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thinkahol *

First successful transplantation of a synthetic windpipe | KurzweilAI - 0 views

www.kurzweilai.net/tation-of-a-synthetic-windpipe

First successful transplantation of a synthetic windpipe | KurzweilAI

shared by thinkahol * on 16 Jul 11 - No Cached
  • thinkahol * on 16 Jul 11
     
    A 36-year-old man has received the world's first synthetic trachea, made from a synthetic scaffold seeded with his own stem cells, in an operation at the Karolinska University Hospital in Stockholm, Sweden. Professor Paolo Macchiarini of Karolinska University Hospital and Karolinska Institutet led an international team, including professor Alexander Seifalian from University College London, who designed and built the nanocomposite tracheal scaffold, and Harvard Bioscience, which produced a specifically designed bioreactor used to seed the scaffold with the patient´s own stem cells. The cells were grown on the scaffold inside the bioreactor for two days before transplantation to the patient. Because the cells used to regenerate the trachea were the patient's own, there has been no rejection of the transplant and the patient is not taking immunosuppressive drugs. "The big conceptual breakthrough is that we can move from transplanting organs to manufacturing them for patients," says David Green, the president of Harvard Bioscience in Holliston, Massachusetts. Transplantations of tissue-engineered windpipes with synthetic scaffolds in combination with the patient's own stem cells as a standard procedure means that patients will not have to wait for a suitable donor organ. Patients could benefit from earlier surgery and have a greater chance of cure. This would be of especially great value for children, since the availability of donor tracheas is much lower than for adult patients.
Todd Suomela

Amateur Science and the Rise of Big Science | Citizen Scientists League - 0 views

citizenscientistsleague.com/...ce-and-the-rise-of-big-science

science amateur professional success citizen-science history government funding sts

shared by Todd Suomela on 04 Apr 13 - No Cached
  • Several trends came together to increase the professional nature of scientific work. First was the increasing cost of scientific work and its complexity. Scientific equipment became more precise and expensive. Telescopes, like those by Herschel, became bigger and bigger. Also, the amount of knowledge one needed to gain to contribute became increasingly daunting.
  • Second, the universities changed. Pioneered by the German states, which at the beginning of the 19th century was dismissed as a scientific backwater, universities began offering focused majors which trained students in a specific discipline rather than classical education as a whole. This was pioneered by Wilhelm von Humboldt, brother of the famous scientist Alexander von Humboldt, who was the Prussian Minister of Education.
  • Germany, once united, also provided impetus to two other trends that accelerated their dominance of science and the decline of amateurs. First, was the beginning of large-scale state sponsorship of science through grants which were first facilitated through the Kaiser Wilhelm Institute (now the Max Planck Institute). This eventually supplanted prizes as the dominant large-scale source of scientific funding. Countries like France that relied on prizes began to fall behind. Second, was the intimate cooperation between industrial firms like BASF and universities.
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  • he final nail in the coffin was undoubtedly the Second World War. The massive mobilization of scientific resources needed to win and the discovery of war-winning inventions such as the atomic bomb and self-correcting bomb sight (with help from Norbert Wiener of MIT) convinced the nations of the world that the future was in large-scale funding and support of science as a continuous effort. Vannevar Bush, former president of MIT, and others pioneered the National Science Foundation and the military also invested heavily in its own research centers. Industrial labs such as those from Bell Labs, GE, Kodak, and others began dominating research as well. Interestingly, the first military investment in semiconductors coupled with research from Bell Labs led to what is now known as Silicon Valley.
Todd Suomela

The Technium: The World Without Technology - 0 views

www.kk.org/...the_world_witho.php

technology technology-effects history anthropology language evolution culture archaeology

