originated from beyond our Solar System
  • 21 November
  • 1 December – China launches the Chang'e 3 lunar rover mission, with a planned landing on December 16
  • 3 December – The Hubble Space Telescope has found evidence of water in the atmospheres of five distant exoplanets: HD 209458b, XO-1b, WASP-12b, WASP-17b and WASP-19b
  • 9 December NASA scientists report that the planet Mars had a large freshwater lake (which could have been a hospitable environment for microbial life) based on evidence from the Curiosity rover studying Aeolis Palus near Mount Sharp in Gale Crater
  • 12 December NASA announces, based on studies with the Hubble Space Telescope, that water vapor plumes were detected on Europa, moon of Jupiter
  • 14 December – The unmanned Chinese lunar rover Chang'e 3 lands on the Moon, making China the third country to achieve a soft landing there
  • 18 December
  • nomers have spotted what appears to be the first known "exomoon", located 1,800 light years away
  • 20 December – NASA reports that the Curiosity rover has successfully upgraded, for the third time since landing, its software programs and is now operating with version 11. The new software is expected to provide the rover with better robotic arm and autonomous driving abilities. Due to wheel wear, a need to drive more carefully, over the rough terrain the rover is currently traveling on its way to Mount Sharp, was also reported
Mars Base

Lyme Disease Bacteria Found in 15-Million-Year-Old Amber | Paleontology | Sci-News.com - 0 views

www.sci-news.com/...ease-bacteria-amber-01956.html

scibyte133 LymeDidease

shared by Mars Base on 01 Jun 14 - No Cached
  • In 30 years of studying diseases revealed in the fossil record, the scientist has documented the ancient presence of such diseases as malaria, leishmania, and others.
  • Lyme disease
  • can cause problems with joints, the heart and central nervous system
  • ...1 more annotation...
  • This is the oldest fossil evidence of ticks associated with such bacteria.
Mars Base

NASA - NASA Researchers Discover Ancient Microbes in Antarctic Lake - 0 views

www.nasa.gov/...12-408_Lake_Vida_Microbes.html

scibyte73 AntarcticLake

shared by Mars Base on 01 Dec 12 - No Cached
  • In one of the most remote lakes of Antarctica, nearly 65 feet beneath the icy surface, scientists
  • , have uncovered a community of bacteria
  • one of Earth's darkest, saltiest and coldest habitats
  • ...16 more annotations...
  • increase our limited knowledge of how life can sustain itself in these extreme environments on our own planet and beyond.
  • Lake Vida, the largest of several unique lakes found in the McMurdo Dry Valleys, contains no oxygen, is mostly frozen and possesses the highest nitrous oxide levels of any natural water body on Earth
  • approximately six times saltier than seawater
  • average temperature is minus 8 degrees Fahrenheit
  • the brine harbors a surprisingly diverse and abundant variety of bacteria that survive without a current source of energy from the sun
  • Previous studies of Lake Vida dating back to 1996 indicate the brine and its inhabitants have been isolated from outside influences for more than 3,000 years.
  • the best analog we have for possible ecosystems in the subsurface waters of Saturn's moon Enceladus and Jupiter's moon Europa
  • collaborators
  • developed stringent protocols and specialized equipment for their 2005 and 2010 field campaigns to sample from the lake brine while avoiding contaminating the pristine ecosystem
  • expands our knowledge of environmental limits for life and helps define new niches of habitability
  • To sample unique environments such as this, researchers must work under secure, sterile tents on the lake's surface
  • The tents kept the site and equipment clean as researchers drilled ice cores, collected samples of the salty brine residing in the lake ice and assessed the chemical qualities of the water and its potential for harboring and sustaining life
  • analyses suggest chemical reactions between the brine and the underlying iron-rich sediments generate nitrous oxide and molecular hydrogen
  • may provide the energy needed to support the brine's diverse microbial life.
  • Additional research is under way to analyze the abiotic, chemical interactions between the Lake Vida brine and its sediment
  • investigating the microbial community by using different genome sequencing approaches
Mars Base

