It should have been clear to Neanderthal, as it is now clear to us in the 21st century, that something new and big had appeared -- a new biological and geological force. A number of scientists (Richard Klein, Ian Tattersall, William Calvin, among many others) think that the "something" that happened 50,000 years ago was the invention of language. Up until this point, humanoids were smart. They could make crude tools in a hit or miss way and handle fire – perhaps like an exceedingly smart chimp. The African hominin's growing brain size and physical stature had leveled off its increase, but evolution continued inside the brain. "What happened 50,000 years ago," says Klein, "was a change in the operating system of humans. Perhaps a point mutation effected the way the brain is wired that allowed languages, as we understand language today: rapidly produced, articulate speech." Instead of acquiring a larger brain, as the Neanderthal and Erectus did, Sapien gained a rewired brain. Language altered the Neanderthal-type mind, and allowed Sapien minds for the first time to invent with purpose and deliberation. Philosopher Daniel Dennet crows in elegant language: "There is no step more uplifting, more momentous in the history of mind design, than the invention of language. When Homo sapiens became the beneficiary of this invention, the species stepped into a slingshot that has launched it far beyond all other earthly species." The creation of language was the first singularity for humans. It changed everything. Life after language was unimaginable to those on the far side before it.
thinkahol * on 16 Jul 11A 36-year-old man has received the world's first synthetic trachea, made from a synthetic scaffold seeded with his own stem cells, in an operation at the Karolinska University Hospital in Stockholm, Sweden. Professor Paolo Macchiarini of Karolinska University Hospital and Karolinska Institutet led an international team, including professor Alexander Seifalian from University College London, who designed and built the nanocomposite tracheal scaffold, and Harvard Bioscience, which produced a specifically designed bioreactor used to seed the scaffold with the patient´s own stem cells. The cells were grown on the scaffold inside the bioreactor for two days before transplantation to the patient. Because the cells used to regenerate the trachea were the patient's own, there has been no rejection of the transplant and the patient is not taking immunosuppressive drugs. "The big conceptual breakthrough is that we can move from transplanting organs to manufacturing them for patients," says David Green, the president of Harvard Bioscience in Holliston, Massachusetts. Transplantations of tissue-engineered windpipes with synthetic scaffolds in combination with the patient's own stem cells as a standard procedure means that patients will not have to wait for a suitable donor organ. Patients could benefit from earlier surgery and have a greater chance of cure. This would be of especially great value for children, since the availability of donor tracheas is much lower than for adult patients.
