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Printable 'bionic' ear melds electronics and biology - 0 views

  • Scientists at Princeton University used off-the-shelf printing tools to create a functional ear that can "hear" radio frequencies far beyond the range of normal human capability
  • primary purpose was to explore an efficient and versatile means to merge electronics with tissue
  • used 3D printing of cells and nanoparticles followed by cell culture to combine a small coil antenna with cartilage, creating what they term a bionic ear.
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  • Previously, researchers have suggested some strategies
  • That typically happens between a 2D sheet of electronics and a surface of the tissue
  • our work suggests a new approach—to build and grow the biology up with the electronics synergistically and in a 3D interwoven format
  • Last year, a research effort
  • resulted in the development of a "tattoo" made up of a biological sensor and antenna that can be affixed to the surface of a tooth
  • This project, however, is the team's first effort to create a fully functional organ: one that not only replicates a human ability, but extends it using embedded electronics
  • Creating organs using 3D printers is a recent advance; several groups have reported using the technology for this purpose in the past few months
  • this is the first time that researchers have demonstrated that 3D printing is a convenient strategy to interweave tissue with electronics
  • Ear reconstruction "remains one of the most difficult problems in the field of plastic and reconstructive surgery
  • the team turned to a manufacturing approach called 3D printing
  • The finished ear consists of a coiled antenna inside a cartilage structure
  • Two wires lead from the base of the ear and wind around a helical "cochlea" – the part of the ear that senses sound – which can connect to electrodes
  • further work and extensive testing would need to be done before the technology could be used on a patient
  • the ear in principle could be used to restore or enhance human hearing.
  • electrical signals produced by the ear could be connected to a patient's nerve endings, similar to a hearing aid
  • The current system receives radio waves, but he said the research team plans to incorporate other materials, such as pressure-sensitive electronic sensors, to enable the ear to register acoustic sounds
  • researchers used an ordinary 3D printer to combine a matrix of hydrogel and calf cells with silver nanoparticles that form an antenna. The calf cells later develop into cartilage
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ScienceShot: There's Cow in Your Smog - ScienceNOW - 0 views

  • people typically blame Southern California's smog on automobiles, a new study suggests that cows may be just as responsible, if not more so
  • large fraction of the region's smog, especially the particles smaller than 2.5 micrometers in diameter, is ammonium nitrate
  • particles form in the atmosphere when ammonia, which is generated by cars with certain types of catalytic converters and by bacteria that consume cattle waste, reacts with nitrogen oxides that are produced in large quantities in automobile emissions
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  • Data gathered during low-altitude flights in and around the Los Angeles basin in May 2010 suggest that the region's 9.9 million autos generate about 62 metric tons of ammonia each day
  • ammonia emissions from dairy farms in the eastern portion of the basin—home to about 298,000 cattle—range between 33 and 176 metric tons per day
  • Ammonia emissions from the dairy farms are concentrated, boosting atmospheric levels of the gas to more than 100 times background levels, so efforts to curb the farms' emissions (perhaps by feeding the animals different diets) might reduce smog more than those targeting cars.
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Researchers find evidence of photosynthesis-like process in aphids - 0 views

  • In plants, algae and some types of bacteria and fungi, sunlight is converted to chemical energy in a process we all know as photosynthesis
  • water and carbon dioxide are also converted to oxygen
  • Now it appears that a type of aphid, a small insect, is able to do something similar, minus the water and carbon dioxide conversion
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  • Researchers at the Sophia Agrobiotech Institute in France, have found that not only do aphids produce carotenoids, but the amount they produce seems to be directly influenced by the amount of sunshine they receive in their daily life
  • Carotenoids are pigments that in most animals are obtained via consumption of other organisms that create it via photosynthesis
  • Aphids
  • are able to synthesize them all by themselves, making them stand out
  • Researchers aren’t sure why they do so, but many other animals rely on carotenoids to help bolster a strong immunity system
  • carotenoids in aphids are responsible for their color
  • high levels are green, those with very low levels are white, and those in-between are orange.
  • In this new research the team found that the levels of carotenoids in the aphids appeared to correlate with levels of adenosine triphosphate (ATP),
  • the way to measure the transfer of energy in living things
  • higher the level of carotenoids were the more ATP was present
  • when the team moved orange aphids in and out of direct sunlight, levels of carotenoids and ATP rose and sunk
  • suggesting the insect was getting energy directly through such exposure
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Why Do We Sneeze? - 0 views

  • When we breathe in foreign particles, sensors in our noses and sinuses detect the objects. The sensors signal the cilia—tiny, hairlike paddles that line our nostrils and sinuses—to move to expel the irritants
  • burst of air produced by a sneeze not only clears nasal passages but also triggers the cilia sensors to kick the paddles into high gear for an extended period
  • sneeze works by "resetting the system—like Control-Alt-Delete" on a PC
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  • Cilia—which resemble a "constantly moving shag carpet" under the microscope—propel potentially harmful material out of our lungs and either up to our nostrils to be expelled or down to our gullets, where stomach acid zaps any harmful organisms
  • People with sinusitis and genetic disorders such as cystic fibrosis have trouble clearing out mucus, even though they sneeze a lot.
  • For cilia to work, they need mucus
  • contradiction
  • wonder whether sneezing has a role in getting cilia to clear out mucus—and whether that process was somehow impaired in sinusitis patients
  • puffed air on the lining—a sort of "in vitro sneeze
  • If you puff air on these cells, [their cilia] beat faster
  • from sinusitis patients
  • , the cilia did not beat faster
  • patients aren't getting the same cellular response as patients who don't have the syndrome
  • chronic inflammation or toxins in sinusitis-related bacteria may be preventing the cilia from working properly
  • Can we actually take this information and translate it into a novel therapy
  • scientists could theoretically develop nasal sprays or other topical treatments to get the cilia revved up in people with impaired mucus clearance
  • no "satisfactory treatment option" for chronic sinusitis, which affects an estimated 14 to 16 million Americans
  • usually treated with medicine and surgery to relieve the symptoms, which can include congestion, reduced smell and taste, and pain or swelling in the face
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Researchers find evidence of link between immune irregularities and autism - 0 views