shared by Todd Suomela on 10 Apr 09 - Cached
  • Although strictly speaking simple tools are a type of technology made by one person, we tend to think of technology as something much more complicated. But in fact technology is anything designed by a mind. Technology includes not only nuclear reactors and genetically modified crops, but also bows and arrows, hide tanning techniques, fire starters, and domesticated crops. Technology also includes intangible inventions such as calendars, mathematics, software, law, and writing, as these too derive from our heads. But technology also must include birds' nests and beaver dams since these too are the work of brains. All technology, both the chimp's termite fishing spear and the human's fishing spear, the beaver's dam and the human's dam, the warbler's hanging basket and the human's hanging basket, the leafcutter ant's garden and the human's garden, are all fundamentally natural. We tend to isolate human-made technology from nature, even to the point of thinking of it as anti-nature, only because it has grown to rival the impact and power of its home. But in its origins and fundamentals a tool is as natural as our life.
  • The gravity of technology holds us where we are. We accept our attachment. But to really appreciate the effects of technology – both its virtues and costs -- we need to examine the world of humans before technology. What were our lives like without inventions? For that we need to peek back into the Paleolithic era when technology was scarce and humans lived primarily surrounded by things they did not make. We can also examine the remaining contemporary hunter-gatherer tribes still living close to nature to measure what, if anything, they gain from the small amount of technology they use.
  • Then about 50,000 years ago something amazing happened. While the bodies of early humans in Africa remained unchanged, their genes and minds shifted noticeably. For the first time hominins were full of ideas and innovation. These newly vitalized modern humans, which we now call Sapiens, charged into new regions beyond their ancestral homes in eastern Africa. They fanned out from the grasslands and in a relatively brief burst exploded from a few tens of thousands in Africa to an estimated 8 million worldwide just before the dawn of agriculture 10,000 years ago.
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  • It should have been clear to Neanderthal, as it is now clear to us in the 21st century, that something new and big had appeared -- a new biological and geological force. A number of scientists (Richard Klein, Ian Tattersall, William Calvin, among many others) think that the "something" that happened 50,000 years ago was the invention of language. Up until this point, humanoids were smart. They could make crude tools in a hit or miss way and handle fire – perhaps like an exceedingly smart chimp. The African hominin's growing brain size and physical stature had leveled off its increase, but evolution continued inside the brain.  "What happened 50,000 years ago," says Klein, "was a change in the operating system of humans. Perhaps a point mutation effected the way the brain is wired that allowed languages, as we understand language today: rapidly produced, articulate speech."  Instead of acquiring a larger brain, as the Neanderthal and Erectus did, Sapien gained a rewired brain.  Language altered the Neanderthal-type mind, and allowed Sapien minds for the first time to invent with purpose and deliberation. Philosopher Daniel Dennet crows in elegant language: "There is no step more uplifting, more momentous in the history of mind design, than the invention of language. When Homo sapiens became the beneficiary of this invention, the species stepped into a slingshot that has launched it far beyond all other earthly species." The creation of language was the first singularity for humans. It changed everything. Life after language was unimaginable to those on the far side before it.
thinkahol *

5 Things That Internet Porn Reveals About Our Brains | Sex & the Brain | DISCOVER Magazine - 0 views

discovermagazine.com/...article_view

5 Things That Internet Porn Reveals About Our Brains | Sex & the Brain DISCOVER Magazine

shared by thinkahol * on 21 Sep 11 - No Cached
  • thinkahol * on 21 Sep 11
     
    With its expansive range and unprecedented potential for anonymity, (the Internet gives voice to our deepest urges and most uninhibited thoughts. Inspired by the wealth of unfettered expression available online, neuroscientists Ogi Ogas and Sai Gaddam, who met as Ph.D. candidates at Boston University, began plumbing a few chosen search engines (including Dogpile and AOL) to create the world's largest experiment in sexuality in 2009. Quietly tapping into a billion Web searches, they explored the private activities of more than 100 million men and women around the world. The result is the first large-scale scientific examination of human sexuality in more than half a century, since biologist Alfred Kinsey famously interviewed more than 18,000 middle-class Caucasians about their sexual behavior and published the Kinsey reports in 1948 and 1953. Building on the work of Kinsey, neuroscientists have long made the case that male and female sexuality exist on different planes. But like Kinsey himself, they have been hampered by the dubious reliability of self-reports of sexual behavior and preferences as well as by small sample sizes. That is where the Internet comes in. By accessing raw data from Web searches and employing the help of Alexa-a company that measures Web traffic and publishes a list of the million most popular sites in the world-Ogas and Gaddam shine a light on hidden desire, a quirky realm of lust, fetish, and kink that, like the far side of the moon, has barely been glimpsed. Here is a sampling of their fascinating results, selected from their book, A Billion Wicked Thoughts.
Todd Suomela

