PHE - Resources

"Jennifer M Radin, PhD Nathan E Wineinger, PhD Prof Eric J Topol, MD Steven R Steinhubl, MD"

recommended by Erin Raskin

Interactive Map - Global to city range.

Recommended by DeAunne Denmark, MD, PhD : "The projects these companies are working on can be organized into three distinct groups: Diagnostics: Quickly and effectively detecting the disease in the first place Treatments: Alleviating symptoms so people who have disease experience milder symptoms, and lowering the overall mortality rate Vaccines: Preventing transmission by making the population immune to COVID-19"

Explanation from DeAunne Denmark, MD, PhD : And just to clarify for all, since all of the testing jargon and landscape can be *extremely* confusing, especially now: The FDA has currently relaxed regulations for COVID diagnostics under "Emergency Use" (EUA). This authorizes, not approves, test kits, machines and devices to run those kits, and all other aspects involved in diagnostic testing. Authorize vs approve are very different animals under FDA. And you will see this repeatedly emphasized on the FDA site. But most often neglected, skipped over, mistaken in the wider press. Many articles and press releases use "approve" which is technically wrong - they mean authorize, or "grant use", or "use will not be objected to by FDA." If you have the stamina, I highly recommended reading as much of this as you can: https://www.fda.gov/medical-devices/emergency-situations-medical-devices/faqs-diagnostic-testing-sars-cov-2 "Validation" is yet an additional aspect that is probably the grayest zone of all, since it is left to each company/testing entity how exactly this is done. Validation can range from excellent to pretty cruddy science and still meet FDA "standards". These will be the devilish details we need to sort out re: collaborating with partners. And will unfortunately likely be a big mess for many outpatient Drs trying to figure out which test to order.

"To contribute supplies to one of the below organizations, please click directly on their corresponding links."

Source: LA Times 4/8/2020 As of Tuesday, California said it had results for 143,172 tests - or 362 per 100,000 people. That's a sharp increase from two weeks ago when just 39 of every 100,000 residents had been tested. Yet for all its deep sources of innovation, the state is behind the national average of 596 tests per 100,000, according to the COVID Tracking Project. In New York, which has far more people hospitalized with severe symptoms, testing has reached 1,748 of every 100,000.

"The Microsetta Initiative and its subsidiaries, including the American Gut Project, have pivoted to COVID-19 research, and are revising our kits to support this effort. We are working as hard as we can, but please be patient as these changes have required a complete overhaul of our infrastructure. Please check back soon: we are setting up a form to gather information about people who are interested in receiving a kit when they are ready."

Download the Mydatahelps app -- "When your heart beats faster than usual, it can mean that you're coming down with a cold, flu, coronavirus, or other viral infection. That's the conclusion of recent medical research. So wearable devices that measure your resting heart rate-made by Apple, Fitbit, Garmin, and others-might help scientists spot viral outbreaks, and also give you more insight into your own health. At Scripps Research, we've designed DETECT (Digital Engagement & Tracking for Early Control & Treatment), a study that will monitor your heart rate and allow you to record symptoms like fever or coughing."

"Join us in our crowdsourced effort to analyze and predict potential COVID-19 cases by donating your wearables data. " This page describes study participation opportunities: Wearables Data Study, Molecular Profiling, and Global Relief Coalition

Wolfram is offering free access to their data tools for educators and researchers.

In this video, Dr. Guarneri explains basic antibody concepts and shares some insights from small N research at Pacific Pearl

"How Will Coronavirus Patients Flow through Health Services? Many of you have called asking to be tested for Coronavirus. Given recent testing challenges, the CDC and County have provided physicians with a simple coronavirus patient testing & care health services flowchart. As you can see, if symptoms are mild, testing is not indicated at this time. It is my hope that we will soon be able to test everyone! The 211 number mentioned below is a San Diego County information line that helps people efficiently access appropriate services, and provides vital data and trend information. The website for 211 is https://211sandiego.org/"

This overview article mentions Ben Smarr's work along with Eric Topol's research and a newly launched project from Stanford.

Recommended by Dr. Michael Kurisu D.O. 4/15/2020 Good summary. Not scientific or too detailed but good overall big picture view

This is an on-demand webinar. "Statistical errors are all too common in medical literature, and contribute to the reproducibility crisis currently plaguing science. Fortunately, you don't need a degree in statistics to catch these errors. While some errors are impossible to spot without access to the underlying dataset, many are detectable just by reviewing the information available in the paper. In many cases nothing more than common sense and simple arithmetic is required. In addition, there is an ever-increasing number of free, easy-to-use online statistical tools that facilitate error detection."

Recommended by DeAunne Denmark, MD, PhD & Meg Sweeney