Contents contributed and discussions participated by Dennis OConnor
Facebook reportedly collecting user data via hospital websites - 0 views
(13) 'Tumors just vanished': Cancer patients now in remission after drug trial - YouTube - 0 views
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"Treatment with the immunotherapy dostarlimab showed promising results in a small trial of more than a dozen rectal cancer patients, according to new research, but further study is needed and it is too early to call it a cure. CNN's Erin Burnett speaks to Dr. Andrea Cercek, an oncologist at Memorial Sloan Kettering Cancer Center."
Covid hasn't given up all its secrets. Here are 6 mysteries experts hope to unravel - 0 views
Growth after trauma - 0 views
The Five Minute Journal® - Simplest, most effective way to be happier. - Inte... - 0 views
Oji Emotions - 0 views
Personal Science… by Gary Isaac Wolf in collaboration with Thomas Blomseth Ch... - 0 views
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"Thank you for considering buying our book, Personal Science: Learning to Observe. The book presents a step-by-step approach to exploring your personal questions with empirical methods. It contains no advice whatsoever on what treatments or medicines or diets or vitamins or exercises are worth trying. Instead, it offers meta-advice; that is, advice on how to know if the things that you try actually work the way you expect, and advice about how to develop reasonable new ideas of things to try."
Communities - Luna - 0 views
Self-Tracking (The MIT Press Essential Knowledge series): Neff, Gina, Nafus, Dawn: 9780... - 0 views
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"What happens when people turn their everyday experience into data: an introduction to the essential ideas and key challenges of self-tracking. People keep track. In the eighteenth century, Benjamin Franklin kept charts of time spent and virtues lived up to. Today, people use technology to self-track: hours slept, steps taken, calories consumed, medications administered. Ninety million wearable sensors were shipped in 2014 to help us gather data about our lives. This book examines how people record, analyze, and reflect on this data, looking at the tools they use and the communities they become part of. Gina Neff and Dawn Nafus describe what happens when people turn their everyday experience-in particular, health and wellness-related experience-into data, and offer an introduction to the essential ideas and key challenges of using these technologies. They consider self-tracking as a social and cultural phenomenon, describing not only the use of data as a kind of mirror of the self but also how this enables people to connect to, and learn from, others. Neff and Nafus consider what's at stake: who wants our data and why; the practices of serious self-tracking enthusiasts; the design of commercial self-tracking technology; and how self-tracking can fill gaps in the healthcare system. Today, no one can lead an entirely untracked life. Neff and Nafus show us how to use data in a way that empowers and educates."
San Diego Botanic Garden launches medicinal plant research program - North Coast Current - 0 views
Nostalgia can relieve pain | EurekAlert! - 0 views
Caught in the trap of chronic illness - The Boston Globe - 0 views
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"Dignity during the process of seeking treatment is a tall order. It requires first and foremost that a patient be believed. This, O'Rourke soon discovers, is much harder than it looks. At appointments, she's often met with disbelief, skepticism, and suspicion - daunting hurdles for her shot at wellness that highlight a gendered conundrum. Autoimmune disease disproportionately affects women (they make up 80 percent of patients), but health care professionals are less likely to take women's concerns seriously."
A unified genealogy of modern and ancient genomes - 0 views
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"Genomics and human ancestral genealogy Hundreds of thousands of modern human genomes and thousands of ancient human genomes have been generated to date. However, different methods and data quality can make comparisons among them difficult. Furthermore, every human genome contains segments from ancestries of varying ages. Wohns et al. applied a tree recording method to ancient and modern human genomes to generate a unified human genealogy (see the Perspective by Rees and Andrés). This method allows for missing and erroneous data and uses ancient genomes to calibrate genomic coalescent times. This permits us to determine how our genomes have changed over time and between populations, informing upon the evolution of our species. -LMZ"
Cas9-mediated gene editing in the black-legged tick, Ixodes scapularis, by embryo injec... - 0 views
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"Despite their capacity to acquire and pass on an array of debilitating pathogens, research on ticks has lagged behind other arthropod vectors, such as mosquitoes, largely because of challenges in applying available genetic and molecular tools. CRISPR-Cas9 is transforming non-model organism research; however, successful gene editing has not yet been reported in ticks. Technical challenges for injecting tick embryos to attempt gene editing have further slowed research progress. Currently, no embryo injection protocol exists for any chelicerate species, including ticks. Herein, we report a successful embryo injection protocol for the black-legged tick, Ixodes scapularis, and the use of this protocol for genome editing with CRISPR-Cas9. We also demonstrate that the ReMOT Control technique could be successfully used to generate genome mutations outside Insecta. Our results provide innovative tools to the tick research community that are essential for advancing our understanding of the molecular mechanisms governing pathogen transmission by tick vectors and the underlying biology of host-vector-pathogen interactions."
Yale Researchers Develop mRNA-Based Lyme Disease Vaccine - 0 views
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"Yale University researchers have developed a novel vaccine that in guinea pigs offers protection against infection by the bacterium that causes Lyme disease and may also combat other tick-borne diseases. Instead of triggering an immune response against a particular pathogen, the new vaccine prompts a quick response in the skin to components of tick saliva, limiting the amount of time that ticks have to feed upon and infect the host, the study shows. The vaccine is delivered by the same mRNA technology that has proved so effective against COVID-19."
iHope Genetic Health - 0 views
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"iHopeTM Genetic Health (iGH) will eliminate the barriers to genomic insights for tens of thousands of individuals across the globe each year by addressing access to high-quality clinical whole genome sequencing (cWGS) as well as education and support. Leveraging contributions of genomic sequencing technology from Illumina and donations from philanthropists and technology and logistics partners, iGH will provide awards of reagents and, where necessary, sequencers and software to enable genomic testing across the globe. iGH will provide cWGS and patient support services for undiagnosed individuals in low and middle income countries1 (LMICs) and low-to-moderate income2 (LMI) households across the globe and in the United States (US) respectively. Over time iGH will develop in-country, sustainable solutions for communities with little to no access to genomic care."
Partnering Guide - CIRCLE for the Multiple Chronic Conditions Stories and Dialogues - 0 views
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"Multiple Chronic Conditions Community: People who live with multiple complex, chronic, persistent, painful and often mystifying health conditions are not only resilient but wise due to the expertise gained from managing MCCs and navigating healthcare systems. Comparative Effectiveness Research (CER) can benefit from their expertise. People who help patients manage their health whether as professional care providers, insurance providers, policy makers, researchers, family or friends who care each day about these patients are also considered members of the MCC community. Building a diverse multi-stakeholder team to design CER studies to improve health outcomes for MCC patients requires a thoughtful and person centered approach to building a research community. "
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