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Ministry of Supply: 2012 America's Coolest College Start-ups | Inc.com - 0 views

  • Ministry of Supply’s “agent shirt” and undershirts are made of moisture-wicking fabrics with antibacterial coatings and are wrinkle-free
Mars Base

Bacteria-eating viruses 'magic bullets in the war on superbugs' - 0 views

  • A specialist team of scientists from the University of Leicester has isolated viruses that eat bacteria -- called phages -- to specifically target the highly infectious hospital superbug Clostridium difficile
  • predominantly been funded by the Medical Research Council (MRC).
  • been investigating an alternative approach to antibiotics, which utilizes naturally occurring viruses called bacteriophages, meaning 'eaters of bacteria'.
  • ...24 more annotations...
  • since the discovery of the first antibiotic, penicillin, antibiotics
  • have saved countless lives and impacted on the well-being of humanity
  • the future impact of antibiotics is dwindling
  • with more and more bacteria
  • 'out-evolving' these miracle drugs
  • bacteriophages
  • are specific in what they kill and will generally only infect one particular species, or even strain, of bacteria
  • Following attachment to their hosts, they inject their DNA into the bacterium, which then replicates many times over, ultimately causing the bacterial cell to burst open
  • team have
  • , a specific mixture of phages have been proved, through extensive laboratory testing, to be effective against 90% of the most clinically relevant C. diff strains currently seen in the U.K
  • US-based biopharmaceutical company and pioneers in developing phage-based therapeutics
  • have already made progress in developing phages targeted against Pseudomonas aeruginosa, a pathogen that causes acute, life-threatening lung infections in cystic fibrosis patients
  • funding further development and testing
  • phages developed
  • is to have a phage mixture ready to go into phase 1 and 2 clinical trials
  • Evaluations of the efficacy of bacteriophage therapy and optimisation of dosing regimes will be carried out
  • bacteria primarily affect our digestive system
  • pose a serious threat when our natural digestive environment is disrupted or depleted, such as after chronic antibiotic use
  • antibiotics also destroy the 'good' gut bacteria, in turn increasing the potential for relapse or new infections
  • The key advantage of using phages over antibiotics
  • A phage will infect and kill only a specific strain/species of bacteria.
  • Antibacterial resistance is a major and growing threat to health globally
  • This study
  • examines a new way to kill bacteria to circumvent resistance formation
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