Thatcher, Scientist - 0 views

rsnr.royalsocietypublishing.org/...215

politics science experience biography country(GreatBritain) 20c sts history

shared by Todd Suomela on 28 Feb 12 - No Cached
  • Todd Suomela on 28 Feb 12
     
    This paper has two halves. First, I piece together what we know about Margaret Thatcher's training and employment as a scientist. She took science subjects at school; she studied chemistry at Oxford, arriving during World War II and coming under the influence (and comment) of two excellent women scientists, Janet Vaughan and Dorothy Hodgkin. She did a fourth-year dissertation on X-ray crystallography of gramicidin just after the war. She then gathered four years' experience as a working industrial chemist, at British Xylonite Plastics and at Lyons. Second, my argument is that, having lived the life of a working research scientist, she had a quite different view of science from that of any other minister responsible for science. This is crucial in understanding her reaction to the proposals-associated with the Rothschild reforms of the early 1970s-to reinterpret aspects of science policy in market terms. Although she was strongly pressured by bodies such as the Royal Society to reaffirm the established place of science as a different kind of entity-one, at least at core, that was unsuitable to marketization-Thatcher took a different line.
Todd Suomela

Rationally Speaking: The very foundations of science - 0 views

rationallyspeaking.blogspot.com/...ry-foundations-of-science.html

sts philosophy induction about(DavidHume) science probability

shared by Todd Suomela on 08 Mar 09 - Cached
  • The first way to think about probability is as a measure of the frequency of an event: if I say that the probability of a coin to land heads up is 50% I may mean that, if I flip the coin say 100 times, on average I will get heads 50 times. This is not going to get us out of Hume’s problem, because probabilities interpreted as frequencies of events are, again, a form of induction
  • Secondly, we can think of probabilities as reflecting subjective judgment. If I say that it is probable that the coin will land heads up, I might simply be trying to express my feeling that this will be the case. You might have a different feeling, and respond that you don’t think it's probable that the coin will lend heads up. This is certainly not a viable solution to the problem of induction, because subjective probabilities are, well, subjective, and hence reflect opinions, not degrees of truth.
  • Lastly, one can adopt what Okasha calls the logical interpretation of probabilities, according to which there is a probability X that an event will occur means that we have objective reasons to believe (or not) that X will occur (for instance, because we understand the physics of the solar system, the mechanics of cars, or the physics of coin flipping). This doesn’t mean that we will always be correct, but it does offer a promising way out of Hume’s dilemma, since it seems to ground our judgments on a more solid foundation. Indeed, this is the option adopted by many philosophers, and would be the one probably preferred by scientists, if they ever gave this sort of thing a moment’s thought.
  • Todd Suomela on 08 Mar 09
     
    short summary of some probabilistic responses to the problem of induction
Todd Suomela

Human Computer Interaction (HCI) by John M. Carroll - Interaction-Design.org: HCI, Usab... - 0 views

www.interaction-design.org/..._computer_interaction_hci.html

hci history technology science computer sts

shared by Todd Suomela on 07 Apr 09 - Cached
  • The challenge of personal computing became manifest at an opportune time. The broad project of cognitive science, which incorporated cognitive psychology, artificial intelligence, linguistics, cognitive anthropology, and the philosophy of mind, had formed at the end of the 1970s. Part of the programme of cognitive science was to articulate systematic and scientifically-informed applications to be known as "cognitive engineering". Thus, at just the point when personal computing presented the practical need for HCI, cognitive science presented people, concepts, skills, and a vision for addressing such needs. HCI was one of the first examples of cognitive engineering. Other historically fortuitous developments contributed to establishment of HCI. Software engineering, mired in unmanageable software complexity in the 1970s, was starting to focus on nonfunctional requirements, including usability and maintainability, and on non-linear software development processes that relied heavily on testing. Computer graphics and information retrieval had emerged in the 1970s, and rapidly came to recognize that interactive systems were the key to progressing beyond early achievements. All these threads of development in computer science pointed to the same conclusion: The way forward for computing entailed understanding and better empowering users.
  • One of the most significant achievements of HCI is its evolving model of the integration of science and practice. Initially this model was articulated as a reciprocal relation between cognitive science and cognitive engineering. Later, it ambitiously incorporated a diverse science foundation, notably Activity Theory, distributed cognition, and ethnomethodology, and a culturally embedded conception of human activity, including the activities of design and technology development. Currently, the model is incorporating design practices and research across a broad spectrum. In these developments, HCI provides a blueprint for a mutual relation between science and practice that is unprecedented.
  • In the latter 1980s and early 1990s, HCI assimilated ideas from Activity Theory, distributed cognition, and ethnomethodology. This comprised a fundamental epistemological realignment. For example, the representational theory of mind, a cornerstone of cognitive science, is no longer axiomatic for HCI science. Information processing psychology and laboratory user studies, once the kernel of HCI research, became important, but niche areas. The most canonical theory-base in HCI now is socio-cultural, Activity Theory. Field studies became typical, and eventually dominant as an empirical paradigm. Collaborative interactions, that is, groups of people working together through and around computer systems (in contrast to the early 1980s user-at-PC situation) have become the default unit of analysis. It is remarkable that such fundamental realignments were so easily assimilated by the HCI community.
thinkahol *