  • new Caltech study suggests that specific changes in an overactive immune system can contribute to autism-like behaviors in mice
  • remained unanswered
  • whether the immune changes play a causative role in the development of the disease or are merely a side effect
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  • new Caltech study suggests that specific changes in an overactive immune system can indeed contribute to autism-like behaviors in mice
  • have long suspected that the immune system plays a role in the development of autism spectrum disorder
  • Several large epidemiological studies—including one that involved tracking the medical history of every person born in Denmark between 1980 and 2005—have found a correlation between viral infection during the first trimester of a mother's pregnancy and a higher risk for autism spectrum disorder in her child
  • researchers characterized the immune system of the offspring of mothers that had been infected and found that the offspring display a number of immune changes
  • Some of those changes parallel those seen in people with autism,
  • alterations add up to an immune system in overdrive—one that promotes inflammation
  • researchers were able to correct many of the autism-like behaviors in the offspring of immune-activated mothers by giving the offspring a bone-marrow transplant from typical mice
  • because the work was conducted in mice, the results cannot be readily extrapolated to humans
  • bone-marrow transplants should be considered as a treatment for autism
  • In future studies, the researchers plan to examine the effects of highly targeted anti-inflammatory treatments on mice that display autism-related behaviors and immune changes
  • also interested in considering the gastrointestinal (GI) bacteria
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Storm Scents: It's True, You Can Smell Oncoming Summer Rain: Scientific American - 0 views

  • When people say they can smell a storm coming, they're right
  • Weather patterns produce distinctive odors that sensitive noses sniff out.
  • Before the rain begins, one of the first odors you may notice
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  • is a sweet, pungent zing in your nostrils
  • fresh aroma of ozone
  • Petrichor
  • occurs when airborne molecules from decomposing plant or animal matter become attached to mineral or clay surfaces
  • when the rains came, the redolent combination of fatty acids, alcohols and hydrocarbons is released
  • Petrichor potpourri
  • Falling water disturbs and displaces odoriferous molecules on surfaces, particularly on dry ones, and carry them into the
  • happen to be near vegetation, these molecules may come from plants and trees
  • rise up from concrete and asphalt
  • Damp earth
  • After a storm has moved through
  • aroma of geosmin, a metabolic by-product of bacteria or blue-green algae
  • Microbiologist Keith Chater at the John Innes Center in England has proposed that geosmin's fragrance may be a beacon, helping camels find their way to desert oases
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New class of antibiotics discovered by chemists -- ScienceDaily - 0 views

  • team of
  • researchers
  • have discovered a new class of antibiotics to fight
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  • drug-resistant bacteria
  • oxadiazoles, was discovered in silico (by computer) screening
  • has shown promise in the treatment of MRSA in mouse models of infection
  • Researchers
  • screened 1.2 million compounds found that the oxadiazole inhibits a penicillin-binding protein,
  • The oxadiazoles are also effective when taken orally
  • there is only one marketed antibiotic for MRSA that can be taken orally.
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Back to life after 1,500 years: Moss brought back to life after 1,500 years frozen in i... - 0 views

  • Researchers from the British Antarctic Survey and Reading University have demonstrated that, after over 1,500 years frozen in Antarctic ice, moss can come back to life and continue to grow
  • The team,
  • observed moss regeneration after at least 1,530 years frozen in permafrost
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  • This is the first study to show such long-term survival in any plant; similar timescales have only been seen before in bacteria
  • Mosses are
  • the dominant plants over large areas and are a major storer of fixed carbon
  • The team took cores of moss from deep in a frozen moss bank in the Antarctic
  • This moss would already have been at least decades old when it was first frozen
  • in an incubator at a normal growth temperature and light level
  • After only a few weeks,
  • the moss began to grow
  • Using carbon dating, the team identified the moss to be at least 1,530 years of age, and possibly even older, at the depth where the new growth was seen.
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May 26 - Today in Science History - Scientists born on May 26th, died, and events - 0 views

  • Leeuwenhoek's animalcules
  • In 1676, Antonie van Leeuwenhoek applied his hobby of making microscopes from his own handmade lenses to observe some water running off a roof during a heavy rainstorm. He finds that it contains, in his words, “very little animalcules.” The life he has found in the runoff water is not present in pure rainwater. This was a fundamental discovery, for it showed that the bacteria and one-celled animals did not fall from the sky. When a ball of molten glass is inflated like a balloon, a small droplet of the hot fluid collects at the very bottom the bubble. Leeuwenhoek used these droplets as microscope lenses to view the animalcules. Despite their crude nature, those early lenses enabled Leeuwenhoek to describe an amazing world of microscopic life
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