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Researchers have made dramatic inroads into the study of polygenic and other complex human diseases, due in large part to knowledge of the human genome sequence, the generation of widespread markers of genetic variation, and the development of new technologies that allow investigators to associate disease phenotypes with genetic loci. Although polygenic diseases are more common than single-gene disorders, studies of monogenic diseases provide an invaluable opportunity to learn about underlying molecular mechanisms, thereby contributing a great deal to our understanding of all forms of genetic disease.

Teacher site with many resources

In depth explanation of polygenic traits, including Rh.

Worksheet: codominance lethal genes multiple alleles polygenic traits

Discover more types of non-Mendelian inheritance such as incomplete dominance and codominance with the Amoeba Sisters! This video uses vocabulary that was previously defined in the Amoeba Sisters Monohybrid Crosses video.

SciShow explains the genetics -- and physics -- behind why blue eyes are blue, and what the future may be for the trait. Spoiler alert: Blue eyes aren't really blue! SciShow explains!

When babies are born, their eyes and hair are one color, but change within the first few years of their life! Why do hair and eye colors change? Trace explains the process of inheriting certain traits from your parents, and discusses why the colors change!

The 18-year-olds from Gloucester, U.K. are two of the five children born to their Caucasian father and "half-Jamaican" mother, World Wide Features reports. While their other siblings have a blend of features from their parents, Lucy and Maria are opposites: Lucy has fair skin and red hair, while Maria has caramel skin and dark hair.

This case is based on Kate Chopin's short story "Desiree's Baby," a tragic tale of race and gender in antebellum Louisiana first published in 1893. Students read the story and then answer a series of questions about the genetics and evolution of skin color. The case was developed for a general biology course organized around the general theme of evolution. It could also be used in anthropology and biology courses for non-majors.

There are few areas of science more fiercely contested than the issue of what makes us who we are. Are we products of our environments or the embodiment of our genes? Is nature the governing force behind our behaviour or is it nurture? While almost everyone agrees that it's a mixture of both, there has been no end of disagreement about which is the dominant influence.