Study shows that one 'super-corporation' pulls the strings of the global economy | Mail... - 0 views

www.dailymail.co.uk/...ls-strings-global-economy.html

Study shows that one 'super-corporation' pulls the strings of global economy | Mail Online

shared by thinkahol * on 20 Oct 11 - No Cached
  • thinkahol * on 20 Oct 11
     
    A University of Zurich study 'proves' that a small group of companies - mainly banks - wields huge power over the global economy. The study is the first to look at all 43,060 transnational corporations and the web of ownership between them - and created a 'map' of 1,318 companies at the heart of the global economy. The study found that 147 companies formed a 'super entity' within this, controlling 40 per cent of its  wealth. All own part or all of one another. Most are banks - the top 20 includes Barclays and Goldman Sachs. But the close connections mean that the network could be vulnerable to collapse
Infogreen Global

Antihydrogen Atoms Stored for the First Time - 0 views

infogreenglobal.com/toms-stored-for-the-first-time

antihydrogen antimatter anti-atoms magnetic-field octupole superconducting-magnet

shared by Infogreen Global on 19 Nov 10 - No Cached
  • Infogreen Global on 19 Nov 10
     
    Large quantities of antihydrogen atoms were first made at CERN eight years ago by two other teams. Although they made antimatter they couldn't store it, because the anti-atoms touched the ordinary-matter walls of the experiments within millionths of a second after forming and were instantly annihilated-completely destroyed by conversion to energy and other particles.
Todd Suomela

Guest Post: Tom Levenson on Isaac Newton as the First Cosmologist | Cosmic Variance - 0 views

cosmicvariance.com/...ewton-as-the-first-cosmologist

sts science history physics astronomy astrophysics

shared by Todd Suomela on 25 Jan 09 - Cached
  • Newton knew what he had done. He was no accidental writer. A parabola, of course, is a curve that keeps on going – and that meant that at the end of a very long and very dense book, he lifted off again from the hard ground of daily reality and said, in effect, look: All this math and all these physical ideas govern everything we can see, out to and past the point where we can’t see anymore. Most important, he did so with implacable rigor, a demonstration that, he argued, should leave no room for dissent. He wrote “The theory that corresponds exactly to so nonuniform a motion through the greatest part of the heavens, and that observes the same laws as the theory of the planets and that agrees exactly with exact astronomical observations cannot fail to be true.” (Italics added).
  • To make his ambitions absolutely clear Newton used the same phrase for the title of book three. There his readers would discover “The System of the World.” This is where the literary structure of the work really comes into play, in my view. Through book three, Newton takes his audience through a carefully constructed tour of all the places within the grasp of his new physics. It begins with an analysis of the moons of Jupiter, demonstrating that inverse square relationships govern those motions. He went on, to show how the interaction between Jupiter and Saturn would pull each out of a perfect elliptical orbit; the real world, he says here, is messier than a geometer’s dream.
thinkahol *

Historic first images of rod photoreceptors in the living human eye - 0 views

www.sciencedaily.com/...110608123010.htm

Historic first images of rod photoreceptors in the living human eye

shared by thinkahol * on 13 Jun 11 - No Cached
  • thinkahol * on 13 Jun 11
     
    ScienceDaily (June 9, 2011) - Scientists have just reported that the tiny light-sensing cells known as rods have been clearly and directly imaged in the living eye for the first time. Using adaptive optics (AO), the same technology astronomers use to study distant stars and galaxies, scientists can see through the murky distortion of the outer eye, revealing the eye's cellular structure with unprecedented detail. This innovation, described in two papers in the Optical Society's (OSA) open access journal Biomedical Optics Express, will help doctors diagnose degenerative eye disorders sooner, leading to quicker intervention and more effective treatments.
thinkahol *

