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As the general election campaign continues, Labour is set to introduce a series of policies aimed at supporting small businesses. On Saturday, Sir Keir Starmer, alongside shadow chancellor Rachel Reeves and other shadow cabinet ministers, is expected to unveil the party's plans for the sector. Key proposals include an overhaul of the business rates system to enable high street shops to compete with online giants and ensure access to high street banking services by accelerating the establishment of banking hubs. Labour will also commit to addressing the issue of late payment of invoices by requiring large businesses to disclose their payment practices and "revitalise" high streets by tackling antisocial behaviour. Sir Keir described small businesses as "the beating heart of driving growth and creating jobs for local people."

The Johnson & Johnson drug Darzalex showed promise in helping keep a precancerous condition from progressing to the blood cancer multiple myeloma for those at high risk, according to results from a trial presented at the American Society of Hematology meeting in San Diego. Darzalex, a monoclonal antibody that targets a protein found on the surface of myeloma cells known as CD38, significantly reduced patients' risk of developing the blood cancer and improved their survival in an international late-stage trial. "These results are a major advancement in the treatment of high-risk smoldering multiple myeloma," study leader Dr. S. Vincent Rajkumar of the Mayo Clinic Comprehensive Cancer Center in Rochester, Minnesota said in a statement. In smoldering multiple myeloma, abnormal plasma cells accumulate in the bone marrow. As the abnormal cells and certain proteins accumulate, a patient's risk for cancer increases.

The renowned health and beauty chain has announced impressive annual sales and profit figures, following the expansion of its British high street estate. According to a report by The Times, Superdrug's pre-tax profits jumped by 43.6 per cent to £111.6 million in the year ending December 2023 compared to the previous year. The company's revenue also experienced significant growth, rising by 11.8 per cent to reach £1.52 billion, marking its third consecutive year of market share growth. Key factors driving this growth include the opening of 14 new stores across strategic locations such as The Trafford Centre in Manchester and Brent Cross shopping centre in north London, and the refitting of 45 stores last year. Additionally, the continued expansion of its cheaper, own-label products, along with exclusive launches from brands like Bioré SPF, Nyx X Barbie, and Billie Eilish fragrances, significantly contributed to a 4.2 per cent year-on-year increase in Superdrug's sales volume.

For patients with stage 4 or 5 chronic kidney disease and hepatitis C virus (HCV) infection, 12 weeks of treatment with glecaprevir and pibrentasvir results in a high rate of sustained virologic response, according to a study published online Oct. 11 in the New England Journal of Medicine. Edward Gane, M.D., from Auckland City Hospital in New Zealand, and colleagues conducted a multicenter trial to examine the efficacy and safety of combination treatment with the NS3/4A protease inhibitor glecaprevir and the NS5A inhibitor pibrentasvir for 12 weeks in adults with HCV infection and compensated liver disease with severe renal impairment, dependence on dialysis, or both. Participants had stage 4 or 5 chronic kidney disease. One hundred four patients were enrolled in the trial. The researchers found that the sustained virologic response rate was 98 percent. During treatment, none of the patients had virologic failure, and none had a virologic relapse after the end of treatment. Pruritus, fatigue, and nausea were reported in at least 10 percent of the patients. Twenty-four percent of the patients reported serious adverse events. Because of adverse events, four patients discontinued the trial treatment prematurely; three of these had sustained virologic response.

The mental health challenges faced by pharmacists are a significant concern that is frequently discussed within the industry today. The Royal Pharmaceutical Society's (RPS) fifth annual workforce wellbeing survey indicated that 86% of pharmacists are at a high risk of burnout. Key factors contributing to this burnout include inadequate staffing, poor work-life balance, and extended working hours. Mental Health UK also identifies burnout as one of the most pressing issues affecting modern workplaces. According to the charity's Burnout Report released in January 2024, 9 in 10 adults in the UK reported experiencing high or extreme stress in the past year. The charity warns that burnout may increase the risk of developing mental health conditions such as depression or anxiety, underscoring the need for serious attention. Today, on World Mental Health Day, we reflect on the theme, "It is time to prioritise mental health in the workplace."

As local GP services face increasing pressure, the role of pharmacists in managing minor ailments such as cold and cough has become more crucial than ever. Considering environmental and lifestyle factors, such as pollution levels, pollen counts, smoking, and diet, is essential for the effective management of respiratory conditions. In this article, experts explain how pharmacists can leverage these factors to provide more comprehensive advice to patients for managing cold and cough symptoms. Dr Roger Henderson, GP and spokesperson for Olbas, says: "Environmental factors play a critical role in the exacerbation and management of respiratory conditions. For example, high pollution levels can aggravate cold and cough symptoms, particularly in areas where air quality can drastically fluctuate. "By assessing real-time pollution data, pharmacists can advise patients to take precautions on days when pollution levels are high." Air pollution is well known to increase the risk of certain respiratory diseases.

