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Sea Maskulrath

Anti-cloning advocate Fred Sauer files to run for governor - 0 views

  • Anti-cloning advocate Fred Sauer files to run for governor
  • . LOUIS • Anti-cloning activist Fred Sauer may be looking to convert his legal victory into a political win.
  • Although Sauer is no stranger to generating publicity for his causes, he added his name to the Republican contenders for governor with little fanfare Monday morning.
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  • This year, however, Sauer won a round in court, convincing a judge to rule against Gov. Jay Nixon's signature bio-tech initiative, MOSIRA, which seeks to help tech start-ups in the state.
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    As with all the processing happening around the world there are also people with money and power that are also trying to prevent cloning form happening. 
Sea Maskulrath

Shocking pictures show group of 14-year-old schoolboys puffing on shisha pipes in bar |... - 0 views

  • A video of a group of 14-year-olds smoking shisha pipes in a bar has emerged online, horrifying parents and anti-smoking campaigners.
  • They want to warn shisha enthusiasts it isn't a safe alternative to cigarettes - smoking a pipe for an hour is the the equivalent of puffing away on 100 cigarettes.
  • ‘Smoke from tobacco contains a number of carcinogens which damage the DNA in cells,’
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  • ‘Just one damaged cell can divide and multiply uncontrollably and quite quickly develop into a large tumour. This is what causes lung cancer,
  • around from person to person, this raises the risk of transmitting diseases such as tuberculosi
  • As the mouthpiece is passe
  • nd hepatitis.
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    WOW, I guess we know we had to stop shisha right? unbelievable 
nidthamsirisup

Study suggests why some animals live longer - 1 views

    • nidthamsirisup
       
      A new method to detect proteins associated with longevity which helps further our understanding into why some animals live longer than others.
  • The study, led by Dr. Joao Pedro Magalhaes and postgraduate student, Yang Li, is the first to show evolutionary patterns in biological repair systems in long-lived animals and could, in the future, be used to help develop anti-ageing interventions by identifying proteins in long-lived species that better respond to, for example, DNA damage
  • these species have optimised pathways that repair molecular damage, compared to shorter-lived animals, such as mice
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  • found a similar pattern in proteins associated with metabolism, cholesterol and pathways involved in the recycling of proteins
  • Proteins associated with the degradation of damaged proteins, a process that has been connected to ageing, were also linked with the evolution of longevity in mammals.
  • If we can identify the proteins that allow some species to live longer than others we could use this knowledge to improve human health and slow the ageing process.
  • “We developed a method to detect proteins whose molecular evolution correlates with longevity of a species. The proteins we detected changed in a particular pattern, suggesting that evolution of these proteins was not by accident, but rather by design to cope with the biological processes impacted by ageing, such as DNA damage. The results suggest that long-lived animals were able to optimise bodily repair which will help them fend off the ageing process.”
Sasicha Manupipatpong

Divergent evolution illuminated: Light shed on reasons behind genome differences betwee... - 0 views

  • divergent evolution of the genomes of different groups of species
  • three large domains: Archaea, Bacteria and Eukarya
  • genomes of each group have evolved towards distinct structures that have favored their separation
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  • connection between the function of enzymes and the composition of the genomes shed light on the evolution and structure of genes
  • analyzed the distribution and abundance of transfer RNA genes
  • structure of genomes was adapted to the activity of some enzymes, which differ for Bacteria and for Eukarya and are absent in Archaea
  • activity of these enzymes modifies tRNAs, allowing them to recognize up to three distinct codons
    • Sasicha Manupipatpong
       
      Prior to the study, it was understood that tRNA's have a specific anti-codon sequence which would recognize a single mRNA codon with the complementary sequence. Does this mean that the tRNA also attaches to different amino acids as well? How does the tRNA differentiate between the different amino acids it is at that moment carrying and the codon it matches with on the mRNA--does it change shape according to which amino acid is attached to it?
  • activity of the bacterial and eukaryal enzymes is different, which explains why the genomes and the gene composition of bacteria, eukarya, and archaea have diverged
  • relation between genome structure and the speed of protein synthesis from its genes
  • greater the abundance of a protein in a cell the higher the number of triplets found in its gene sequence that can be read by modified tRNAs
  • biotechnology as the discovery of the relevance of these modifications will allow an improvement in the industrial production of proteins
  • another parameter with which to optimize the synthesis of proteins from a gene
  • human insulin is "manufactured" in bacteria and our discovery would allow this production to be increased if we take into account the activity of these enzymes
  • relevant for the study of cancer: "it is possible that these modification enzymes are over-represented in some kinds of cancer. In fact, this would be logical because cancer cells are highly efficient in producing proteins."
  • demonstrates how organisms have evolved in a different manner to achieve better adaptations and to have optimum protein translation efficiency
  • don't exactly know why these enzymes appear or why they are different in bacteria and in eukaryotes but it's clear that they contribute to the separation of genomes of these two groups
  • genetic code is the same
  • what has changed is the relative importance of different codons of the code
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    A recent study uncovers the reasons for the divergent evolution of the genomes of different species. The findings provide information about tRNA modifications which may prove useful in the field of biotechnology, specifically in the industrial production of proteins
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