First Quantum Effects Seen in Visible Object - 0 views

io9.com/#!5497720/first-quantum-effects-seen-in-visible-object

First Quantum Effects Seen in Visible Object

shared by thinkahol * on 08 Mar 11 - No Cached
  • thinkahol * on 08 Mar 11
     
    Aaron O'Connell and colleagues at the University of California, Santa Barbara, did not actually produce a cat that was dead and alive at the same time, as Erwin Schrödinger proposed in a notorious thought experiment 75 years ago. But they did show that a tiny resonating strip of metal - only 60 micrometres long, but big enough to be seen without a microscope - can both oscillate and not oscillate at the same time. Alas, you couldn't actually see the effect happening, because that very act of observation would take it out of superposition.
thinkahol *

Carl Sagan Day | Center for Inquiry - 2 views

centerforinquiry.net/carlsaganday

Carl Sagan Day | Center for Inquiry

shared by thinkahol * on 09 Nov 11 - No Cached
  • thinkahol * on 09 Nov 11
     
    Please join us this November as we honor Carl Sagan and celebrate the beauty and wonder of the cosmos he so eloquently described. Carl Sagan was a Professor of Astronomy and Space Science and Director of the Laboratory for Planetary Studies at Cornell University, but most of us know him as a Pulitzer Prize winning author and the creator of COSMOS. That Emmy and Peabody award-winning PBS television series transformed educational television when it first aired in 1980, but now, thirty years later, it's gone on to affect the hearts and minds of over a billion people in sixty countries. No other scientist has been able to reach and teach so many nonscientists in such a meaningful way, and that is why we celebrate Dr. Sagan, remember his work, and revel in the cosmos he helped us understand.
thinkahol *

Scientists report first solar cell producing more electrons in photocurrent than solar ... - 0 views

www.physorg.com/...ll-electrons-photocurrent.html

Scientists report first solar cell producing more electrons in photocurrent than photons entering

shared by thinkahol * on 16 Dec 11 - No Cached
  • thinkahol * on 16 Dec 11
     
    (PhysOrg.com) -- Researchers from the National Renewable Energy Laboratory (NREL) have reported the first solar cell that produces a photocurrent that has an external quantum efficiency greater than 100 percent when photoexcited with photons from the high energy region of the solar spectrum
thinkahol *

First Potentially Habitable Exoplanet found | KurzweilAI - 0 views

www.kurzweilai.net/ally-habitable-exoplanet-found

First Potentially Habitable Exoplanet found | KurzweilAI

shared by thinkahol * on 03 Oct 10 - No Cached
  • thinkahol * on 03 Oct 10
     
    A team of planet hunters from the University of California (UC) Santa Cruz and the Carnegie Institution has announced the discovery of a planet, Gliese 581g,
thinkahol *

Stressed-DNA repair protein identified | KurzweilAI - 0 views

www.kurzweilai.net/-dna-repair-protein-identified

Stressed-DNA repair protein identified | KurzweilAI

shared by thinkahol * on 21 Jun 11 - No Cached
  • thinkahol * on 21 Jun 11
     
    Vera Gorbunova and Andrei Seluanov of the University of Rochester have found that human cells undergoing oxidative stress caused by environmental chemicals or routine cellular processes produce a protein (SIRT6) that stimulates cells to repair DNA double-strand breaks, thought to be associated with premature aging and cancer. The team first measured levels of SIRT6 in stressed cells, then treated a second group of stressed cells with a drug that deactivates the protein. DNA repair in the second group stopped, confirming SIRT6′s role.  The team also found that SIRT6 acts in concert with another protein, called PARP1, to make the repairs. Furthermore, the team found that increased levels of SIRT6 lead to faster DNA repair. They suspect that the protein acts as a "master regulator," coordinating stress and DNA repair activities. Ref.: Zhiyong Mao, Christopher Hine, Xiao Tian, Michael Van Meter, Matthew Au, Amita Vaidya, Andrei Seluanov, and Vera Gorbunova. SIRT6 Promotes DNA Repair Under Stress by Activating PARP1. Science 17 June 2011: 1443-1446. [DOI:10.1126/science.1202723]
thinkahol *