The UK's performance in hospital-based care is falling behind other high-income countries, according to a new report published by the Health Foundation. For hospital care waiting times, the UK ranked among the worst in a public survey of 10 nations, with 11 per cent of people waiting a year or more for a specialist appointment and 19 per cent facing the same delay for non-emergency surgery. Only Canada had comparable figures. The report published on Thursday (22 August) also pointed out that waiting times for specialist appointments have increased more rapidly in the UK than in other countries. In 2023, 61 per cent of people in the UK reported waiting more than four weeks for a specialist appointment, a significant rise from just 14 per cent in 2013. Over 21,000 people from across 10 developed countries, including over 3,000 from the UK, participated in the 2023 Commonwealth Fund survey.

Expressing apprehension over the concerning decline in the nursing workforce, Sir Julian Hartley, CEO of NHS Providers, urged the forthcoming government to bolster investment in nursing education and enhance support for student nurses. Recent analysis from the Royal College of Nursing (RCN) has projected that the NHS Long Term Workforce Plan will fall short by 10,000 new nurses by 2025. Commenting on the RCN analysis, Sir Hartley underscored the critical importance of having an adequate number of nurses to ensure the delivery of safe, high-quality patient care. "Without enough nurses, the delivery of safe, high-quality patient care is compromised," he said. He cautioned that the predicted shortfall in nurses would exacerbate existing pressures on the NHS, resulting in long waiting times, delayed treatments and staff burnout.

NHS England has announced a phased implementation for mandatory multi-sector rotations in the Foundation Pharmacist Training Programme, delaying the full rollout to the 2027/28 training year. Under the General Pharmaceutical Council's Standards for Initial Education and Training of Pharmacists (2021), multi-sector rotations - where trainees spend at least 13 weeks in a different pharmacy setting- were initially planned for all trainees starting in 2026/27. These rotations are designed to enhance pharmacists' adaptability, multi-professional collaboration, and ability to deliver person-centred care across healthcare systems. Acknowledging significant progress from pharmacy employers in developing these programmes, NHS England cited current workforce pressures as a key reason for introducing a phased approach. "We are mindful of the current pressures faced by pharmacy teams and the broader healthcare sector and greatly appreciate your continued commitment to delivering high-quality training. To support pharmacy teams in continuing to deliver high quality training, mandatory rotations will be delayed, and a phased approach will be implemented," David Webb, chief pharmaceutical officer for England and Samantha Illingworth, director of education quality and reform at NHS England, wrote in a letter to training programme providers.

The General Pharmaceutical Council (GPhC) has published updated guidance on online pharmacy services in Great Britain, introducing additional safeguards to prevent unsafe supply of high-risk medicines, including weight loss injections. Under the new rules, medicines used for weight-management and medicines requiring physical examination before a prescribing decision is made have been added to the list of high-risk medicines. When prescribing these medicines, prescribers can no longer rely solely on online questionnaires. Instead, they must independently verify patient information, either through timely two-way communication with the person, accessing the person's clinical records, or contacting the person's GP, their regular prescriber, or a third-party provider. These measures aim to prevent individuals from providing false information to obtain medicines that may not be clinically appropriate for them, reducing potential harm. The pharmacy regulator updated its guidance in response to concerns identified relating to unsafe prescribing and supply of medicines online.

Superdrug is bolstering its physical presence by launching 25 new stores this year as it celebrates its 60th year on the British high street. Additionally, the health and beauty retailer has announced plans to extend seven of its existing branches and refit another 60 throughout 2024. However, the retailer has confirmed the locations for only four upcoming stores - Wheatley Centre Shopping Parkin Doncaster, St David's Centre in Cardiff, Bluewater Shopping Centre and Westfield Stratford City. As reported by Mirror, the Donacaster site is expected to open by the end of this month, followed by the relocation of its existing Cardiff store to a new 11,3000 sq. ft space shortly thereafter. Superdrug is also shifting its Westfield Stratford City store, doubling its size to 9,892 sq. ft. Likely to be opened in the summer, it will be one of the retailer's biggest stores.

Christie & Co, a specialist business property adviser, recently finalised the sale of two pharmacies-one located in Wales and the other in Hampshire. Sylvia Williams Chemist, a well-performing community pharmacy located on the main high street of the Vale of Glamorgan market town of Cowbridge, has been sold after an impressive 50 years of ownership. Dispensing an average of 12,500 items monthly, the business has been owned by Kate Thomas and her family for nearly 50 years. It was put on the market to enable her retirement and allow her to focus on other interests, the broker said. The pharmacy has been purchased by Zaid Salih, making it his second pharmacy acquisition. Jonathan Board, Director - Medical at Christie & Co, who handled the sale, said that Sylvia Williams Chemist attracted a wide range of buyers.