Hot-spring fossils preserve complete Jurassic ecosystem - 0 views

www.physorg.com/...ossils-jurassic-ecosystem.html

scibyte36 fossils

shared by Mars Base on 03 Mar 12 - No Cached
  • Scientists are uncovering a beautifully-preserved ecosystem from around a Jurassic hot spring, helping fill a gap in the fossil record of more than 300 million years.
  • Patagonia in southern Argentina, the San Agustin geothermal deposits include animals, plants, fungi and bacteria, preserved in three dimensions and with their internal structure largely intact.
  • date from around 150 million years ago
  • ...9 more annotations...
  • formed around an area where water heated deep underground rose to the surface
  • first time a hot-spring habitat from the Mesozoic era (from about 250 to 65 million years ago) has ever been discovered
  • Hot springs
  • are treasure troves for palaeontologists
  • the dissolved silica in their waters quickly penetrates and preserves the bodies of living things that die there
  • preserved in three dimensions rather than crushed into a two-dimensional film
  • It's a near-intact ecosystem that's beautifully preserved
  • We have the remains of everything from the bacteria living right around the hot spring vents all the way to the plants, crustaceans and insects living in wetlands further away and the trees and ferns from the forests around the margins. We also have evidence of how all these organisms interacted
  • The discovery of a rich assemblage of fossils from between these extremes could transform scientists' understanding of a vital stage in life's development
Mars Base

Mmmmm? Scientists Make Bread Last 60 Days | Popular Science - 0 views

www.popsci.com/...rves-sandwich-parts-two-months

scibyte73 FoodPreservation

shared by Mars Base on 04 Dec 12 - No Cached
  • Using microwave technology, one company says it can make bread last for two months, thus cutting down on food waste
  • spinoff company claims it can preserve at least some of our food for longer, by zapping it with microwaves
  • Nuked bread can last up to 60 days, according to the company
  • ...3 more annotations...
  • The equipment, which looks like a CT scanner for food, was originally developed to kill organisms like multi-resistant staph bacteria and salmonella
  • developers realized it also kills bread mold in about a 10-second zap. It works much like a home microwave, but the waves are produced in various frequencies, which allows for uniform heating
  • technology could also preserve fresh food like poultry, produce and more
Mars Base

A new way to lose weight? Study shows that changes to gut microbiota may play role in w... - 0 views

medicalxpress.com/...-gut-microbiota-role-loss.html

scibyte88 WeightLoss

shared by Mars Base on 28 Mar 13 - No Cached
  • by colonizing mice with the altered microbial community, the mice were able to maintain a lower body fat, and lose weight – about 20% as much as they would if they underwent surgery
  • New research
  • has found that the gut microbes of mice undergo drastic changes following gastric bypass surgery
  • ...28 more annotations...
  • In some ways we were biasing the results against weight loss
  • the mice used in the study hadn't been given a high-fat, high-sugar diet to increase their weight beforehand
  • The question is whether we might have seen a stronger effect if they were on a different diet
  • finding ways to manipulate microbial populations to mimic those effects could become a valuable new tool to address obesity
  • study suggests that the specific effects of gastric bypass on the microbiota contribute to its ability to cause weight loss
  • need to learn a good deal more about the mechanisms by which a microbial population changed by gastric bypass exert its effects,
  • then we need to learn if we can produce these effects – either the microbial changes or the associated metabolic changes – without surgery
  • it may be years before they could be replicated in humans, and that such microbial changes shouldn't be viewed as a way to lose
  • pounds without going to the gym
  • the technique may one day offer hope to dangerously obese people who want to lose weight without going through the trauma of surgery.
  • may not be that we will have a magic pill that will work for everyone who's slightly overweight
  • But if we can, at a minimum, provide some alternative to gastric bypass surgery that produces similar effects, it would be a major advance
  • While there had been hints that the microbes in the gut might change after bypass surgery, the speed and extent of the change came as a surprise to the research team
  • In earlier experiments, researchers had shown that the guts of both lean and obese mice are populated by varying amounts of two types of bacteria
  • When mice undergo gastric bypass surgery, however, it "resets the whole picture
  • those changes occurred within a week of the surgery, and weren't short-lived – the altered gut microbial community remained stable for months afterward
  • the results may hold out the hope for weight loss without surgery
  • future studies are needed to understand exactly what is behind the weight loss seen in mice
  • A major gap in our knowledge is the underlying mechanism linking microbes to weight loss
  • certain microbes
  • found at higher abundance after surgery,
  • think those are good targets for beginning to understand what's taking place
  • the answer may not be the specific types of microbes, but a by-product they excrete.
  • In addition to changes in the microbes found in the gut, researchers found changes in the concentration of certain short-chain fatty acids
  • Other studies
  • have suggested that those molecules may be critical in signaling to the host to speed up metabolism, or not to store excess calories as fat.
  • hope to continue to explore those questions
  • such studies will allow us to understand how host/microbial interactions in general can influence the outcome of a given diet
Mars Base