YouTube - "The Business of Being Born" 2007 Trailer - 0 views

www.youtube.com/watch

business of being born

shared by thinkahol * on 24 Jun 10 - Cached
  • thinkahol * on 24 Jun 10
     
    Birth: it's a miracle. A rite of passage. A natural part of life. But more than anything, birth is a business. Compelled to find answers after a disappointing birth experience with her first child, actress Ricki Lake recruits filmmaker Abby Epstein to examine and question the way American women have babies. The film interlaces intimate birth stories with surprising historical, political and scientific insights and shocking statistics about the current maternity care system. When director Epstein discovers she is pregnant during the making of the film, the journey becomes even more personal. Should most births be viewed as a natural life process, or should every delivery be treated as a potentially catastrophic medical emergency?
Todd Suomela

MnCSE - Dancing with the Disco Institute - 0 views

www.mnscience.org/index.php

sts evolution biology philosophy history science eugenics intelligent-design import-delicious

shared by Todd Suomela on 25 Jan 09 - Cached
  • Todd Suomela on 25 Jan 09
     
    Historians of science know that the passage of the first sterilization laws at the beginning of the 20th century occurred during the "eclipse of Darwinism".
thinkahol *

Laser, electric fields combined for new 'lab-on-chip' technologies | KurzweilAI - 0 views

www.kurzweilai.net/r-new-lab-on-chip-technologies

Laser electric fields combined for new 'lab-on-chip' technologies | KurzweilAI

shared by thinkahol * on 11 Jul 11 - No Cached
  • thinkahol * on 11 Jul 11
     
    Researchers from Purdue University and colleagues are developing new technologies that combine a laser and electric fields to manipulate fluids and tiny particles such as bacteria, viruses, and DNA molecules for a wide range of potential applications, including medical diagnostics, testing food and water, crime-scene forensics, and pharmaceutical manufacturing.. This "hybrid optoelectric manipulation in microfluidics" technology could allow for innovative sensors and analytical devices for "lab-on-a-chip" applications, or miniature instruments that perform measurements normally requiring large laboratory equipment, the researchers said. The technology works by first using a red laser to position a droplet on a platform specially fabricated at Purdue. Next, a highly focused infrared laser is used to heat the droplets, and then electric fields cause the heated liquid to circulate in a "microfluidic vortex." This vortex is used to isolate specific types of particles in the circulating liquid, like a micro centrifuge. Particle concentrations replicate the size, location and shape of the infrared laser pattern. The technology can also be used in nanomanufacturing because it shows promise for the assembly of suspended particles (colloids), the researchers said. Ref.: Steven T. Wereley, et al., Hybrid opto-electric manipulation in microfluidics-opportunities and challenges, Lab on a Chip, 2011; 11 (13): 2135 [DOI: 10.1039/C1LC20208A]
Todd Suomela

The Bohr paradox - physicsworld.com - 0 views

physicsworld.com/...33963

physics sts history quantum-mechanics

shared by Todd Suomela on 25 Jan 09 - Cached
  • Why? The best explanation I have heard is advanced by the physicist John H Marburger, who is currently science advisor to US President George Bush. By 1930, Marburger points out, physicists had found a perfectly adequate way of representing classical concepts within the quantum framework using Hilbert (infinite-dimensional) space. Quantum systems, he says, “live” in Hilbert space, and the concepts of position and momentum, for instance, are associated with different sets of coordinate axes that do not line up with each other, thereby resulting in the situation captured in ordinary-language terms by complementarity.“It’s a clear, logical and consistent way of framing the complementarity issue,” Marburger explained to me. “It clarifies how quantum phenomena are represented in alternative classical ‘pictures’, and it fits in beautifully with the rest of physics. The clarity of this scheme removes much of the mysticism surrounding complementarity. What happened was like a gestalt-switch, from a struggle to view microscopic nature from a classical point of view to an acceptance of the Hilbert-space picture, from which classical concepts emerged naturally. Bohr brokered that transition.”
  • In his book Niels Bohr’s Times, the physicist Abraham Pais captures a paradox in his subject’s legacy by quoting three conflicting assessments. Pais cites Max Born, of the first generation of quantum physics, and Werner Heisenberg, of the second, as saying that Bohr had a greater influence on physics and physicists than any other scientist. Yet Pais also reports a distinguished younger colleague asking with puzzlement and scepticism “What did Bohr really do?”.
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