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nOriginally Bubble Gum was developed by growers in Indiana. From there the genetics moved to New England and eventually Holland. It took many generations to finally produce a stable Bubble Gum with the characteristic sweet smell and euphoric high. Bubble Gum was the winner of two awards in the Cannabis Cup of '94, and the 2nd place winner in '95 and again in '99.

Provision of free lateral flow tests could end in the UK, and prime minister Boris Johnson is expected to make the big announcement within weeks, The Sunday Times has reported. The report said that in future free test kits could be provided only in high-risk settings such as care homes, hospitals and schools, and to people with symptoms, and contact tracing by NHS Test and Trace is also expected to be scaled back. The newspaper quoted a senior Whitehall source as saying: "I don't think we are in a world where we can continue to hand out free lateral flow tests to everybody. "It's likely we will move to a scenario where there is less testing, but we have a capacity to ramp it up if necessary." It added that more than £6 billion of public money has already been spent on mass testing. Separately, Dr Clive Dix, former chairman of the country's vaccine task force said that Covid-19 should now be treated as a flu, and mass vaccination campaigns should end after the booster shots in the UK.

The General Pharmaceutical Council (GPhC) is mulling over introducing "differentiated fees options to cover the increased regulation needed for online pharmacies." In papers published by the regulator ahead of its meeting on Thursday (December 9), it noted that with increase in number of online and distance-selling pharmacies, the regulation has become "potentially more complex and resource intensive." It highlighted that service provided by online pharmacies pose a high risk "in terms of professional care and professional standards". Only 63 per cent of the 187 inspections of online pharmacies since April 2019, met all standards, against the overall benchmark of 84 per cent, the GPhC said. The independent regulator informed that swift enforcement action has been taken against 48 online pharmacies to address patient safety risks, including 40 conditions notices and 11 improvement notices.

Aspire Pharma Limited has reaffirmed its commitment to combating prostate cancer by adding leuprorelin acetate as a branded generic to its oncology portfolio. This move solidifies Aspire's position as a leading specialty generics enterprise. Leuprorelin acetate is a hormone therapy recommended for patients with high-risk localized, locally advanced, and metastatic prostate cancer. It serves as an alternative to surgical castration for locally advanced cases. A pre-filled syringe containing 11.25mg of leuprorelin acetate (equivalent to 10.72 mg leuprorelin) is injected subcutaneously into the abdomen, providing a vital treatment option for patients.

"We need to fix the front door to our NHS by investing in community pharmacy," asserts Daisy Cooper as more and more pharmacies "worry about the future of their business." Reflecting on the challenges faced by pharmacists during the pandemic, she emphasised their pivotal role in launching vaccination schemes across communities and the larger role pharmacies play in complementing traditional NHS facilities. Cooper recalls her collaboration with local pharmacies in St. Albans, where she worked hand in glove with them to address challenges faced by pharmacists to obtain information from NHS England regarding protocols and procedures. She told Pharmacy Business reporter that she had to work out something "hand in glove to help them get those vaccinated schemes up and running, as pharmacies were desperate to take part in the vaccination scheme" in her constituency. Describing their unique selling point (USP), Cooper emphasised the convenience and immediacy of pharmacies located in high street areas and warned that pharmacy closures "should be a real wake up call for the government."

Nestled in the heart of a bustling high street and a housing estate, at Lincoln Pharmacy, part of Mildcare Ltd Group, in Tower Hamlets in London, the scene is a testament to resilience and innovation, where queues of people seek aid from a pharmacy technician stationed behind a glass window-a symbol of the enduring impact of the pandemic. Amidst the array of modern amenities at the pharmacy stands Atulkumar Patel, the proprietor and Independent Prescriber (IP) at Lincoln Pharmacy, whose vision has propelled the establishment into a beacon of progressive healthcare. Owner of two Pharmacies, Patel's team of 20 dispenses an average of 20,000 prescriptions monthly, maintaining an NHS/OTC split of 80/20. Recipient of the prestigious Independent Prescriber of the Year award at the Pharmacy Business Awards 2023, Patel reflects on the pivotal moment when his pharmacy pioneered the rollout of COVID-19 vaccine jabs within the community. "When doctors' doors closed, pharmacy was the only place where people could get help and care," Patel recounts, emphasising the pivotal role pharmacies played during the crisis. Patel's dedication during the pandemic extended beyond mere service provision; it was about showcasing the untapped potential of pharmacies.