Reseachers develop holographic technique for bionic vision - 0 views

medicalxpress.com/...c-technique-bionic-vision.html

scibyte84 BionicEye

shared by Mars Base on 27 Feb 13 - No Cached
  • Researchers
  • are testing the power of holography to artificially stimulate cells in the eye, with hopes of developing a new strategy for bionic vision restoration
  • optogenetics
  • ...16 more annotations...
  • uses gene therapy to deliver light-sensitive proteins to damaged retinal nerve cells
  • The basic idea of optogenetics is to take a light-sensitive protein from another organism, typically from algae or bacteria, and insert it into a target cell, and that photosensitizes the cell
  • Intense pulses of light can activate nerve cells newly sensitized by this gene therapy approach
  • researchers around the world are still searching for the best way to deliver the light patterns so that the retina "sees" or responds in a nearly normal way
  • The plan is to someday develop a prosthetic headset or eyepiece that a person could wear to translate visual scenes into patterns of light that stimulate the genetically altered cells.
  • The key, they say, is to use a light stimulus that is intense, precise, and can trigger activity across a variety of cells all at once.
  • The researchers turned to holography after exploring other options, including laser deflectors and digital displays
  • Digital light displays can stimulate many nerve cells at once, "but they have low light intensity and very low light efficiency
  • The genetically repaired cells are less sensitive to light than normal healthy retinal cells, so they preferably need a bright light source like a laser to be activated
  • Lasers give intensity, but they can't give the parallel projection
  • needed to see a complete picture
  • researchers have tested the potential of holographic stimulation in retinal cells in the lab
  • done some preliminary work with the technology in living mice with damaged retinal cells
  • The experiments show that holography can provide reliable and simultaneous stimulation of multiple cells at millisecond speeds.
  • implementing a holographic prosthesis in humans is far in the future
  • holography itself "also provides a very interesting path toward three-dimensional stimulation
Mars Base

Contest Challenges Students to Design Next Mars Rover | University Rover Challenge | Sp... - 0 views

www.space.com/niversity-rover-challenge.html

scibyte96 MarsSociety

shared by Mars Base on 28 May 13 - No Cached
  • The competition is hosted by the Mars Society, a non-profit research organization dedicated to promoting the exploration and eventual settlement of Mars
  • The competition site is located at the society's Mars Desert Research Station (MDRS), a rocky barren landscape that's about as close to Martian terrain as you can get on Earth
  • Each team was allowed to spend up to $15,000 on their rovers, which can weigh no more than 50 kilograms — about 110 lbs.
  • ...9 more annotations...
  • vehicles
  • compete in four challenges, designed to replicate the activities of NASA's rovers on Mars.
  • teams will guide their rovers to collect the subsurface soil samples most likely to contain photosynthetic bacteria, lichen and other bits of living material
  • specific tasks change each year, but the most difficult ones continue to be those that need rovers to do humanlike work
  • team members must guide their rovers via a remote connection, such as a computer in the back of a truck, as long as it's shielded so the team can't see their rovers
  • The URC is based on the assumption that the rovers are telerobots, which means they would be operated by astronauts on or orbiting Mars
  • In addition to collecting soil, the rovers will deliver a series of packages, such as emergency supplies to "astronauts" (URC staff) in the field, fix a dust-covered solar panel (without water, of course) and finally, navigate an obstacle course that will include climbing steep grades, getting over boulders and passing through PVC pipe gates, aimed to test each rover's maneuverability.
  • This year's teams represent universities and colleges in Canada, India, Poland and the United States
  • including two-time returning champions Toronto's York University (2012 and 2009) and Oregon State (2010 and 2008).
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